Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method

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Estrogens and androgens play key roles for pubertal onset and sexual maturation. Most currently used immunoassays are not sensitive enough to accurately measure the low circulating levels of sex steroids in children without any signs of puberty. However, this does not exclude that sex steroids have important biological roles in prepubertal children.
Original languageEnglish
JournalJournal of Clinical Endocrinology and Metabolism
Volume95
Issue number1
Pages (from-to)82-92
Number of pages11
ISSN0021-972X
DOIs
Publication statusPublished - 1 Jan 2010

ID: 34048011