Helle Krogh Johansen

Helle Krogh Johansen

Clinical Professor

Member of:

  • Clinical Microbiology


  1. Published

    Autoantibodies to pancreatic hsp60 precede the development of glucose intolerance in patients with cystic fibrosis

    Jensen, P., Johansen, Helle Krogh, Carmi, P., Høiby, Niels & Cohen, I. R., 2001, In: J. Autoimmunity. 17, p. 165-172

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Posttreatment Antifungal Resistance among Colonizing Candida Isolates in Candidemia Patients: Results from a Systematic Multicenter Study

    Jensen, R. H., Johansen, Helle Krogh, Søes, L. M., Lemming, L. E., Rosenvinge, F. S., Nielsen, L., Olesen, B., Kristensen, L., Dzajic, E., Astvad, K. M. T. & Arendrup, M. C., Mar 2016, In: Antimicrobial Agents and Chemotherapy. 60, 3, p. 1500-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

    Jensen, Ramon Gordon, Johansen, Helle Krogh, Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R. & Homøe, Preben, Jul 2017, In: European Archives of Oto-Rhino-Laryngology. 274, 7, p. 2741-2747 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia. A new prophylactic principle

    Johansen, Helle Krogh, Cryz, S. J., Hougen, H. P., Moser, Claus Ernst & Høiby, Niels, 1997, In: Behring Institute Mitteilungen. 98, p. 269-73 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Chronic Pseudomonas aeruginosa lung infection in normal and athymic rats

    Johansen, Helle Krogh, Espersen, F., Pedersen, S. S., Hougen, H. P., Rygaard, J. & Høiby, Niels, 1993, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 101, 3, p. 207-225 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Immunization with Pseudomonas aeruginosa vaccines and adjuvant can modulate the type of inflammatory response subsequent to infection

    Johansen, Helle Krogh, Espersen, F., Cryz, S. J., Hougen, H. P., Fomsgaard, A., Rygaard, J. & Høiby, Niels, 1994, In: Infection and Immunity. 62, 8, p. 3146-55 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Interferon-gamma (IFN-gamma) treatment decreases the inflammatory response in chronic Pseudomonas aeruginosa pneumonia in rats

    Johansen, Helle Krogh, Hougen, H. P., Rygaard, J. & Høiby, Niels, 1996, In: Clinical and Experimental Immunology. 103, 2, p. 212-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Vaccination promotes TH1-like inflammation and survival in chronic Pseudomonas aeruginosa pneumonia in rats

    Johansen, Helle Krogh, Hougen, H. P., Cryz, S. J., Rygaard, J. & Høiby, Niels, 1995, In: American Journal of Respiratory and Critical Care Medicine. 152, 4 Pt 1, p. 1337-46 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Klinisk bakteriologi, infektionshygiejne og antibiotikabehandling

    Johansen, H. K., Andersen, L. P., Skinhoj, P., Høiby, Niels & Johansen, Helle Krogh, 2008, Klinisk Mikrobiologi og Infektionsmedicin. 3rd ed. København: FADL's Forlag, Vol. 6. p. 223-298 75 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  10. Published

    Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

    Johansen, H. K., Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Cochrane Database of Systematic Reviews. 4, p. CD001399

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success? - A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection

    Johansen, Helle Krogh, Nørregaard, L., Gøtzsche, P. C., Pressler, T., Koch, C. & Høiby, Niels, 2004, In: Pediatric Pulmonology. 37, 5, p. 427-432

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Problems in the design and reporting of trials of antifungal agents encountered during meta-analysis

    Johansen, Helle Krogh & Gøtzsche, P. C., 1999, In: JAMA - Journal of the American Medical Association. 282, p. 1752-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Randomised trial of pivampicillin plus pivmecillinam vs. pivampicillin in children and young adults with chronic obstructive pulmonary disease and infection with Haemophilus influenzae

    Johansen, Helle Krogh, Børch, K., Espersen, F., Koch, C. & Høiby, Niels, 1999, In: Current Medical Research and Opinion. 15(4), p. 300-309

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Gene transcription profiles of paired mucoid & non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis

    Johansen, Helle Krogh, Wassermann, T., Alhede, M., Aanæs, Kasper, Buchwald, C. V. & Høiby, Niels, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  15. Published

    Amphotericin B lipid soluble formulations vs amphotericin B in cancer patients with neutropenia (Cochrane Review)

    Johansen, Helle Krogh & Gøtzsche, P. C., 2002, The Cochrane Library, Issue 2. Oxford: Update Software (updated), p. -

    Research output: Chapter in Book/Report/Conference proceedingReport chapterResearch

  16. Published

    Amphotericin B lipid soluble formulations versus amphotericin B in cancer patients with neutropenia

    Johansen, Helle Krogh & Gøtzsche, P. C., 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-30 30 p., CD000969.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients.

    Johansen, Helle Krogh, Moskowitz, S. M., Ciofu, Oana, Pressler, T. & Høiby, Niels, 2008, In: Journal of Cystic Fibrosis. 7, 5, p. 391-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

    Johansen, Helle Krogh & Gøtzsche, P. C., 2015, In: Cochrane Database of Systematic Reviews. 2015, 8, p. 1-19 19 p., CD001399.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response

    Johansen, Helle Krogh, Aanæs, Kasper, Pressler, T., Nielsen, Kim G., Fisker, J., Skov, M., Høiby, Niels & von Buchwald, Christian, Dec 2012, In: Journal of Cystic Fibrosis. 11, 6, p. 525-531 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Pseudomonas mendocina as a cause of chronic infective endocarditis in a patient with situs inversus

    Johansen, Helle Krogh, Kjeldsen, K. & Høiby, Niels, 2001, In: Clinical Microbiology and Infection. 7, p. 650-652

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients

    Johansen, Helle Krogh & Gøtzsche, P. C., 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-38 38 p., CD000239.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Har ny teknologi overflødiggjort Grams farvemetode? Dansk Selskab for Klinisk Mikrobiologi

    Johansen, Helle Krogh, Bjarnsholt, Thomas, Høiby, Niels & Dansk Selskab for Klinisk Mikrobiologi, D. S. F. K. M., 17 Mar 2008, In: Ugeskrift for læger. 170, 12, p. 1041

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Rat model of chronic Pseudomonas aeruginosa lung infection

    Johansen, Helle Krogh & Høiby, Niels, 1999, Handbook of animal models of infection. Academic Press, p. 517-526

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  24. Published

    Epidemic spread of Pandoraea apista, a new pathogen causing severe lung disease in cystic fibrosis patients

    Jorgensen, I. M., Johansen, Helle Krogh, Frederiksen, B., Pressler, T., Hansen, A., Vandamme, P., Høiby, Niels & Koch, C., 2003, In: Pediatric Pulmonology. 36(5), p. 439-446

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Flaws in design, analysis and interpretation of Pfizer's antifungal trials of voriconazole and uncritical subsequent quotations

    Jorgensen, K. J., Johansen, Helle Krogh & Gøtzsche, P. C., 2006, In: Trials. 7, p. Art no. 3-

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Voriconazole versus amphotericin B in cancer patients with neutropenia

    Jorgensen, K. J., Gøtzsche, P. C. & Johansen, Helle Krogh, 2006, In: Cochrane Database of Systematic Reviews. 1, p. Art no. CD004707-

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

    Jorgensen, K. M., Wassermann, T., Johansen, Helle Krogh, Christiansen, L. E., Molin, S., Høiby, Niels & Ciofu, Oana, Jul 2015, In: Microbiology. 161, 7, p. 1447-1462 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Epiglottitis with an abscess caused by Haemophilus parainfluenzae

    Juul, M. L., Johansen, Helle Krogh & Homøe, Preben, 17 Mar 2014, In: Ugeskrift for Laeger. 176, 12A, p. 2-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia

    Jørgensen, K. J., Gøtzsche, P. C., Dalbøge, C. S. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 2, p. 1-17 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination

    Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup, Pressler, T., Johansen, Helle Krogh & Kolpen, Mette, 2023, In: APMIS. 131, 8, p. 419-425

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Defining antimicrobial resistance in cystic fibrosis

    Kidd, T. J., Canton, R., Ekkelenkamp, M., Johansen, Helle Krogh, Gilligan, P., LiPuma, J. J., Bell, S. C., Elborn, J. S., Flume, P. A., VanDevanter, D. R., Waters, V. J. & Antimicrobial Resistance in Cystic Fibrosis International Working Group, A. R. I. C. F. I. W. G., 2018, In: Journal of Cystic Fibrosis. 17, 6, p. 696-704 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    A new device to prevent contamination of nasal swabs by Staphylococcus aureus in acute rhinosinutitis

    Kirkegaard Kiaer, E., Hakansson, K., Orntoft, S., Bartels, Mette Damkjær, Johansen, Helle Krogh & von Buchwald, Christian, 2020, In: Rhinology Online. 3, p. 39-44

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Active immunization against Staphylococcus aureus (oca+) periprosthetic osteomyelitis in rats

    Koch, J., Johansen, Helle Krogh, Vedel-Jensen, N., Jensen, A., poulsen, S. & Søe, H., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  34. Published

    Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution

    La Rosa, R., Johansen, Helle Krogh & Molin, S., 2022, In: Antibiotics. 11, 3, 419.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Compensatory evolution of Pseudomonas aeruginosa’s slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis

    La Rosa, R., Rossi, E., Feist, A. M., Johansen, Helle Krogh & Molin, S., 2021, In: Nature Communications. 12, 1, 3186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Convergent metabolic specialization through distinct evolutionary paths in Pseudomonas aeruginosa

    La Rosa, R., Johansen, Helle Krogh & Molina, S., 2018, In: mBio. 9, 2, 15 p., e00269-18.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients

    La Rosa, R., Johansen, Helle Krogh & Molin, S., 2019, In: Metabolites. 9, 10, 15 p., 234.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance

    Laborda, P., Lolle, S., Hernando-Amado, S., Alcalde-Rico, M., Aanæs, Kasper, Martínez, J. L., Molin, S. & Johansen, Helle Krogh, 2024, In: Nature Communications. 15, 1, 12 p., 2584.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Experimental chronic Pseudomonas aeruginosa lung infection in rats. Non-specific stimulation with LPS reduces lethality as efficiently as specific immunization

    Lange, Kai, Hougen, H. P., Høiby, Niels, Fomsgaard, A., Rygaard, J. & Johansen, Helle Krogh, 1995, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 103, 5, p. 367-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients

    Lauridsen, R. K., Sommer, L. M., Johansen, Helle Krogh, Rindzevicius, T., Molin, S., Jelsbak, L., Engelsen, Søren Balling & Boisen, A., 2017, In: Scientific Reports. 7, 7 p., 45264.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Linezolid in infective endocarditis - it seems to work

    Lauridsen, T., Bruun, L., Rasmussen, R., Moser, Claus Ernst, Johansen, Helle Krogh, Arpi, R. M., Hassager, Christian & Bruun, Niels Eske, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  42. Published

    High incidence of candidaemia in a nationwide cohort: Underlying diseases, risk factors and mortality

    Lausch, K. R., Søgaard, M., Rosenvinge, F. S., Johansen, Helle Krogh, jfn630, jfn630, Røder, B., Mortensen, K. L., Nielsen, L., Lemming, L., Olesen, B., Leitz, C., Kristensen, L., Dzajic, E., Østergaard, L., Schønheyder, H. C. & Arendrup, Maiken Cavling, 2018, In: International Journal of Infectious Diseases. 76, p. 58-63 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment

    Lausch, K. R., Søgaard, M., Rosenvinge, F. S., Johansen, Helle Krogh, jfn630, jfn630, Røder, B. L., Mortensen, K. L., Nielsen, L., Lemming, L., Olesen, B., Leitz, C., Kristensen, L., Dzajic, E., Østergaard, L. J., Schønheyder, H. C. & Arendrup, Maiken Cavling, 2018, In: Infection and Drug Resistance. 11, p. 2449-2459 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Emergence of ESBL-producing Klebsiella pneumoniae in Danish hospitals; this is in part explained by spread of one CTX-M-15 clone in Zealand

    Lester, C., Olsen, S., Arpi, R. M., Fuursted, K., Hansen, D. S., Heltberg, O., Holm, A., Højbjerg, T., Jensen, K., Johansen, Helle Krogh, Justesen, U., Kemp, M., Knudsen, I. J. D., Røder, B., Frimodt-Møller, N. & Hammerum, A., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  45. Published

    Clinical care of children with primary ciliary dyskinesia

    Lucas, J. S., Alanin, M. C., Collins, S., Harris, A., Johansen, Helle Krogh, Nielsen, Kim G., Papon, J. F., Robinson, P. & Walker, W. T., 2017, In: Expert Review of Respiratory Medicine. 11, 10, p. 779-790 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs

    Luján, A. M., Paterson, S., Hesse, E., Sommer, L. M., Marvig, R. L., Sharma, M. D., Alseth, E. O., Ciofu, Oana, Smania, A. M., Molin, S., Johansen, Helle Krogh & Buckling, A., 2022, In: Nature Ecology and Evolution. 6, p. 979–988

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa

    Markussen, T., Marvig, R. L., Gómez-Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., 2014, In: mBio. 5, 5, p. 1-10 10 p., e01592-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    International BEAT-PCD consensus statement for infection prevention and control for primary ciliary dyskinesia in collaboration with ERN-LUNG PCD Core Network and patient representatives

    Marthin, J. K., Lucas, J. S., Boon, M., Casaulta, C., Crowley, S., Destouches, D. M. S., Eber, E., Escribano, A., Haarman, E., Hogg, C., Maitre, B., Marsh, G., Martinu, V., Moreno-Galdó, A., Mussaffi, H., Omran, H., Pohunek, P., Rindlisbacher, B., Robinson, P., Snijders, D. & 4 others, Walker, W. T., Yiallouros, P., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: ERJ Open Research. 7, 3, 14 p., 00301-2021.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Mutations in 23S rRNA confer resistance against azithromycin in Pseudomonas aeruginosa

    Marvig, R. L., Søndergaard, M. S. R., Damkiær, S., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., Aug 2012, In: Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients

    Marvig, R. L., Dolce, D., Sommer, L. M., Petersen, Bent, Ciofu, Oana, Campana, S., Molin, S., Taccetti, G. & Johansen, Helle Krogh, 19 Oct 2015, In: B M C Microbiology. 15, 13 p., 218.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 8804