Niels Erik Skakkebæk
Affiliate Professor
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The Association of Reproductive Hormone Levels and All-Cause, Cancer, and Cardiovascular Disease Mortality in Men
Agergaard Holmboe, S., Vradi, E., Jensen, T. K., Linneberg, Allan René, Husemoen, L. L. N., Scheike, Thomas, Skakkebæk, Niels Erik, Juul, Anders & Andersson, A., Dec 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 12, p. 4472-4480 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low semen volume in 47 adolescents and adults with 47,XXY Klinefelter or 46,XX male syndrome
Aksglaede, L., Jørgensen, N., Skakkebæk, Niels Erik & Juul, Anders, 2008, In: International Journal of Andrology. 32, 4, p. 376-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in anti-Müllerian hormone (AMH) throughout the life span: a population-based study of 1027 healthy males from birth (cord blood) to the age of 69 years
Aksglaede, L., Sørensen, K., Boas, M., Mouritsen, A., Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, Allan René, Andersson, A., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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47,XXY Klinefelter syndrome: clinical characteristics and age-specific recommendations for medical management
Aksglaede, L., Link, K., Giwercman, A., Jørgensen, N., Skakkebæk, Niels Erik & Juul, Anders, 2013, In: American Journal of Medical Genetics. Part C: Seminars in Medical Genetics. 163, 1, p. 55-63 9 p.Research output: Contribution to journal › Journal article › Research
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Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts
Aksglaede, L., Andersson, A., Jørgensen, N., Jensen, T. K., Carlsen, E., McLachlan, R. I., Skakkebæk, Niels Erik, Petersen, Jørgen Holm & Juul, Anders, 1 Feb 2007, In: Clinical Endocrinology. 66, 2, p. 276-81 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serum concentrations of Anti-Müllerian Hormone (AMH) in 95 patients with Klinefelter syndrome with or without cryptorchidism
Aksglaede, L., Christiansen, P., Sørensen, K., Boas, M., Linneberg, Allan René, Main, Katharina Maria, Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 2011, In: Acta Paediatrica. 100, 6, p. 839-845 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF)-I, IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the Y chromosome (SRY)-positive 46,XX karyotypes
Aksglaede, L., Skakkebæk, Niels Erik & Juul, Anders, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 1, p. 169-176 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High normal testosterone levels in infants with non-mosaic Klinefelter's syndrome
Aksglaede, L., Petersen, Jørgen Holm, Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2007, In: European Journal of Endocrinology. 157, 3, p. 345-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The sensitivity of the child to sex steroids: possible impact of exogenous estrogens
Aksglaede, L., Juul, Anders, Leffers, H., Skakkebæk, Niels Erik & Andersson, A., 2006, In: Human Reproduction Update. 12, 4, p. 341-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent decline in age at breast development: the Copenhagen Puberty Study
Aksglaede, L., Sørensen, K., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Juul, Anders, 2009, In: Pediatrics Electronic Pages. 123, 5, p. e932-9Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience
Aksglaede, L., Skakkebæk, Niels Erik, Almstrup, Kristian & Juul, Anders, 1 Jun 2011, In: Acta Paediatrica. 100, 6, p. 793-806 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent decline in age at breast development: the Copenhagen Puberty Study
Aksglaede, L., Sørensen, K., Petersen, J. H., Skakkebæk, Niels Erik & Juul, Anders, 2009, In: Pediatrics. 123, 5, p. e932-9Research output: Contribution to journal › Journal article › Research › peer-review
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Natural history of seminiferous tubule degeneration in Klinefelter syndrome
Aksglaede, L., Wikström, A. M., Rajpert-De Meyts, E., Dunkel, L., Skakkebæk, Niels Erik & Juul, Anders, 2006, In: Human Reproduction Update. 12, 1, p. 39-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in Anti-Mullerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years
Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, Annette Korsholm, Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, Allan René, Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-5364 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in Anti-Müllerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years
Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, A. K. M., Hagen, C., Jensen, R., Petersen, Jørgen Holm, Linneberg, Allan René, Andersson, A., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-5364 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sex chromosome aneuploidy and anthropometry
Aksglæde, L., Skakkebæk, Niels Erik & Juul, Anders, 2011, Handbook of Anthropometry: Physical measures of human form in health and disease. SpringerResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Perinatal origin of testicular germ cell cancer: Possible involvement of developmental reprogramming
Almstrup, H. K., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 2012, Perinatal Programming: The State of the Art. Plagemann, A. (ed.). De Gruyter, p. 219-228 9 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells
Almstrup, Kristian, Nielsen, J. E., Mlynarska, O., Jansen, M. T., Jørgensen, A., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 12 Oct 2010, In: British Journal of Cancer. 103, 8, p. 1269-76 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening of subfertile men for testicular carcinoma in situ by an automated image analysis-based cytological test of the ejaculate
Almstrup, Kristian, Lippert, M., Mogensen, H. O., Nielsen, J. E., Hansen, J. D., Daugaard, G., Jørgensen, N., Foged, N., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e21-30; discussion e30-1Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours
Almstrup, Kristian, Høi-Hansen, Christina Engel, Nielsen, J. E., Wirkner, U., Ansorge, W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 23 May 2005, In: British Journal of Cancer. 92, 10, p. 1934-1941 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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From embryonic stem cells to testicular germ cell cancer-- should we be concerned?
Almstrup, Kristian, Sonne, Si Brask, Hoei-Hansen, C. E., Ottesen, A. M., Nielsen, J. E., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: International Journal of Andrology. 29, 1, p. 211-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of cell-type-specific gene expression during mouse spermatogenesis
Almstrup, Kristian, Nielsen, J. E., Hansen, M. A., Tanaka, M., Skakkebæk, Niels Erik & Leffers, H., Jun 2004, In: Biology of Reproduction. 70, 6, p. 1751-1761 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved gene expression signature of testicular carcinoma in situ
Almstrup, Kristian, Leffers, H., Lothe, R. A., Skakkebæk, Niels Erik, Sonne, Si Brask, Nielsen, J. E., Rajpert-De Meyts, E. & Skotheim, R. I., 2007, In: International Journal of Andrology. 30, 4, p. 292-303Research output: Contribution to journal › Journal article › Research › peer-review
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Perinatal origin of testicular germ cell cancer: Possible involvement of developmental reprogramming
Almstrup, Kristian, Meyts, E. R. D. & Skakkebæk, Niels Erik, 30 Nov 2011, Perinatal Programming: The State of the Art. Walter de Gruyter GmbH and Co. KG, p. 219-228 10 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling
Almstrup, Kristian, Høi-Hansen, Christina Engel, Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jul 2004, In: Cancer Research. 64, 14, p. 4736-4743 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ
Almstrup, Kristian, Ottesen, A. M., Sonne, Si Brask, Hoei-Hansen, C. E., Leffers, H., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 2005, In: Cell and Tissue Research. 322, 1, p. 159-65 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Paraoxonase 1 polymorphism and prenatal pesticide exposure associated with adverse cardiovascular risk profiles at school age
Andersen, H. R., Veje, C. W., Dalgård, C., Christiansen, L. T., Main, Katharina Maria, Nellemann, C. L., Murata, K., Jensen, T. K., Skakkebæk, Niels Erik & Grandjean, P., 2012, In: P L o S One. 7, 5, p. e36830Research output: Contribution to journal › Journal article › Research › peer-review
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Serum inhibin B in healthy pubertal and adolescent boys: relation to age, stage of puberty, and follicle-stimulating hormone, luteinizing hormone, testosterone, and estradiol levels
Andersson, A. M., Juul, Anders, Petersen, J. H., Müller, J., Groome, N. P. & Skakkebæk, Niels Erik, 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 12, p. 3976-81 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endocrine disrupters: we need research, biomonitoring and action
Andersson, A., Bay, K., Frederiksen, H. & Skakkebæk, Niels Erik, Jul 2016, In: Andrology. 4, 4, p. 556-60 5 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Adverse trends in male reproductive health: we may have reached a crucial 'tipping point'
Andersson, A., Jørgensen, N., Main, Katharina Maria, Toppari, J., Rajpert-De Meyts, E., Leffers, H., Juul, Anders, Jensen, T. K. & Skakkebæk, Niels Erik, 2008, In: International Journal of Andrology. 31, 2, p. 74-80 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proceedings of the 5th Copenhagen Workshop on endocrine disrupters: ubiquitous endocrine disrupters and possible human health effects. Preface
Andersson, A., Bay, K., Grigor, K. M., Toppari, J. & Skakkebæk, Niels Erik, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 251 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Special issue on the impact of endocrine disrupters on reproductive health
Andersson, A., Bay, K., Grigor, K. M., Meyts, E. R. & Skakkebæk, Niels Erik, 2012, In: International Journal of Andrology. 35, 3, p. 215Research output: Contribution to journal › Journal article › Research
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Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys
Andersson, A., Jensen, T. K., Juul, Anders, Petersen, Jørgen Holm, Jørgensen, T. & Skakkebæk, Niels Erik, 1 Dec 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4696-705 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Country-specific chemical signatures of persistent organic pollutants (POPs) in breast milk of French, Danish and Finnish women
Antignac, J. P., Main, Katharina Maria, Virtanen, H. E., Boquien, C. Y., Marchand, P., Venisseau, A., Guiffard, I., Bichon, E., Wohlfahrt-Veje, C., Legrand, S., Boscher, C., Skakkebæk, Niels Erik, Toppari, J. & Le Bizec, B., Nov 2016, In: Environmental Pollution. 218, p. 728-738 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone mineral density is preserved in men with idiopathic infertility
Antonio, L., Priskorn, L., Nordkap, L., Bang, A. K., Jensen, T. K., Skakkebæk, Niels Erik, Petersen, Jørgen Holm, Vanderschueren, D. & Jørgensen, N., 2020, In: Andrology. 8, 2, p. 315-322 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assumed non-persistent environmental chemicals in human adipose tissue; matrix stability and correlation with levels measured in urine and serum
Artacho-Cordón, F., Arrebola, J. P., Nielsen, O., Hernández, P., Skakkebæk, Niels Erik, Fernández, M. F., Andersson, A. M., Olea, N. & Frederiksen, H., Jul 2017, In: Environmental Research. 156, p. 120-127 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proposed Key Characteristics of Male Reproductive Toxicants as an Approach for Organizing and Evaluating Mechanistic Evidence in Human Health Hazard Assessments
Arzuaga, X., Smith, M. T., Gibbons, C. F., Skakkebæk, Niels Erik, Yost, E. E., Beverly, B. E. J., Hotchkiss, A. K., Hauser, R., Pagani, R. L., Schrader, S. M., Zeise, L. & Prins, G. S., 2019, In: Environmental Health Perspectives. 127, 6, p. 1-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Semen quality, reproductive hormones and fertility of men operated for hypospadias
Asklund, C., Jensen, T. K., Main, Katharina Maria, Sobotka, T., Skakkebæk, Niels Erik & Jørgensen, N., 1 Feb 2010, In: International Journal of Andrology. 33, 1, p. 80-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
Assens, M., Frederiksen, H., Petersen, Jørgen Holm, Larsen, T., Skakkebæk, Niels Erik, Juul, Anders, Andersson, A. & Main, Katharina Maria, 2019, In: Environment International. 123, p. 318-324 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?
Bang, A. K., Busch, A. S., Almstrup, Kristian, Gromoll, J., Kliesch, S., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders, Tüttelmann, F. & Jørgensen, N., 2018, In: Andrology. 6, 1, p. 176-183 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reply to ‘Paracetamol use in pregnancy — caution over causal inference from available data’; ‘Handle with care — interpretation, synthesis and dissemination of data on paracetamol in pregnancy’
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., M. Andrade, A., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 3, p. 192 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Paracetamol use during pregnancy — a call for precautionary action
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2021, In: Nature Reviews Endocrinology. 17, p. 757–766 10 p.Research output: Contribution to journal › Review › Research › peer-review
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Reply to ‘Paracetamol use in pregnancy — neglecting context promotes misinterpretation’
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Nature Reviews Endocrinology. 18, 1 p., 386.Research output: Contribution to journal › Letter › Research › peer-review
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Paracetamol Use During Pregnancy - A Call for Precautionary Action
Bauer, A. Z., Swan, S. H., Kriebel, D., Liew, Z., Taylor, H. S., Bornehag, C., Andrade, A. M., Olsen, J., Jensen, Rigmor Højland, Mitchell, R. T., Skakkebæk, Niels Erik, Jégou, B. & Kristensen, D. M., 2022, In: Obstetrical and Gynecological Survey. 77, 3, p. 133-134 2 p.Research output: Contribution to journal › Review › Research › peer-review
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Testicular dysgenesis syndrome: possible role of endocrine disrupters
Bay, K., Asklund, C., Skakkebæk, Niels Erik & Andersson, A., 1 Mar 2006, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 20, 1, p. 77-90 14 p.Research output: Contribution to journal › Journal article › Research
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Testicular descent: INSL3, testosterone, genes and the intrauterine milieu
Bay, K., Main, Katharina Maria, Toppari, J., Skakkebæk, Niels Erik & Medscape, M., 15 Mar 2011, In: Nature Reviews. Urology.Research output: Contribution to journal › Journal article › Research
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Insulin-like factor 3 levels in second-trimester amniotic fluid
Bay, K., Cohen, A. S., Jørgensen, Finn Stener, Jørgensen, C., Lind, A. M., Skakkebæk, Niels Erik & Andersson, A., 1 Oct 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4048-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism
Bay, K., Virtanen, H. E., Hartung, S., Ivell, R., Main, Katharina Maria, Skakkebæk, Niels Erik, Andersson, A., Toppari, J. & Nordic Cryptorchidism Study Group, N. C. S. G., 1 Oct 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 4020-7 8 p.Research output: Contribution to journal › Journal article › Research
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Cotinine concentrations in maternal serum and amniotic fluid during pregnancy and risk of testicular germ cell cancer in the offspring: A prospective nested case-control study
Beck, A. L., Uldbjerg, C. S., Lim, Youn-Hee, Coull, B. A., Sørensen, K. M., Utko, M. M., Wilkowski, B., Rantakokko, P., Bengtsson, M., Lindh, C., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Hauser, R., Juul, Anders & Bräuner, E. V., 2023, In: International Journal of Cancer. 154, 1, p. 71-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity
Belling, K., Russo, F., Jensen, A. B., Dalgaard, M. D., Westergaard, David, Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders & Brunak, Søren, 1 Apr 2017, In: Human Molecular Genetics. 26, 7, p. 1219-1229 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Science and policy on endocrine disrupters must not be mixed: a reply to a “common sense” intervention by toxicology journal editors
Bergman, Å., Andersson, A-M., Becher, G., van den Berg, M., Blumberg, B., Bjerregaard, P., Bornehag, C-G., Bornman, R., Brandt, I., Brian, J. V., Casey, S. C., Fowler, P. A., Frouin, H., Giudice, L. C., Iguchi, T., Hass, U., Jobling, S., Juul, A., Kidd, K. A., Kortenkamp, A. & 21 others, , 2013, In: Environmental Health. 12, 69, p. 1-4 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Germ cell neoplasia in situ (GCNIS): evolution of the current nomenclature for testicular pre-invasive germ cell malignancy
Berney, D. M., Looijenga, L. H. J., Idrees, M., Oosterhuis, J. W., Rajpert-De Meyts, E., Ulbright, T. M. & Skakkebæk, Niels Erik, Jul 2016, In: Histopathology. 69, 1, p. 7-10 4 p.Research output: Contribution to journal › Review › Research › peer-review
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Intranasalt gonadotropinfrigørende hormon (LH-RH) som behandling ved retentio testis
Bertelsen, A., Skakkebæk, Niels Erik, Mauritzen, K., Preuss, P., Pedersen, P. V. & Thorup, Jørgen Mogens, 15 Jun 1981, In: Ugeskrift for Laeger. 143, 25, p. 1595-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening for carcinoma in situ of the contralateral testis in patients with germinal testicular cancer
Berthelsen, Jens, Skakkebæk, Niels Erik, von der Maase, H., Sørensen, B. L. & Mogensen, P., 1982, In: British medical journal (Clinical research ed.). 285, 6356, p. 1683-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro investigation of endocrine disrupting effects of pesticides on Ca2+-signaling in human sperm cells through actions on the sperm-specific and steroid-activated CatSper Ca2+-channel
Birch, Michala Rosa, Johansen, M., Skakkebæk, Niels Erik, Andersson, A. & Rehfeld, Anders Aagaard, 2022, In: Environment International. 167, 15 p., 107399.Research output: Contribution to journal › Journal article › Research › peer-review
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Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm
Birch, M. R., Dissing, Steen, Skakkebæk, Niels Erik & Rehfeld, Anders Aagaard, 2021, In: Reproduction. 161, 5, p. 561-572 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology
Björndahl, L., Barratt, C. L. R., Mortimer, D., Agarwal, A., Aitken, R. J., Alvarez, J. G., Aneck-Hahn, N., Arver, S., Baldi, E., Bassas, L., Boitrelle, F., Bornman, R., Carrell, D. T., Castilla, J. A., Cerezo Parra, G., Check, J. H., Cuasnicu, P. S., Darney, S. P., de Jager, C., De Jonge, C. J. & 67 others, , 2022, In: Human Reproduction. 37, 11, p. 2497-2502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
Jensen, Martin Blomberg, Leffers, H., Petersen, Jørgen Holm, Daugaard, G., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 2008, In: Annals of Oncology. 19, 11, p. 1910-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract
Jensen, Martin Blomberg, Nielsen, J. E., Jørgensen, A., Rajpert-De Meyts, E., Kristensen, D. M., Jørgensen, N., Skakkebæk, Niels Erik, Juul, Anders & Leffers, H., 1 May 2010, In: Human Reproduction. 25, 5, p. 1303-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone
Blum, W. F., Englaro, P., Hanitsch, S., Juul, Anders, Hertel, N., Müller, J., Skakkebæk, Niels Erik, Heiman, M. L., Birkett, M., Attanasio, A. M., Kiess, W. & Rascher, W., 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 9, p. 2904-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth
Boas, M., Frederiksen, H., Feldt-Rasmussen, Ulla, Skakkebæk, Niels Erik, Hegedüs, L., Hilsted, L. M., Juul, Anders & Main, Katharina Maria, 1 Oct 2010, In: Environmental Health Perspectives. 118, 10, p. 1458-64 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Year of birth and sperm count in 10 Danish occupational studies
Bonde, Jens Peter, Jensen, T. K., Larsen, S. B., Abell, A., Scheike, Thomas, Hjøllund, N. H. I., Kolstad, H. A., Ernst, E., Giwercman, A., Skakkebæk, Niels Erik, Keiding, N. & Olsen, J., 1998, In: Scandinavian Journal of Work, Environment & Health. 24, 5, p. 407-413 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals
Brenker, C., Rehfeld, Anders Aagaard, Schiffer, C., Kierzek, M., Kaupp, U. B., Skakkebæk, Niels Erik & Strünker, T., 2018, In: Human Reproduction. 33, 10, p. 1915-1923 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The association between in-utero exposure to stressful life events during pregnancy and male reproductive function in a cohort of 20-year-old offspring: The Raine Study
Bräuner, E. V., Hansen, Åse Marie, Doherty, D. A., Dickinson, J. E., Handelsman, D. J., Hickey, M., Skakkebæk, Niels Erik, Juul, A. & Hart, R., 8 Jul 2019, In: Human reproduction (Oxford, England). 34, 7, p. 1345-1355 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endocrine Disrupting Chemicals and Risk of Testicular Cancer A Systematic Review and Meta-analysis
Bräuner, E. V., Lim, Youn-Hee, Koch, T., Uldbjerg, C. S., Gregersen, L. S., Pedersen, M. K., Frederiksen, H., Petersen, Jørgen Holm, Coull, B. A., Andersson, A., Hickey, M., Skakkebæk, Niels Erik, Hauser, R. & Juul, Anders, 2021, In: The Journal of clinical endocrinology and metabolism. 106, 12, p. e4834–e4860 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects
Hansen, Lasse Bøllehuus, Kaludjerovic, J., Nielsen, J. E., Rehfeld, Anders Aagaard, Poulsen, N. N., Ide, N., Skakkebæk, Niels Erik, Frederiksen, H., Juul, Anders, Lanske, B. & Jensen, M. B., 2020, In: F A S E B Journal. 34, 9, p. 12436-12449Research output: Contribution to journal › Journal article › Research › peer-review
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Behandling og udredning af mandlig infertilitet og hypogonadisme
Carlsen, E., Jørgensen, N., Juul, Anders & Skakkebæk, Niels Erik, 2005, In: Maanedsskrift for Praktisk Laegegerning. 83, p. 1239-49 10 p.Research output: Contribution to journal › Review › Research
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Evidence for decreasing quality of semen during past 50 years
Carlsen, E., Giwercman, A., Keiding, N. & Skakkebæk, Niels Erik, Mar 1993, In: Obstetrical & Gynecological Survey. 48, 3, p. 200-201 2 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls
Chellakooty, M., Schmidt, I. M., Haavisto, A. M., Boisen, K. A., Damgaard, I. N., Mau, C., Petersen, Jørgen Holm, Juul, Anders, Skakkebæk, Niels Erik & Main, Katharina Maria, 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 8, p. 3515-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A prospective study of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in 942 healthy infants: associations with birth weight, gender, growth velocity, and breastfeeding
Chellakooty, M., Juul, A., Boisen, K. A., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Main, K. M., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 820-826 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Longitudinal study of serum placental GH in 455 normal pregnancies: correlation to gestational age, fetal gender, and weight
Chellakooty, M., Skibsted, L., Skouby, Sven O., Andersson, A., Petersen, J. H., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2002, In: Journal of Clinical Endocrinology and Metabolism. 87, 6, p. 2734-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth
Chellakooty, M., Vangsgaard, K., Larsen, T., Scheike, T., Falck-Larsen, J., Legarth, J., Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 1, p. 384-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between organic dietary choice during pregnancy and hypospadias in offspring: a study of mothers of 306 boys operated on for hypospadias
Christensen, J. S., Asklund, C., Skakkebæk, Niels Erik, Jørgensen, N., Andersen, H. R., Jørgensen, T. M., Olsen, L. H., Høyer, A. P., Moesgaard, J., Thorup, Jørgen Mogens & Jensen, T. K., Mar 2013, In: The Journal of Urology (Italian Edition). 189, 3, p. 1077-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone treatment of non-elderly adults with GH-deficiency
Christiansen, J., Jørgensen, J., Vahn, N., Juul, Anders, Müller, J. & Skakkebæk, Niels Erik, 1995, GHRH, GH and IGF-1: Basic and clinical Advances. p. 169-175 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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The syndrome of Growth Hormone Deficiency in adulthood
Christiansen, J., Jørgensen, J., Juul, Anders, Müller, J., Skakkebæk, Niels Erik, Fisker, S. & Vahn, N., 1995, In: Journal of Clinical Endocrinology and Metabolism. p. 7-9 2 p.Research output: Contribution to journal › Journal article › Research
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Metabolic effects of long-term GH deficiency and GH replacement
Christiansen, J., Jørgensen, J., Müller, J. & Skakkebæk, Niels Erik, 2013, Clinical Issues in growth disorders: Evaluation, diagnosis and therapy. Publishing House, Ltd., Europe, p. 163-170 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Serum inhibin B, FSH, LH and testosterone levels before and after human chorionic gonadotropin stimulation in prepubertal boys with cryptorchidism
Christiansen, P., Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 2002, In: European Journal of Endocrinology. 147, 1, p. 95-101 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid function in covid-19 and the association with cytokine levels and mortality
Clausen, C. L., Rasmussen, Å. K., Johannsen, T. H., Hilsted, Linda, Skakkebæk, Niels Erik, Szecsi, P. B., Pedersen, L., Benfield, Thomas & Juul, Anders, 2021, In: Endocrine Connections. 10, 10, p. 1234-1242 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pituitary–gonadal hormones associated with respiratory failure in men and women hospitalized with COVID-19: an observational cohort study
Clausen, C. L., Johannsen, T. H., Skakkebæk, Niels Erik, Frederiksen, H., Ryrsø, C. K., Dungu, A. M., Hegelund, M. H., Faurholt-Jepsen, D., Krogh-Madsen, Rikke, Lindegaard, Birgitte, Linneberg, Allan René, Kårhus, L. L., Juul, Anders & Benfield, Thomas, 2023, In: Endocrine Connections. 12, 1, e220444.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parental occupational exposures in wood-related jobs and risk of testicular germ cell tumours in offspring in NORD-TEST a registry-based case–control study in Finland, Norway, and Sweden
Corbin, S., Togawa, K., Schüz, J., Le Cornet, C., Fervers, B., Feychting, M., Wiebert, P., Hansen, J., Dalton, Susanne Oksbjerg, Kjærheim, K., Nordby, K. C., Østrem, R. S., Skakkebæk, Niels Erik, Uuksulainen, S., Pukkala, E. & Olsson, A., 2022, In: International Archives of Occupational and Environmental Health. 95, p. 1243–1253Research output: Contribution to journal › Journal article › Research › peer-review
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Proliferation of Sertoli cells during development of the human testis assessed by stereological methods
Cortes, Dina, Müller, J. & Skakkebæk, Niels Erik, 1 Aug 1987, In: International Journal of Andrology. 10, 4, p. 589-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method
Courant, F., Aksglæde, L., Antignac, J., Monteau, F., Sørensen, K., Andersson, A., Skakkebæk, Niels Erik, Juul, Anders & Bizec, B. L., 1 Jan 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 82-92 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing
Crain, D. A., Janssen, S. J., Edwards, T. M., Heindel, J., Ho, S., Hunt, P., Iguchi, T., Juul, Anders, McLachlan, J. A., Schwartz, J., Skakkebæk, Niels Erik, Soto, A. M., Swan, S., Walker, C., Woodruff, T. K., Woodruff, T. J., Giudice, L. C. & Guillette, L. J., 2008, In: Fertility and Sterility. 90, 4, p. 911-40 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries
Damsgaard, J., Joensen, U. N., Carlsen, E., Erenpreiss, J., Jensen, M. B., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, Anders, Skakkebæk, Niels Erik & Jørgensen, N., Dec 2016, In: European Urology. 70, 6, p. 1019-1029 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to Eugenio Ventimiglia, Francesco Montorsi, and Andrea Salonia's Letter to the Editor re: Jakob Damsgaard, Ulla N. Joensen, Elisabeth Carlsen, et al. Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries. Eur Urol 2016;70:1019-29
Damsgaard, J., Joensen, Ulla Nordström, Carlsen, E., Erenpreiss, J., Jensen, M. B., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, Anders, Skakkebæk, Niels Erik & Jørgensen, N., 2017, In: European Urology. 71, 2, p. e71-e72Research output: Contribution to journal › Comment/debate › Research
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Increase in first morning voided urinary luteinizing hormone levels precedes the physical onset of puberty
Demir, A., Voutilainen, R., Juul, Anders, Dunkel, L., Alfthan, H., Skakkebæk, Niels Erik & Stenman, U. H., 1996, In: Journal of Clinical Endocrinology and Metabolism. 81, 8, p. 2963-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information
Edsgärd, D., Scheel, M., Hansen, N. T., Ralfkiaer, U., Jensen, T. S., Skakkebæk, Niels Erik, Brunak, S., Gupta, R., Rajpert-De Meyts, E. & Ottesen, A. M., 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e122-32Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer
Edsgärd, D., Dalgaard, M. D., Weinhold, N., Wesolowska-Andersen, A., Rajpert-De Meyts, E., Ottesen, A. M., Juul, Anders, Skakkebæk, Niels Erik, Skøt Jensen, T., Gupta, R., Leffers, H. & Brunak, S., 2013, In: Frontiers in Endocrinology. 4, p. 2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Validation of image cytometry for sperm concentration measurement: Comparison with manual counting of 4010 human semen samples
Egeberg Palme, D. L., Johannsen, T. H., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Almstrup, Kristian, 2017, In: Clinica Chimica Acta. 468, p. 114-119 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status
Egeberg Palme, D. L., Rehfeld, Anders Aagaard, Bang, A. K., Nikolova, K. A., Kjærulff, S., Petersen, M. R., Jeppesen, J. V., Glensbjerg, M., Juul, Anders, Skakkebæk, Niels Erik, Ziebe, S., Jørgensen, N. & Almstrup, Kristian, 2018, In: Human Reproduction. 33, 3, p. 361-371 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The relationship between anogenital distance and reproductive hormone levels in adult men
Eisenberg, M. L., Jensen, T. K., Walters, R. C., Skakkebæk, Niels Erik & Lipshultz, L. I., 2012, In: The Journal of Urology. 187, 2, p. 594-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies
Ekbom, P., Damm, Peter, Andersson, A., Skakkebæk, Niels Erik, Feldt-Rasmussen, Ulla & Mathiesen, Elisabeth, 1 Jan 2006, In: Acta Obstetricia et Gynecologica Scandinavica. 85, 2, p. 143-7 5 p.Research output: Contribution to journal › Journal article › Research
- Published
Role of environmental factors in the timing of puberty
Euling, S. Y., Selevan, S. G., Pescovitz, O. H. & Skakkebæk, Niels Erik, 2008, In: Pediatrics. 121 Suppl 3, p. S167-S171Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Semen quality and reproductive hormone levels in men from Southern Spain
Fernandez, M. F., Duran, I., Olea, N., Avivar, C., Vierula, M., Toppari, J., Skakkebæk, Niels Erik & Jørgensen, N., 2012, In: International Journal of Andrology. 35, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The growth hormone (GH)-insulin-like growth factor axis during testosterone replacement therapy in GH-treated hypopituitary males
Fisker, S., Nørrelund, H., Juul, Anders, Skakkebæk, Niels Erik, Christiansen, J. S. & Jørgensen, J. O., 2001, In: Growth Hormone & I G F Research. 11, 2, p. 104-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex differences in the vaccine-specific and non-targeted effects of vaccines
Flanagan, K. L., Klein, S. L., Skakkebæk, Niels Erik, Marriott, I., Marchant, A., Selin, L., Fish, E. N., Prentice, A. M., Whittle, H., Benn, C. S. & Aaby, P., 16 Mar 2011, In: Vaccine. 29, 13, p. 2349-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV filters in matched seminal fluid-, urine-, and serum samples from young men
Frederiksen, H., Krause, M., Jørgensen, N., Rehfeld, Anders Aagaard, Skakkebæk, Niels Erik & Andersson, A., 2021, In: Journal of Exposure Science and Environmental Epidemiology. 31, p. 345–355Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men: 2009–2017
Frederiksen, H., Nielsen, O., Koch, H. M., Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Andersson, A. M., Jan 2020, In: International Journal of Hygiene and Environmental Health. 223, 1, p. 93-105Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human urinary excretion of non-persistent environmental chemicals: an overview of Danish data collected between 2006 and 2012
Frederiksen, H., Jensen, T. K., Jørgensen, N., Kyhl, H. B., Husby, S., Skakkebæk, Niels Erik, Main, Katharina Maria, Juul, Anders & Andersson, A., 2014, In: Reproduction. 147, 4, p. 555-565 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents
Frederiksen, H., Nielsen, O., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A., Mar 2017, In: International Journal of Hygiene and Environmental Health. 220, 2, Part A, p. 244-253 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35319116
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
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Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
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