Mannose-Binding Lectin Deficiency Is Associated with Myocardial Infarction: The HUNT2 Study in Norway
Research output: Contribution to journal › Journal article › Research › peer-review
Mannose-binding lectin (MBL) and ficolins activate the complement cascade, which is involved in atherogenesis. Based on a pilot study, we hypothesized that functional polymorphisms in the MBL gene (MBL2) leading to dysfunctional protein are related to development of myocardial infarction (MI). The aim of the present study was to study polymorphisms in MBL2 and ficolin genes in relation to the risk of MI.
| Original language | English |
|---|---|
| Journal | P L o S One |
| Volume | 7 |
| Issue number | 7 |
| Pages (from-to) | e42113 |
| ISSN | 1932-6203 |
| DOIs | |
| Publication status | Published - 2012 |
ID: 48448976