Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

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Standard

Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. / Sharpe, R.M.; Skakkebæk, Niels Erik.

In: Fertility and Sterility, Vol. 89, No. 2 Suppl, 2008, p. e33-e38.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Sharpe, RM & Skakkebæk, NE 2008, 'Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects', Fertility and Sterility, vol. 89, no. 2 Suppl, pp. e33-e38.

APA

Sharpe, R. M., & Skakkebæk, N. E. (2008). Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. Fertility and Sterility, 89(2 Suppl), e33-e38.

Vancouver

Sharpe RM, Skakkebæk NE. Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. Fertility and Sterility. 2008;89(2 Suppl):e33-e38.

Author

Sharpe, R.M. ; Skakkebæk, Niels Erik. / Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects. In: Fertility and Sterility. 2008 ; Vol. 89, No. 2 Suppl. pp. e33-e38.

Bibtex

@article{3ca29490991e11debc73000ea68e967b,
title = "Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects",
abstract = "Reproductive disorders of newborn (cryptorchidism, hypospadias) and young adult males (low sperm counts, testicular germ cell cancer) are common and/or increasing in incidence. It has been hypothesized that these disorders may comprise a testicular dysgenesis syndrome (TDS) with a common origin in fetal life. This has been supported by findings in an animal model of TDS involving fetal exposure to n(dibutyl) phthalate, as well as by new clinical studies. Recent advances in understanding from such studies have led to refinement of the TDS hypothesis, highlighting the central role that deficient androgen production/action during fetal testis development, may play in the origin of downstream disorders Udgivelsesdato: 2008/2",
author = "R.M. Sharpe and Skakkeb{\ae}k, {Niels Erik}",
year = "2008",
language = "English",
volume = "89",
pages = "e33--e38",
journal = "Sexuality, Reproduction and Menopause",
issn = "1546-2501",
publisher = "Elsevier",
number = "2 Suppl",

}

RIS

TY - JOUR

T1 - Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

AU - Sharpe, R.M.

AU - Skakkebæk, Niels Erik

PY - 2008

Y1 - 2008

N2 - Reproductive disorders of newborn (cryptorchidism, hypospadias) and young adult males (low sperm counts, testicular germ cell cancer) are common and/or increasing in incidence. It has been hypothesized that these disorders may comprise a testicular dysgenesis syndrome (TDS) with a common origin in fetal life. This has been supported by findings in an animal model of TDS involving fetal exposure to n(dibutyl) phthalate, as well as by new clinical studies. Recent advances in understanding from such studies have led to refinement of the TDS hypothesis, highlighting the central role that deficient androgen production/action during fetal testis development, may play in the origin of downstream disorders Udgivelsesdato: 2008/2

AB - Reproductive disorders of newborn (cryptorchidism, hypospadias) and young adult males (low sperm counts, testicular germ cell cancer) are common and/or increasing in incidence. It has been hypothesized that these disorders may comprise a testicular dysgenesis syndrome (TDS) with a common origin in fetal life. This has been supported by findings in an animal model of TDS involving fetal exposure to n(dibutyl) phthalate, as well as by new clinical studies. Recent advances in understanding from such studies have led to refinement of the TDS hypothesis, highlighting the central role that deficient androgen production/action during fetal testis development, may play in the origin of downstream disorders Udgivelsesdato: 2008/2

M3 - Journal article

VL - 89

SP - e33-e38

JO - Sexuality, Reproduction and Menopause

JF - Sexuality, Reproduction and Menopause

SN - 1546-2501

IS - 2 Suppl

ER -

ID: 14175290