Helle Krogh Johansen

Helle Krogh Johansen

Clinical Professor

Member of:

  • Clinical Microbiology


Publication year:
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1 - 100 out of 204Page size: 100
  1. 2024
  2. Published

    Adaptive Evolution of Pseudomonas aeruginosa in Human Airways Shows Phenotypic Convergence Despite Diverse Patterns of Genomic Changes

    Espaillat, A., Colque, C. A., Rago, D., La Rosa, R., Molin, S. & Johansen, Helle Krogh, 2024, In: MOLECULAR BIOLOGY AND EVOLUTION . 41, 2, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance

    Laborda, P., Lolle, S., Hernando-Amado, S., Alcalde-Rico, M., Aanæs, Kasper, Martínez, J. L., Molin, S. & Johansen, Helle Krogh, 2024, In: Nature Communications. 15, 1, 12 p., 2584.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Predicting the primary infection source of Escherichia coli bacteremia using virulence-associated genes

    Ilsby, C. S., Hertz, Frederik Boëtius, Westh, Henrik T., Monk, J., Worning, P., Johansen, Helle Krogh, Hansen, Katrine Hartung & Pinholt, M., 2024, In: European Journal of Clinical Microbiology and Infectious Diseases. 43, 4, p. 641-648 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Ventriculostomy-associated infection (VAI) in patients with acute brain injury—a retrospective study

    Nielsen, P., Olsen, M. H., Willer-Hansen, R. S., Hauerberg, J., Johansen, Helle Krogh, Andersen, A. B., Knudsen, J. D. & Møller, Kirsten, 2024, In: Acta Neurochirurgica. 166, 1, 10 p., 128.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2023
  7. Published

    A Dedicated Mycosis Flask Increases the Likelihood of Identifying Candidemia Sepsis

    Ahlström, M. G., Antsupova, V. S., Pedersen, M., Johansen, Helle Krogh, Hansen, D. S. & Knudsen, I. J. D., 2023, In: Journal of Fungi. 9, 4, 15 p., 441.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Antimicrobial resistance of Pseudomonas aeruginosa in a cystic fibrosis population after introduction of a novel cephalosporin/β-lactamase inhibitor combination

    Katzenstein, T. L., Faurholt-Jepsen, D., Qvist, T., Jensen, Peter Østrup, Pressler, T., Johansen, Helle Krogh & Kolpen, Mette, 2023, In: APMIS. 131, 8, p. 419-425

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Inhalation devices and inhaled corticosteroids particle size influence on severe pneumonia in patients with chronic obstructive pulmonary disease: a nationwide cohort study

    Heerfordt, C. K., Rønn, C., Harboe, Zitta F B Barrella, Ingebrigtsen, T. S., Svorre Jordan, A., Wilcke, Jon Torgny Rostrup, Bonnesen, B., Biering-Sørensen, Tor, Sørensen, Rikke, Holler, J. G., Itenov, Theis Skovsgaard, Johansen, Helle Krogh, Sivapalan, P., Eklöf, J. & Jensen , Jens-Ulrik Stæhr , 2023, In: BMJ Open Respiratory Research. 10, 1, 10 p., e001814. .

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Long-term evolution of antibiotic tolerance in Pseudomonas aeruginosa lung  infections

    Ghoul, M., Andersen, Sandra Breum, Marvig, R. L., Johansen, Helle Krogh, Jelsbak, L., Molin, S., Perron, G. & Griffin, A. S., 2023, In: Evolution Letters. 7, 6, p. 389–400 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2022
  12. Published

    Achromobacter spp. in a Cohort of Non-Selected Pre-and Post-Lung Transplant Recipients

    Crone, C. G., Rezahosseini, O., Schultz, H. H. L., Qvist, T., Johansen, Helle Krogh, Nielsen, Susanne Dam & Perch, Michael, 2022, In: Pathogens. 11, 2, 181.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Diagnostic criteria of CNS infection in patients with external ventricular drainage after traumatic brain injury: a pilot study

    Willer-Hansen, R. S., Olsen, M. H., Hauerberg, J., Johansen, Helle Krogh, Andersen, Å. B. & Møller, Kirsten, 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 507-515 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Inter-species interactions alter antibiotic efficacy in bacterial communities

    Bottery, M. J., Matthews, J. L., Wood, A. J., Johansen, Helle Krogh, Pitchford, J. W. & Friman, V. P., 2022, In: ISME Journal. 16, p. 812–821

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams

    Colque, C. A., albarracín Orio, A. G., Tomatis, P. E., Dotta, G., Moreno, D. M., Hedemann, L. G., Hickman, R. A., Sommer, L. M., Feliziani, S., Moyano, A. J., Bonomo, R. A., Johansen, Helle Krogh, Molin, S., Vila, A. J. & Smania, A. M., 2022, In: mBio. 13, 5

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance

    Goltermann, L., Andersen, Kasper Langebjerg, Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1594-1601

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance: author's response

    Goltermann, L., Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1667-1668 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  18. Published

    New concepts in antimicrobial resistance in cystic fibrosis respiratory infections

    Drevinek, P., Canton, R., Johansen, Helle Krogh, Hoffman, L., Coenye, T., Burgel, P. & Davies, J. C., 2022, In: Journal of Cystic Fibrosis. 21, 6, p. 937-945 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease

    Eklöf, J., Misiakou, M. A., Sivapalan, P., Armbruster, K., Browatzki, A., Nielsen, T. L., Lapperre, T. S., Andreassen, H. F., Janner, J., Ulrik, C. S., Gabrielaite, M., Johansen, H. K., Jensen, A., Nielsen, T. V., Hertz, F. B., Ghathian, K., Calum, H., Wilcke, T., Seersholm, N., Jensen, J. U. S. & 1 others, Marvig, R. L., 2022, In: Clinical Microbiology and Infection. 28, 7, p. 990-995 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution

    La Rosa, R., Johansen, Helle Krogh & Molin, S., 2022, In: Antibiotics. 11, 3, 419.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs

    Luján, A. M., Paterson, S., Hesse, E., Sommer, L. M., Marvig, R. L., Sharma, M. D., Alseth, E. O., Ciofu, Oana, Smania, A. M., Molin, S., Johansen, Helle Krogh & Buckling, A., 2022, In: Nature Ecology and Evolution. 6, p. 979–988

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Topical niclosamide (ATx201) reduces Staphylococcus aureus colonization and increases Shannon diversity of the skin microbiome in atopic dermatitis patients in a randomized, double-blind, placebo-controlled Phase 2 trial

    Weiss, A., Delavenne, E., Matias, C., Lagler, H., Simon, D., Li, P., Hansen, J. U., Dos Santos, T. P., Jana, B., Priemel, P., Bangert, C., Bauer, M., Eberl, S., Nussbaumer-Pröll, A., Anne Österreicher, Z., Matzneller, P., Quint, T., Weber, M., Nielsen, H. M., Rades, T. & 17 others, Johansen, Helle Krogh, Westh, Henrik T., Kim, W., Mylonakis, E., Friis, C., Guardabassi, Luca, Pace, J., Lundberg, C. V., M'Zali, F., Butty, P., Sørensen, N., Nielsen, H. B., Toft-Kehler, R., Guttman-Yassky, E., Stingl, G., Zeitlinger, M. & Sommer, M., 2022, In: Clinical and Translational Medicine. 12, 5, e790.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Use of inhaled antibiotics among Danish patients with cystic fibrosis

    Møller, R., Nielsen, B. U., Faurholt-Jepsen, D., Katzenstein, T. L., Skov, M., Philipsen, L. K. D., Pressler, T., Johansen, Helle Krogh & Qvist, T., 2022, In: Pediatric Pulmonology. 57, 7, p. 1726-1734 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2021
  25. Published

    Achromobacter spp. genetic adaptation in cystic fibrosis

    Gabrielaite, M., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marvig, R. L., 2021, In: Microbial genomics. 7, 7, 13 p., 000582.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis

    Rossi, E., La Rosa, R., Bartell, J. A., Marvig, R. L., Haagensen, J. A. J., Sommer, L. M., Molin, S. & Johansen, Helle Krogh, 2021, In: Nature Reviews Microbiology. 19, p. 331–342

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19

    Backer, Vibeke, Sjöbring, U., Sonne, J., Weiss, A., Hostrup, Morten, Johansen, Helle Krogh, Becker, V., Sonne, D. P., Balchen, T., Jellingsø, M. & Sommer, M. O. A., 2021, In: The Lancet Regional Health - Europe. 4, 8 p., 100084.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A retrospective review of Achromobacter species and antibiotic treatments in patients with primary ciliary dyskinesia

    Holgersen, M. G., Marthin, J. K., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: Chronic Respiratory Disease. 18

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Adaptive interactions of achromobacter spp. With pseudomonas aeruginosa in cystic fibrosis chronic lung co-infection

    Sandri, A., Haagensen, J. A. J., Veschetti, L., Johansen, Helle Krogh, Molin, S., Malerba, G., Signoretto, C., Boaretti, M. & Lleo, M. M., 2021, In: Pathogens. 10, 8, 12 p., 978.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Bacterial re-colonization occurs early after lung transplantation in cystic fibrosis patients

    Holm, A. E., Schultz, H. H. L., Johansen, Helle Krogh, Pressler, T., Lund, T. K., Iversen, M. & Perch, Michael, 2021, In: Journal of Clinical Medicine. 10, 6, 11 p., 1275.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Co-delivery of ciprofloxacin and colistin using microcontainers for bacterial biofilm treatment

    Birk, S. E., Mazzoni, C., Mobasharah Javed, M., Borre Hansen, M., Johansen, Helle Krogh, Anders Juul Haagensen, J., Molin, S., Hagner Nielsen, L. & Boisen, A., 2021, In: International Journal of Pharmaceutics. 599, 120420.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Compensatory evolution of Pseudomonas aeruginosa’s slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis

    La Rosa, R., Rossi, E., Feist, A. M., Johansen, Helle Krogh & Molin, S., 2021, In: Nature Communications. 12, 1, 3186.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    High-throughput dilution-based growth method enables time-resolved exo-metabolomics of Pseudomonas putida and Pseudomonas aeruginosa

    Pedersen, B. H., Gurdo, N., Johansen, Helle Krogh, Molin, S., Nikel, P. I. & La Rosa, R., 2021, In: Microbial Biotechnology. 14, 5, p. 2214-2226

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    International BEAT-PCD consensus statement for infection prevention and control for primary ciliary dyskinesia in collaboration with ERN-LUNG PCD Core Network and patient representatives

    Marthin, J. K., Lucas, J. S., Boon, M., Casaulta, C., Crowley, S., Destouches, D. M. S., Eber, E., Escribano, A., Haarman, E., Hogg, C., Maitre, B., Marsh, G., Martinu, V., Moreno-Galdó, A., Mussaffi, H., Omran, H., Pohunek, P., Rindlisbacher, B., Robinson, P., Snijders, D. & 4 others, Walker, W. T., Yiallouros, P., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: ERJ Open Research. 7, 3, 14 p., 00301-2021.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Omics-based tracking of Pseudomonas aeruginosa persistence in "eradicated" cystic fibrosis patients

    Bartell, J. A., Sommer, L. M., Marvig, R. L., Skov, M., Pressler, T., Molin, S. & Johansen, Helle Krogh, 2021, In: The European Respiratory Journal. 57, 4, 2000512.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Transmission and Antibiotic Resistance of Achromobacter in Cystic Fibrosis

    Gabrielaite, M., Bartell, J. A., Nørskov-Lauritsen, N., Pressler, T., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marviga, R. L., 2021, In: Journal of Clinical Microbiology. 59, 4, e02911-20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Update 2016–2018 of the Nationwide Danish Fungaemia Surveillance Study: Epidemiologic Changes in a 15-Year Perspective

    Risum, M., Astvad, K., Johansen, Helle Krogh, Schønheyder, H. C., Rosenvinge, F., Knudsen, J. D., Hare, R. K., Datcu, R., Røder, B. L., Antsupova, V. S., Kristensen, L., Gertsen, J. B., Møller, J. K., Dzajic, E., Søndergaard, T. S. & Arendrup, Maiken Cavling, 2021, In: Journal of Fungi. 7, 6, 16 p., 491.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2020
  39. Published

    Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms

    Birk, S. E., Haagensen, J. A. J., Johansen, Helle Krogh, Molin, S., Nielsen, L. H. & Boisen, A., May 2020, In: Advanced Healthcare Materials. 9, 10, 10 p., 1901779.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Hypermutator Pseudomonas Aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients

    Colque, C. A., Albarracín Orio, A. G., Feliziani, S., Marvig, R. L., Tobares, A. R., Johansen, Helle Krogh, Molin, S. & Smania, A. M., Apr 2020, In: Antimicrobial Agents and Chemotherapy. 64, 5, p. e02142-19

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Nanograss sensor for selective detection of Pseudomonas aeruginosa by pyocyanin identification in airway samples

    Alatraktchi, F. A. Z. A., Dimaki, M., Støvring, N., Johansen, Helle Krogh, Molin, S. & Svendsen, W. E., Mar 2020, In: Analytical Biochemistry. 593, 6 p., 113586.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Hypermutation as an Evolutionary Mechanism for Achromobacter Xylosoxidans in Cystic Fibrosis Lung Infection

    Veschetti, L., Sandri, A., Johansen, Helle Krogh, Lleò, M. M. & Malerba, G., Feb 2020, In: Pathogens. 9, 2, 10 p., 72.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    A new device to prevent contamination of nasal swabs by Staphylococcus aureus in acute rhinosinutitis

    Kirkegaard Kiaer, E., Hakansson, K., Orntoft, S., Bartels, Mette Damkjær, Johansen, Helle Krogh & von Buchwald, Christian, 2020, In: Rhinology Online. 3, p. 39-44

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments

    Sommer, L. M., Johansen, Helle Krogh & Molin, S., 2020, In: Microbial Genomics. 6, 5, p. 1-6 6 p., 000370.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    Azole-Resistant Aspergillus fumigatus Among Danish Cystic Fibrosis Patients: Increasing Prevalence and Dominance of TR34/L98H

    Risum, M., Hare, R. K., Gertsen, J. B., Kristensen, L., Johansen, Helle Krogh, Helweg-Larsen, J., Abou-Chakra, N., Pressler, T., Skov, M., Jensen-Fangel, S. & Arendrup, Maiken Cavling, 2020, In: Frontiers in Microbiology. 11, 10 p., 1850.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment

    Bartell, J. A., Cameron, D. R., Mojsoska, B., Haagensen, J. A. J., Pressler, T., Sommer, L. M., Lewis, K., Molin, S. & Johansen, Helle Krogh, 2020, In: PLOS Pathogens. 16, 12 December, e1009112.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Gene loss and acquisition in lineages of pseudomonas aeruginosa evolving in cystic fibrosis patient airways

    Gabrielaite, M., Johansen, Helle Krogh, Molin, S., Nielsen, Finn Cilius & Marvig, R. L., 2020, In: mBio. 11, 5, p. 1-16 16 p., e02359-20.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

    Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.

    Research output: Contribution to journal › Letter › Research › peer-review

  49. 2019
  50. Published

    Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate

    Halfon, Y., Jimenez-Fernandez, A., La Rosa, R., Espinosa Portero, R., Johansen, Helle Krogh, Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S. & Yonath, A., 29 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22275-22281 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Adapting to the Airways: Metabolic Requirements of Pseudomonas aeruginosa during the Infection of Cystic Fibrosis Patients

    La Rosa, R., Johansen, Helle Krogh & Molin, S., 2019, In: Metabolites. 9, 10, 15 p., 234.

    Research output: Contribution to journal › Review › Research › peer-review

  52. Published

    Evolutionary highways to persistent bacterial infection

    Bartell, J. A., Sommer, L. M., Haagensen, J. A. J., Loch, A., Espinosa, R., Molin, S. & Johansen, Helle Krogh, 2019, In: Nature Communications. 10, 1, 13 p., 629.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis

    Burgener, E. B., Sweere, J. M., Bach, M. S., Secor, P. R., Haddock, N., Jennings, L. K., Marvig, R. L., Johansen, Helle Krogh, Rossi, E., Cao, X., Tian, L., Nedelec, L., Molin, S., Bollyky, P. L. & Milla, C. E., 2019, In: Science Translational Medicine. 11, 488, 12 p., eaau9748.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Reconciling Antimicrobial Susceptibility Testing and Clinical Response in Antimicrobial Treatment of Chronic Cystic Fibrosis Lung Infections

    Waters, V. J., Kidd, T. J., Canton, R., Ekkelenkamp, M. B., Johansen, Helle Krogh, LiPuma, J. J., Bell, S. C., Elborn, J. S., Flume, P. A., VanDevanter, D. R., Gilligan, P. & Antimicrobial Resistance International Working Group in Cystic Fibrosis , A. R. I. W. G. I. C. F., 2019, In: Clinical Infectious Diseases. 69, 10, p. 1812-1816

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. 2018
  56. Published

    Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia

    Scott, W. K., Medie, F. M., Ruffin, F., Sharma-Kuinkel, B. K., Cyr, D. D., Guo, S., Dykxhoorn, D. M., Skov, R. L., Bruun, N. E., Dahl, A., Lerche, C. J., Petersen, A., Larsen, A. R., Lauridsen, T. K., Johansen, H. K., Ullum, H., Sørensen, E., Hassager, C., Bundgaard, H., Schønheyder, H. C. & 9 others, Torp-Pedersen, C., Østergaard, L. B., Arpi, M., Rosenvinge, F., Erikstrup, L. T., Chehri, M., Søgaard, P., Andersen, P. S. & Fowler, V. G., Oct 2018, In: P L o S Genetics. 14, 10, p. 1-22 e1007667.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Human Genetic Susceptibility to Native Valve Staphylococcus aureus Endocarditis in Patients With S. aureus Bacteremia: Genome-Wide Association Study

    Moreau, K., Clemenceau, A., Le Moing, V., Messika-Zeitoun, D., Andersen, P. S., Bruun, Niels Eske, Skov, R. L., Couzon, F., Bouchiat, C., Erpelding, M. L., van Belkum, A., Bossé, Y., Duval, X., Vandenesch, F., The French VIRSTA-AEPEI, COFRASA Study Groups and the Danish DANSAB Study Group, T. F. V. C. S. G. A. T. D. D. S. G., Johansen, Helle Krogh, Hassager, Christian & Ullum, H., 4 Apr 2018, In: Frontiers in Microbiology. 9, p. 1-11 640.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Update from a 12-year nationwide fungemia surveillance: Increasing intrinsic and acquired resistance causes concern

    Astvad, K. M. T., Johansen, Helle Krogh, Røder, B. L., Rosenvinge, F. S., Knudsen, J. D., Lemming, L., Schønheyder, H. C., Hare, R. K., Kristensen, L., Nielsen, L., Gertsen, J. B., Dzajic, E., Pedersen, M., Østergård, C., Olesen, B., Søndergaard, T. S. & Arendrup, Maiken Cavling, 1 Apr 2018, In: Journal of Clinical Microbiology. 56, 4, 15 p., e01564.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Drug-Driven Phenotypic Convergence Supports Rational Treatment Strategies of Chronic Infections

    Imamovic, L., Ellabaan, M. M. H., Dantas Machado, A. M., Citterio, L., Wulff, T., Molin, S., Johansen, Helle Krogh & Sommer, M. O. A., 11 Jan 2018, In: Cell. 172, 1-2, p. 121-134.e14

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

    Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Convergent metabolic specialization through distinct evolutionary paths in Pseudomonas aeruginosa

    La Rosa, R., Johansen, Helle Krogh & Molina, S., 2018, In: mBio. 9, 2, 15 p., e00269-18.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Defining antimicrobial resistance in cystic fibrosis

    Kidd, T. J., Canton, R., Ekkelenkamp, M., Johansen, Helle Krogh, Gilligan, P., LiPuma, J. J., Bell, S. C., Elborn, J. S., Flume, P. A., VanDevanter, D. R., Waters, V. J. & Antimicrobial Resistance in Cystic Fibrosis International Working Group, A. R. I. C. F. I. W. G., 2018, In: Journal of Cystic Fibrosis. 17, 6, p. 696-704 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  63. Published

    High incidence of candidaemia in a nationwide cohort: Underlying diseases, risk factors and mortality

    Lausch, K. R., Søgaard, M., Rosenvinge, F. S., Johansen, Helle Krogh, jfn630, jfn630, Røder, B., Mortensen, K. L., Nielsen, L., Lemming, L., Olesen, B., Leitz, C., Kristensen, L., Dzajic, E., Østergaard, L., Schønheyder, H. C. & Arendrup, Maiken Cavling, 2018, In: International Journal of Infectious Diseases. 76, p. 58-63 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    High-resolution in situ transcriptomics of Pseudomonas aeruginosa unveils genotype independent patho-phenotypes in cystic fibrosis lungs

    Rossi, E., Falcone, M., Molin, S. & Johansen, Helle Krogh, 2018, In: Nature Communications. 9, 1, p. 1-13 3459.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts

    Frimodt-Møller, Jakob, Rossi, E., Haagensen, J. A. J., Falcone, M., Molin, S. & Johansen, Helle Krogh, 2018, In: Scientific Reports. 8, 1, p. 1-13 12512.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa

    Alatraktchi, F. A. Z. A., Noori, J. S., Tanev, G. P., Mortensen, J., Dimaki, M., Johansen, Helle Krogh, Madsen, J., Molin, S. & Svendsen, W. E., 2018, In: PLoS ONE. 13, 3, 9 p., e0194157.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Privatisation rescues function following loss of cooperation

    Andersen, Sandra Breum, Ghoul, M., Marvig, R. L., Lee, Z., Molin, S., Johansen, Helle Krogh & Griffin, A. S., 2018, In: eLife. 7, p. 1-27 27 p., e38594.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    The accessibility of topical treatment in the paranasal sinuses on operated cystic fibrosis patients assessed by scintigraphy

    Aanæs, Kasper, Alanin, M. C., Nielsen, Kim G., Jørgensen, M. M., von Buchwald, Christian, Høiby, N., Johansen, Helle Krogh, Johannesen, H. H. & Mortensen, Jann, 2018, In: Rhinology. 56, 3, p. 268-273

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    The small RNA ErsA of Pseudomonas aeruginosa contributes to biofilm development and motility through post-transcriptional modulation of AmrZ

    Falcone, M., Ferrara, S., Rossi, E., Johansen, Helle Krogh, Molin, S. & Bertoni, G., 2018, In: Frontiers in Microbiology. 9, FEB, 238.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Treatment of candidemia in a nationwide setting: increased survival with primary echinocandin treatment

    Lausch, K. R., Søgaard, M., Rosenvinge, F. S., Johansen, Helle Krogh, jfn630, jfn630, Røder, B. L., Mortensen, K. L., Nielsen, L., Lemming, L., Olesen, B., Leitz, C., Kristensen, L., Dzajic, E., Østergaard, L. J., Schønheyder, H. C. & Arendrup, Maiken Cavling, 2018, In: Infection and Drug Resistance. 11, p. 2449-2459 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. 2017
  72. Published

    Recurrent otorrhea in chronic suppurative otitis media: is biofilm the missing link?

    Jensen, Ramon Gordon, Johansen, Helle Krogh, Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R. & Homøe, Preben, Jul 2017, In: European Archives of Oto-Rhino-Laryngology. 274, 7, p. 2741-2747 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia

    Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, Kim G., Johansen, Helle Krogh & von Buchwald, Christian, Mar 2017, In: International Forum of Allergy Rhinology. 7, 3, p. 240-247

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats

    Søe, Niels Henrik, Jensen, N. V., Jensen, Asger Lundorff, Koch, J., Poulsen, Steen Seier, Pier, G. B. & Johansen, Helle Krogh, 2017, In: In Vivo. 31, 1, p. 45-50 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Clinical care of children with primary ciliary dyskinesia

    Lucas, J. S., Alanin, M. C., Collins, S., Harris, A., Johansen, Helle Krogh, Nielsen, Kim G., Papon, J. F., Robinson, P. & Walker, W. T., 2017, In: Expert Review of Respiratory Medicine. 11, 10, p. 779-790 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  76. Published

    Diversity, prevalence, and longitudinal occurrence of type II toxin-antitoxin systems of Pseudomonas aeruginosa infecting cystic fibrosis lungs

    Andersen, Sandra Breum, Ghoul, M., Griffin, A. S., Petersen, Bent, Johansen, Helle Krogh & Molin, S., 2017, In: Frontiers in Microbiology. 8, 12 p., 1180.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Is parotid saliva is sterile on entry to the oral cavity ?

    Schrøder, S., Jensen, A. B., Eickhardt-Dalbøge, S. R., Johansen, Helle Krogh & Homøe, Preben, 2017, In: Acta Oto-Laryngologica. 137, 7, p. 762-764 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients

    Lauridsen, R. K., Sommer, L. M., Johansen, Helle Krogh, Rindzevicius, T., Molin, S., Jelsbak, L., Engelsen, Søren Balling & Boisen, A., 2017, In: Scientific Reports. 7, 7 p., 45264.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. 2016
  80. Published

    Is genotyping of single isolates sufficient for population structure analysis of Pseudomonas aeruginosa in cystic fibrosis airways?

    Sommer, L. M., Marvig, R. L., Luján, A., Koza, A., Pressler, T., Molin, S. & Johansen, Helle Krogh, 9 Aug 2016, In: BMC Genomics. 17, 10 p., 589.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction

    Michelsen, C. F., Hossein Khademi, S. M., Johansen, Helle Krogh, Ingmer, Hanne, Dorrestein, P. C. & Jelsbak, L., Jun 2016, In: I S M E Journal. 10, 6, p. 1323-1336

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry

    Alatraktchi, F. A., Andersen, S. B., Johansen, Helle Krogh, Molin, S. & Svendsen, W. E., 19 Mar 2016, In: Sensors. 16, 3, 10 p., 408.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Posttreatment Antifungal Resistance among Colonizing Candida Isolates in Candidemia Patients: Results from a Systematic Multicenter Study

    Jensen, R. H., Johansen, Helle Krogh, Søes, L. M., Lemming, L. E., Rosenvinge, F. S., Nielsen, L., Olesen, B., Kristensen, L., Dzajic, E., Astvad, K. M. T. & Arendrup, M. C., Mar 2016, In: Antimicrobial Agents and Chemotherapy. 60, 3, p. 1500-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Bacterial evolution in PCD and CF patients follows the same mutational steps

    Sommer, L. M., Alanin, M. C., Marvig, R. L., Nielsen, Kim G., Høiby, Niels, von Buchwald, Christian, Molin, S. & Johansen, Helle Krogh, 2016, In: Scientific Reports. 6, 8 p., 28732.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease: Review

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2016, In: Cochrane Database of Systematic Reviews. 9, p. 1-27 27 p., CD007851.

    Research output: Contribution to journal › Review › Research › peer-review

  86. Published

    Sinus surgery postpones chronic gram-negative lung infection: Cohort study of 106 patients with cystic fibrosis

    Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, Helle Krogh & von Buchwald, Christian, 2016, In: Rhinology. 54, 3, p. 206-213 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. 2015
  88. Published

    A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia

    Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients

    Marvig, R. L., Dolce, D., Sommer, L. M., Petersen, Bent, Ciofu, Oana, Campana, S., Molin, S., Taccetti, G. & Johansen, Helle Krogh, 19 Oct 2015, In: B M C Microbiology. 15, 13 p., 218.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

    Jorgensen, K. M., Wassermann, T., Johansen, Helle Krogh, Christiansen, L. E., Molin, S., Høiby, Niels & Ciofu, Oana, Jul 2015, In: Microbiology. 161, 7, p. 1447-1462 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Antibiofilm Properties of Acetic Acid

    Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Mucosal biofilm detection in chronic otitis media: a study of middle ear biopsies from Greenlandic patients

    Wessman, M., Bjarnsholt, Thomas, Eickhardt-Sørensen, S. R., Johansen, Helle Krogh & Homøe, Preben, May 2015, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 272, 5, p. 1079-1085 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Monitoring meticillin resistant Staphylococcus aureus and its spread in Copenhagen, Denmark, 2013, through routine whole genome sequencing

    Bartels, Mette Damkjær, Larner-Svensson, H., Meiniche, H., Kristoffersen, K., Schønning, Kristian, Nielsen, J. B., Rohde, S. M., Christensen, L. B., Skibsted, A. W., Jarlov, J. O., Johansen, Helle Krogh, Andersen, L. P., Petersen, I. S., Crook, D. W., Bowden, R., Boye, K., Worning, P. & Westh, Henrik T., 30 Apr 2015, In: Eurosurveillance. 20, 17, 9 p., 21112.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia

    Alanin, M. C., Johansen, Helle Krogh, Aanaes, K., Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G. & von Buchwald, Christian, Jan 2015, In: Acta Oto-Laryngologica. 135, 1, p. 58-63 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Kompendium i mikrobiologi og infektionsmedicin

    Høiby, N., Skinhøj, P., Andersen, Å. B., Andersen, Leif Percival, Arendrup, M. C., Christiansen, C. B., Ciofu, Oana, Gerstoft, Jan, Johansen, Helle Krogh, Kemp, M., Kurtzhals, Jørgen, Nielsen, L. P., Lyngsøe Svejgaard, E., Theander, Thor Grundtvig & Thomsen, Allan Randrup, 2015, 1. ed. FADL's Forlag.

    Research output: Book/Report › Book › Education

  97. Published

    Long-term social dynamics drive loss of function in pathogenic bacteria

    Andersen, Sandra Breum, Marvig, R. L., Molin, S., Johansen, Helle Krogh & Griffin, A. S., 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 34, p. 10756-10761 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Vaccines for preventing infection with Pseudomonas aeruginosa in cystic fibrosis

    Johansen, Helle Krogh & Gøtzsche, P. C., 2015, In: Cochrane Database of Systematic Reviews. 2015, 8, p. 1-19 19 p., CD001399.

    Research output: Contribution to journal › Review › Research › peer-review

  99. 2014
  100. Published

    Comparing whole-genome sequencing with sanger sequencing for spa typing of methicillin-resistant staphylococcus aureus

    Bartels, Mette Damkjær, Petersen, A., Worning, P., Nielsen, J. B., Larner-Svensson, H., Johansen, Helle Krogh, Andersen, Leif Percival, Jarløv, J. O., Boye, K., Larsen, A. R. & Westh, Henrik T., 1 Dec 2014, In: Journal of clinical microbiology. 52, 12, p. 4305-4308 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Increasing prevalence of group B streptococcal infection among pregnant women

    Petersen, K. B., Johansen, Helle Krogh, Rosthøj, Susanne, Krebs, Lone, Pinborg, Anja & Hedegaard, M., Sep 2014, In: Danish Medical Journal. 61, 9, p. 1-5 5 p., A4908.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Epiglottitis with an abscess caused by Haemophilus parainfluenzae

    Juul, M. L., Johansen, Helle Krogh & Homøe, Preben, 17 Mar 2014, In: Ugeskrift for Laeger. 176, 12A, p. 2-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Amphotericin B lipid soluble formulations versus amphotericin B in cancer patients with neutropenia

    Johansen, Helle Krogh & Gøtzsche, P. C., 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-30 30 p., CD000969.

    Research output: Contribution to journal › Review › Research › peer-review

  104. Published

    Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients

    Johansen, Helle Krogh & Gøtzsche, P. C., 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-38 38 p., CD000239.

    Research output: Contribution to journal › Review › Research › peer-review

  105. Published

    Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa

    Markussen, T., Marvig, R. L., Gómez-Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, Niels, Johansen, Helle Krogh, Molin, S. & Jelsbak, L., 2014, In: mBio. 5, 5, p. 1-10 10 p., e01592-14.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    Nystatin prophylaxis and treatment in severely immunodepressed patients

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-23 23 p., CD002033.

    Research output: Contribution to journal › Review › Research › peer-review

  107. Published

    Routine versus selective antifungal administration for control of fungal infections in patients with cancer

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-48 48 p., CD000026.

    Research output: Contribution to journal › Review › Research › peer-review

  108. Published

    Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

    Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    Voriconazole versus amphotericin B or fluconazole in cancer patients with neutropenia

    Jørgensen, K. J., Gøtzsche, P. C., Dalbøge, C. S. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 2, p. 1-17 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  110. 2013
  111. Published

    P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs

    Ciofu, Oana, Johansen, Helle Krogh, Aanæs, Kasper, Wassermann, T., Alhede, M., von Buchwald, Christian & Høiby, Niels, 8 Mar 2013, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 12, 6, p. 729-736 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  112. Published

    A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF

    Dalbøge, C. S., Pressler, T., Høiby, Niels, Nielsen, Kim G. & Johansen, Helle Krogh, Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 42-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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