Thomas Werge

100 ancient genomes show repeated population turnovers in Neolithic Denmark

Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, Irving-Pease, Evan, Barrie, William, Pearson, A., Sousa da Mota, B., Demeter, Fabrice, Henriksen, Rasmus Henrik Amund, Vimala, Tharsika, McColl, Hugh, Vaughn, Andrew Howland, Vinner, Lasse, Renaud, Gabriel, Stern, A., Johannsen, N. N., Ramsøe, Abigail Daisy, Schork, A. J., Ruter, Anthony Henry, Gotfredsen, Anne Birgitte, Nielsen, B. H., Petersen, Erik Brinch, Kannegaard, E., Hansen, J., Pedersen, K. B., Pedersen, L., Klassen, L., Meldgaard, Morten, Johansen, M., Uldum, O. C., Lotz, P., Lysdahl, P., Bangsgaard, Pernille, Petersen, P. V., Maring, R., Iversen, Rune, Wåhlin, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Lynnerup, Niels, Lawson, D. J., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Kjær, Kurt H., Durbin, R., Nielsen, Rasmus, Delaneau, O., Werge, Thomas, Kristiansen, Kristian & Willerslev, Eske, 2024, In: Nature. 625, 7994, p. 329-337 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes

Forsingdal, A., Fejgin, K., Nielsen, V., Werge, Thomas & Nielsen, J., 2016, In: Translational Psychiatry. 6, 7, p. 1-9 9 p., e860.

Research output: Contribution to journal › Journal article › Research › peer-review

22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response

Larsen, K. M., Pellegrino, G., Birknow, M. R., Kjær, T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Mørup, M. & Siebner, Hartwig Roman, 2018, In: Schizophrenia Bulletin. 44, 2, p. 388–397

Research output: Contribution to journal › Journal article › Research › peer-review

FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Agerbo, E., Gern, J. E., Lemanske, R. F., Ober, C., Pedersen, A. G., Bisgaard, H. & Bønnelykke, Klaus, 2020, In: Nature Communications. 11, 12 p., 6398.

Research output: Contribution to journal › Journal article › Research › peer-review

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., Brikell, I., Ghirardi, L., Larsson, H., Lichtenstein, P., Eriksson, N., 23andMe Research Team, 2. R. T., Psychiatric Genomics Consortium: ADHD Subgroup, P. G. C. A. S., iPSYCH–Broad ADHD Workgroup, I. A. W., Werge, Thomas & Nordentoft, Merete, 15 Jun 2018, In: Biological Psychiatry. 83, 12, p. 1044-1053 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A closed-tube assay for genotyping of the 32-bp deletion polymorphism in the chemokine receptor 5 (CCR5) gene: dissociation analysis of amplified fragments of DNA

Rasmussen, H. B. & Werge, Thomas, 2007, In: Molecular and Cellular Probes. 21, 1, p. 8-11 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A comprehensive family-based replication study of schizophrenia genes

Aberg, K. A., Liu, Y., Bukszár, J., McClay, J. L., Khachane, A. N., Andreassen, O. A., Blackwood, D., Corvin, A., Djurovic, S., Gurling, H., Ophoff, R., Pato, C. N., Pato, M. T., Riley, B., Webb, T., Kendler, K., O'Donovan, M., Craddock, N., Kirov, G., Owen, M. & 7 others, Rujescu, D., St Clair, D., Werge, Thomas, Hultman, C. M., Delisi, L. E., Sullivan, P. & van den Oord, E. J., 1 Feb 2013, In: JAMA psychiatry (Chicago, Ill.). 70, 2, p. 1-9 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

Athanasiadis, G., Meijsen, J. J., Helenius, D., Schork, A. J., Ingason, A., Thompson, W. K., Geschwind, D. H., Werge, Thomas & Buil, A., 2022, In: PNAS. 119, 6, 9 p., e2118688119.

Research output: Contribution to journal › Journal article › Research › peer-review

A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions

Nudel, R., Zetterberg, R., Hemager, N., Christiani, C. A. J., Ohland, J., Burton, B. K., Greve, A. N., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Bybjerg-Grauholm, J., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Mors, O. & Nordentoft, Merete, 2022, In: Behavioral and Brain Functions. 18, 14.

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D., Bo Mortensen, P. & 4 others, Buil, A., Thompson, W. K., Geschwind, D. H. & Werge, Thomas, Mar 2019, In: Nature Neuroscience. 22, 3, p. 353-361

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Hrafnsdottir, M. G., Stefansson, H., Ring, S. M., Hottenga, J. J., Penninx, B. W. J. H., Färkkilä, M., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Christensen, A. F., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, The International Headache Genetics Consortium, T. I. H. G. C. & the 23andMe Research Team, T. 2. R. T., 2020, In: Nature Communications. 11, 1, 3368.

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

Bell, S., Rigas, A. S., Magnusson, M. K., Ferkingstad, E., Allara, E., Bjornsdottir, G., Ramond, A., Sørensen, E., Halldorsson, G. H., Paul, D. S., Burgdorf, K. S., Eggertsson, H. P., Howson, J. M. M., Thørner, L. W., Kristmundsdottir, S., Astle, W. J., Erikstrup, C., Sigurdsson, J. K., Vuckovic, D., Dinh, K. M. & 31 others, Tragante, V., Surendran, P., Pedersen, Ole Birger Vesterager, Vidarsson, B., Jiang, T., Paarup, H. M., Onundarson, P. T., Akbari, P., Nielsen, K. R., Lund, S. H., Juliusson, K., Magnusson, M. I., Frigge, M. L., Oddsson, A., Olafsson, I., Kaptoge, S., Hjalgrim, Henrik, Runarsson, G., Wood, A. M., Hansen, Thomas Folkmann, Burgdorf, Kristoffer Sølvsten, Jemec, Gregor, Jennum, Poul, Nielsen, K. R., Petersen, M., Werge, Thomas, Westergaard, David, Banasik, Karina, Brunak, Søren, Ullum, H. & DBDS Genomic Consortium, D. G. C., 2021, In: Communications Biology . 4, 1, 14 p., 156.

Research output: Contribution to journal › Journal article › Research › peer-review

A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness

Nudel, R., Appadurai, V., Schork, A. J., Buil, A., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, Mar 2020, In: Human Genetics. 139, p. 593-604

Research output: Contribution to journal › Journal article › Research › peer-review

A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia

Ingason, A., Giegling, I., Cichon, S., Hansen, T., Rasmussen, H. B., Nielsen, J., Jürgens, G., Muglia, P., Hartmann, A. M., Strengman, E., Vasilescu, C., Mühleisen, T. W., Djurovic, S., Melle, I., Lerer, B., Möller, H-J., Francks, C., Pietiläinen, O. P. H., Lonnqvist, J., Suvisaari, J. & 21 others, Tuulio-Henriksson, A., Walshe, M., Vassos, E., Di Forti, M., Murray, R., Bonetto, C., Tosato, S., Cantor, R. M., Rietschel, M., Craddock, N., Owen, M. J., Peltonen, L., Andreassen, O. A., Nöthen, M. M., St Clair, D., Ophoff, R. A., O'Donovan, M. C., Collier, D. A., Werge, Thomas, Rujescu, D. & GROUP Investigators, G. I., 1 Apr 2010, In: Human Molecular Genetics. 19, 7, p. 1379-86 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A large-scale genome-wide association study meta-analysis of cannabis use disorder

Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., Sanchez-Roige, S., Paul, S. E., Wendt, F. R., Clarke, T. K., Lai, D., Reginsson, G. W., Zhou, H., He, J., Baranger, D. A. A., Gudbjartsson, D. F., Wedow, R., Adkins, D. E., Adkins, A. E., Alexander, J. & 31 others, Bacanu, S. A., Bigdeli, T. B., Boden, J., Brown, S. A., Bucholz, K. K., Bybjerg-Grauholm, J., Corley, R. P., Degenhardt, L., Dick, D. M., Domingue, B. W., Fox, L., Goate, A. M., Gordon, S. D., Hack, L. M., Hancock, D. B., Hartz, S. M., Hickie, I. B., Hougaard, D. M., Krauter, K., Lind, P. A., McClintick, J. N., McQueen, M. B., Meyers, J. L., Montgomery, G. W., Mors, O., Mortensen, P. B., Nordentoft, Merete, Pearson, J. F., Peterson, R. E., Werge, Thomas & Psychiatric Genomics Consortium Substance Use Disorders Workgroup, P. G. C. S. U. D. W., 2020, In: The Lancet Psychiatry. 7, 12, p. 1032-1045 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

Nudel, R., Wang, Y., Appadurai, V., Schork, A. J., Buil, A., Agerbo, E., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, 2019, In: Translational Psychiatry. 9, 1, 10 p., 283.

Research output: Contribution to journal › Journal article › Research › peer-review

A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders

Nudel, R., Allesøe, R. L., Thompson, W. K., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2021, In: Journal of Translational Medicine. 19, 230.

Research output: Contribution to journal › Journal article › Research › peer-review

A major role for common genetic variation in anxiety disorders

Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O., Bo Mortensen, P. & 6 others, Nordentoft, Merete, Werge, Thomas, Nicodemus, K. K., Mattheisen, M., Breen, G. & Eley, T. C., 2020, In: Molecular Psychiatry. 25, p. 3292–3303

Research output: Contribution to journal › Journal article › Research › peer-review

A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission

Nielsen, J., Fejgin, K., Sotty, F., Nielsen, V., Mørk, A., Christoffersen, C. T., Yavich, L., Lauridsen, J. B., Clausen, D., Larsen, P. H., Egebjerg, J., Werge, Thomas, Kallunki, P., Christensen, K. V. & Didriksen, M., 30 Nov 2017, In: Translational Psychiatry. 7, 12 p., 1261.

Research output: Contribution to journal › Journal article › Research › peer-review

A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. K., Adams, M. J., Clarke, T. K., McIntosh, A. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M. & 31 others, Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Foo, J. C., Hansen, C. S., Hansen, T. F., Pedersen, C. B., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Nature Communications. 11, 1, 2301.

Research output: Contribution to journal › Journal article › Research › peer-review

A polygenic resilience score moderates the genetic risk for schizophrenia

Hess, J. L., Tylee, D. S., Mattheisen, M., The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum, A. D., Als, T. D., Grove, J., Werge, T., Mortensen, P. B., Mors, O., Nordentoft, M., Hougaard, D. M., Byberg-grauholm, J., Bækvad-hansen, M., Greenwood, T. A., Tsuang, M. T., Curtis, D., Steinberg, S., Sigurdsson, E. & 6 others, Stefánsson, H., Stefánsson, K., Edenberg, H. J., Holmans, P., Faraone, S. V. & Glatt, S. J., 2021, In: Molecular Psychiatry. 26, p. 800–815

Research output: Contribution to journal › Journal article › Research › peer-review

A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)

Djurovic, S., Kähler, A. K., Kulle, B., Jönsson, E. G., Agartz, I., Le Hellard, S., Hall, H., Jakobsen, K. D., Hansen, T., Melle, I., Werge, T., Steen, V. M., Andreassen, O. A., Djurovic, S., Kähler, A. K., Kulle, B., Jönsson, E. G., Agartz, I., Le Hellard, S., Hall, H. & 6 others, Jakobsen, K. D., Hansen, T. F., Melle, I., Werge, Thomas, Steen, V. M. & Andreassen, O. A., 2009, In: Schizophrenia Research. 107, 2-3, p. 242-8 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

Holm, H., Gudbjartsson, D. F., Sulem, P., Masson, G., Helgadottir, H. T., Zanon, C., Magnusson, O. T., Helgason, A., Saemundsdottir, J., Gylfason, A., Stefansdottir, H., Gretarsdottir, S., Matthiasson, S. E., Thorgeirsson, G. M., Jonasdottir, A., Sigurdsson, A., Stefansson, H., Werge, T., Rafnar, T., Kiemeney, L. A. & 10 others, Parvez, B., Muhammad, R., Roden, D. M., Darbar, D., Thorleifsson, G., Walters, G. B., Kong, A., Thorsteinsdottir, U., Arnar, D. O. & Stefansson, K., 1 Apr 2011, In: Nature Genetics. 43, 4, p. 316-20 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A saturated map of common genetic variants associated with human height

Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, J., Møllehave, Line Tang, Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, Niels, Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

Research output: Contribution to journal › Journal article › Research › peer-review

A study of the genetic architecture of social responsiveness in families with parental schizophrenia or bipolar disorder and population-based controls

Veddum, L., Greve, A. N., Gregersen, M., Andreassen, A. K., Knudsen, C. B., Brandt, J. M., Krantz, M. F., Søndergaard, A., Burton, B. K., Jepsen, J. R. M., Hemager, N., Werge, Thomas, Thorup, Anne, Nordentoft, Merete, Mors, O. & Nudel, R., 2023, In: Psychiatry Research. 326, 115280.

Research output: Contribution to journal › Journal article › Research › peer-review

ADuLT: An efficient and robust time-to-event GWAS

Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Steinbach, J., Krebs, M. D., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Børglum, A. D., Musliner, K. L., Ganna, A., Schork, A. J., Mortensen, P. B., McGrath, J. J., Privé, F. & Vilhjálmsson, B. J., 2023, In: Nature Communications. 14, 12 p., 5553.

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AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance

Nagy, S., Maurer, G. W., Hentze, J. L., Rose, M., Werge, Thomas & Rewitz, Kim, 2018, In: PLOS Genetics. 14, 12, e1007623.

Research output: Contribution to journal › Journal article › Research › peer-review

ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties

St Pourcain, B., Robinson, E. B., Anttila, V., Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., Zammit, S., Fisher, S. E., Neale, B. M., Anney, R. J. L., Ripke, S., Hollegaard, M. V., Werge, T., iPSYCH-SSI-Broad Autism Group, Ronald, A., Grove, J., Hougaard, D. M. & 4 others, Børglum, A. D., Mortensen, P. B., Daly, M. J. & Davey Smith, G., 2018, In: Molecular Psychiatry. 23, 2, p. 263-270

Research output: Contribution to journal › Journal article › Research › peer-review

Accounting for age of onset and family history improves power in genome-wide association studies

Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J., Privé, F. & 1 others, Vilhjálmsson, B. J., 2022, In: American Journal of Human Genetics. 109, 3, p. 417-432 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Accumulation of Disadvantages Across Multiple Domains Amongst Subgroups of Children of Parents with Schizophrenia or Bipolar Disorder: Clustering Data from the Danish High Risk and Resilience Study VIA 7

Krantz, M. F., Ellersgaard, D., Andersen, K. K., Hemager, N., Christiani, C., Spang, K. S., Burton, B. K., Gregersen, M., Søndergaard, A., Greve, A., Gantriis, D. L., Ohland, J., Mortensen, P. B., Werge, T., Nudel, R., Wang, Y., Hougaard, D. M., Plessen, K. J., Bliksted, V., Jepsen, J. R. M. & 3 others, Thorup, Anne, Mors, O. & Nordentoft, Merete, 2022, In: Schizophrenia Bulletin Open. 3, 1, 16 p., sgac010.

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Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks

Appadurai, V., Bybjerg-Grauholm, J., Krebs, M. D., Rosengren, A., Buil, A., Ingason, A., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Delaneau, O., Werge, Thomas & Schork, A. J., 2023, In: Communications Biology . 6, 101.

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Accurate and Effective Detection of Recurrent Copy Number Variants in Large SNP Genotype Datasets

Montalbano, S., Sánchez, X. C., Vaez, M., Helenius, D., Werge, Thomas & Ingason, A., 2022, In: Current Protocols. 2, 12, 21 p., e621.

Research output: Contribution to journal › Journal article › Research › peer-review

Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression

Paksarian, D., Trabjerg, B. B., Merikangas, K. R., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Pedersen, C. B., Mortensen, P. B., Agerbo, E. & Horsdal, H. T., 2020, In: British Journal of Psychiatry. 217, 1, p. 390-396 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Advice on the genotyping of CYP2C19: comments on a recent article

Rasmussen, H. B. & Werge, Thomas, 2008, In: Pharmacogenetics and Genomics (Print Edition). 18, 7, p. 647-648 1 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Age at first birth in women is genetically associated with increased risk of schizophrenia

Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chen, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Del Favero, J., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodríguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Haan, L. D., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, Thomas Folkmann, Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Juliá, A., Kahn, R. S., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kähler, A. K., Laurent, C., Keong, J. L. C., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lönnqvist, J., Macek, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Müller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'callaghan, E., O'dushlaine, C., O'neill, F. A., Oh, S. Y., Olincy, A., Olsen, L., Os, J. V., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietiläinen, O., Pimm, J., Pocklington, A. J., Powell, J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stahl, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Stroup, T. S., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Cichon, S., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gill, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jönsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarroll, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Nöthen, M. M., Ophoff, R. A., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Rietschel, M., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, Thomas, Daly, M. J., Sullivan, P. F. & O'donovan, M. C., 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.

Research output: Contribution to journal › Journal article › Research › peer-review

Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome

Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Siebner, Hartwig Roman & Garrido, M. I., 2018, In: Schizophrenia Research. 197, p. 328-336

Research output: Contribution to journal › Journal article › Research › peer-review

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

Thompson, W. K., Wang, Y., Schork, A. J., Witoelar, A., Zuber, V., Xu, S., Werge, Thomas, Holland, D., Andreassen, O. A. & Dale, A. M., 29 Dec 2015, In: P L o S Genetics. 11, 12, p. 1-21 21 p., e1005717.

Research output: Contribution to journal › Journal article › Research › peer-review

An epigenetic clock for gestational age at birth based on blood methylation data

Knight, A. K., Craig, J. M., Theda, C., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Hollegaard, M. V., Hougaard, D. M., Mortensen, P. B., Weinsheimer, S. M., Werge, T. M., Brennan, P. A., Cubells, J. F., Newport, D. J., Stowe, Z. N., Cheong, J. L. Y., Dalach, P., Doyle, L. W., Loke, Y. J., Baccarelli, A. A. & 27 others, Just, A. C., Wright, R. O., Téllez-rojo, M. M., Svensson, K., Trevisi, L., Kennedy, E. M., Binder, E. B., Iurato, S., Czamara, D., Räikkönen, K., Lahti, J. M. T., Pesonen, A., Kajantie, E., Villa, P. M., Laivuori, H., Hämäläinen, E., Park, H. J., Bailey, L. B., Parets, S. E., Kilaru, V., Menon, R., Horvath, S., Bush, N. R., Lewinn, K. Z., Tylavsky, F. A., Conneely, K. N. & Smith, A. K., 2016, In: Genome Biology (Online Edition). 17, 11 p., 206.

Research output: Contribution to journal › Journal article › Research › peer-review

An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population

Lu, T. T., Lao, O., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Nielsen, F., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A. & 14 others, Gether, Ulrik, Werge, Thomas, Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Gieger, C., Wichmann, H., Ruether, A., Schreiber, S., Becker, C., Nürnberg, P., Nelson, M. R., Kayser, M. & Krawczak, M., 2009, In: European Journal of Human Genetics. 17, 7, p. 967-75 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes

Haukvik, U. K., Saetre, P., McNeil, T., Bjerkan, P. S., Andreassen, O. A., Werge, Thomas, Jönsson, E. G. & Agartz, I., 1 Oct 2010, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34, 7, p. 1259-65 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample

Nudel, R., Allesøe, R. L., Werge, Thomas, Thompson, W. K., Rasmussen, Simon & Benros, Michael Eriksen, 2023, In: Immunology. 168, 4, p. 622-639

Research output: Contribution to journal › Journal article › Research › peer-review

An intron 1 polymorphism in the cholecystokinin-A receptor gene associated with schizophrenia in males

Koefoed, P., Hansen, T. V. O., Woldbye, D. P. D., Werge, T., Mors, O., Hansen, T., Jakobsen, K. D., Nordentoft, M., Wang, A., Bolwig, T. G., Rehfeld, J. F., Koefoed, P., Hansen, T. V. O., Woldbye, D. P. D., Werge, T., Mors, O., Hansen, T. F., Jakobsen, K. D., Nordentoft, M., Wang, A. & 2 others, Bolwig, T. G. & Rehfeld, J. F., 2009, In: Acta Psychiatrica Scandinavica. 120, 4, p. 281-7 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects

Passos Gregorio, S., Gattaz, W. F., Tavares, H., Kieling, C., Timm, S., Wang, August Gabriel, Berg Rasmussen, H., Werge, Thomas & Dias-Neto, E., 2006, In: Schizophrenia Research. 88, 1-3, p. 275-82 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control

Maurer, G. W., Malita, Alina, Nagy, S., Koyama, Takashi, Werge, Thomas, Halberg, Kenneth Veland, Texada, Michael James & Rewitz, Kim, 2020, In: PLOS Genetics. 16, 4, 31 p., e1008727.

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry

Schork, A. J., iPSYCH-SSI-Broad Group, I. G. & Werge, Thomas, 2017, In: Scientific Reports. 7, 11 p., 11380.

Research output: Contribution to journal › Journal article › Research › peer-review

Analysis of shared heritability in common disorders of the brain

Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 557 others, Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Leverenz, J. B., Levey, A. I., Lieberman, A. P., Pankratz, V. S., Poon, W. W., Quinn, J. F., Saykin, A. J., Schneider, L. S., Smith, A. G., Sonnen, J. A., Stern, R. A., Van Deerlin, V. M., Van Eldik, L. J., Harold, D., Russo, G., Rubinsztein, D. C., Bayer, A., Tsolaki, M., Proitsi, P., Fox, N. C., Hampel, H., Owen, M. J., Mead, S., Passmore, P., Morgan, K., Nöthen, M. M., Schott, J. M., Rossor, M., Lupton, M. K., Hoffmann, P., Kornhuber, J., Lawlor, B., Mcquillin, A., Al-Chalabi, A., Bis, J. C., Ruiz, A., Boada, M., Seshadri, S., Beiser, A., Rice, K., Van Der Lee, S. J., De Jager, P. L., Geschwind, D. H., Riemenschneider, M., Riedel-Heller, S., Rotter, J. I., Ransmayr, G., Hyman, B. T., Cruchaga, C., Alegret, M., Winsvold, B., Palta, P., Farh, K., Cuenca-Leon, E., Furlotte, N., Kurth, T., Ligthart, L., Terwindt, G. M., Freilinger, T., Ran, C., Gordon, S. D., Borck, G., Adams, H. H. H., Lehtimäki, T., Wedenoja, J., Buring, J. E., Schürks, M., Hrafnsdottir, M., Hottenga, J., Penninx, B., Artto, V., Kaunisto, M., Vepsäläinen, S., Martin, N. G., Montgomery, G. W., Kurki, M. I., Hämäläinen, E., Huang, H., Huang, J., Sandor, C., Webber, C., Muller-Myhsok, B., Schreiber, S., Salomaa, V., Loehrer, E., Göbel, H., Macaya, A., Pozo-Rosich, P., Hansen, T., Werge, Thomas, Kaprio, J., Metspalu, A., Kubisch, C., Ferrari, M. D., Belin, A. C., Van Den Maagdenberg, A. M. J. M., Zwart, J., Boomsma, D., Eriksson, N., Olesen, Jes, Chasman, D. I., Nyholt, D. R., Anney, R., Avbersek, A., Baum, L., Berkovic, S., Bradfield, J., Buono, R., Catarino, C. B., Cossette, P., De Jonghe, P., Depondt, C., Dlugos, D., Ferraro, T. N., French, J., Hjalgrim, H., Jamnadas-khoda, J., Kälviäinen, R., Kunz, W. S., Lerche, H., Leu, C., Lindhout, D., Lo, W., Lowenstein, D., Mccormack, M., Møller, R. S., Molloy, A., Ng, P., Oliver, K., Privitera, M., Radtke, R., Ruppert, A., Sander, T., Schachter, S., Schankin, C., Scheffer, I., Schoch, S., Sisodiya, S. M., Smith, P., Sperling, M., Striano, P., Surges, R., Thomas, G. N., Visscher, F., Whelan, C. D., Zara, F., Heinzen, E. L., Marson, A., Becker, F., Stroink, H., Zimprich, F., Gasser, T., Gibbs, R., Heutink, P., Martinez, M., Morris, H. R., Sharma, M., Ryten, M., Mok, K. Y., Pulit, S., Bevan, S., Holliday, E., Attia, J., Battey, T., Boncoraglio, G., Thijs, V., Chen, W., Mitchell, B., Rothwell, P., Sharma, P., Sudlow, C., Vicente, A., Markus, H., Kourkoulis, C., Pera, J., Raffeld, M., Silliman, S., Boraska Perica, V., Thornton, L. M., Huckins, L. M., William Rayner, N., Lewis, C. M., Gratacos, M., Rybakowski, F., Keski-Rahkonen, A., Raevuori, A., Hudson, J. I., Reichborn-Kjennerud, T., Monteleone, P., Karwautz, A., Mannik, K., Baker, J. H., O’toole, J. K., Trace, S. E., Davis, O. S. P., Helder, S. G., Ehrlich, S., Herpertz-dahlmann, B., Danner, U. N., Van Elburg, A. A., Clementi, M., Forzan, M., Docampo, E., Lissowska, J., Hauser, J., Tortorella, A., Maj, M., Gonidakis, F., Tziouvas, K., Papezova, H., Yilmaz, Z., Wagner, G., Cohen-woods, S., Herms, S., Julià, A., Rabionet, R., Dick, D. M., Ripatti, S., Andreassen, O. A., Espeseth, T., Lundervold, A. J., Steen, V. M., Pinto, D., Scherer, S. W., Aschauer, H., Schosser, A., Alfredsson, L., Padyukov, L., Halmi, K. A., Mitchell, J., Strober, M., Bergen, A. W., Kaye, W., Szatkiewicz, J. P., Cormand, B., Ramos-quiroga, J. A., Sánchez-mora, C., Ribasés, M., Casas, M., Hervas, A., Arranz, M. J., Haavik, J., Zayats, T., Johansson, S., Williams, N., Elia, J., Dempfle, A., Rothenberger, A., Kuntsi, J., Oades, R. D., Banaschewski, T., Franke, B., Buitelaar, J. K., Arias Vasquez, A., Doyle, A. E., Reif, A., Lesch, K., Freitag, C., Rivero, O., Palmason, H., Romanos, M., Langley, K., Rietschel, M., Witt, S. H., Dalsgaard, S., Børglum, A. D., Waldman, I., Wilmot, B., Molly, N., Bau, C. H. D., Crosbie, J., Schachar, R., Loo, S. K., Mcgough, J. J., Grevet, E. H., Medland, S. E., Robinson, E., Weiss, L. A., Bacchelli, E., Bailey, A., Bal, V., Battaglia, A., Betancur, C., Bolton, P., Cantor, R., Celestino-soper, P., Dawson, G., De Rubeis, S., Duque, F., Green, A., Klauck, S. M., Leboyer, M., Levitt, P., Maestrini, E., Mane, S., De-luca, D. M., Parr, J., Regan, R., Reichenberg, A., Sandin, S., Vorstman, J., Wassink, T., Wijsman, E., Cook, E., Santangelo, S., Delorme, R., Rogé, B., Magalhaes, T., Arking, D., Schulze, T. G., Thompson, R. C., Strohmaier, J., Matthews, K., Melle, I., Morris, D., Blackwood, D., Mcintosh, A., Bergen, S. E., Schalling, M., Jamain, S., Maaser, A., Fischer, S. B., Reinbold, C. S., Fullerton, J. M., Grigoroiu-serbanescu, M., Guzman-parra, J., Mayoral, F., Schofield, P. R., Cichon, S., Mühleisen, T. W., Degenhardt, F., Schumacher, J., Bauer, M., Mitchell, P. B., Gershon, E. S., Rice, J., Potash, J. B., Zandi, P. P., Craddock, N., Ferrier, I. N., Alda, M., Rouleau, G. A., Turecki, G., Ophoff, R., Pato, C., Anjorin, A., Stahl, E., Leber, M., Czerski, P. M., Edenberg, H. J., Cruceanu, C., Jones, I. R., Posthuma, D., Andlauer, T. F. M., Forstner, A. J., Streit, F., Baune, B. T., Air, T., Sinnamon, G., Wray, N. R., Macintyre, D. J., Porteous, D., Homuth, G., Rivera, M., Grove, J., Middeldorp, C. M., Hickie, I., Pergadia, M., Mehta, D., Smit, J. H., Jansen, R., De Geus, E., Dunn, E., Li, Q. S., Nauck, M., Schoevers, R. A., Beekman, A. T., Knowles, J. A., Viktorin, A., Arnold, P., Barr, C. L., Bedoya-berrio, G., Bienvenu, O. J., Brentani, H., Burton, C., Camarena, B., Cappi, C., Cath, D., Cavallini, M., Cusi, D., Darrow, S., Denys, D., Derks, E. M., Dietrich, A., Fernandez, T., Figee, M., Freimer, N., Gerber, G., Grados, M., Greenberg, E., Hanna, G. L., Hartmann, A., Hirschtritt, M. E., Hoekstra, P. J., Huang, A., Huyser, C., Illmann, C., Jenike, M., Kuperman, S., Leventhal, B., Lochner, C., Lyon, G. J., Macciardi, F., Madruga-garrido, M., Malaty, I. A., Maras, A., Mcgrath, L., Miguel, E. C., Mir, P., Nestadt, G., Nicolini, H., Okun, M. S., Pakstis, A., Paschou, P., Piacentini, J., Pittenger, C., Plessen, K., Ramensky, V., Ramos, E. M., Reus, V., Richter, M. A., Riddle, M. A., Robertson, M. M., Roessner, V., Rosário, M., Samuels, J. F., Sandor, P., Stein, D. J., Tsetsos, F., Van Nieuwerburgh, F., Weatherall, S., Wendland, J. R., Wolanczyk, T., Worbe, Y., Zai, G., Goes, F. S., Mclaughlin, N., Nestadt, P. S., Grabe, H., Depienne, C., Konkashbaev, A., Lanzagorta, N., Valencia-duarte, A., Bramon, E., Buccola, N., Cahn, W., Cairns, M., Chong, S. A., Cohen, D., Crespo-facorro, B., Crowley, J., Davidson, M., Delisi, L., Dinan, T., Donohoe, G., Drapeau, E., Duan, J., Haan, L., Hougaard, D., Karachanak-yankova, S., Khrunin, A., Klovins, J., Kučinskas, V., Lee Chee Keong, J., Limborska, S., Loughland, C., Lönnqvist, J., Maher, B., Mattheisen, M., Mcdonald, C., Murphy, K. C., Murray, R., Nenadic, I., Van Os, J., Pantelis, C., Pato, M., Petryshen, T., Quested, D., Roussos, P., Sanders, A. R., Schall, U., Schwab, S. G., Sim, K., So, H., Stögmann, E., Subramaniam, M., Toncheva, D., Waddington, J., Walters, J., Weiser, M., Cheng, W., Cloninger, R., Curtis, D., Gejman, P. V., Henskens, F., Mattingsdal, M., Oh, S., Scott, R., Webb, B., Breen, G., Churchhouse, C., Bulik, C. M., Daly, M., Dichgans, M., Faraone, S. V., Guerreiro, R., Holmans, P., Kendler, K. S., Koeleman, B., Mathews, C. A., Price, A., Scharf, J., Sklar, P., Williams, J., Wood, N. W., Cotsapas, C., Palotie, A., Smoller, J. W., Sullivan, P., Rosand, J., Corvin, A. & Neale, B. M., 2018, In: Science. 360, 6395, 40 p., eaap8757.

Research output: Contribution to journal › Journal article › Research › peer-review

Ancient genomes from Iceland reveal the making of a human population

Ebenesersdóttir, S. S., Sandoval Velasco, M., Gunnarsdóttir, E. D., Jagadeesan, A., Guðmundsdóttir, V. B., Thordardóttir, E. L., Einarsdóttir, M. S., Moore, K. H. S., Sigurðsson, Á., Magnusdóttir, D. N., Jonsson, H., Snorradóttir, S., Hovig, E., Møller, P., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T., Cavalleri, G. L. & 10 others, Gilbert, E., Lalueza-Fox, C., Walser, J. ,. I., Kristjánsdóttir, S., Gopalakrishnan, Shyam, Árnadóttir, L., Magnússon, Ó. Þ., Gilbert, M Thomas P, Stefánsson, K. & Helgason, A., 2018, In: Science. 360, 6392, p. 1028-1032 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Antidepressive-drug-induced bodyweight gain is associated with polymorphisms in genes coding for COMT and TPH1

Secher, A., Bukh, J., Bock, C., Koefoed, P., Rasmussen, H. B., Werge, T., Kessing, Lars Vedel, Mellerup, Erling Thyge, Secher, A., Bukh, J., Bock, C., Koefoed, P., Rasmussen, H. B., Werge, Thomas, Kessing, Lars Vedel & Mellerup, E., 2009, In: International Clinical Psychopharmacology. 24, 4, p. 199-203 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates

Andersen, M. B., Croy, C. H., Dencker, D., Werge, Thomas, Bymaster, F. P., Felder, C. C. & Fink-Jensen, Anders, 2015, In: PLOS ONE. 10, 4, p. 1-13 13 p., e0122722.

Research output: Contribution to journal › Journal article › Research › peer-review

Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study

Choi, K. W., Chen, C. Y., Stein, M. B., Klimentidis, Y. C., Wang, M. J., Koenen, K. C., Smoller, J. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F. & 31 others, Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T. K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Hansen, T. F., Krogh, J., Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: JAMA Psychiatry. 76, 4, p. 399-408 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia

Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M., McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, Merete, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, Thomas, Svenning, J. C. & Horsdal, H. T., 2020, In: Schizophrenia Bulletin. 46, 6, p. 1629-1637 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association Study of CHRNA₇ Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study

Bertelsen, B., Oranje, B., Melchior, L., Fagerlund, Birgitte, Werge, Thomas, Mikkelsen, Jens D., Tümer, Asuman Zeynep & Glenthøj, Birte Yding, Dec 2015, In: NeuroMolecular Medicine. 17, 4, p. 423-30 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples

Tesli, M., Koefoed, P., Athanasiu, L., Mattingsdal, M., Gustafsson, O., Agartz, I., Rimol, L. M., Brown, A., Wirgenes, K. V., Smorr, L., Kähler, A. K., Werge, Thomas, Mors, O., Mellerup, Erling Thyge, Jönsson, E. G., Melle, I., Morken, G., Djurovic, S. & Andreassen, O. A., 1 Dec 2011, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 8, p. 969-74 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample

Tesli, M., Athanasiu, L., Mattingsdal, M., Kähler, A. K., Gustafsson, O., Andreassen, B. K., Werge, Thomas, Hansen, T., Mors, O., Mellerup, Erling Thyge, Koefoed, P., Jönsson, E. G., Agartz, I., Melle, I., Morken, G., Djurovic, S. & Andreassen, O. A., Oct 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 7, p. 1276-82 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene

Kähler, A. K., Djurovic, S., Kulle, B., Jönsson, E. G., Agartz, I., Hall, H., Opjordsmoen, S., Jakobsen, K. D., Hansen, T., Melle, I., Werge, Thomas, Steen, V. M. & Andreassen, O. A., 2008, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 147B, 7, p. 1089-100 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association and genetic overlap between clinical chemistry tests and migraine

Tanha, H. M. & The International Headache Genetics Consortium (IHGC), T. I. H. G. C. (., 2021, In: Cephalalgia. 41, 11-12, p. 1208-1221 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association between GLP-1 receptor gene polymorphisms with reward Learning, anhedonia, and depression diagnosis

Eser, H. Y., Appadurai, V., Eren, C. Y., Yazici, D., Chen, C. Y., Ongur, D., Pizzagalli, D. A., Werge, Thomas & Hall, M. H., 2020, In: Acta Neuropsychiatrica. 32, 4, p. 218-225

Research output: Contribution to journal › Journal article › Research › peer-review

Association between Mental Disorders and Subsequent Medical Conditions

Momen, N. C., Plana-Ripoll, O., Agerbo, E., Benros, M. E., Børglum, A. D., Christensen, M. K., Dalsgaard, S., Degenhardt, L., de Jonge, P., Debost, J-C. P. G., Fenger-Grøn, M., Gunn, J. M., Iburg, K. M., Kessing, L. V., Kessler, R. C., Laursen, T. M., Lim, C. C. W., Mors, O., Mortensen, P. B., Musliner, K. L. & 18 others, Nordentoft, Merete, Pedersen, C. B., Petersen, L. V., Ribe, A. R., Roest, A. M., Saha, S., Schork, A. J., Scott, K. M., Sievert, C., Sørensen, H. J., Stedman, T. J., Vestergaard, M., Vilhjalmsson, B., Werge, Thomas, Weye, N., Whiteford, H. A., Prior, A. & McGrath, J. J., 2020, In: The New England Journal of Medicine. 382, 18, p. 1721-1731 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia

Lindholm Carlstrom, E., Saetre, P., Rosengren, A., Thygesen, J. H., Djurovic, S., Melle, I., Andreassen, O. A., Werge, Thomas, Agartz, I., Hall, H., Terenius, L. & Jönsson, E. G., May 2012, In: Behavioral and Brain Functions. 8, 1, 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia

Vares, M., Saetre, P., Deng, H., Cai, G., Liu, X., Hansen, Thomas Folkmann, Rasmussen, Henrik Berg, Werge, Thomas, Melle, I., Djurovic, S., Andreassen, O. A., Agartz, I., Hall, H., Terenius, L. & Jönsson, E. G., 5 Mar 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 2, p. 610-8 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association between the CCR5 32-bp deletion allele and late onset of schizophrenia

Rasmussen, H. B., Timm, S., Wang, A. G., Soby, K., Lublin, H., Fenger, M., Hemmingsen, R., Werge, T., Rasmussen, H. B., Timm, S., Wang, August Gabriel, Søeby, K., Lublin, H., Hemmingsen, R. P. A. & Werge, Thomas, 2006, In: American Journal of Psychiatry. 163, 3, p. 507-11 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of AADAC Deletion and Gilles de la Tourette Syndrome in a Large European Cohort

Bertelsen, B., Stefánsson, H., Riff Jensen, L., Melchior, L., Debes, N. M., Groth, C., Skov, L., Werge, T., Karagiannidis, I., Tarnok, Z., Barta, C., Nagy, P., Farkas, L., Brøndum-Nielsen, K., Rizzo, R., Gulisano, M., Rujescu, D., Kiemeney, L. A., Tosato, S., Nawaz, M. S. & 14 others, Ingason, A., Unnsteinsdottir, U., Steinberg, S., Ludvigsson, P., Stefansson, K., Kuss, A. W., Paschou, P., Cath, D., Hoekstra, P. J., Müller-Vahl, K., Stuhrmann, M., Silahtaroglu, Asli, Pfundt, R. & Tümer, Z., 1 Mar 2016, In: Biological Psychiatry. 79, 5, p. 383–391 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia

Horsdal, H. T., Agerbo, E., McGrath, J. J., Vilhjálmsson, B. J., Antonsen, S., Closter, A. M., Timmermann, A., Grove, J., Mok, P. L. H., Webb, R. T., Sabel, C. E., Hertel, O., Sigsgaard, T., Erikstrup, C., Hougaard, D. M., Werge, T., Nordentoft, M., Børglum, A. D., Mors, O., Mortensen, P. B. & 3 others, Brandt, J., Geels, C. & Pedersen, C. B., 2019, In: JAMA Network Open. 2, 11, 12 p., e1914401.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of GRIN1 and GRIN2A-D With schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk

Demontis, D., Nyegaard, M., Buttenschøn, H. N., Hedemand, A., Pedersen, C. B., Grove, J., Zacharov, T. F., Nordentoft, Merete, Werge, Thomas, Hougaard, D. M., Sørensen, K. M., Yolken, R. H., Mors, O., Børglum, A. & Mortensen, P. B., 1 Dec 2011, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 8, p. 913-22 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)

Djurovic, S., Le Hellard, S., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G., Rasmussen, H. B., Melle, I., Werge, T., Andreassen, O. A., Djurovic, S., Le Hellard, S., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G. & 4 others, Rasmussen, H. B., Melle, I., Werge, Thomas & Andreassen, O. A., 2009, In: Psychiatry Research. 168, 3, p. 256-8 2 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia with Risk for Depression in the Danish Population

Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Andreassen, O., Pedersen, C. B., Pedersen, M. G., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Agerbo, E., 2019, In: JAMA Psychiatry. 76, 5, p. 516-525 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Mcintosh, A. M., Whalley, H. C., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 216 others, Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S., Bækvad-hansen, M., Beekman, A. T. F., Bigdeli, T. B., Binder, E. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. R. I., Colodro-conde, L., Couvy-duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-price, V., Hassan Kiadeh, F. F., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J., Hougaard, D. M., Ising, M., Jansen, R., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Li, Y., Lind, P. A., Macintyre, D. J., Mackinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., Mcgrath, P., Mcguffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O'reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van Der Auwera, S., Van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., De Geus, E. J. C., Depaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., Mcintosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-myhsok, B., Nordentoft, Merete, Nöthen, M. M., O'donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, Thomas, Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P., Furlotte, N. A., Hinds, D. A., Huber, K. E., Kleinman, A., Litterman, N. K., Mccreight, J. C., Mcintyre, M. H., Mountain, J. L., Noblin, E. S., Northover, C. A. M., Pitts, S. J., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Shringarpure, S., Tian, C., Tung, J. Y., Vacic, V. & Wilson, C. H., 2019, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction

Togsverd, M., Tanko, L. B., Bagger, Y. Z., Hansen, T., Qin, G., Christiansen, C., Rasmussen, H. B. & Werge, Thomas, 2008, In: Journal of Affective Disorders. 106, 1-2, p. 169-172 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 46 others, Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Cervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Del Zompo, M., DePaulo, J. R., Étain, B., Jamain, S., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Nordentoft, Merete, Werge, Thomas, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Wray, N. R., Ripke, S., Matthiesen, M., Agerbo, E., Bækvad-Hansen, M., Buttenschøn, H. N., Bybjerg-Grauholm, J., Grove, J., Hansen, C. S., Hansen, T. F., Hougaard, D. M., Krogh, J., Pedersen, C. B., Pedersen, M. G., Qvist, P., Thompson, W. K., Wang, Y., Weinsheimer, S. M., Mortensen, P. B., Christensen, J. V. & Børglum, A. D., 2021, In: Molecular Psychiatry. 26, p. 2457–2470 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of the 120-bp duplication in the dopamine D4 receptor gene and schizophrenia in a sample of Danish subjects

Olsen, L., Timm, S., Wang, August Gabriel, Søeby, K., Jakobsen, K. D., Clemmensen, S., Løkke, A., Fossum, M., Parnas, Josef, Hemmingsen, R. P. A., Rasmussen, H. B. & Werge, Thomas, 2005, In: Schizophrenia Research. 73, 1, p. 133-5 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression

Koefoed, P., Woldbye, D. P. D., Hansen, T. V. O., Eplov, L. F., Christiansen, S. H. O., Mors, O., Kessing, L. V., Werge, T., Kaipio, K., Pesonen, U., Fahmy, T., Mellerup, E. T., Jakobsen, K. D., Hansen, E. S., Knudsen, G. M., Bukh, J. D., Bock, C., Lindberg, C., Kristensen, A. S., Dam, H. & 6 others, Nordentoft, Merete, Als, T. D., Wang, A. G., Gether, Ulrik, Rehfeld, Jens Frederik & Bolwig, T. G., 23 Mar 2012, In: Acta Neuropsychiatrica. 24, 2, p. 81-90 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples

Kähler, A. K., Otnæss, M. K., Wirgenes, K. V., Hansen, T., Jönsson, E. G., Agartz, I., Hall, H., Werge, T., Morken, G., Mors, O., Mellerup, E., Dam, H., Koefoed, P., Melle, I., Steen, V. M., Andreassen, O. A., Djurovic, S., Kähler, A. K., Otnaess, M. K., Wirgenes, K. V. & 14 others, Hansen, T., Jönsson, E. G., Agartz, I., Hall, H., Werge, Thomas, Morken, G., Mors, O., Mellerup, E., Dam, H., Koefod, P., Melle, I., Steen, V. M., Andreassen, O. A. & Djurovic, S., 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 1, p. 86-96 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia

Carrera, N., Arrojo, M., Sanjuán, J., Ramos-Ríos, R., Paz, E., Suárez-Rama, J. J., Páramo, M., Agra, S., Brenlla, J., Martínez, S., Rivero, O., Collier, D. A., Palotie, A., Cichon, S., Nöthen, M. M., Rietschel, M., Rujescu, D., Stefansson, H., Steinberg, S., Sigurdsson, E. & 12 others, St Clair, D., Tosato, S., Werge, Thomas, Stefansson, K., González, J. C., Valero, J., Gutiérrez-Zotes, A., Labad, A., Martorell, L., Vilella, E., Carracedo, Á. & Costas, J., 2012, In: Biological Psychiatry. 71, 2, p. 169-77 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors

Krebs, M. D., Themudo, G. E., Benros, Michael Eriksen, Mors, O., Børglum, A. D., Hougaard, D., Mortensen, P. B., Nordentoft, Merete, Gandal, M. J., Fan, C. C., Geschwind, D. H., Schork, A. J., Werge, Thomas & Thompson, W. K., 2021, In: Nature Communications. 12, 12 p., 6617.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome

Vangkilde, A., Jepsen, J. M. R., Schmock, H., Olesen, C., Arnarsdóttir, S., Baaré, W. F. C., Plessen, K. J., Didriksen, M., Siebner, Hartwig Roman, Werge, Thomas & Olsen, L., 2016, In: Journal of Neurodevelopmental Disorders. 8, 13 p., 42.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study

Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Geschwind, D. H., Buil Demur, Alfonso Alberto, Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, Thomas & Ingason, A., 2023, In: The Lancet Psychiatry. 10, 2, p. 129-138 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

At-Risk Variant in TCF7L2 for Type II Diabetes Increases Risk of Schizophrenia

Hansen, T., Ingason, A., Djurovic, S., Melle, I., Fenger, M., Gustafsson, O., Jakobsen, K. D., Rasmussen, H. B., Tosato, S., Rietschel, M., Frank, J., Owen, M., Bonetto, C., Suvisaari, J., Thygesen, J. H., Pétursson, H., Lönnqvist, J., Sigurdsson, E., Giegling, I., Craddock, N. & 12 others, O'Donovan, M. C., Ruggeri, M., Cichon, S., Ophoff, R. A., Pietiläinen, O., Peltonen, L., Nöthen, M. M., Rujescu, D., St Clair, D., Collier, D. A., Andreassen, O. A. & Werge, Thomas, 1 Jul 2011, In: Biological Psychiatry. 70, 1, p. 59-63 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants

Satterstrom, F. K., Walters, R. K., Singh, T., Wigdor, E. M., Lescai, F., Demontis, D., Kosmicki, J. A., Grove, J., Stevens, C., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Palmer, D. S., Maller, J. B., Nordentoft, M., Mors, O., Robinson, E. B., Hougaard, D. M., Werge, T. M., Bo Mortensen, P., Neale, B. M. & 3 others, Børglum, A. D., Daly, M. J. & iPSYCH-Broad Consortium, I. C., 2019, In: Nature Neuroscience. 22, 12, p. 1961-1965

Research output: Contribution to journal › Journal article › Research › peer-review

BIOLOGICAL PREDICTORS OF PSYCHIATRIC TRAJECTORIES IN A DANISH POPULATION COHORT OF INDIVIDUALS WITH SCHIZOPHRENIA

Krebs, M., Themudo, G. E., Benros, Michael Eriksen, Werge, Thomas & Thompson, W., 2019, In: European Neuropsychopharmacology. 29, S5, p. S260-S260 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, Treutlein, J., Witt, S. H., Cichon, S., Kogevinas, M., Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pers, Tune H, Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Nordentoft, Merete, Werge, Thomas, Hansen, Thomas Folkmann, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Brain expressed microRNAs implicated in schizophrenia etiology

Hansen, T., Olsen, L., Lindow, M., Jakobsen, K. D., Ullum, H., Jonsson, E., Andreassen, O. A., Djurovic, S., Melle, I., Agartz, I., Hall, H., Timm, S., Wang, August Gabriel & Werge, Thomas, 2007, In: P L o S One. 2, 9, p. e873

Research output: Contribution to journal › Journal article › Research › peer-review

Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum

LaBianca, S., Pagsberg, Anne Katrine, Jakobsen, K. D., Demur, A. B., Bartalan, M., LaBianca, J. & Werge, Thomas, 2018, In: Journal of Autism and Developmental Disorders. 48, 10, p. 3629-3636 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

CACNA1C (rs1006737) is associated with schizophrenia

Nyegaard, M., Demontis, D., Foldager, L., Hedemand, A., Flint, T. J., Sørensen, K. M., Andersen, P. S., Nordentoft, Merete, Werge, Thomas, Pedersen, C. B., Hougaard, D. M., Mortensen, P. B., Mors, O. & Børglum, A. D., 1 Feb 2010, In: Molecular Psychiatry. 15, 2, p. 119-21 3 p.

Research output: Contribution to journal › Letter › Research › peer-review

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C. & 86 others, van der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, Thomas, Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z., 2017, In: Nature Communications. 8, 11 p., 744.

Research output: Contribution to journal › Journal article › Research › peer-review

COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark

Shen, Q., Joyce, E. E., Ebrahimi, O. V., Didriksen, M., Lovik, A., Sævarsdóttir, K. S., Magnúsdóttir, I., Mikkelsen, D. H., Unnarsdóttir, A. B., Hauksdóttir, A., Hoffart, A., Kähler, A. K., Thórdardóttir, E. B., Eythórsson, E., Frans, E. M., Tómasson, G., Ask, H., Hardardóttir, H., Jakobsdóttir, J., Lehto, K. & 12 others, Lu, L., Andreassen, O. A., Sullivan, P. F., Pálsson, R., Erikstrup, C., Ostrowski, Sisse Rye, Werge, Thomas, Aspelund, T., Pedersen, Ole Birger Vesterager, Johnson, S. U., Fang, F. & Valdimarsdóttir, U. A., 2023, In: The Lancet Regional Health - Europe. 35, 12 p., 100756.

Research output: Contribution to journal › Journal article › Research › peer-review

CYP2D6 Genotyping and Antipsychotic-Associated Extrapyramidal Adverse Effects in a Randomized Trial of Aripiprazole Versus Quetiapine Extended Release in Children and Adolescents, Aged 12-17 Years, With First Episode Psychosis

Rudå, Ditte, mfw347, mfw347, Decara, M. S., Klauber, D. G., Fagerlund, Birgitte, Møllegaard, J. R., Linnet, Kristian, Werge, Thomas, Correll, C. U., Fink-Jensen, Anders, Jürgens, Gesche & Pagsberg, Anne Katrine, 2021, In: Journal of Clinical Psychopharmacology. 41, 6, p. 667-672

Research output: Contribution to journal › Journal article › Research › peer-review

CYP2D6 genotype predicts antipsychotic side effects in schizophrenia inpatients: a retrospective matched case-control study

Kobylecki, C. J., Jakobsen, K. D., Hansen, T., Jakobsen, I. V., Rasmussen, H. B., Werge, Thomas, Kobylecki, C. J., Jakobsen, K. D., Hansen, T., Jakobsen, I. V., Rasmussen, H. B. & Werge, Thomas, 2009, In: Neuropsychobiology. 59, 4, p. 222-6 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Can Animal Models of Copy Number Variants That Predispose to Schizophrenia Elucidate Underlying Biology?

Forsingdal, A., Jørgensen, T. N., Olsen, L., Werge, Thomas, Didriksen, M. & Nielsen, J., 2019, In: Biological Psychiatry. 85, 1, p. 13-24 12 p.

Research output: Contribution to journal › Review › Research › peer-review

Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area

Kähler, A. K., Djurovic, S., Rimol, L. M., Brown, A. A., Athanasiu, L., Jönsson, E. G., Hansen, T., Gústafsson, O., Hall, H., Giegling, I., Muglia, P., Cichon, S., Rietschel, M., Pietiläinen, O. P. H., Peltonen, L., Bramon, E., Collier, D., St Clair, D., Sigurdsson, E., Petursson, H. & 8 others, Rujescu, D., Melle, I., Werge, Thomas, Steen, V. M., Dale, A. M., Matthews, R. T., Agartz, I. & Andreassen, O. A., 1 Jan 2011, In: Biological Psychiatry. 69, 1, p. 90-6 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cerebral small vessel disease genomics and its implications across the lifespan

Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S. P., Kumar, R. B., van den Akker, E. B., McWhirter, R. E., Trompet, S., Mishra, A. & 32 others, Saba, Y., Satizabal, C. L., Beaudet, G., Petit, L., Tsuchida, A., Zago, L., Schilling, S., Sigurdsson, S., Gottesman, R. F., Lewis, C. E., Aggarwal, N. T., Lopez, O. L., Smith, J. A., Valdés Hernández, M. C., van der Grond, J., Wright, M. J., Knol, M. J., Dörr, M., Thomson, R. J., Bordes, C., Le Grand, Q., Duperron, M. G., Smith, A. V., Niessen, W. J., Pers, Tune H, Ingason, A., Francke Christensen, A., Hansen, Thomas Folkmann, Werge, Thomas, Olesen, Jes, International Network against Thrombosis (INVENT) Consortium, I. N. A. T. (. C. & International Headache Genomics Consortium (IHGC), I. H. G. C. (., 2020, In: Nature Communications. 11, 1, 18 p., 6285.

Research output: Contribution to journal › Journal article › Research › peer-review

Cholesterol-induced protein sorting: an analysis of energetic feasibility

Lundbaek, J. A., Andersen, Ove, Werge, Thomas & Nielsen, C., 2003, In: Biophysical Journal. 84, 3, p. 2080-9 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study

Pan, M., Roe, J. M., Nudel, R., Schork, A. J., Iakunchykova, O., Fjell, A. M., Walhovd, K. B., Werge, Thomas, Chen, C., Benros, Michael Eriksen & Wang, Y., 2023, In: Translational Psychiatry. 13, 174.

Research output: Contribution to journal › Journal article › Research › peer-review

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., de Geus, E. J. C. & 31 others, Grabe, H. J., Hamilton, S. P., Jones, I., Jones, L. A., Knowles, J. A., Kutalik, Z., Levinson, D. F., Lewis, G., Lind, P. A., Lucae, S., Magnusson, P. K., McGuffin, P., McIntosh, A. M., Milaneschi, Y., Mors, O., Mostafavi, S., Müller-Myhsok, B., Pedersen, N. L., Penninx, B. W. J. H., Potash, J. B., Preisig, M., Ripke, S., Shi, J., Bækvad-Hansen, M., Hansen, C. S., Hansen, Thomas Folkmann, Pedersen, C. B., Pedersen, M. G., Nordentoft, Merete, Werge, Thomas & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2020, In: Biological Psychiatry. 87, 5, p. 419-430 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Clinical association to FKBP5 rs1360780 in patients with depression

Dam, H., Buch, J. O. D., Nielsen, A. B., Weikop, Pia, Werge, Thomas & Jørgensen, M. B., 2019, In: Psychiatric Genetics. 29, 6, p. 220-225 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study

Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Grove, J., Nordentoft, Merete, Børglum, A. D., Mortensen, P. B., Werge, Thomas, Melbye, M., Hougaard, D. M. & Christiansen, M., 2021, In: Journal of Neurodevelopmental Disorders. 13, 9 p., 19.

Research output: Contribution to journal › Journal article › Research › peer-review

Cognitive performance in elderly women: significance of the 19bp insertion/deletion polymorphism in the 5' flank of the dopamine beta-hydroxylase gene, educational level, body fat measures, serum triglyceride, alcohol consumption and age

Togsverd, M., Werge, Thomas, Tankó, L. B., Bagger, Y. Z., Qin, G. G., Hansen, T., Christiansen, C. & Rasmussen, H. B., 2007, In: International Journal of Geriatric Psychiatry. 22, 9, p. 883-9 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cohort Profile: The Danish Blood Donor Study

Erikstrup, C., Sørensen, E., Nielsen, K. R., Bruun, M. T., Petersen, M. S., Rostgaard, K., Thørner, L. W., Larsen, M., Mikkelsen, S., Dinh, K. M., Schwinn, M., Rigas, A. S., Didriksen, M., Dowsett, J., von Stemann, J. H., Brodersen, T., Paulsen, I. W., Hindhede, L., Sækmose, S. G., Kaspersen, K. A. & 10 others, Boldsen, J. K., Kjerulff, B., Werge, Thomas, Brunak, Søren, Banasik, Karina, Hansen, Thomas Folkmann, Ullum, H., Hjalgrim, Henrik, Ostrowski, Sisse Rye & Pedersen, Ole Birger Vesterager, 2023, In: International Journal of Epidemiology. 52, 3, p. e162-e171 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review