Praktisk anvendelse af thiopuriner hos patienter med kronisk inflammatoriske tarmsygdomme
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Praktisk anvendelse af thiopuriner hos patienter med kronisk inflammatoriske tarmsygdomme. / Zhao, Mirabella; Wewer, Mads Damsgaard; Bjerrum, Jacob Tveiten; Steenholdt, Casper; Schiødt, Frank; Haderslev, Kent; Kiszka-Kanowitz, Marianne; Munkholm, Pia; Seidelin, Jakob; Burisch, Johan.
In: Ugeskrift for Laeger, Vol. 184, No. 11, V09210706, 2022.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Praktisk anvendelse af thiopuriner hos patienter med kronisk inflammatoriske tarmsygdomme
AU - Zhao, Mirabella
AU - Wewer, Mads Damsgaard
AU - Bjerrum, Jacob Tveiten
AU - Steenholdt, Casper
AU - Schiødt, Frank
AU - Haderslev, Kent
AU - Kiszka-Kanowitz, Marianne
AU - Munkholm, Pia
AU - Seidelin, Jakob
AU - Burisch, Johan
PY - 2022
Y1 - 2022
N2 - Despite the increasing availability of biological treatment in recent years, thiopurines remain an important treatment option in patients with inflammatory bowel diseases (IBD) both as monotherapy and in combination therapy with biologicals. Pre-treatment screening of thiopurine-methyltransferase activity and monitoring of thiopurine metabolites during treatment are essential to optimize the effectiveness and safety of thiopurines. This review provides an evidence-based practical guide to prescribing and monitoring thiopurines in patients with IBD.
AB - Despite the increasing availability of biological treatment in recent years, thiopurines remain an important treatment option in patients with inflammatory bowel diseases (IBD) both as monotherapy and in combination therapy with biologicals. Pre-treatment screening of thiopurine-methyltransferase activity and monitoring of thiopurine metabolites during treatment are essential to optimize the effectiveness and safety of thiopurines. This review provides an evidence-based practical guide to prescribing and monitoring thiopurines in patients with IBD.
M3 - Review
C2 - 35315759
AN - SCOPUS:85126837588
VL - 184
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 11
M1 - V09210706
ER -
ID: 344374630