Gastrointestinal complications after fast-track total hip and knee replacement: an observational study in a consecutive 36,932 patient cohort

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  • the Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group

Introduction: Gastrointestinal complications after total hip (THA) and knee arthroplasty (TKA) have been reported to be between 0.3 and 2.6% with bleeding and C. difficile infection in 0–1%, and 0.1–1.7%, respectively. The use of enhanced recovery or “fast-track” protocols have focused on optimizing all aspects of perioperative care resulting in reduced length of hospital stay (LOS) and potentially also gastrointestinal complications. This study is a detailed analysis on the occurrence of postoperative gastrointestinal complications resulting in increased hospital stay or readmissions in a large consecutive cohort of fast-track THA and TKA with complete 90 days follow-up. Materials and methods: This is an observational study on a consecutive cohort of primary unilateral THAs and TKAs performed between January 2010 and August 2017 in nine Danish high-volume fast-track centers. Discharge summaries and relevant patient records were reviewed in patients with readmissions within 90 days or LOS > 4 days caused by gastrointestinal complications. Results: The cohort included 36,932 patients with 58.3% females and 54.1% THAs. Mean age and BMI were 68 years and 28. Median postoperative LOS was 2 days. Only n: 276 (0.75 %) had a LOS > 4 days or a readmission within 90 days due to a gastrointestinal complication (CI 0.67%–0.84%). Of these, only 34 (0.09%) were graded as severe ileus or gastrointestinal bleeding. Conclusions: The risk of GI-complications within the first 90 postoperative days after fast-track THA and TKA was low (0.75%).

Original languageEnglish
JournalArchives of Orthopaedic and Trauma Surgery
Volume143
Issue number10
Pages (from-to)6033-6038
Number of pages6
ISSN0936-8051
DOIs
Publication statusPublished - Oct 2023

Bibliographical note

Funding Information:
The Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group. Frank Madsen (Department of Orthopedics, Aarhus University Hospital, Aarhus, Denmark), Torben Bæk Hansen (Department of Orthopedics, Regional Hospital Holstebro and University of Aarhus, Holstebro, Denmark), Kirill Gromov (Department of Orthopedics, Hvidovre Hospital, Hvidovre, Denmark), Lars Tambour Hansen (Department of Orthopedics, Sydvestjysk Hospital Esbjerg/Grindsted, Grindsted, Denmark), Claus Varnum (Department of Orthopedics, Vejle Hospital, Vejle, Denmark), Mikkel Rathsach Andersen (Department of Orthopedics, Gentofte University Hospital, Copenhagen, Denmark), Niels Harry Krarup (Department of Orthopedics, Viborg Hospital, Viborg, Denmark) & Søren Overgaard (Department of Orthopedic Surgery, Copenhagen University Hospital Bispebjerg, Copenhagen, NV, Denmark).

Publisher Copyright:
© 2023, The Author(s).

    Research areas

  • C. difficile, Fast-track, GI-bleed, GI-complications, POI, THA, TKA

ID: 371465270