Do environmental estrogens contribute to the decline in male reproductive health?

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Do environmental estrogens contribute to the decline in male reproductive health? / Jensen, Tina Kold; Toppari, Jorma; Keiding, Niels; Skakkebæk, Niels Erik.

In: Clinical Chemistry, Vol. 41, No. 12, 12.1995, p. 1896-1901.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Jensen, TK, Toppari, J, Keiding, N & Skakkebæk, NE 1995, 'Do environmental estrogens contribute to the decline in male reproductive health?', Clinical Chemistry, vol. 41, no. 12, pp. 1896-1901. <http://clinchem.aaccjnls.org/content/41/12/1896>

APA

Jensen, T. K., Toppari, J., Keiding, N., & Skakkebæk, N. E. (1995). Do environmental estrogens contribute to the decline in male reproductive health? Clinical Chemistry, 41(12), 1896-1901. http://clinchem.aaccjnls.org/content/41/12/1896

Vancouver

Jensen TK, Toppari J, Keiding N, Skakkebæk NE. Do environmental estrogens contribute to the decline in male reproductive health? Clinical Chemistry. 1995 Dec;41(12):1896-1901.

Author

Jensen, Tina Kold ; Toppari, Jorma ; Keiding, Niels ; Skakkebæk, Niels Erik. / Do environmental estrogens contribute to the decline in male reproductive health?. In: Clinical Chemistry. 1995 ; Vol. 41, No. 12. pp. 1896-1901.

Bibtex

@article{5bd647eec9214a2fbd2444de627991bd,
title = "Do environmental estrogens contribute to the decline in male reproductive health?",
abstract = "Several observations suggest that male reproductive health has been declining since World War II in many countries. The incidence of testicular cancer, hypospadias, and cryptorchidism has been increasing and semen quality has been decreasing, and these may have a common etiology. Treatment of several million pregnant women with the synthetic estrogen diethylstilbestrol led to an increase in these conditions among the sons of these women. These abnormalities probably arise during fetal development. The similarity between these effects and the adverse change in male reproductive development and function raised the question of whether the adverse changes are attributable to altered exposures to estrogenic and other endocrine-disrupting agents during fetal development. We speculate that alteration in exposure to estrogen in the past half-century may have caused the changes in male reproductive health.",
keywords = "cryptorchidism, diethylstilbestrol, hypospadias, sperm count, testicular cancer",
author = "Jensen, {Tina Kold} and Jorma Toppari and Niels Keiding and Skakkeb{\ae}k, {Niels Erik}",
year = "1995",
month = dec,
language = "English",
volume = "41",
pages = "1896--1901",
journal = "Clinical Chemistry",
issn = "0009-9147",
publisher = "American Association for Clinical Chemistry, Inc.",
number = "12",

}

RIS

TY - JOUR

T1 - Do environmental estrogens contribute to the decline in male reproductive health?

AU - Jensen, Tina Kold

AU - Toppari, Jorma

AU - Keiding, Niels

AU - Skakkebæk, Niels Erik

PY - 1995/12

Y1 - 1995/12

N2 - Several observations suggest that male reproductive health has been declining since World War II in many countries. The incidence of testicular cancer, hypospadias, and cryptorchidism has been increasing and semen quality has been decreasing, and these may have a common etiology. Treatment of several million pregnant women with the synthetic estrogen diethylstilbestrol led to an increase in these conditions among the sons of these women. These abnormalities probably arise during fetal development. The similarity between these effects and the adverse change in male reproductive development and function raised the question of whether the adverse changes are attributable to altered exposures to estrogenic and other endocrine-disrupting agents during fetal development. We speculate that alteration in exposure to estrogen in the past half-century may have caused the changes in male reproductive health.

AB - Several observations suggest that male reproductive health has been declining since World War II in many countries. The incidence of testicular cancer, hypospadias, and cryptorchidism has been increasing and semen quality has been decreasing, and these may have a common etiology. Treatment of several million pregnant women with the synthetic estrogen diethylstilbestrol led to an increase in these conditions among the sons of these women. These abnormalities probably arise during fetal development. The similarity between these effects and the adverse change in male reproductive development and function raised the question of whether the adverse changes are attributable to altered exposures to estrogenic and other endocrine-disrupting agents during fetal development. We speculate that alteration in exposure to estrogen in the past half-century may have caused the changes in male reproductive health.

KW - cryptorchidism

KW - diethylstilbestrol

KW - hypospadias

KW - sperm count

KW - testicular cancer

UR - http://www.scopus.com/inward/record.url?scp=0028860636&partnerID=8YFLogxK

M3 - Journal article

C2 - 7497651

AN - SCOPUS:0028860636

VL - 41

SP - 1896

EP - 1901

JO - Clinical Chemistry

JF - Clinical Chemistry

SN - 0009-9147

IS - 12

ER -

ID: 201899057