Niels Erik Skakkebæk
Affiliate Professor
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Science and policy on endocrine disrupters must not be mixed: a reply to a “common sense” intervention by toxicology journal editors
Bergman, Å., Andersson, A-M., Becher, G., van den Berg, M., Blumberg, B., Bjerregaard, P., Bornehag, C-G., Bornman, R., Brandt, I., Brian, J. V., Casey, S. C., Fowler, P. A., Frouin, H., Giudice, L. C., Iguchi, T., Hass, U., Jobling, S., Juul, A., Kidd, K. A., Kortenkamp, A. & 21 others, , 2013, In: Environmental Health. 12, 69, p. 1-4 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Germ cell neoplasia in situ (GCNIS): evolution of the current nomenclature for testicular pre-invasive germ cell malignancy
Berney, D. M., Looijenga, L. H. J., Idrees, M., Oosterhuis, J. W., Rajpert-De Meyts, E., Ulbright, T. M. & Skakkebæk, Niels Erik, Jul 2016, In: Histopathology. 69, 1, p. 7-10 4 p.Research output: Contribution to journal › Review › Research › peer-review
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Intranasalt gonadotropinfrigørende hormon (LH-RH) som behandling ved retentio testis
Bertelsen, A., Skakkebæk, Niels Erik, Mauritzen, K., Preuss, P., Pedersen, P. V. & Thorup, Jørgen Mogens, 15 Jun 1981, In: Ugeskrift for Laeger. 143, 25, p. 1595-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening for carcinoma in situ of the contralateral testis in patients with germinal testicular cancer
Berthelsen, Jens, Skakkebæk, Niels Erik, von der Maase, H., Sørensen, B. L. & Mogensen, P., 1982, In: British medical journal (Clinical research ed.). 285, 6356, p. 1683-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro investigation of endocrine disrupting effects of pesticides on Ca2+-signaling in human sperm cells through actions on the sperm-specific and steroid-activated CatSper Ca2+-channel
Birch, Michala Rosa, Johansen, M., Skakkebæk, Niels Erik, Andersson, A. & Rehfeld, Anders Aagaard, 2022, In: Environment International. 167, 15 p., 107399.Research output: Contribution to journal › Journal article › Research › peer-review
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Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm
Birch, M. R., Dissing, Steen, Skakkebæk, Niels Erik & Rehfeld, Anders Aagaard, 2021, In: Reproduction. 161, 5, p. 561-572 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology
Björndahl, L., Barratt, C. L. R., Mortimer, D., Agarwal, A., Aitken, R. J., Alvarez, J. G., Aneck-Hahn, N., Arver, S., Baldi, E., Bassas, L., Boitrelle, F., Bornman, R., Carrell, D. T., Castilla, J. A., Cerezo Parra, G., Check, J. H., Cuasnicu, P. S., Darney, S. P., de Jager, C., De Jonge, C. J. & 67 others, , 2022, In: Human Reproduction. 37, 11, p. 2497-2502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
Jensen, Martin Blomberg, Leffers, H., Petersen, Jørgen Holm, Daugaard, G., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 2008, In: Annals of Oncology. 19, 11, p. 1910-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract
Jensen, Martin Blomberg, Nielsen, J. E., Jørgensen, A., Rajpert-De Meyts, E., Kristensen, D. M., Jørgensen, N., Skakkebæk, Niels Erik, Juul, Anders & Leffers, H., 1 May 2010, In: Human Reproduction. 25, 5, p. 1303-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone
Blum, W. F., Englaro, P., Hanitsch, S., Juul, Anders, Hertel, N., Müller, J., Skakkebæk, Niels Erik, Heiman, M. L., Birkett, M., Attanasio, A. M., Kiess, W. & Rascher, W., 1997, In: Journal of Clinical Endocrinology and Metabolism. 82, 9, p. 2904-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth
Boas, M., Frederiksen, H., Feldt-Rasmussen, Ulla, Skakkebæk, Niels Erik, Hegedüs, L., Hilsted, L. M., Juul, Anders & Main, Katharina Maria, 1 Oct 2010, In: Environmental Health Perspectives. 118, 10, p. 1458-64 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Year of birth and sperm count in 10 Danish occupational studies
Bonde, Jens Peter, Jensen, T. K., Larsen, S. B., Abell, A., Scheike, Thomas, Hjøllund, N. H. I., Kolstad, H. A., Ernst, E., Giwercman, A., Skakkebæk, Niels Erik, Keiding, N. & Olsen, J., 1998, In: Scandinavian Journal of Work, Environment & Health. 24, 5, p. 407-413 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals
Brenker, C., Rehfeld, Anders Aagaard, Schiffer, C., Kierzek, M., Kaupp, U. B., Skakkebæk, Niels Erik & Strünker, T., 2018, In: Human Reproduction. 33, 10, p. 1915-1923 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The association between in-utero exposure to stressful life events during pregnancy and male reproductive function in a cohort of 20-year-old offspring: The Raine Study
Bräuner, E. V., Hansen, Åse Marie, Doherty, D. A., Dickinson, J. E., Handelsman, D. J., Hickey, M., Skakkebæk, Niels Erik, Juul, A. & Hart, R., 8 Jul 2019, In: Human reproduction (Oxford, England). 34, 7, p. 1345-1355 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endocrine Disrupting Chemicals and Risk of Testicular Cancer A Systematic Review and Meta-analysis
Bräuner, E. V., Lim, Youn-Hee, Koch, T., Uldbjerg, C. S., Gregersen, L. S., Pedersen, M. K., Frederiksen, H., Petersen, Jørgen Holm, Coull, B. A., Andersson, A., Hickey, M., Skakkebæk, Niels Erik, Hauser, R. & Juul, Anders, 2021, In: The Journal of clinical endocrinology and metabolism. 106, 12, p. e4834–e4860 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of FGF23 and Klotho on male reproduction: Systemic vs direct effects
Hansen, Lasse Bøllehuus, Kaludjerovic, J., Nielsen, J. E., Rehfeld, Anders Aagaard, Poulsen, N. N., Ide, N., Skakkebæk, Niels Erik, Frederiksen, H., Juul, Anders, Lanske, B. & Jensen, M. B., 2020, In: F A S E B Journal. 34, 9, p. 12436-12449Research output: Contribution to journal › Journal article › Research › peer-review
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Behandling og udredning af mandlig infertilitet og hypogonadisme
Carlsen, E., Jørgensen, N., Juul, Anders & Skakkebæk, Niels Erik, 2005, In: Maanedsskrift for Praktisk Laegegerning. 83, p. 1239-49 10 p.Research output: Contribution to journal › Review › Research
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Evidence for decreasing quality of semen during past 50 years
Carlsen, E., Giwercman, A., Keiding, N. & Skakkebæk, Niels Erik, Mar 1993, In: Obstetrical & Gynecological Survey. 48, 3, p. 200-201 2 p.Research output: Contribution to journal › Review › Research › peer-review
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Inhibin A, inhibin B, follicle-stimulating hormone, luteinizing hormone, estradiol, and sex hormone-binding globulin levels in 473 healthy infant girls
Chellakooty, M., Schmidt, I. M., Haavisto, A. M., Boisen, K. A., Damgaard, I. N., Mau, C., Petersen, Jørgen Holm, Juul, Anders, Skakkebæk, Niels Erik & Main, Katharina Maria, 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 8, p. 3515-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A prospective study of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in 942 healthy infants: associations with birth weight, gender, growth velocity, and breastfeeding
Chellakooty, M., Juul, A., Boisen, K. A., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Main, K. M., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 820-826 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Longitudinal study of serum placental GH in 455 normal pregnancies: correlation to gestational age, fetal gender, and weight
Chellakooty, M., Skibsted, L., Skouby, Sven O., Andersson, A., Petersen, J. H., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2002, In: Journal of Clinical Endocrinology and Metabolism. 87, 6, p. 2734-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth
Chellakooty, M., Vangsgaard, K., Larsen, T., Scheike, T., Falck-Larsen, J., Legarth, J., Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 1, p. 384-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association between organic dietary choice during pregnancy and hypospadias in offspring: a study of mothers of 306 boys operated on for hypospadias
Christensen, J. S., Asklund, C., Skakkebæk, Niels Erik, Jørgensen, N., Andersen, H. R., Jørgensen, T. M., Olsen, L. H., Høyer, A. P., Moesgaard, J., Thorup, Jørgen Mogens & Jensen, T. K., Mar 2013, In: The Journal of Urology (Italian Edition). 189, 3, p. 1077-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth hormone treatment of non-elderly adults with GH-deficiency
Christiansen, J., Jørgensen, J., Vahn, N., Juul, Anders, Müller, J. & Skakkebæk, Niels Erik, 1995, GHRH, GH and IGF-1: Basic and clinical Advances. p. 169-175 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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The syndrome of Growth Hormone Deficiency in adulthood
Christiansen, J., Jørgensen, J., Juul, Anders, Müller, J., Skakkebæk, Niels Erik, Fisker, S. & Vahn, N., 1995, In: Journal of Clinical Endocrinology and Metabolism. p. 7-9 2 p.Research output: Contribution to journal › Journal article › Research
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Metabolic effects of long-term GH deficiency and GH replacement
Christiansen, J., Jørgensen, J., Müller, J. & Skakkebæk, Niels Erik, 2013, Clinical Issues in growth disorders: Evaluation, diagnosis and therapy. Publishing House, Ltd., Europe, p. 163-170 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Serum inhibin B, FSH, LH and testosterone levels before and after human chorionic gonadotropin stimulation in prepubertal boys with cryptorchidism
Christiansen, P., Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 2002, In: European Journal of Endocrinology. 147, 1, p. 95-101 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Thyroid function in covid-19 and the association with cytokine levels and mortality
Clausen, C. L., Rasmussen, Å. K., Johannsen, T. H., Hilsted, Linda, Skakkebæk, Niels Erik, Szecsi, P. B., Pedersen, L., Benfield, Thomas & Juul, Anders, 2021, In: Endocrine Connections. 10, 10, p. 1234-1242 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pituitary–gonadal hormones associated with respiratory failure in men and women hospitalized with COVID-19: an observational cohort study
Clausen, C. L., Johannsen, T. H., Skakkebæk, Niels Erik, Frederiksen, H., Ryrsø, C. K., Dungu, A. M., Hegelund, M. H., Faurholt-Jepsen, D., Krogh-Madsen, Rikke, Lindegaard, Birgitte, Linneberg, Allan René, Kårhus, L. L., Juul, Anders & Benfield, Thomas, 2023, In: Endocrine Connections. 12, 1, e220444.Research output: Contribution to journal › Journal article › Research › peer-review
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Parental occupational exposures in wood-related jobs and risk of testicular germ cell tumours in offspring in NORD-TEST a registry-based case–control study in Finland, Norway, and Sweden
Corbin, S., Togawa, K., Schüz, J., Le Cornet, C., Fervers, B., Feychting, M., Wiebert, P., Hansen, J., Dalton, Susanne Oksbjerg, Kjærheim, K., Nordby, K. C., Østrem, R. S., Skakkebæk, Niels Erik, Uuksulainen, S., Pukkala, E. & Olsson, A., 2022, In: International Archives of Occupational and Environmental Health. 95, p. 1243–1253Research output: Contribution to journal › Journal article › Research › peer-review
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Proliferation of Sertoli cells during development of the human testis assessed by stereological methods
Cortes, Dina, Müller, J. & Skakkebæk, Niels Erik, 1 Aug 1987, In: International Journal of Andrology. 10, 4, p. 589-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method
Courant, F., Aksglæde, L., Antignac, J., Monteau, F., Sørensen, K., Andersson, A., Skakkebæk, Niels Erik, Juul, Anders & Bizec, B. L., 1 Jan 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 82-92 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing
Crain, D. A., Janssen, S. J., Edwards, T. M., Heindel, J., Ho, S., Hunt, P., Iguchi, T., Juul, Anders, McLachlan, J. A., Schwartz, J., Skakkebæk, Niels Erik, Soto, A. M., Swan, S., Walker, C., Woodruff, T. K., Woodruff, T. J., Giudice, L. C. & Guillette, L. J., 2008, In: Fertility and Sterility. 90, 4, p. 911-40 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries
Damsgaard, J., Joensen, U. N., Carlsen, E., Erenpreiss, J., Jensen, M. B., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, Anders, Skakkebæk, Niels Erik & Jørgensen, N., Dec 2016, In: European Urology. 70, 6, p. 1019-1029 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reply to Eugenio Ventimiglia, Francesco Montorsi, and Andrea Salonia's Letter to the Editor re: Jakob Damsgaard, Ulla N. Joensen, Elisabeth Carlsen, et al. Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries. Eur Urol 2016;70:1019-29
Damsgaard, J., Joensen, Ulla Nordström, Carlsen, E., Erenpreiss, J., Jensen, M. B., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, Anders, Skakkebæk, Niels Erik & Jørgensen, N., 2017, In: European Urology. 71, 2, p. e71-e72Research output: Contribution to journal › Comment/debate › Research
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Increase in first morning voided urinary luteinizing hormone levels precedes the physical onset of puberty
Demir, A., Voutilainen, R., Juul, Anders, Dunkel, L., Alfthan, H., Skakkebæk, Niels Erik & Stenman, U. H., 1996, In: Journal of Clinical Endocrinology and Metabolism. 81, 8, p. 2963-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information
Edsgärd, D., Scheel, M., Hansen, N. T., Ralfkiaer, U., Jensen, T. S., Skakkebæk, Niels Erik, Brunak, S., Gupta, R., Rajpert-De Meyts, E. & Ottesen, A. M., 1 Aug 2011, In: International Journal of Andrology. 34, 4 Pt 2, p. e122-32Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide assessment of the association of rare and common copy number variations to testicular germ cell cancer
Edsgärd, D., Dalgaard, M. D., Weinhold, N., Wesolowska-Andersen, A., Rajpert-De Meyts, E., Ottesen, A. M., Juul, Anders, Skakkebæk, Niels Erik, Skøt Jensen, T., Gupta, R., Leffers, H. & Brunak, S., 2013, In: Frontiers in Endocrinology. 4, p. 2Research output: Contribution to journal › Journal article › Research › peer-review
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Validation of image cytometry for sperm concentration measurement: Comparison with manual counting of 4010 human semen samples
Egeberg Palme, D. L., Johannsen, T. H., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Almstrup, Kristian, 2017, In: Clinica Chimica Acta. 468, p. 114-119 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status
Egeberg Palme, D. L., Rehfeld, Anders Aagaard, Bang, A. K., Nikolova, K. A., Kjærulff, S., Petersen, M. R., Jeppesen, J. V., Glensbjerg, M., Juul, Anders, Skakkebæk, Niels Erik, Ziebe, S., Jørgensen, N. & Almstrup, Kristian, 2018, In: Human Reproduction. 33, 3, p. 361-371 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The relationship between anogenital distance and reproductive hormone levels in adult men
Eisenberg, M. L., Jensen, T. K., Walters, R. C., Skakkebæk, Niels Erik & Lipshultz, L. I., 2012, In: The Journal of Urology. 187, 2, p. 594-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies
Ekbom, P., Damm, Peter, Andersson, A., Skakkebæk, Niels Erik, Feldt-Rasmussen, Ulla & Mathiesen, Elisabeth, 1 Jan 2006, In: Acta Obstetricia et Gynecologica Scandinavica. 85, 2, p. 143-7 5 p.Research output: Contribution to journal › Journal article › Research
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Role of environmental factors in the timing of puberty
Euling, S. Y., Selevan, S. G., Pescovitz, O. H. & Skakkebæk, Niels Erik, 2008, In: Pediatrics. 121 Suppl 3, p. S167-S171Research output: Contribution to journal › Journal article › Research › peer-review
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Semen quality and reproductive hormone levels in men from Southern Spain
Fernandez, M. F., Duran, I., Olea, N., Avivar, C., Vierula, M., Toppari, J., Skakkebæk, Niels Erik & Jørgensen, N., 2012, In: International Journal of Andrology. 35, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The growth hormone (GH)-insulin-like growth factor axis during testosterone replacement therapy in GH-treated hypopituitary males
Fisker, S., Nørrelund, H., Juul, Anders, Skakkebæk, Niels Erik, Christiansen, J. S. & Jørgensen, J. O., 2001, In: Growth Hormone & I G F Research. 11, 2, p. 104-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sex differences in the vaccine-specific and non-targeted effects of vaccines
Flanagan, K. L., Klein, S. L., Skakkebæk, Niels Erik, Marriott, I., Marchant, A., Selin, L., Fish, E. N., Prentice, A. M., Whittle, H., Benn, C. S. & Aaby, P., 16 Mar 2011, In: Vaccine. 29, 13, p. 2349-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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UV filters in matched seminal fluid-, urine-, and serum samples from young men
Frederiksen, H., Krause, M., Jørgensen, N., Rehfeld, Anders Aagaard, Skakkebæk, Niels Erik & Andersson, A., 2021, In: Journal of Exposure Science and Environmental Epidemiology. 31, p. 345–355Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men: 2009–2017
Frederiksen, H., Nielsen, O., Koch, H. M., Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Andersson, A. M., Jan 2020, In: International Journal of Hygiene and Environmental Health. 223, 1, p. 93-105Research output: Contribution to journal › Journal article › Research › peer-review
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Human urinary excretion of non-persistent environmental chemicals: an overview of Danish data collected between 2006 and 2012
Frederiksen, H., Jensen, T. K., Jørgensen, N., Kyhl, H. B., Husby, S., Skakkebæk, Niels Erik, Main, Katharina Maria, Juul, Anders & Andersson, A., 2014, In: Reproduction. 147, 4, p. 555-565 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents
Frederiksen, H., Nielsen, O., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A., Mar 2017, In: International Journal of Hygiene and Environmental Health. 220, 2, Part A, p. 244-253 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35319116
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
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Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
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