An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
Research output: Contribution to journal › Journal article › Research › peer-review
Smaller hippocampal volume has repeatedly been reported in schizophrenia patients. Obstetric complications (OCs) and single nucleotide polymorphism (SNP) variation in schizophrenia susceptibility genes have independently been related to hippocampal volume. We investigated putative independent and interaction effects of severe hypoxia-related OCs and variation in four hypoxia-regulated schizophrenia susceptibility genes (BDNF, DTNBP1, GRM3 and NRG1) on hippocampal volume in schizophrenia patients and healthy controls.
| Original language | English |
|---|---|
| Journal | Progress in Neuro-Psychopharmacology & Biological Psychiatry |
| Volume | 34 |
| Issue number | 7 |
| Pages (from-to) | 1259-65 |
| Number of pages | 7 |
| ISSN | 0278-5846 |
| DOIs | |
| Publication status | Published - 1 Oct 2010 |
ID: 34193844