Thomas Werge
Clinical Professor
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ADuLT: An efficient and robust time-to-event GWAS
Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Steinbach, J., Krebs, M. D., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Børglum, A. D., Musliner, K. L., Ganna, A., Schork, A. J., Mortensen, P. B., McGrath, J. J., Privé, F. & Vilhjálmsson, B. J., 2023, In: Nature Communications. 14, 12 p., 5553.Research output: Contribution to journal › Journal article › Research › peer-review
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AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
Nagy, S., Maurer, G. W., Hentze, J. L., Rose, M., Werge, Thomas & Rewitz, Kim, 2018, In: PLOS Genetics. 14, 12, e1007623.Research output: Contribution to journal › Journal article › Research › peer-review
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ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties
St Pourcain, B., Robinson, E. B., Anttila, V., Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., Zammit, S., Fisher, S. E., Neale, B. M., Anney, R. J. L., Ripke, S., Hollegaard, M. V., Werge, T., iPSYCH-SSI-Broad Autism Group, Ronald, A., Grove, J., Hougaard, D. M. & 4 others, , 2018, In: Molecular Psychiatry. 23, 2, p. 263-270Research output: Contribution to journal › Journal article › Research › peer-review
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Accounting for age of onset and family history improves power in genome-wide association studies
Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J., Privé, F. & 1 others, , 2022, In: American Journal of Human Genetics. 109, 3, p. 417-432 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Accumulation of Disadvantages Across Multiple Domains Amongst Subgroups of Children of Parents with Schizophrenia or Bipolar Disorder: Clustering Data from the Danish High Risk and Resilience Study VIA 7
Krantz, M. F., Ellersgaard, D., Andersen, K. K., Hemager, N., Christiani, C., Spang, K. S., Burton, B. K., Gregersen, M., Søndergaard, A., Greve, A., Gantriis, D. L., Ohland, J., Mortensen, P. B., Werge, T., Nudel, R., Wang, Y., Hougaard, D. M., Plessen, K. J., Bliksted, V., Jepsen, J. R. M. & 3 others, , 2022, In: Schizophrenia Bulletin Open. 3, 1, 16 p., sgac010.Research output: Contribution to journal › Journal article › Research › peer-review
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Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks
Appadurai, V., Bybjerg-Grauholm, J., Krebs, M. D., Rosengren, A., Buil, A., Ingason, A., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Delaneau, O., Werge, Thomas & Schork, A. J., 2023, In: Communications Biology . 6, 101.Research output: Contribution to journal › Journal article › Research › peer-review
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Accurate and Effective Detection of Recurrent Copy Number Variants in Large SNP Genotype Datasets
Montalbano, S., Sánchez, X. C., Vaez, M., Helenius, D., Werge, Thomas & Ingason, A., 2022, In: Current Protocols. 2, 12, 21 p., e621.Research output: Contribution to journal › Journal article › Research › peer-review
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Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression
Paksarian, D., Trabjerg, B. B., Merikangas, K. R., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Pedersen, C. B., Mortensen, P. B., Agerbo, E. & Horsdal, H. T., 2020, In: British Journal of Psychiatry. 217, 1, p. 390-396 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Advice on the genotyping of CYP2C19: comments on a recent article
Rasmussen, H. B. & Werge, Thomas, 2008, In: Pharmacogenetics and Genomics (Print Edition). 18, 7, p. 647-648 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Age at first birth in women is genetically associated with increased risk of schizophrenia
Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, , 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.Research output: Contribution to journal › Journal article › Research › peer-review
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Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome
Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Siebner, Hartwig Roman & Garrido, M. I., 2018, In: Schizophrenia Research. 197, p. 328-336Research output: Contribution to journal › Journal article › Research › peer-review
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Altered limbic microstructure in antipsychotic-naïve first-episode schizophrenia patients and associations with the schizophrenia susceptibility gene ZNF804A
Ebdrup, B., Baare, W., Hansen, T., Rasmussen, H., Aggernæs, B., Werge, Thomas, Glenthøj, Birte Yding & Skimminge, A., 2011. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies
Thompson, W. K., Wang, Y., Schork, A. J., Witoelar, A., Zuber, V., Xu, S., Werge, Thomas, Holland, D., Andreassen, O. A. & Dale, A. M., 29 Dec 2015, In: P L o S Genetics. 11, 12, p. 1-21 21 p., e1005717.Research output: Contribution to journal › Journal article › Research › peer-review
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An epigenetic clock for gestational age at birth based on blood methylation data
Knight, A. K., Craig, J. M., Theda, C., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Hollegaard, M. V., Hougaard, D. M., Mortensen, P. B., Weinsheimer, S. M., Werge, T. M., Brennan, P. A., Cubells, J. F., Newport, D. J., Stowe, Z. N., Cheong, J. L. Y., Dalach, P., Doyle, L. W., Loke, Y. J., Baccarelli, A. A. & 27 others, , 2016, In: Genome Biology (Online Edition). 17, 11 p., 206.Research output: Contribution to journal › Journal article › Research › peer-review
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An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population
Lu, T. T., Lao, O., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Nielsen, F., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A. & 14 others, , 2009, In: European Journal of Human Genetics. 17, 7, p. 967-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
Haukvik, U. K., Saetre, P., McNeil, T., Bjerkan, P. S., Andreassen, O. A., Werge, Thomas, Jönsson, E. G. & Agartz, I., 1 Oct 2010, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34, 7, p. 1259-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample
Nudel, R., Allesøe, R. L., Werge, Thomas, Thompson, W. K., Rasmussen, Simon & Benros, Michael Eriksen, 2023, In: Immunology. 168, 4, p. 622-639Research output: Contribution to journal › Journal article › Research › peer-review
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An intron 1 polymorphism in the cholecystokinin-A receptor gene associated with schizophrenia in males
Koefoed, P., Hansen, T. V. O., Woldbye, D. P. D., Werge, T., Mors, O., Hansen, T., Jakobsen, K. D., Nordentoft, M., Wang, A., Bolwig, T. G., Rehfeld, J. F., Koefoed, P., Hansen, T. V. O., Woldbye, D. P. D., Werge, T., Mors, O., Hansen, T. F., Jakobsen, K. D., Nordentoft, M., Wang, A. & 2 others, , 2009, In: Acta Psychiatrica Scandinavica. 120, 4, p. 281-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects
Passos Gregorio, S., Gattaz, W. F., Tavares, H., Kieling, C., Timm, S., Wang, August Gabriel, Berg Rasmussen, H., Werge, Thomas & Dias-Neto, E., 2006, In: Schizophrenia Research. 88, 1-3, p. 275-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control
Maurer, G. W., Malita, Alina, Nagy, S., Koyama, Takashi, Werge, Thomas, Halberg, Kenneth Veland, Texada, Michael James & Rewitz, Kim, 2020, In: PLOS Genetics. 16, 4, 31 p., e1008727.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry
Schork, A. J., iPSYCH-SSI-Broad Group, I. G. & Werge, Thomas, 2017, In: Scientific Reports. 7, 11 p., 11380.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of shared heritability in common disorders of the brain
Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 557 others, , 2018, In: Science. 360, 6395, 40 p., eaap8757.Research output: Contribution to journal › Journal article › Research › peer-review
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Ancient genomes from Iceland reveal the making of a human population
Ebenesersdóttir, S. S., Sandoval Velasco, M., Gunnarsdóttir, E. D., Jagadeesan, A., Guðmundsdóttir, V. B., Thordardóttir, E. L., Einarsdóttir, M. S., Moore, K. H. S., Sigurðsson, Á., Magnusdóttir, D. N., Jonsson, H., Snorradóttir, S., Hovig, E., Møller, P., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T., Cavalleri, G. L. & 10 others, , 2018, In: Science. 360, 6392, p. 1028-1032 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antidepressive-drug-induced bodyweight gain is associated with polymorphisms in genes coding for COMT and TPH1
Secher, A., Bukh, J., Bock, C., Koefoed, P., Rasmussen, H. B., Werge, T., Kessing, Lars Vedel, Mellerup, Erling Thyge, Secher, A., Bukh, J., Bock, C., Koefoed, P., Rasmussen, H. B., Werge, Thomas, Kessing, Lars Vedel & Mellerup, E., 2009, In: International Clinical Psychopharmacology. 24, 4, p. 199-203 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates
Andersen, M. B., Croy, C. H., Dencker, D., Werge, Thomas, Bymaster, F. P., Felder, C. C. & Fink-Jensen, Anders, 2015, In: PLOS ONE. 10, 4, p. 1-13 13 p., e0122722.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
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