Early pleural fluid dynamics following video-assisted thoracoscopic lobectomy has limited clinical value
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Early pleural fluid dynamics following video-assisted thoracoscopic lobectomy has limited clinical value. / Holbek, Bo Laksáfoss; Petersen, René Horsleben; Kehlet, Henrik; Hansen, Henrik Jessen.
In: Journal of Thoracic Disease, Vol. 9, No. 7, 07.2017, p. 2204-2208.Research output: Contribution to journal › Letter › Research › peer-review
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TY - JOUR
T1 - Early pleural fluid dynamics following video-assisted thoracoscopic lobectomy has limited clinical value
AU - Holbek, Bo Laksáfoss
AU - Petersen, René Horsleben
AU - Kehlet, Henrik
AU - Hansen, Henrik Jessen
PY - 2017/7
Y1 - 2017/7
N2 - The objective of this study was to evaluate the potential of predicting the pleural fluid output in patients after video-assisted thoracoscopic lobectomy of the lung. Detailed measurements of continuous fluid output were obtained prospectively using an electronic thoracic drainage device (Thopaz+™, Medela AG, Switzerland). Patients were divided into high (≥500 mL) and low (<500 mL) 24-hour fluid output, and detailed flow curves were plotted graphically to identify arithmetic patterns predicting fluid output in the early (≤24 hours) and later (24-48 hours) post-operative phase. Furthermore, multiple logistic regression analysis was used to predict high 24-hour fluid output using baseline data. Data were obtained from 50 patients, where 52% had a fluid output of <500 mL/24 hours. From visual assessment of flow curves, patients were grouped according to fluid output 6 hours postoperatively. An output ≥200 mL/6 hours was predictive of 'high 24-hour fluid output' (P<0.0001). However, 33% of patients with <200 mL/6 hours ended with a 'high 24-hour fluid output'. Baseline data showed no predictive value of fluid production, and 24-hour fluid output had no predictive value of fluid output between 24 and 48 hours. Assessment of initial fluid production may predict high 24-hour fluid output (≥500 mL) but seems to lack clinical value in drain removal criteria.
AB - The objective of this study was to evaluate the potential of predicting the pleural fluid output in patients after video-assisted thoracoscopic lobectomy of the lung. Detailed measurements of continuous fluid output were obtained prospectively using an electronic thoracic drainage device (Thopaz+™, Medela AG, Switzerland). Patients were divided into high (≥500 mL) and low (<500 mL) 24-hour fluid output, and detailed flow curves were plotted graphically to identify arithmetic patterns predicting fluid output in the early (≤24 hours) and later (24-48 hours) post-operative phase. Furthermore, multiple logistic regression analysis was used to predict high 24-hour fluid output using baseline data. Data were obtained from 50 patients, where 52% had a fluid output of <500 mL/24 hours. From visual assessment of flow curves, patients were grouped according to fluid output 6 hours postoperatively. An output ≥200 mL/6 hours was predictive of 'high 24-hour fluid output' (P<0.0001). However, 33% of patients with <200 mL/6 hours ended with a 'high 24-hour fluid output'. Baseline data showed no predictive value of fluid production, and 24-hour fluid output had no predictive value of fluid output between 24 and 48 hours. Assessment of initial fluid production may predict high 24-hour fluid output (≥500 mL) but seems to lack clinical value in drain removal criteria.
KW - Journal Article
U2 - 10.21037/jtd.2017.06.107
DO - 10.21037/jtd.2017.06.107
M3 - Letter
C2 - 28840021
VL - 9
SP - 2204
EP - 2208
JO - Journal of Thoracic Disease
JF - Journal of Thoracic Disease
SN - 2072-1439
IS - 7
ER -
ID: 185371953