Differential effect of extracellular calcium on the Na(+)-K+ pump activity in intact polymorphonuclear leucocytes and erythrocytes

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Standard

Differential effect of extracellular calcium on the Na(+)-K+ pump activity in intact polymorphonuclear leucocytes and erythrocytes. / Petersen, R H; Knudsen, T; Johansen, T.

In: FEBS Letters, Vol. 279, No. 1, 11.02.1991, p. 153-6.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Petersen, RH, Knudsen, T & Johansen, T 1991, 'Differential effect of extracellular calcium on the Na(+)-K+ pump activity in intact polymorphonuclear leucocytes and erythrocytes', FEBS Letters, vol. 279, no. 1, pp. 153-6. https://doi.org/10.1016/0014-5793(91)80272-5

APA

Petersen, R. H., Knudsen, T., & Johansen, T. (1991). Differential effect of extracellular calcium on the Na(+)-K+ pump activity in intact polymorphonuclear leucocytes and erythrocytes. FEBS Letters, 279(1), 153-6. https://doi.org/10.1016/0014-5793(91)80272-5

Vancouver

Petersen RH, Knudsen T, Johansen T. Differential effect of extracellular calcium on the Na(+)-K+ pump activity in intact polymorphonuclear leucocytes and erythrocytes. FEBS Letters. 1991 Feb 11;279(1):153-6. https://doi.org/10.1016/0014-5793(91)80272-5

Author

Petersen, R H ; Knudsen, T ; Johansen, T. / Differential effect of extracellular calcium on the Na(+)-K+ pump activity in intact polymorphonuclear leucocytes and erythrocytes. In: FEBS Letters. 1991 ; Vol. 279, No. 1. pp. 153-6.

Bibtex

@article{4bfeff122df2419ca90ec2899e2ac928,
title = "Differential effect of extracellular calcium on the Na(+)-K+ pump activity in intact polymorphonuclear leucocytes and erythrocytes",
abstract = "The effect of extracellular calcium on the Na(+)-K+ pump activity in human polymorphonuclear leucocytes and erythrocytes was studied and compared with the activity in mixed peritoneal leucocytes from rats. While there was maximal decrease in the pump activity (25-30%) of leucocytes from both rat and human by calcium 0.6 mM, a concentration of 0.1 mM caused a substantial decrease indicating a high sensitivity for extracellular calcium. In contrast, calcium had no effect on the pump activity in erythrocytes. The effect of calcium on the pump activity in leucocytes may be due to regulation of the influx of sodium across the plasma membrane, since in human leucocytes calcium had no effect on the pump activity if the cells were loaded with sodium.",
keywords = "Animals, Calcium/pharmacology, Carrier Proteins/drug effects, Erythrocytes/metabolism, Humans, Male, Membrane Proteins/metabolism, Neutrophils/metabolism, Potassium/metabolism, Rats, Rats, Inbred Strains, Sodium/metabolism, Sodium-Potassium-Chloride Symporters",
author = "Petersen, {R H} and T Knudsen and T Johansen",
year = "1991",
month = feb,
day = "11",
doi = "10.1016/0014-5793(91)80272-5",
language = "English",
volume = "279",
pages = "153--6",
journal = "F E B S Letters",
issn = "0014-5793",
publisher = "JohnWiley & Sons Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Differential effect of extracellular calcium on the Na(+)-K+ pump activity in intact polymorphonuclear leucocytes and erythrocytes

AU - Petersen, R H

AU - Knudsen, T

AU - Johansen, T

PY - 1991/2/11

Y1 - 1991/2/11

N2 - The effect of extracellular calcium on the Na(+)-K+ pump activity in human polymorphonuclear leucocytes and erythrocytes was studied and compared with the activity in mixed peritoneal leucocytes from rats. While there was maximal decrease in the pump activity (25-30%) of leucocytes from both rat and human by calcium 0.6 mM, a concentration of 0.1 mM caused a substantial decrease indicating a high sensitivity for extracellular calcium. In contrast, calcium had no effect on the pump activity in erythrocytes. The effect of calcium on the pump activity in leucocytes may be due to regulation of the influx of sodium across the plasma membrane, since in human leucocytes calcium had no effect on the pump activity if the cells were loaded with sodium.

AB - The effect of extracellular calcium on the Na(+)-K+ pump activity in human polymorphonuclear leucocytes and erythrocytes was studied and compared with the activity in mixed peritoneal leucocytes from rats. While there was maximal decrease in the pump activity (25-30%) of leucocytes from both rat and human by calcium 0.6 mM, a concentration of 0.1 mM caused a substantial decrease indicating a high sensitivity for extracellular calcium. In contrast, calcium had no effect on the pump activity in erythrocytes. The effect of calcium on the pump activity in leucocytes may be due to regulation of the influx of sodium across the plasma membrane, since in human leucocytes calcium had no effect on the pump activity if the cells were loaded with sodium.

KW - Animals

KW - Calcium/pharmacology

KW - Carrier Proteins/drug effects

KW - Erythrocytes/metabolism

KW - Humans

KW - Male

KW - Membrane Proteins/metabolism

KW - Neutrophils/metabolism

KW - Potassium/metabolism

KW - Rats

KW - Rats, Inbred Strains

KW - Sodium/metabolism

KW - Sodium-Potassium-Chloride Symporters

U2 - 10.1016/0014-5793(91)80272-5

DO - 10.1016/0014-5793(91)80272-5

M3 - Journal article

C2 - 1995336

VL - 279

SP - 153

EP - 156

JO - F E B S Letters

JF - F E B S Letters

SN - 0014-5793

IS - 1

ER -

ID: 226261161