Thomas Werge

Clinical Professor

Department of Clinical Medicine
Nordre Ringvej 26-67, 2600 Glostrup
- Thomas.Mears.Werge@sund.ku.dk
- https://ikm.ku.dk/

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Psychiatry

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Combinations of SNPs Related to Signal Transduction in Bipolar Disorder
Koefoed, P., Andreassen, O. A., Bennike, B., Dam, H., Djurovic, S., Hansen, T., Jorgensen, M. B., Kessing, Lars Vedel, Melle, I., Møller, G. L., Mors, O., Werge, Thomas & Mellerup, Erling Thyge, 1 Aug 2011, In: P L o S One. 6, 8, p. e23812 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Watson, H. J., Thornton, L. M., Yilmaz, Z., Baker, J. H., Coleman, J. R. I., Adan, R. A. H., Alfredsson, L., Andreassen, O. A., Ask, H., Berrettini, W. H., Boehnke, M., Boehm, I., Boni, C., Buehren, K., Bulant, J., Burghardt, R., Chang, X., Cichon, S., Cone, R. D., Courtet, P. & 157 others, Crow, S., Crowley, J. J., Danner, U. N., de Zwaan, M., Dedoussis, G., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Djurovic, S., Dmitrzak-Weglarz, M., Docampo-Martinez, E., Duriez, P., Egberts, K., Ehrlich, S., Eriksson, J. G., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Fernández-Aranda, F., Fichter, M. M., Föcker, M., Foretova, L., Forstner, A. J., Frei, O., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacòs, M., Guillaume, S., Guo, Y., Hakonarson, H., Hauser, J., Havdahl, A., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Hinney, A., Hübel, C., Hudson, J. I., Imgart, H., Jamain, S., Janout, V., Jiménez-Murcia, S., Jones, I. R., Julià, A., Kalsi, G., Kaminská, D., Kaprio, J., Karhunen, L., Kas, M. J. H., Keel, P. K., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Klareskog, L., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Leboyer, M., Li, D., Lilenfeld, L., Lin, B., Lissowska, J., Luykx, J., Magistretti, P., Maj, M., Marsal, S., Marshall, C. R., Mattingsdal, M., Meulenbelt, I., Micali, Nadia, Mitchell, K. S., Monteleone, A. M., Monteleone, P., Myers, R., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Pantel, J., Papežová, H., Pinto, D., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ripke, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Scherag, A., Scherer, S. W., Schmidt, U., Scott, L. J., Seitz, J., Silén, Y., Šlachtová, L., Slagboom, P. E., Slof-Op ‘t Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Walton, E., Widen, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J. E., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, Thomas, Whiteman, D. C., Woodside, D. B., Gordon, S., Maguire, S., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M., Wade, T. D., Birgegård, A., Lichtenstein, P., Landén, M., Martin, N. G., Mortensen, P. B., Breen, G. & Bulik, C. M., 2022, In: Biological Psychiatry Global Open Science. 2, 4, p. 368-378 11 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Common Variants at VRK2 and TCF4 Conferring Risk of Schizophrenia
Irish Schizophrenia Genomics Consortium, I. S. G. C., GROUP, G. & Wellcome Trust Case Control Consortium, W. T. C. C. C., 26 Jul 2011, In: Human Molecular Genetics. 20, 20, p. 4076-4081
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., Carrera, N., Legge, S. E., Bishop, S., Cameron, D., Hamshere, M. L., Han, J., Hubbard, L., Lynham, A., Mantripragada, K., Rees, E., MacCabe, J. H., McCarroll, S. A., Baune, B. T., Breen, G., Byrne, E. M. & 51 others, Dannlowski, U., Eley, T. C., Hayward, C., Martin, N. G., McIntosh, A. M., Plomin, R., Porteous, D. J., Wray, N. R., Caballero, A., Geschwind, D. H., Huckins, L. M., Ruderfer, D. M., Santiago, E., Sklar, P., Stahl, E. A., Won, H., Agerbo, E., Als, T. D., Andreassen, O. A., Bækvad-Hansen, M., Mortensen, P. B., Pedersen, C. B., Børglum, A. D., Bybjerg-Grauholm, J., Djurovic, S., Durmishi, N., Pedersen, M. G., Golimbet, V., Grove, J., Hougaard, D. M., Mattheisen, M., Molden, E., Mors, O., Nordentoft, Merete, Pejovic-Milovancevic, M., Sigurdsson, E., Silagadze, T., Hansen, C. S., Stefansson, K., Stefansson, H., Steinberg, S., Tosato, S., Werge, Thomas, GERAD1 Consortium:, G. C., CRESTAR Consortium, C. C., Collier, D. A., Rujescu, D., Kirov, G., Owen, M. J., O'Donovan, M. C. & Walters, J. T. R., 2018, In: Nature Genetics. 50, p. 381-389
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Common variant at 16p11.2 conferring risk of psychosis
Steinberg, S., de Jong, S., Mattheisen, M., Costas, J., Demontis, D., Jamain, S., Pietiläinen, O. P. H., Lin, K., Papiol, S., Huttenlocher, J., Sigurdsson, E., Vassos, E., Giegling, I., Breuer, R., Fraser, G., Walker, N., Melle, I., Djurovic, S., Agartz, I., Tuulio-Henriksson, A. & 31 others, Suvisaari, J., Lönnqvist, J., Paunio, T., Olsen, L., Hansen, T. F., Ingason, A., Pirinen, M., Strengman, E., Hougaard, D. M., Orntoft, T., Didriksen, M., Hollegaard, M. V., Nordentoft, Merete, Abramova, L., Kaleda, V., Arrojo, M., Sanjuán, J., Arango, C., Etain, B., Bellivier, F., Méary, A., Schürhoff, F., Szoke, A., Ribolsi, M., Magni, V., Siracusano, A., Sperling, S., Rossner, M., Christiansen, C., Werge, Thomas & GROUP, G., Jan 2014, In: Molecular Psychiatry. 19, 1, p. 108-114 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Common variants conferring risk of schizophrenia
Stefansson, H., Ophoff, R. A., Steinberg, S., Andreassen, O. A., Cichon, S., Rujescu, D., Werge, T., Pietiläinen, O. P. H., Mors, O., Mortensen, P. B., Sigurdsson, E., Gustafsson, O., Nyegaard, M., Tuulio-Henriksson, A., Ingason, A., Hansen, T., Suvisaari, J., Lonnqvist, J., Paunio, T., Børglum, A. D. & 31 others, Hartmann, A., Fink-Jensen, A., Nordentoft, Merete, Hougaard, D., Norgaard-Pedersen, B., Böttcher, Y., Olesen, Jes, Breuer, R., Möller, H., Giegling, I., Rasmussen, Henrik Berg, Timm, S., Mattheisen, M., Bitter, I., Réthelyi, J. M., Magnusdottir, B. B., Sigmundsson, T., Olason, P., Masson, G., Gulcher, J. R., Haraldsson, M., Fossdal, R., Thorgeirsson, T. E., Thorsteinsdottir, U., Ruggeri, M., Tosato, S., Franke, B., Strengman, E., Kiemeney, L. A., Melle, I. & Genetic Risk and Outcome in Psychosis (GROUP), G. R. A. O. I. P. (., 6 Aug 2009, In: Nature. 460, 7256, p. 744-7 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia
Shi, Y., Li, Z., Xu, Q., Wang, T., Li, T., Shen, J., Zhang, F., Chen, J., Zhou, G., Ji, W., Li, B., Xu, Y., Liu, D., Wang, P., Yang, P., Liu, B., Sun, W., Wan, C., Qin, S., He, G. & 21 others, Steinberg, S., Cichon, S., Werge, Thomas, Sigurdsson, E., Tosato, S., Palotie, A., Nöthen, M. M., Rietschel, M., Ophoff, R. A., Collier, D. A., Rujescu, D., Clair, D. S., Stefansson, H., Stefansson, K., Ji, J., Wang, Q., Li, W., Zheng, L., Zhang, H., Feng, G. & He, L., Dec 2011, In: Nature Genetics. 43, 12, p. 1224-7 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comorbidities to restless legs syndrome – results from the Danish blood donor study
Didriksen, Maria, Hansen, T., Rigas, A., Allen, R., Burchell, B., Thørner, L., Nielsen, K., Di Angelantonio, E., Nielsen, M., Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, O., Paarup, H., Hjalgrim, H., Bruun, M., Burgdorf, K., Sørensen, E. & Ullum, H., 2017, In: Sleep Medicine. 40, Supplement 1, p. E79 1 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comorbidity of migraine with ADHD in adults
Hansen, Thomas Folkmann, Hoeffding, L. K., Kogelman, L., Haspang, T. M., Ullum, H., Sørensen, E., Erikstrup, C., Pedersen, O. B., Nielsen, K. R., Hjalgrim, H., Paarup, H. M., Werge, Thomas & Burgdorf, K., 2018, In: BMC Neurology. 18, 1, p. 1-9 147.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comparing Copy Number Variations in a Danish Case Cohort of Individuals with Psychiatric Disorders
Calle Sánchez, X., Helenius, D., Bybjerg-Grauholm, J., Pedersen, C., Hougaard, D. M., Børglum, A. D., Nordentoft, Merete, Mors, O., Mortensen, P. B., Geschwind, D. H., Montalbano, S., Raznahan, A., Thompson, W. K., Ingason, A. & Werge, Thomas, 2022, In: JAMA Psychiatry. 79, 1, p. 59-69
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Complement genes contribute sex-biased vulnerability in diverse disorders
Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., Taylor, K. E., Whelan, C. W., Tombleson, P., Loohuis, L. M. O., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H. & 33 others, Pers, Tune H, Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Hansen, M., Hansen, T., Li, T., Olsen, L., Pantelis, C., Rasmussen, H. B., Werge, Thomas, Su, Z., Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case–Control Consortium 2, W. T. C. C. 2., 2020, In: Nature. 582, 7813, p. 577-581 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes
Bybjerg-Grauholm, J., Hagen, C. M., Gonçalves, V. F., Bækvad-Hansen, M., Hansen, C. S., Hedley, P. L., Kanters, Jørgen K., Nielsen, J., Theisen, M., Mors, O., Kennedy, J., Als, T. D., Demur, A. B., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 13 Dec 2018, In: PLoS ONE. 13, 12, 26 p., e0208829.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci
Fadista, J., Skotte, L., Karjalainen, J., Abner, E., Sørensen, E., Ullum, H., Werge, Thomas, Esko, T., Milani, L., Palotie, A., Daly, M., Melbye, M., Feenstra, B., Geller, F., IPSYCH Grp, I. G. & FinnGen Consortium, F. C., 2022, In: Nature Communications. 13, 11 p., 3200.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., Gujral, M., Brandler, W. M., Malhotra, D., Wang, Z., Fuentes Fajarado, K. V., Maile, M. S., Ripke, S., Agartz, I., Albus, M., Alexander, M. & 34 others, Amin, F., Atkins, J., Bacanu, S. A., Belliveau, R. A., Bergen, S. E., Bertalan, M., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Bulik-Sullivan, B., Byerley, W., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Cheng, W., Hansen, M., Hansen, T., Olsen, L., Pers, T. H., Rasmussen, H. B., Werge, Thomas, Scherer, S. W., Neale, B. M., Sebat, J. & CNV and Schizophrenia Working Groups of the Psychiatric Genomics Consortium, C. A. S. W. G. O. T. P. G. C., 2017, In: Nature Genetics. 49, 1, p. 27-35
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Copy Number Variants and Polygenic Risk Scores Predict Need of Care in Autism and/or ADHD Families
LaBianca, S., LaBianca, J., Pagsberg, Anne Katrine, Jakobsen, K. D., Appadurai, V., Buil, A. & Werge, Thomas, Jan 2021, In: Journal of Autism and Developmental Disorders. 51, 1, p. 276-285 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Copy number variations in affective disorders and meta-analysis
Olsen, L., Hansen, T., Djurovic, S., Haastrup, E., Albrecthsen, A., Hoeffding, L. K. E., Secher, A., Gustafsson, O., Jakobsen, K. D., Nielsen, Finn Cilius, Ullum, H., Morken, G., Agartz, I., Melle, I., Gether, Ulrik, Andreassen, O. A. & Werge, Thomas, 2011, In: Psychiatric Genetics. 21, 6, p. 319-322 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Copy number variations of chromosome 16p13.1 region associated with schizophrenia
Ingason, A., Rujescu, D., Cichon, S., Sigurdsson, E., Sigmundsson, T., Pietiläinen, O. P. H., Buizer-Voskamp, J. E., Strengman, E., Francks, C., Muglia, P., Gylfason, A., Gustafsson, O., Olason, P. I., Steinberg, S., Hansen, T. F., Jakobsen, K. D., Rasmussen, H. B., Giegling, I., Möller, H-J., Hartmann, A. & 29 others, Crombie, C., Fraser, G., Walker, N., Lonnqvist, J., Suvisaari, J., Tuulio-Henriksson, A., Bramon, E., Kiemeney, L. A., Franke, B., Murray, R., Vassos, E., Toulopoulou, T., Mühleisen, T. W., Tosato, S., Ruggeri, M., Djurovic, S., Andreassen, O. A., Zhang, Z., Werge, Thomas, Ophoff, R. A., Rietschel, M., Nöthen, M. M., Petursson, H., Stefansson, H., Peltonen, L., Collier, D., Stefansson, K., St Clair, D. M. & GROUP Investigators, G. I., 1 Jan 2011, In: Molecular Psychiatry. 16, 1, p. 17-25 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Correlation between genetic and geographic structure in Europe
Lao, O., Lu, T. T., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A., Gether, U. & 13 others, Werge, Thomas, Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Gieger, C., Wichmann, H., Rüther, A., Schreiber, S., Becker, C., Nürnberg, P., Nelson, M. R., Krawczak, M. & Kayser, M., 2008, In: Current Biology. 18, 16, p. 1241-8 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Cross-trait assortative mating is widespread and inflates genetic correlation estimates
Border, R., Athanasiadis, G., Buil Demur, Alfonso Alberto, Schork, A. J., Cai, N., Young, A. I., Werge, Thomas, Flint, J., Kendler, K. S., Sankararaman, S., Dahl, A. W. & Zaitlen, N. A., 2022, In: Science. 378, 6621, p. 754-761 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells
Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.
Research output: Contribution to journal › Review › Research › peer-review
Published
D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 2012, In: European Archives of Psychiatry and Clinical Neuroscience. 262, 7, p. 549-56 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors
Hansen, T. F., Banasik, K., Erikstrup, C., Pedersen, O. B., Westergaard, D., Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, P., Andersen, S., Nyegaard, M., Jemec, G. B. E., Olesen, J., Werge, T., Johansson, P. I., Sørensen, E. & 3 others, Brunak, Søren, Ullum, H. & Burgdorf, Kristoffer Sølvsten, 9 Jun 2019, In: BMJ Open. 9, 6, p. 1-7 7 p., e028401.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder
Håvik, B., Degenhardt, F. A., Johansson, S., Fernandes, C. P. D., Hinney, A., Scherag, A., Lybæk, H., Djurovic, S., Christoforou, A., Ersland, K. M., Giddaluru, S., O'Donovan, M. C., Owen, M. J., Craddock, N., Mühleisen, T. W., Mattheisen, M., Schimmelmann, B. G., Renner, T., Warnke, A., Herpertz-Dahlmann, B. & 12 others, Sinzig, J., Albayrak, Ö., Rietschel, M., Nöthen, M. M., Bramham, C. R., Werge, Thomas, Hebebrand, J., Haavik, J., Andreassen, O. A., Cichon, S., Steen, V. M. & Le Hellard, S., 2012, In: P L o S One. 7, 4, p. e35424 12 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
DNA-methylation and immunological response in medication overuse headache
Carlsen, L. N., Hansen, C. S., Kogelman, L. J. A., Werge, Thomas, Ullum, H., Bybjerg-Grauholm, J., Hansen, Thomas Folkmann & Jensen, Rigmor Højland, 2023, In: Cephalalgia. 43, 3, p. 1-11
Research output: Contribution to journal › Journal article › Research › peer-review
Published
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
Jönsson, E. G., Saetre, P., Vares, M., Andreou, D., Larsson, K., Timm, S., Rasmussen, H. B., Djurovic, S., Melle, I., Andreassen, O. A., Agartz, I., Werge, T., Hall, H., Terenius, L., Jönsson, E. G., Saetre, P., Vares, M., Andreou, D., Larsson, K., Timm, S. & 8 others, Rasmussen, H. B., Djurovic, S., Melle, I., Andreassen, O. A., Agartz, I., Werge, Thomas, Hall, H. & Terenius, L., 2009, In: Neuropsychobiology. 59, 3, p. 142-50 8 p.
Research output: Contribution to journal › Journal article › Research › peer-review