Filip Krag Knop
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Internal Medicine: Endocrinology
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Once-weekly GLP-1 agonists: How do they differ from exenatide and liraglutide?
Christensen, M. & Knop, Filip Krag, 1 Apr 2010, In: Current Diabetes Reports. 10, 2, p. 124-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of glucose-dependent insulinotropic polypeptide on glucagon
Christensen, M. & Knop, Filip Krag, Sep 2016, In: Cardiovascular Endocrinology. 5, 3, p. 75-81 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus
Christensen, M., Knop, Filip Krag, Holst, Jens Juul & Vilsboll, T., 2009, In: IDrugs. The Investigational Drugs Journal. 12, 8, p. 503-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The alpha-cell as target for type 2 diabetes therapy
Christensen, M., Bagger, J. I., Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Review of Diabetic Studies. 8, 3, p. 369-81 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption Independently of Insulin and Glycemia
Christensen, Mikkel Bring, Lund, A., Calanna, S., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2018, In: The Journal of clinical endocrinology and metabolism. 103, 1, p. 288-294Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes
Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GIP's involvement in the pathophysiology of type 2 diabetes
Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt, Heimbürger, S. M., Stensen, S., Vilsbøll, Tina & Knop, Filip Krag, Mar 2020, In: Peptides. 125, 10 p., 170178.Research output: Contribution to journal › Review › Research › peer-review
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Glucose-Dependent Insulinotropic Polypeptide (GIP) Reduces Bone Resorption in Patients With Type 2 Diabetes
Christensen, Mikkel Bring, Lund, A. B., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Journal of the endocrine society. 4, 9, 9 p., 097.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight Loss for Patients With Gout and Concomitant Obesity: A Proof-of-Concept Randomized Trial
Christensen, R., Zobbe, K., Nielsen, S. M., Stamp, L. K., Henriksen, Marius, Overgaard, A. F., Dreyer, L., Knop, Filip Krag, Singh, J. A., Doherty, M., Richette, P., Astrup, A., Ellegaard, K., Bartels, E. M., Boesen, Mikael Ploug, Gudbergsen, Henrik Rindel, Bliddal, Henning & Kristensen, L. E., 2024, In: Arthritis & rheumatology (Hoboken, N.J.). 766, 5, p. 806-812 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metabolic profile in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives
Coello, K., Vinberg, Maj, Knop, Filip Krag, Pedersen, Bente Klarlund, McIntyre, R. S., Kessing, Lars Vedel & Munkholm, K., 2019, In: International Journal of Bipolar Disorders. 7, 13 p., 8.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial prolactin suppression appears absent in antipsychotic-treated male patients
Coello, K., Broberg, B. V., Bak, N., Madsen, A., Mortensen, H. B., Søgaard, B., Szecsi, P. B., Knop, Filip Krag, Lublin, H. & Ebdrup, B. H., Oct 2015, In: Psychoneuroendocrinology. 60, p. 1-6 6 p.Research output: Contribution to journal › Letter › Research › peer-review
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The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes
Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Hansen, L. S., Hansen, N. L., Stensen, S., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: European Journal of Endocrinology. 184, 3, p. 387-398 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of glucagon-like peptide-1 receptor agonists on cardiovascular risk factors: A narrative review of head-to-head comparisons
Dalsgaard, N. B., Vilsbøll, Tina & Knop, Filip Krag, Mar 2018, In: Diabetes, Obesity and Metabolism. 20, 3, p. 508-519Research output: Contribution to journal › Review › Research › peer-review
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Cardiovascular safety and benefits of GLP-1 receptor agonists
Dalsgaard, N. B., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 351-363 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes
Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Helsted, M. M., Hansen, L. S., Hansen, N. L., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Bone. 170, 116687.Research output: Contribution to journal › Journal article › Research › peer-review
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Metformin treatment is associated with reduced risk of hypoglycaemia, major adverse cardiovascular events, and all-cause mortality in patients with post-pancreatitis diabetes mellitus: a nationwide cohort study
Davidsen, L., Jensen, M. H., Cook, M. E., Vestergaard, P., Knop, Filip Krag, Drewes, A. M. & Olesen, S. S., 2024, In: European Journal of Endocrinology. 190, 1, p. 44-53 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Promising translatable pharmacological interventions for body weight management in individuals with severe mental illness - a narrative review
De, R., Prasad, F., Stogios, N., Burin, L., Ebdrup, Bjørn, Knop, Filip Krag, Hahn, M. K. & Agarwal, S. M., 2023, In: Expert Opinion on Pharmacotherapy. 24, 16, p. 1823-1832 10 p.Research output: Contribution to journal › Review › Research › peer-review
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Effects of liraglutide on cardiovascular risk factors in patients with type 1 diabetes
Dejgaard, T. F., Johansen, N. B., Frandsen, C. S. S., Asmar, A., Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., May 2017, In: Diabetes, Obesity and Metabolism. 19, 5, p. 734–738Research output: Contribution to journal › Letter › Research › peer-review
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Efficacy and safety of liraglutide for overweight adult patients with type 1 diabetes and insufficient glycaemic control (Lira-1): a randomised, double-blind, placebo-controlled trial
Dejgaard, T. F., Frandsen, C. S., Hansen, T. S., Almdal, Thomas Peter, Urhammer, Søren Asger, Pedersen-Bjergaard, Ulrik, Jensen, T., Jensen, Andreas Kryger, Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., Mar 2016, In: The Lancet Diabetes & Endocrinology. 4, 3, p. 221–232 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy and safety of the glucagon-like peptide-1 receptor agonist liraglutide added to insulin therapy in poorly regulated patients with type 1 diabetes-a protocol for a randomised, double-blind, placebo-controlled study: The Lira-1 study
Dejgaard, T. F., Knop, Filip Krag, Tarnow, L., Frandsen, C. S., Hansen, T. S., Almdal, Thomas Peter, Holst, Jens Juul, Madsbad, Sten & Andersen, H. U., 2015, In: B M J Open. 5, 4, p. 1-8 8 p., e007791.Research output: Contribution to journal › Journal article › Research › peer-review
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Determinants of Fasting Hyperglucagonemia in Patients with Type 2 Diabetes and Nondiabetic Control Subjects
Demant, M., Bagger, J. I., Suppli, M. P., Lund, A., Gyldenløve, M., Hansen, K. B., Hare, Kristine Juul, Christensen, Mikkel Bring, Sonne, D. P., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2018, In: Metabolic Syndrome and Related Disorders. 16, 10, p. 530-536 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metabolic effects of one-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults
Demant, Mia Grønlund, Suppli, M. P., Foghsgaard, S., Gether, L., Grøndahl, M. F. G., Dalsgaard, N. B., Bergmann, S. S., Lanng, A. R., Gasbjerg, Lærke Smidt, Thomasen, M., Bagger, J. I., Strandberg, C., Kønig, M. J., Grønbæk, H., Becker, U., Holst, Jens Juul, Knop, J., Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 23-32Research output: Contribution to journal › Journal article › Research › peer-review
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'No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia': authors' response
Ebdrup, Bjørn, Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag & Glenthøj, Birte Yding, Nov 2017, In: Acta Psychiatrica Scandinavica. 136, 5, p. 526-527Research output: Contribution to journal › Comment/debate › Research
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Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients
Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight gain on antipsychotics – A perfect storm of complex pathophysiology and psychopharmacology
Ebdrup, Bjørn & Knop, Filip Krag, 2021, In: Acta Psychiatrica Scandinavica. 144, 6, p. 521-523 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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Incidence and Prognosis of Psoriasis and Psoriatic Arthritis in Patients Undergoing Bariatric Surgery
Egeberg, A., Sørensen, J. A., Gislason, Gunnar Hilmar, Knop, Filip Krag & Skov, Lone, 2017, In: J A M A Surgery. 152, 4, p. 344-349Research output: Contribution to journal › Journal article › Research › peer-review
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Pregnancy loss is associated with type 2 diabetes: a nationwide case-control study
Egerup, P., Mikkelsen, A. P., Kolte, A. M., Westergaard, D., Rasmussen, S., Knop, Filip Krag, Lidegaard, Øjvind & Nielsen, Henriette Svarre, 2020, In: Diabetologia. 63, 8, p. 1521-1529Research output: Contribution to journal › Journal article › Research › peer-review
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Why diversity among participants in clinical studies is not always preferable: the case for small, exploratory studies
Ellegaard, A. M. & Knop, Filip Krag, 2023, In: BMC Medicine. 21, 1, 3 p., 462.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Author Response to Letter to the Editor regarding “the Epidemiology of Bile Acid Diarrhea in Denmark” [Response to Letter]
Ellegaard, A. M., Kårhus, M. L., Knop, Filip Krag & Kårhus, L. L., 2024, In: Clinical Epidemiology. 16, p. 5-6 2 p.Research output: Contribution to journal › Letter › Research › peer-review
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MYC mRNA expression throughout the intestine is not associated with body mass index or type 2 diabetes
Ellegaard, A. & Knop, Filip Krag, 2022, In: Endocrinology, Diabetes and Metabolism. 5, 2, 4 p., 00327.Research output: Contribution to journal › Comment/debate › Research
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Intestinal expression profiles and hepatic expression of LEAP2, ghrelin and their common receptor, GHSR, in humans
Englund, A., Gilliam-Vigh, H., Suppli, M. P., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Peptides. 177, 7 p., 171227.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion
Eriksen, P. L., Vilstrup, H., Rigbolt, K., Suppli, M. P., Sørensen, M., Heebøll, S., Veidal, S. S., Knop, Filip Krag & Thomsen, K. L., 2019, In: Liver International. 39, 11, p. 2094-2101Research output: Contribution to journal › Journal article › Research › peer-review
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O12.4. EFFECTS OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST EXENATIDE ON BONE STATUS IN OBESE, NON-DIABETIC, ANTIPSYCHOTIC-TREATED SCHIZOPHRENIA SPECTRUM PATIENTS
Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jørgensen, Niklas Rye, Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Schizophrenia Bulletin. 45, Suppl. 2, p. S198-S199 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density
Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jorgensen, N. R., Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Frontiers in Psychiatry. 9, 7 p., 781.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele
Faerch, K., Pilgaard, K., Knop, Filip Krag, Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T. & Holst, Jens Juul, 2012, In: Diabetes, Obesity and Metabolism Online. 15, 1, p. 91-95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of statins and RAS inhibitors on the association between delayed antidiabetic treatment and the risk of cardiovascular event in patients with a first HbAlc between 48-57 mmol/mol
Falkentoft, A. C., Gerds, Thomas Alexander, Knop, Filip Krag, Fosbøl, E., Køber, Lars Valeur, Torp-Pedersen, Christian, Schou, M., Bruun, Niels Eske & Ruwald, A. C., 2022, In: European Heart Journal. 43, Supplement 1, p. 2419 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Risk of first-time major cardiovascular event among individuals with newly diagnosed type 2 diabetes: data from Danish registers
Falkentoft, A. C., Gerds, Thomas Alexander, Zareini, B., Knop, Filip Krag, Køber, Lars Valeur, Torp-Pedersen, Christian, Schou, Morten, Bruun, Niels Eske & Ruwald, A. C., 2023, In: Diabetologia. 66, p. 2017–2029 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improvement in psoriasis after treatment with the glucagon-like peptide-1 receptor agonist liraglutide
Faurschou, A., Knop, Filip Krag, Thyssen, Jacob Pontoppidan, Zachariae, C., Skov, Lone & Vilsbøll, Tina, 2011, In: Acta Diabetologica.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of effect of the glucagon-like peptide-1 receptor agonist liraglutide on psoriasis in glucose-tolerant patients – a randomized placebo-controlled trial
Faurschou, A., Gyldenløve, M., Rohde, U., Thyssen, Jacob Pontoppidan, Zachariae, Claus, Skov, L., Knop, Filip Krag & Vilsbøll, T., Mar 2015, In: Journal of the European Academy of Dermatology and Venereology. 29, 3, p. 555-559 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased expression of glucagon-like peptide-1 receptors in psoriasis plaques
Faurschou, A., Pedersen, Jens, Gyldenløve, M., Poulsen, Steen Seier, Holst, Jens Juul, Thyssen, Jacob Pontoppidan, Zachariae, Claus, Vilsbøll, Tina, Skov, Lone & Knop, Filip Krag, Feb 2013, In: Experimental Dermatology. 22, 2, p. 150-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric bypass surgery: Improving psoriasis through a GLP-1-dependent mechanism?
Faurschou, A., Zachariae, Claus, Skov, Lone, Vilsbøll, Tina & Knop, Filip Krag, 1 Oct 2011, In: Medical Hypotheses. 77, 6, p. 1098-1101Research output: Contribution to journal › Journal article › Research › peer-review
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Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control
Fernandez-Cachon, M. L., Pedersen, S. L., Rigbolt, K. T., Zhang, C., Fabricius, K., Hansen, H. H., Elster, L., Fink, L. N., Schäfer, M., Rhee, N. A., Langholz, E., Wandall, E., Friis, S. U., Vilmann, P., Kristiansen, V. B., Schmidt, C., Schreiter, K., Breitschopf, K., Hübschle, T., Jorsal, T. & 6 others, , Mar 2018, In: Peptides. 101, p. 32-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Editorial: Proglucagon-Derived Peptides
Flatt, P. R., Knop, Filip Krag & Tarasov, A. I., Nov 2021, In: Frontiers in Endocrinology. 12, 776871.Research output: Contribution to journal › Editorial › Research
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FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit
Flippo, K. H., Trammell, Sam, Gillum, M. P., Aklan, I., Perez, M. B., Yavuz, Y., Smith, N. K., Jensen-Cody, S. O., Zhou, B., Claflin, K. E., Beierschmitt, A., Fink-Jensen, Anders, Knop, Filip Krag, Palmour, R. M., Grueter, B. A., Atasoy, D. & Potthoff, M. J., 2022, In: Cell Metabolism. 34, 2, p. 317-328.e6Research output: Contribution to journal › Journal article › Research › peer-review
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Is double-blinding achievable in a placebo-controlled trial with the glucagon-like-peptide-1 receptor agonist liraglutide?
Foghsgaard, S., Vedtofte, L., Bahne, E., Andreasen, C., Christiansen, L. K., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetologia. 60, S1, p. S369-S369Research output: Contribution to journal › Conference abstract in journal › Research
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The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial
Foghsgaard, S., Vedtofte, L., Mathiesen, Elisabeth, Svare, J. A., Gluud, Lise Lotte, Holst, Jens Juul, Damm, Peter, Knop, Filip Krag & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference
Foghsgaard, S., Andreasen, C., Vedtofte, L., Andersen, E. S., Bahne, E., Strandberg, C., Buhl, T., Holst, Jens Juul, Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, Jan 2017, In: Diabetes Care. 40, 1, p. 109-116 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial
Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect
Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Palaeolithic diet decreases fasting plasma leptin concentrations more than a diabetes diet in patients with type 2 diabetes: A randomised cross-over trial
Fontes-Villalba, M., Lindeberg, S., Granfeldt, Y., Knop, Filip Krag, Memon, A. A., Carrera-Bastos, P., Picazo, Ó., Chanrai, M., Sunquist, J., Sundquist, K. & Jönsson, T., 2016, In: Cardiovascular Diabetology. 15, 1, 10 p., 80.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating Levels of the Soluble Receptor for AGE (sRAGE) during Escalating Oral Glucose Dosages and Corresponding Isoglycaemic i.v. Glucose Infusions in Individuals with and without Type 2 Diabetes
Fotheringham, A. K., Bagger, J. I., Borg, D. J., McCarthy, D. A., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Forbes, J. M., 2020, In: Nutrients. 12, 10, 12 p., 2928.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy and safety of co-administered once-weekly cagrilintide 2·4 mg with once-weekly semaglutide 2·4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial
Frias, J. P., Deenadayalan, S., Erichsen, L., Knop, Filip Krag, Lingvay, I., Macura, S., Mathieu, C., Pedersen, S. D. & Davies, M., 2023, In: The Lancet. 402, 10403, p. 720-730 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose metabolism in patients with psoriasis
Friis, N. U., Hoffmann, N., Gyldenlove, M., Skov, Lone, Vilsbøll, Tina, Knop, Filip Krag & Storgaard, H., 2019, In: British Journal of Dermatology. 180, 2, p. 264-271Research output: Contribution to journal › Review › Research › peer-review
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Prevalence and predictive features of metabolic dysfunction-associated steatotic liver disease in type 1 diabetes
Fuhri Snethlage, C. M., Meijnikman, A. S., Mak, A. L., Rampanelli, E., Voermans, B., Callender, C. A. K., De Groen, P., Roep, B. O., Van Raalte, D. H., Knop, Filip Krag, Holleboom, A. G., Nieuwdorp, M. & Hanssen, N. M. J., 2024, In: European Journal of Endocrinology. 190, 5, p. 391-400 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects
Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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GIP's effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3-30)NH2
Gasbjerg, Lærke Smidt, Hartmann, Bolette, Christensen, Mikkel Bring, Lanng, A. R., Vilsbøll, Tina, Jørgensen, Niklas Rye, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 130, 6 p., 115079 .Research output: Contribution to journal › Journal article › Research › peer-review
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Dose-dependent efficacy of the glucose-dependent insulinotropic polypeptide (GIP)receptor antagonistGIP(3-30)NH2 on GIP actions in humans
Gasbjerg, Lærke Smidt, Bari, E. J., Stensen, S., Hoe, B., Lanng, A. R., Mathiesen, D. S., Christensen, Mikkel Bring, Hartmann, Bolette, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, 1, p. 68-74Research output: Contribution to journal › Journal article › Research › peer-review
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GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study
Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423Research output: Contribution to journal › Journal article › Research › peer-review
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Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals
Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Jensen, M. H., Gabe, M. B. N., wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2019, In: Diabetes. 68, 3, p. 906-917Research output: Contribution to journal › Journal article › Research › peer-review
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GIP and GLP-1 Receptor Antagonism During a Meal in Healthy Individuals
Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e725-e738 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists
Gasbjerg, Lærke Smidt, Bergmann, N. C., Stensen, S., Christensen, Mikkel Bring, Rosenkilde, Mette, Holst, Jens Juul, Nauck, M. & Knop, Filip Krag, 2020, In: Peptides. 125, 10 p., 170183.Research output: Contribution to journal › Review › Research › peer-review
- Published
The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide
Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092Research output: Contribution to journal › Review › Research › peer-review
- Published
Exendin(9-39)NH2: Recommendations for clinical use based on a systematic literature review
Gasbjerg, Lærke Smidt, Bari, E. J., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, 11, p. 2419-2436Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents
Gasbjerg, Lærke Smidt, Gabe, M. B. N., Hartmann, Bolette, Christensen, Mikkel Bring, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Feb 2018, In: Peptides. 100, p. 173-181Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colesevelam has no acute effect on postprandial GLP-1 levels but abolishes gallbladder refilling
Gether, I. M., Bahne, E., Nerild, H. H., Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2024, In: European Journal of Endocrinology. 190, 4, p. 314-326 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New Avenues in the Regulation of Gallbladder Motility: Implications for the Use of Glucagon-Like Peptide-Derived Drugs
Gether, I. M., Nexøe-Larsen, C. & Knop, Filip Krag, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2463-2472Research output: Contribution to journal › Review › Research › peer-review
- Published
Gastric Aspiration Improves Postprandial Glucose Tolerance Without Causing a Compensatory Increase in Appetite and Food Intake
Gether, I. M., Jensen, M. M., Nexøe-Larsen, C. C., Jorsal, T., Gasbjerg, Lærke Smidt, Naver, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Obesity Surgery. 32, p. 1385–1390Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal insulin sensitivity, glucose tolerance, gut incretin and pancreatic hormone responses in adults with atopic dermatitis
Gether, L., Thyssen, Jacob Pontoppidan, Gyldenlove, M., Hartmann, Bolette, Holst, Jens Juul, Foghsgaard, S., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes, Obesity and Metabolism. 22, 11, p. 2161-2169 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of topical corticosteroid vs. tacrolimus on insulin sensitivity and bone homeostasis in adults with atopic dermatitis - a randomized controlled study
Gether, L., Storgaard, H., Kezic, S., Jakasa, I., Hartmann, Bolette, Skov-Jeppesen, Kirsa, Holst, Jens Juul, Pedersen, A. J., Forman, Julie Lyng, van Hall, Gerrit, Sørensen, O. E., Skov, Lone, Røpke, Mads Almose, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, 2023, In: Allergy. 78, 7, p. 1964-1979 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of Secretin and its Receptor Along the Intestinal Tract in Type 2 Diabetes Patients and Healthy Controls
Gilliam-Vigh, H., Jorsal, T., Nielsen, S. W., Forman, Julie Lyng, Pedersen, Jens, Poulsen, Steen Seier, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 12, p. e1597–e1602 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of Neurotensin and Its Receptors Along the Intestinal Tract in Type 2 Diabetes Patients and Healthy Controls
Gilliam-Vigh, H., Jorsal, T., Nielsen, S. W., Forman, Julie Lyng, Pedersen, Jens, Poulsen, Steen Seier, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Journal of Clinical Endocrinology & Metabolism. p. 2211–2216 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of Cholecystokinin and its Receptors in the Intestinal Tract of Type 2 Diabetes Patients and Healthy Controls
Gilliam-Vigh, H., Jorsal, T., Rehfeld, Jens Frederik, Pedersen, Jens, Poulsen, Steen Seier, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 8, p. 2164-2170 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of lixisenatide on elevated liver transaminases: systematic review with individual patient data meta-analysis of randomised controlled trials on patients with type 2 diabetes
Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, T., 2014, In: B M J Open. 4, 12, p. 1-10 10 p., e005325.Research output: Contribution to journal › Review › Research › peer-review
- Published
N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis
Grevengoed, Trisha Jean, Trammell, Sam, McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexøe-Larsen, C. C., Knop, Filip Krag, Schwartz, Thue W., Kibbey, R. G., Cravatt, B. F. & Gillum, M. P., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24770-24778Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes in children: what are the specific considerations?
Grondahl, M. F. G., Johannesen, Jesper, Kristensen, K. & Knop, Filip Krag, 2021, In: Expert Opinion on Pharmacotherapy. 22, 16, p. 2127-2141 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current Therapies That Modify Glucagon Secretion: What Is the Therapeutic Effect of Such Modifications?
Grøndahl, M. F., Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Current Diabetes Reports. 17, 12, 10 p., 128.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers
Grøndahl, M. F., Bagger, J. I., Lund, A., Faurschou, A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jun 2018, In: Diabetes Care. 41, 6, p. 1260-1267Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon Clearance is Preserved in Type 2 Diabetes
Grøndahl, M. F. G., Lund, A., Bagger, J. I., Petersen, Tonny Studsgaard, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 1, db210024.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity
Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide after diet-induced weight loss for pain and weight control in knee osteoarthritis: A randomized controlled trial
Gudbergsen, Henrik Rindel, Overgaard, A., Henriksen, Marius, Wæhrens, E. E., Bliddal, Henning, Christensen, R., Nielsen, S. M., Boesen, Mikael Ploug, Knop, Filip Krag, Astrup, A., Rasmussen, M. U., Bartholdy, C., Daugaard, C. L., Ellegaard, K., Heitmann, Berit, Bartels, E. M., Danneskiold-Samsøe, B. & Kristensen, L. E., 2021, In: American Journal of Clinical Nutrition. 113, 2, p. 314–323 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EFFECT OF LIRAGLUTIDE ON BODY WEIGHT AND PAIN IN THE TREATMENT OF OVERWEIGHT AND KNEE OSTEOARTHRITIS: A RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY
Gudbergsen, H., Overgaard, A., Henriksen, Marius, Waehrens, E. E., Bliddal, Henning, Christensen, R., Nielsen, S. M., Boesen, Mikael Ploug, Knop, Filip Krag, Astrup, A., Rasmussen, M. U., Bartholdy, C. R., Daugaard, C., Bartels, E. M., Ellegaard, K., Heitmann, Berit & Kristensen, L. E., 2019, In: Annals of the Rheumatic Diseases. 78, p. 71-72 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Effect of liraglutide on body weight and pain in patients with overweight and knee osteoarthritis: protocol for a randomised, double-blind, placebocontrolled, parallel-group, singlecentre trial
Gudbergsen, Henrik Rindel, Henriksen, M., Wæhrens, E. E., Overgaard, A., Bliddal, H., Christensen, R., Boesen, Mikael Ploug, Knop, Filip Krag, Astrup, A., Rasmussen, M. U., Bartholdy, C., Daugaard, C., Bartels, E. M., Ellegaard, K., Heitmann, Berit & Kristensen, L. E., 2019, In: B M J Open. 9, 5, 12 p., e024065.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism-Based Modeling of Gastric Emptying Rate and Gallbladder Emptying in Response to Caloric Intake
Guiastrennec, B., Sonne, D. P., Hansen, M., Bagger, J. I., Lund, A., Rehfeld, Jens Frederik, Alskär, O., Karlsson, M. O., Vilsbøll, Tina, Knop, Filip Krag & Bergstrand, M., Dec 2016, In: C P T: Pharmacometrics & Systems Pharmacology. 5, 12, p. 692-700 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Model-Based Prediction of Plasma Concentration and Enterohepatic Circulation of Total Bile Acids in Humans
Guiastrennec, B., Sonne, David Peick, Bergstrand, M., Vilsbøll, Tina, Knop, Filip Krag & Karlsson, M. O., 2018, In: C P T: Pharmacometrics & Systems Pharmacology. 7, 9, p. 603-612Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired incretin effect is an early sign of glucose dysmetabolism in nondiabetic patients with psoriasis
Gyldenløve, M., Vilsbøll, Tina, Zachariae, Claus, Holst, Jens Juul, Knop, Filip Krag & Skov, Lone, 11 Nov 2015, In: Journal of Internal Medicine. 278, 6, p. 660-70 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disturbed postprandial glucose metabolism and gut hormone responses in non-diabetic patients with psoriasis
Gyldenløve, M., Vilsbøll, Tina, Holst, Jens Juul, Zachariae, Claus, Skov, L. & Knop, Filip Krag, Nov 2016, In: British Journal of Dermatology. 175, 5, p. 1085–1088Research output: Contribution to journal › Letter › Research › peer-review
- Published
Patients with psoriasis are insulin resistant
Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Effects of oral roflumilast therapy on body weight and cardiometabolic parameters in patients with psoriasis – results from a randomized controlled trial (PSORRO)
Gyldenløve, Mette, Sørensen, J. A., Fage, S., Meteran, H., Skov, Lone, Zachariae, Claus, Knop, Filip Krag, Nielsen, M. L. & Egeberg, Alexander, 2024, (Accepted/In press) In: Journal of the American Academy of Dermatology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Psoriasis er associeret med type 2-diabetes
Gyldenl�ve, M., Knop, Filip Krag, Vilsb�ll, T., Zachariae, Claus & Skov, Lone, 4 Mar 2013, In: Ugeskrift for Laeger. 175, 10, p. 652-4 3 p., 652.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition
Haedersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, p. S312-S312.Research output: Contribution to conference › Poster › Research
- Published
Exercise-related hypoglycaemia induces QTc-interval prolongation in individuals with type 1 diabetes
Hagelqvist, P. G., Andersen, A., Maytham, K. B., Andreasen, C. R., Engberg, S., Lindhardt, T. B., Faber, Jens, Holst, Jens Juul, Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 5, p. 1186-1195 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycaemia and cardiac arrhythmias in people with type 1 diabetes: A prospective observational study
Hagelqvist, P. G., Andersen, A., Maytham, K., Andreasen, C. R., Engberg, S., Lindhardt, T. B., Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 8, p. 2300-2309Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Hemostatic Effects of Exercise-Related Hypoglycemia in Male Persons With Type 1 Diabetes
Hagelqvist, P. G., Andersen, A., Maytham, K., Andreasen, C. R., Engberg, S., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Johansson, Pär Ingemar , Lykkesfeldt, Jens, Knop, Filip Krag & Vilsbøll, Tina, 2024, (E-pub ahead of print) In: The Journal of clinical endocrinology and metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exogenous LEAP2 improves postprandial glucose tolerance and reduces ad libitum food intake in men
Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Heimburger, S. M. N., Dela, Flemming, Vilsbøll, Tina, Holst, Birgitte & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 23-23 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity
Hagemann, C. A., Legart, C., Møllerhøj, M. B., Madsen, M. R., Hansen, H. H., Kønig, M. J., Helgstrand, Frederik, Hjørne, F. P., Toxværd, A., Langhoff, J. L., Kielgast, U. L., Gluud, Lise Lotte, Ægidius, H., Rigbolt, K. T. G., Vilsbøll, Tina, Jelsing, J. & Knop, Filip Krag, 2022, In: PLoS ONE. 17, 10, 19 p., e0275901.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men
Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol for assessing the effects of exogenous hormone administration on human postprandial glucose metabolism, appetite sensations, and food intake
Hagemann, C. A., Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring & Knop, Filip Krag, 2023, In: STAR Protocols. 4, 1, 10 p., 102070.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment
Hagemann, C. A., Zhang, C., Hansen, H. H., Jorsal, T., Rigbolt, K. T. G., Madsen, M. R., Bergmann, N. C., Heimbürger, S. M. N., Falkenhahn, M., Theis, S., Breitschopf, K., Holm, Stephanie Kjærulff, Hedegaard, M. A., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Birgitte, Vrang, N., Jelsing, J. & Knop, Filip Krag, 2021, In: The Journal of clinical endocrinology and metabolism. 106, 2, p. e966-e981Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes
Halden, T. A. S., Egeland, E. J., Åsberg, A., Hartmann, A., Midtvedt, K., Khiabani, H. Z., Holst, Jens Juul, Knop, Filip Krag, Hornum, Mads, Feldt-Rasmussen, Bo & Jenssen, T., 23 Feb 2016, In: Diabetes Care. 39, p. 617-24Research output: Contribution to journal › Journal article › Research › peer-review
ID: 40100368
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
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