Niels Erik Skakkebæk
Affiliate Professor
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Anogenital distance as a phenotypic signature through infancy
Priskorn, L., Petersen, Jørgen Holm, Jørgensen, N., Kyhl, H. B., Andersen, M. S., Main, Katharina Maria, Andersson, A., Skakkebæk, Niels Erik & Jensen, T. K., 2018, In: Pediatric Research. 83, 3, p. 573-579 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Familial resemblance in markers of testicular function in fathers and their young sons: a cross-sectional study
Priskorn, L., Joensen, Ulla Nordström, Petersen, Jørgen Holm, Jensen, T. K., Skakkebæk, Niels Erik & Jørgensen, N., 2021, In: Human reproduction (Oxford, England). 36, 3, p. 543-550 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adverse trends in male reproductive health and decreasing fertility rates
Priskorn, L., Holmboe, S., Jørgensen, N., Andersson, A., Almstrup, Kristian, Toppari, J. & Skakkebæk, Niels Erik, 2012, In: Animal Reproduction Science. 31, 2, p. 760-771 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is Sedentary Lifestyle Associated With Testicular Function? A Cross-Sectional Study of 1,210 Men
Priskorn, L., Jensen, T. K., Bang, A. K., Nordkap, L., Joensen, Ulla Nordström, Lassen, T. H., Olesen, I. A., Swan, S. H., Skakkebæk, Niels Erik & Jørgensen, N., 15 Aug 2016, In: American Journal of Epidemiology. 184, 4, p. 284-294 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High maternal age at first and subsequent child births in Denmark in the mid-1800s-Letter to the editor
Priskorn, L., Dahl, C. L., Pihl, A. S., Skakkebæk, Niels Erik & Juul, Anders, Oct 2019, In: European Journal of Obstetrics & Gynecology and Reproductive Biology. 241, p. 137-138 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Increasing trends in childlessness in recent birth cohorts - a registry-based study of the total Danish male population born from 1945 to 1980
Priskorn, L., Holmboe, S., Jacobsen, R., Jensen, T. K., Lassen, T. H. & Skakkebæk, Niels Erik, 2012, In: International Journal of Andrology. 35, 3, p. 449-55 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Semen quality of young men in Switzerland: a nationwide cross-sectional population-based study
Rahban, R., Priskorn, L., Senn, A., Stettler, E., Galli, F., Vargas, J., Van den Bergh, M., Fusconi, A., Garlantezec, R., Jensen, T. K., Multigner, L., Skakkebæk, Niels Erik, Germond, M., Jørgensen, N., Nef, S. & The NICER Working Group, T. N. W. G., 2019, In: Andrology. 7, 6, p. 818-826Research output: Contribution to journal › Journal article › Research › peer-review
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The antidepressant Sertraline inhibits CatSper Ca2+channels in human sperm
Rahban, R., Rehfeld, Anders Aagaard, Schiffer, C., Brenker, C., Egeberg Palme, D. L., Wang, T., Lorenz, J., Almstrup, Kristian, Skakkebæk, Niels Erik, Strünker, T. & Nef, S., 2021, In: Human Reproduction. 36, 10, p. 2638-2648Research output: Contribution to journal › Journal article › Research › peer-review
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Increasing international efforts to understand and conquer testicular germ cell cancer
Rajpert-De Meyts, E., Daugaard, G., Almstrup, Kristian, Jørgensen, A., Rørth, M., Jørgensen, N., von der Maase, H. & Skakkebæk, Niels Erik, Jan 2015, In: Andrology. 3, 1, p. 1-3 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation
Rajpert-De Meyts, E., Poll, S. N., Goukasian, I., Jeanneau, C., Herlihy, A. S., Bennett, Eric Paul, Skakkebæk, Niels Erik, Clausen, Henrik, Giwercman, A. & Mandel, Ulla, 2007, In: Virchows Archiv. 451, 4, p. 805-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Goodbye International Journal of Andrology, welcome Andrology!
Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2022, In: Andrology. 10, S2, p. 133-138Research output: Contribution to journal › Editorial › Research › peer-review
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Prolonged expression of the c-kit receptor in germ cells of intersex fetal testes
Rajpert-De Meyts, E., Jørgensen, N., Müller, J. & Skakkebæk, Niels Erik, 1 Feb 1996, In: Journal of Pathology. 178, 2, p. 166-9 4 p.Research output: Contribution to journal › Journal article › Research
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The testis in childhood between birth and puberty
Rajpert-De Meyts, E., Almstrup, H. K. & Skakkebæk, Niels Erik, 2012, Atlas on the Human Testis: Normal Morphology and Pathology. p. 69-75 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Goodbye International Journal of Andrology, welcome Andrology!
Rajpert-De Meyts, E., Eliasson, R., Comhaire, F. H., Skakkebæk, Niels Erik, Sharpe, R. M. & Toppari, J., 2012, In: International Journal of Andrology. 36, 6, p. 769-774 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathogenesis of testicular carcinoma in situ and germ cell cancer: still more questions than answers
Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e2-6Research output: Contribution to journal › Journal article › Research › peer-review
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Optimised detection of germ cell neoplasia in situ in contralateral biopsy reduces the risk of second testis cancer
Rajpert-De Meyts, E., Jørgensen, N., Petersen, Jørgen Holm, Almstrup, Kristian, Aksglaede, L., Lauritsen, J., Rørth, M., Daugaard, G. & Skakkebæk, Niels Erik, 2022, In: BJU International. 130, 5, p. 646-654 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proceedings of the 7th Copenhagen Workshop on Testicular Carcinoma in situ and Germ Cell Cancer, 13-15 October 2010
Rajpert-De Meyts, E., Grigor, K. M. & Skakkebæk, Niels Erik, 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e1Research output: Contribution to journal › Journal article › Research
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Testicular Dysgenesis Syndrom and Carcinoma In Situ Testis
Rajpert-De Meyts, E., Almstrup, H. K. & Skakkebæk, Niels Erik, 2012, Atlas on the Human Testis. Jezek, D. (ed.). p. 159-178 19 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Testicular cancer: New inroads into early diagnosis
Rajpert-De Meyts, E., Znaor, A. & Skakkebæk, Niels Erik, 2020, World Cancer Report: Cancer Research for Cancer Prevention. Wild, C. P., Weiderpass, E. & Stewart, B. W. (eds.). IARC Press, p. 430-438 (World Cancer Reports).Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research › peer-review
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Cryptorchidism, hypospadias, testicular tumours and testicular dysgenesis syndrome
Rajpert-De Meyts, E., Main, Katharina Maria, Toppari, J. & Skakkebæk, Niels Erik, 2010, Endocrinology.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Origin of testicular germ cell neoplasia: The role of sex chromosomes
Rajpert-De Meyts, E., Ottesen, A. M., Høi-Hansen, Christina Engel, Sonne, Si Brask, Leffers, H. & Skakkebæk, Niels Erik, 1 Jan 2007, The Y Chromosome and Male Germ Cell Biology in Health and Diseases. World Scientific Publishing Co., p. 289-308 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Histopathological Evaluation of Testicular Biopsy
Rajpert-de Meyts, E., Grigor, K. M. & Skakkebæk, Niels Erik, 2017, Endocrinology of the Testis and Male Reproduction. SimoniIlpo, M. & Huhtaniemi, I. (eds.). p. 1-20 (Endocrinology of the Testis and Male Reproduction).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Massive weight loss restores 24-hour growth hormone release profiles and serum insulin-like growth factor-I levels in obese subjects
Rasmussen, M. H., Hvidberg, A., Juul, Anders, Main, Katharina Maria, Gotfredsen, A., Skakkebæk, Niels Erik, Hilsted, J. & Skakkebae, N. E., 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 4, p. 1407-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of stimulation of 24-hour growth hormone release by hypocaloric diet in obesity
Rasmussen, M. H., Juul, Anders, Kjems, L. L., Skakkebæk, Niels Erik & Hilsted, J., 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, 3, p. 796-801 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prenatal and adult exposures to smoking are associated with adverse effects on reproductive hormones, semen quality, final height and body mass index
Ravnborg, T. L., Jensen, T. K., Andersson, A., Toppari, J., Skakkebæk, Niels Erik & Jørgensen, N., 18 Feb 2011, In: Human Reproduction. 26, 5, p. 1000-1011 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism
Rehfeld, Anders Aagaard, Frederiksen, H., Rasmussen, R. H., David, A., Chaker, J., Nielsen, B. S., Nielsen, J. E., Juul, Anders, Skakkebæk, Niels Erik & Kristensen, D. M., 2022, In: Human reproduction (Oxford, England). 37, 5, p. 922-935 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemical UV Filters Mimic the Effect of Progesterone on Ca(2+) Signaling in Human Sperm Cells
Rehfeld, Anders Aagaard, Dissing, Steen & Skakkebæk, Niels Erik, Nov 2016, In: Endocrinology. 157, 11, p. 4297-4308 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bisphenol A Diglycidyl Ether (BADGE) and Bisphenol Analogs, but Not Bisphenol A (BPA), Activate the CatSper Ca2+ Channel in Human Sperm
Rehfeld, Anders Aagaard, Andersson, A. M. & Skakkebæk, Niels Erik, 2020, In: Frontiers in Endocrinology. 11, 11 p., 324.Research output: Contribution to journal › Journal article › Research › peer-review
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Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
Rehfeld, Anders Aagaard, Palme, D. L. E., Almstrup, Kristian, Juul, Anders & Skakkebæk, Niels Erik, 2019, In: Journal of Visualized Experiments. 145, p. e59212Research output: Contribution to journal › Journal article › Research › peer-review
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
Rehfeld, Anders Aagaard, Egeberg, D., Almstrup, Kristian, Petersen, Jørgen Holm, Dissing, Steen & Skakkebæk, Niels Erik, 2018, In: Endocrine Connections. 7, 1, p. 16-25Research output: Contribution to journal › Journal article › Research › peer-review
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Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
Rehfeld, A., Egeberg Palme, D. L., Almstrup, K., Juul, Anders & Skakkebæk, Niels Erik, 1 Mar 2019, In: Journal of visualized experiments : JoVE. 145, 9 p., e59212.Research output: Contribution to journal › Journal article › Research › peer-review
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Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca2+ Signals in Boar Sperm Cells
Rehfeld, Anders Aagaard, Mendoza, N., Ausejo, R. & Skakkebæk, Niels Erik, 2020, In: Frontiers in Physiology. 11, p. 785Research output: Contribution to journal › Journal article › Research › peer-review
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An update on semen quality among young Finnish men and comparison with Danish data
Rodprasert, W., Virtanen, H. E., Sadov, S., Perheentupa, A., Skakkebæk, Niels Erik, Jørgensen, N. & Toppari, J., 2019, In: Andrology. 7, 1, p. 15-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reproductive Markers of Testicular Function and Size During Puberty in Boys With and Without a History of Cryptorchidism
Rodprasert, W., Koskenniemi, J. J., Virtanen, H. E., Sadov, S., Perheentupa, A., Ollila, H., Albrethsen, J., Andersson, A., Juul, Anders, Skakkebæk, Niels Erik, Main, Katharina Maria & Toppari, J., 2022, In: The Journal of clinical endocrinology and metabolism. 107, 12, p. 3353-3361 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sperm retrieval in adolescent males with Klinefelter syndrome: medical and ethical issues
Rogol, A. D. & Skakkebæk, Niels Erik, Apr 2016, In: Translational Pediatrics. 5, 2, p. 104-106Research output: Contribution to journal › Comment/debate › Research
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Sperm Concentration, Testicular Volume and Age Predict Risk of Carcinoma In Situ in Contralateral Testis of Men with Testicular Germ Cell Cancer
Rud, C. N., Daugaard, G., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Petersen, Jørgen Holm & Jørgensen, N., 2013, In: Journal of Urology. 190, 6, p. 2074-2080 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contralateral biopsy in the management of testicular cancer: what we have learned and what we need to improve
Rørth, M., Grigor, K. M., Jørgensen, N., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., Jan 2015, In: Andrology. 3, 1, p. 99-101 3 p.Research output: Contribution to journal › Editorial › Research
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Carcinoma in situ in the testis
Rørth, M., Rajpert-De Meyts, E., Andersson, L., Dieckmann, Peter, Fosså, S. D., Grigor, K. M., Hendry, W. F., Herr, H. W., Looijenga, L. H., Oosterhuis, J. W. & Skakkebæk, Niels Erik, 2000, In: Scandinavian Journal of Urology and Nephrology, Supplementum. 205, p. 166-86 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular Growth During Puberty in Boys With and Without a History of Congenital Cryptorchidism
Sadov, S., Koskenniemi, J. J., Virtanen, H. E., Perheentupa, A., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Main, Katharina Maria & Toppari, J., Jun 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 6, p. 2570–2577 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serum testosterone levels in three-month-old boys predict their semen quality as young adults
Scheutz Henriksen, L., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Jørgensen, N., Virtanen, H. E., Priskorn, Lærke, Juul, Anders, Toppari, J. & Main, Katharina Maria, 2022, In: The Journal of clinical endocrinology and metabolism. 107, 7, p. 1965–1975 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Direct action of endocrine disrupting chemicals on human sperm
Schiffer, C., Müller, A., Egeberg, D. L., Alvarez, L., Brenker, C., Rehfeld, Anders Aagaard, Frederiksen, H., Wäschle, B., Kaupp, U. B., Balbach, M., Wachten, D., Skakkebæk, Niels Erik, Almstrup, Kristian & Strünker, T., Jul 2014, In: E M B O Reports. 15, 7, p. 758-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular germ cell cancer incidence in an immigration perspective, Denmark, 1978 to 2003
Schmiedel, S., Schüz, J., Skakkebæk, Niels Erik & Johansen, C., 1 Apr 2010, In: Journal of Urology. 183, 4, p. 1378-82 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Schmoll, H., Jordan, K., Huddart, R., Pes, M. P. L., Horwich, A., Fizazi, K., Kataja, V., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, ESMO Guidelines Working Group, E. G. W. G. & von der Maase, H. R. R., 1 May 2010, In: Annals of Oncology. 21 Suppl 5, p. v140-6Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular non-seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Schmoll, H., Jordan, K., Huddart, R., Pes, M. P. L., Horwich, A., Fizazi, K., Kataja, V., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, ESMO Guidelines Working Group, E. G. W. G. & von der Maase, H. R. R., 1 May 2010, In: Annals of Oncology. 21 Suppl 5, p. v147-54Research output: Contribution to journal › Journal article › Research › peer-review
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Serum inhibin A and inhibin B in healthy prepubertal, pubertal, and adolescent girls and adult women: relation to age, stage of puberty, menstrual cycle, follicle-stimulating hormone, luteinizing hormone, and estradiol levels
Sehested, A., Juul, Anders, Andersson, A. M., Petersen, Jørgen Holm, Jensen, T. K., Müller, J. & Skakkebæk, Niels Erik, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 4, p. 1634-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gene expression profiles of mouse spermatogenesis during recovery from irradiation
Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H., Almstrup, K., Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H. & Almstrup, Kristian, 1 Jan 2009, In: Reproductive Biology and Endocrinology. 7, p. 130Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro bioassay investigations of the endocrine disrupting potential of steviol glycosides and their metabolite steviol, components of the natural sweetener Stevia
Shannon, M., Rehfeld, Anders Aagaard, Frizzell, C., Livingstone, C., McGonagle, C., Skakkebæk, Niels Erik, Wielogórska, E. & Connolly, L., 15 May 2016, In: Molecular and Cellular Endocrinology. 427, p. 65-72Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects
Sharpe, R. M. & Skakkebæk, Niels Erik, 2008, In: Fertility and Sterility. 89, 2 Suppl, p. e33-e38Research output: Contribution to journal › Journal article › Research › peer-review
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Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland
Shen, H., Main, K. M., Andersson, A. M., Damgaard, I. N., Virtanen, H. E., Toppari, J., Schramm, K. W. & Skakkebæk, Niels Erik, 2008, In: Human Reproduction. 23, 1, p. 201-210 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations
Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Jørgensen, N., Main, Katharina Maria, Leffers, H., Andersson, A., Juul, Anders, Jensen, T. K. & Toppari, J., 2007, In: International Journal of Andrology. 30, 4, p. 198-204; discussion 204-5Research output: Contribution to journal › Review › Research
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A Brief Review of the Link between Environment and Male Reproductive Health: Lessons from Studies of Testicular Germ Cell Cancer
Skakkebæk, Niels Erik, 2016, In: Hormone Research in Paediatrics. 86, 4, p. 240-246 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Populations, decreasing fertility, and reproductive health
Skakkebæk, Niels Erik, Jørgensen, N., Andersson, A., Juul, Anders, Main, Katharina Maria, Jensen, T. K. & Toppari, J., 13 Apr 2019, In: Lancet Oncology. 393, 10180, p. 1500-1501 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility
Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Buck Louis, G. M., Toppari, J., Andersson, A., Eisenberg, M. L., Jensen, T. K., Jørgensen, N., Swan, S. H., Sapra, K. J., Ziebe, S., Priskorn, L. & Juul, Anders, Jan 2016, In: Physiological Reviews. 96, 1, p. 55-97 43 p.Research output: Contribution to journal › Review › Research › peer-review
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Normal reference ranges for semen quality and their relations to fecundity
Skakkebæk, Niels Erik, 1 Jan 2010, In: Asian Journal of Andrology. 12, 1, p. 95-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sperm counts, testicular cancers, and the environment
Skakkebæk, Niels Erik, 10 Oct 2017, In: B M J. 359, j4517.Research output: Contribution to journal › Editorial › Research
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Is human fecundity declining?
Skakkebæk, Niels Erik, Jørgensen, N., Main, Katharina Maria, Rajpert-De Meyts, E., Leffers, H., Andersson, A., Juul, Anders, Carlsen, E., Mortensen, G. K., Jensen, T. K. & Toppari, J., 1 Feb 2006, In: International Journal of Andrology. 29, 1, p. 2-11 10 p.Research output: Contribution to journal › Journal article › Research
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Commentary: sperm counts, data responsibility, and good scientific practice
Skakkebæk, Niels Erik, Andersson, A., Juul, Anders, Jensen, T. K., Almstrup, Kristian, Toppari, J. & Jørgensen, N., 1 Sep 2011, In: Epidemiology. 22, 5, p. 620-1 2 p.Research output: Contribution to journal › Letter › Research
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The exposure of fetuses and children to endocrine disrupting chemicals: a European Society for Paediatric Endocrinology (ESPE) and Pediatric Endocrine Society (PES) call to action statement
Skakkebæk, Niels Erik, Toppari, J., Söder, O., Gordon, C. M., Divall, S. & Draznin, M., 1 Oct 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 10, p. 3056-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Environmental factors in declining human fertility
Skakkebæk, Niels Erik, Lindahl-Jacobsen, R., Levine, H., Andersson, A., Jørgensen, N., Main, Katharina Maria, Lidegaard, Øjvind, Priskorn, Lærke, Holmboe, S. A., Bräuner, E. V., Almstrup, Kristian, Franca, L. R., Znaor, A., Kortenkamp, A., Hart, R. J. & Juul, Anders, 2022, In: Nature Reviews Endocrinology. 18, p. 139–157Research output: Contribution to journal › Review › Research › peer-review
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Association between testicular dysgenesis syndrome (TDS) and testicular neoplasia: evidence from 20 adult patients with signs of maldevelopment of the testis
Skakkebæk, Niels Erik, Holm, M., Hoei-Hansen, C., Jørgensen, N. & Rajpert-De Meyts, E., 1 Jan 2003, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 111, 1, p. 1-9; discussion 9-11Research output: Contribution to journal › Journal article › Research
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Changes in semen and the testis
Skakkebæk, Niels Erik & Keiding, N., 19 Nov 1994, In: BMJ. 309, 6965, p. 1316-1317 2 p.Research output: Contribution to journal › Editorial › Research
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Mere Testikelkræft og dårlig sædkvalitet
Skakkebæk, Niels Erik, 2008, In: Tidsskrift for Den norske lægeforening. 128, p. 554-554Research output: Contribution to journal › Journal article › Research › peer-review
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Selection Biases in Semen Study?
Skakkebæk, Niels Erik, Giwercman, A., Jensen, T. K., Carlsen, E., Jørgensen, N. & Keiding, N., Jun 1998, In: Fertility & Sterility. 69, 6, p. 1158-1159 2 p.Research output: Contribution to journal › Comment/debate › Research
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Time to pregnancy and semen parameters: a cross-sectional study among fertile couples from four European cities
Slama, R., Eustache, F., Ducot, B., Jensen, T. K., Jørgensen, N., Horte, A., Irvine, S., Suominen, J., Andersen, A. G., Auger, J., Vierula, M., Toppari, J., Andersen, A. N., Keiding, N., Skakkebæk, Niels Erik, Spira, A. & Jouannet, P., 2002, In: Human Reproduction. 17, 2, p. 503-515 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is human fecundity changing? A discussion of research and data gaps precluding us from having an answer
Smarr, M. M., Sapra, K. J., Gemmill, A., Kahn, L. G., Wise, L. A., Lynch, C. D., Factor-Litvak, P., Mumford, S. L., Skakkebæk, Niels Erik, Slama, R., Lobdell, D. T., Stanford, J. B., Jensen, T. K., Boyle, E. H., Eisenberg, M. L., Turek, P. J., Sundaram, R., Thoma, M. E. & Buck Louis, G. M., 2017, In: Human Reproduction. 32, 3, p. 499-504Research output: Contribution to journal › Comment/debate › Research
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Sweat secretion rates in growth hormone disorders
Sneppen, S. B., Main, Katharina Maria, Juul, Anders, Pedersen, L. M., Kristensen, L. O., Skakkebæk, Niels Erik & Feldt-Rasmussen, Ulla, 2000, In: Clinical Endocrinology. 53, 5, p. 601-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Total and free insulin-like growth factor I, insulin-like growth factor binding protein 3 and acid-labile subunit reflect clinical activity in acromegaly
Sneppen, S. B., Lange, M. W., Pedersen, L. M., Kristensen L, L. Ø., Main, Katharina Maria, Juul, Anders, Skakkebæk, Niels Erik & Feldt-Rasmussen, Ulla, 2001, In: Growth Hormone & I G F Research. 11, 6, p. 384-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leydig cell clustering and Reinke crystal distribution in relation to hormonal function in adult patients with testicular dysgenesis syndrome (TDS) including cryptorchidism
Soerensen, R. R., Johannsen, T. H., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., Oct 2016, In: Hormones. 15, 4, p. 518-526 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours
Sonne, Si Brask, Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, Kristian, Daugaard, G., Skakkebæk, Niels Erik, Leffers, H., Rajpert-De Meyts, E., Sonne, S. B., Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, K., Daugaard, G., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 114, 7-8, p. 549-58 10 p.Research output: Contribution to journal › Journal article › Research
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Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte
Sonne, Si Brask, Almstrup, Kristian, Dalgaard, M., Juncker, A. S., Edsgard, D., Ruban, L., Harrison, N. J., Schwager, C., Abdollahi, A., Huber, P. E., Brunak, Søren, Gjerdrum, L. M., Moore, H. D., Andrews, P. W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jun 2009, In: Current Cancer Research. 69, 12, p. 5241-50 10 p.Research output: Contribution to journal › Journal article › Research
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Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours
Sonne, Si Brask, Herlihy, A. S., Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, Kristian, Skakkebæk, Niels Erik, Marks, A., Leffers, H. & Rajpert-De Meyts, E., 2006, In: Virchows Archiv. 449, 2, p. 200-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular dysgenesis syndrome and the origin of carcinoma in situ testis
Sonne, Si Brask, Kristensen, D. M., Novotny, G. W., Olesen, I. A., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 2008, In: International Journal of Andrology. 31, 2, p. 275-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Do environmental factors play a role in the aetiology of carcinoma in situ testis and the testicular dysgenesis syndrome?
Sonne, Si Brask, Hoei-Hansen, C. E., Fisher, J. S., Leffers, H., Rajpert-de Meyts, E. & Skakkebæk, Niels Erik, 2004, In: Verhandlungen der Deutschen Gesellschaft fur Pathologie. 88, p. 144-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Testicular function in young men in long-term remission after treatment for the early stages of Hodgkin's disease
Specht, Lena, Geisler, C., Hansen, M. M. & Skakkebæk, Niels Erik, 1 Oct 1984, In: Scandinavian journal of haematology. 33, 4, p. 356-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum sex hormone-binding globulin levels in healthy children and girls with precocious puberty before and during gonadotropin-releasing hormone agonist treatment
Sørensen, K., Andersson, A. M., Skakkebæk, Niels Erik & Juul, Anders, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 3189-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the Leydig cell compartment in testicular biopsies and association with biochemical Leydig cell dysfunction in testicular cancer survivors
Tarsitano, M. G., Bandak, M., Jørgensen, N., Skakkebæk, Niels Erik, Juul, Anders, Lenzi, A., Daugaard, G. & Rajpert-De Meyts, E., 2018, In: Andrology. 6, 5, p. 748-755 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypothesis: Metformin is a potential reproductive toxicant
Tavlo, M., Skakkebæk, Niels Erik, Mathiesen, Elisabeth, Kristensen, D. M., Kjær, Kurt H., Andersson, A. & Lindahl-Jacobsen, R., 2022, In: Frontiers in Endocrinology. 13, 8 p., 1000872.Research output: Contribution to journal › Journal article › Research › peer-review
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Early puberty in internationally adopted girls: hormonal and clinical markers of puberty in 276 girls examined biannually over two years
Teilmann, Grete Katrine, Petersen, Jørgen Holm, Gormsen, M., Damgaard, K., Skakkebæk, Niels Erik, Jensen, T. K., Teilmann, Grete Katrine, Petersen, J. H., Gormsen, M., Damgaard, K., Skakkebæk, Niels Erik & Jensen, T. K., 1 Jan 2009, In: Hormone Research. 72, 4, p. 236-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries
Teilmann, Grete Katrine, Pedersen, C., Jensen, T. K., Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Pediatrics. 116, 6, p. 1323-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Putative effects of endocrine disrupters on pubertal development in the human
Teilmann, Grete Katrine, Juul, Anders, Skakkebæk, Niels Erik & Toppari, J., 2002, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 16, 1, p. 105-21 17 p.Research output: Contribution to journal › Journal article › Research
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Intranasal LH-RH treatment of cryptorchidism. A clinical trial and 5 years follow-up
Thorup, Jørgen Mogens, Mauritzen, K. & Skakkebæk, Niels Erik, 1987, In: European Journal of Pediatrics. 146 Suppl 2, p. S40-1Research output: Contribution to journal › Journal article › Research › peer-review
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Re: The true incidence of cryptorchidism in Denmark: D. Cortes, E. M. Kjellberg, M. Breddam and J. Thorup, J Urol 2008; 179: 314-318
Thorup, Jørgen Mogens, Cortes, Dina, Main, Katharina Maria, Skakkebæk, Niels Erik & Toppari, J., Feb 2009, In: The Journal of Urology. 181, 2, p. 922-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prenatal pesticide exposure and PON1 genotype associated with adolescent body fat distribution evaluated by dual X-ray absorptiometry (DXA)
Tinggaard, J., Wohlfahrt-Veje, C., Husby, S., Christiansen, L., Skakkebæk, Niels Erik, Jensen, T. K., Grandjean, P., Main, Katharina Maria & Andersen, H. R., Jul 2016, In: Andrology. 4, 4, p. 735-744 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Parental Occupational Exposure to Heavy Metals and Welding Fumes and Risk of Testicular Germ Cell Tumors in Offspring: A Registry-Based Case-Control Study
Togawa, K., Le Cornet, C., Feychting, M., Tynes, T., Pukkala, E., Hansen, J., Olsson, A., Dalton, S. O., Nordby, K., Uuksulainen, S., Wiebert, P., Woldbæk, T., Skakkebæk, Niels Erik, Fervers, B. & Schüz, J., Oct 2016, In: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 25, 10, p. 1426-1434 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Male reproductive health and environmental xenoestrogens
Toppari, J., Larsen, J. C., Christiansen, P., Giwercman, A., Grandjean, P., Guillette, L. J., Jégou, B., Jensen, T. K., Jouannet, P., Keiding, N., Leffers, H., McLachlan, J. A., Meyer, O., Müller, J., Rajpert-De Meyts, E., Scheike, T., Sharpe, R., Sumpter, J. & Skakkebæk, Niels Erik, 1 Aug 1996, In: Environmental Health Perspectives. 104 Suppl 4, p. 741-803 63 p.Research output: Contribution to journal › Journal article › Research
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Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection
Toppari, J., Virtanen, H. E., Main, Katharina Maria & Skakkebæk, Niels Erik, 1 Oct 2010, In: Birth Defects Research. Part A: Clinical and Molecular Teratology. 88, 10, p. 910-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Possible developmental early effects of endocrine disrupters on child health
Toppari, J., Adamsson, A., Boas, M., Juul, Anders, Main, Katharina Maria, Skakkebæk, Niels Erik & Virtanen, H., 2012, WHO report 2012. p. 1-83Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis
Trasande, L., Zoeller, R. T., Hass, U., Kortenkamp, A., Grandjean, P., Myers, J. P., DiGangi, J., Hunt, P. M., Rudel, R., Sathyanarayana, S., Bellanger, M., Hauser, R., Legler, J., Skakkebæk, Niels Erik & Heindel, J. J., Jul 2016, In: Andrology. 4, 4, p. 565-572 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Levels of persistent organic pollutants in breast milk samples representing Finnish and Danish boys with and without hypospadias
Tysman, M., Toppari, J., Main, Katharina Maria, Adamsson, A., Wohlfahrt-Veje, C., Antignac, J., Le Bizec, B., Löyttyniemi, E., Skakkebæk, Niels Erik & Virtanen, H. E., 2023, In: Chemosphere. 313, 8 p., 137343.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Smaller genitals at school age in boys whose mothers were exposed to non-persistent pesticides in early pregnancy
Veje, C. W., Andersen, H. R., Jensen, T. K., Grandjean, P., Skakkebæk, Niels Erik & Main, Katharina Maria, 2012, In: International Journal of Andrology. 35, 3, p. 265-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early breast development in girls after prenatal exposure to non-persistent pesticides
Veje, C. W., Andersen, H. R., Schmidt, I. M., Aksglaede, L., Sørensen, K., Juul, Anders, Jensen, T. K., Grandjean, P., Skakkebæk, Niels Erik & Main, Katharina Maria, 2012, In: International Journal of Andrology. 35, 3, p. 273-82Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between congenital cryptorchidism in newborn boys and levels of dioxins and PCBs in placenta
Virtanen, H. E., Koskenniemi, J. J., Sundqvist, E., Main, Katharina Maria, Kiviranta, H., Tuomisto, J. T., Tuomisto, J., Viluksela, M., Vartiainen, T., Skakkebæk, Niels Erik & Toppari, J., 2012, In: International Journal of Andrology. 35, 3, p. 283-93 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development and descent of the testis in relation to cryptorchidism
Virtanen, H. E., Cortes, Dina, Rajpert-De Meyts, E., Ritzén, E. M., Nordenskjöld, A., Skakkebæk, Niels Erik & Toppari, J., 1 May 2007, In: Acta Paediatrica. 96, 5, p. 622-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nervous system drugs taken by future fathers and birth defects in offspring: a prospective registry-based cohort study
Wensink, M., Lu, Y., Tian, L., Jensen, T. K., Skakkebæk, Niels Erik, Lindahl-Jacobsen, R. & Eisenberg, M., 2022, In: BMJ Open. 12, 3, 8 p., e053946.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study
Wensink, M. J., Lu, Y., Tian, L., Shaw, G. M., Rizzi, S., Jensen, T. K., Mathiesen, Elisabeth, Skakkebæk, Niels Erik, Lindahl-Jacobsen, R. & Eisenberg, M. L., 2022, In: Annals of Internal Medicine. 175, 5, p. 665-673 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells
Winge, S. B., Dalgaard, M. D., Belling, K. G., Jensen, J. M., Nielsen, J. E., Aksglaede, L., Schierup, M. H., Brunak, Søren, Skakkebæk, Niels Erik, Juul, Anders, Rajpert-De Meyts, E. & Almstrup, Kristian, 2018, In: Cell Death & Disease. 9, 6, 14 p., 586.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular dysgenesis syndrome: foetal origin of adult reproductive problems
Wohlfahrt-Veje, C., Main, Katharina Maria & Skakkebæk, Niels Erik, 2009, In: Clinical Endocrinology. 71, 4, p. 459-65 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polychlorinated dibenzo-p-dioxins, furans, and biphenyls (PCDDs/PCDFs and PCBs) in breast milk and early childhood growth and IGF1
Wohlfahrt-Veje, C., Audouze, K., Brunak, Søren, Antignac, J. P., le Bizec, B., Juul, Anders, Skakkebæk, Niels Erik & Main, Katharina Maria, 2014, In: Reproduction. 147, 4, p. 391-399 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquired cryptorchidism is frequent in infancy and childhood
Wohlfahrt-Veje, C., Boisen, K. A., Boas, M., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Chellakooty, M., Suomi, A., Toppari, J., Skakkebæk, Niels Erik & Main, Katharina Maria, 2009, In: International Journal of Andrology. 32, 4, p. 423-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pubertal Onset in Boys and Girls Is Influenced by Pubertal Timing of Both Parents
Wohlfahrt-Veje, C., Mouritsen, A., Hagen, C. P., Tinggaard, J., Mieritz, M. G., Boas, M., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Main, Katharina Maria, Jul 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 7, p. 2667–2674 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35319116
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
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Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
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