Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury

Research output: Contribution to journal › Journal article › Research › peer-review

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Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury. / Ashina, Håkan; Al-Khazali, Haidar Muhsen; Iljazi, Afrim; Ashina, Sait; Amin, Faisal Mohammad; Lipton, Richard B.; Schytz, Henrik Winther.

In: Journal of Headache and Pain, Vol. 22, 83, 2021.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Ashina, H, Al-Khazali, HM, Iljazi, A, Ashina, S, Amin, FM, Lipton, RB & Schytz, HW 2021, 'Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury', Journal of Headache and Pain, vol. 22, 83. https://doi.org/10.1186/s10194-021-01287-7

APA

Ashina, H., Al-Khazali, H. M., Iljazi, A., Ashina, S., Amin, F. M., Lipton, R. B., & Schytz, H. W. (2021). Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury. Journal of Headache and Pain, 22, [83]. https://doi.org/10.1186/s10194-021-01287-7

Vancouver

Ashina H, Al-Khazali HM, Iljazi A, Ashina S, Amin FM, Lipton RB et al. Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury. Journal of Headache and Pain. 2021;22. 83. https://doi.org/10.1186/s10194-021-01287-7

Author

Ashina, Håkan ; Al-Khazali, Haidar Muhsen ; Iljazi, Afrim ; Ashina, Sait ; Amin, Faisal Mohammad ; Lipton, Richard B. ; Schytz, Henrik Winther. / Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury. In: Journal of Headache and Pain. 2021 ; Vol. 22.

Bibtex

@article{f1fbaa66c3774ba0ac4f80650d3c775a,

title = "Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury",

abstract = "Objective: To investigate the association of psychiatric and cognitive comorbidities with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (TBI). Methods: A total of 100 patients with persistent PTH attributed to mild TBI and 100 age- and gender-matched healthy controls free of mild TBI were enrolled between July 2018 and June 2019. Quality of sleep was evaluated using the Pittsburgh Sleep Quality Index, while symptoms of anxiety and depression were assessed using the Hospital Anxiety and Depression Scale. Cognitive impairment was evaluated using the Montreal Cognitive Assessment questionnaire, while post-traumatic stress disorder (PTSD) was assessed using the Harvard Trauma Questionnaire. Results: In 100 patients with persistent PTH, 85% reported poor quality sleep, compared with 42% of healthy controls (P < 0.01). The relative frequency of probable to high risk of anxiety was 52% in the persistent PTH group vs. 8% in healthy controls (P < 0.01), while the relative frequency of probable to high risk of depression was 42% in the persistent PTH group vs. 2% in healthy controls (P < 0.01). Furthermore, 27% of the patients with persistent PTH had mild cognitive impairment while 10% had probable PTSD. Conclusions: Poor quality of sleep as well as symptoms suggestive of anxiety and depression were more common in patients with persistent PTH than healthy controls. Clinicians should screen patients with persistent PTH for these comorbidities and develop treatment plans that account for their presence.",

keywords = "Anxiety, Cognitive impairment, Depression, Post-traumatic stress disorder, Sleep",

author = "H{\aa}kan Ashina and Al-Khazali, {Haidar Muhsen} and Afrim Iljazi and Sait Ashina and Amin, {Faisal Mohammad} and Lipton, {Richard B.} and Schytz, {Henrik Winther}",

note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",

year = "2021",

doi = "10.1186/s10194-021-01287-7",

language = "English",

volume = "22",

journal = "Journal of Headache and Pain",

issn = "1129-2369",

publisher = "Springer",

}

RIS

TY - JOUR

T1 - Psychiatric and cognitive comorbidities of persistent post-traumatic headache attributed to mild traumatic brain injury

AU - Ashina, Håkan

AU - Al-Khazali, Haidar Muhsen

AU - Iljazi, Afrim

AU - Ashina, Sait

AU - Amin, Faisal Mohammad

AU - Lipton, Richard B.

AU - Schytz, Henrik Winther

PY - 2021

Y1 - 2021

N2 - Objective: To investigate the association of psychiatric and cognitive comorbidities with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (TBI). Methods: A total of 100 patients with persistent PTH attributed to mild TBI and 100 age- and gender-matched healthy controls free of mild TBI were enrolled between July 2018 and June 2019. Quality of sleep was evaluated using the Pittsburgh Sleep Quality Index, while symptoms of anxiety and depression were assessed using the Hospital Anxiety and Depression Scale. Cognitive impairment was evaluated using the Montreal Cognitive Assessment questionnaire, while post-traumatic stress disorder (PTSD) was assessed using the Harvard Trauma Questionnaire. Results: In 100 patients with persistent PTH, 85% reported poor quality sleep, compared with 42% of healthy controls (P < 0.01). The relative frequency of probable to high risk of anxiety was 52% in the persistent PTH group vs. 8% in healthy controls (P < 0.01), while the relative frequency of probable to high risk of depression was 42% in the persistent PTH group vs. 2% in healthy controls (P < 0.01). Furthermore, 27% of the patients with persistent PTH had mild cognitive impairment while 10% had probable PTSD. Conclusions: Poor quality of sleep as well as symptoms suggestive of anxiety and depression were more common in patients with persistent PTH than healthy controls. Clinicians should screen patients with persistent PTH for these comorbidities and develop treatment plans that account for their presence.

AB - Objective: To investigate the association of psychiatric and cognitive comorbidities with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (TBI). Methods: A total of 100 patients with persistent PTH attributed to mild TBI and 100 age- and gender-matched healthy controls free of mild TBI were enrolled between July 2018 and June 2019. Quality of sleep was evaluated using the Pittsburgh Sleep Quality Index, while symptoms of anxiety and depression were assessed using the Hospital Anxiety and Depression Scale. Cognitive impairment was evaluated using the Montreal Cognitive Assessment questionnaire, while post-traumatic stress disorder (PTSD) was assessed using the Harvard Trauma Questionnaire. Results: In 100 patients with persistent PTH, 85% reported poor quality sleep, compared with 42% of healthy controls (P < 0.01). The relative frequency of probable to high risk of anxiety was 52% in the persistent PTH group vs. 8% in healthy controls (P < 0.01), while the relative frequency of probable to high risk of depression was 42% in the persistent PTH group vs. 2% in healthy controls (P < 0.01). Furthermore, 27% of the patients with persistent PTH had mild cognitive impairment while 10% had probable PTSD. Conclusions: Poor quality of sleep as well as symptoms suggestive of anxiety and depression were more common in patients with persistent PTH than healthy controls. Clinicians should screen patients with persistent PTH for these comorbidities and develop treatment plans that account for their presence.

KW - Anxiety

KW - Cognitive impairment

KW - Depression

KW - Post-traumatic stress disorder

KW - Sleep

U2 - 10.1186/s10194-021-01287-7

DO - 10.1186/s10194-021-01287-7

M3 - Journal article

C2 - 34311696

AN - SCOPUS:85111244520

VL - 22

JO - Journal of Headache and Pain

JF - Journal of Headache and Pain

SN - 1129-2369

M1 - 83

ER -

ID: 275882654