Filip Krag Knop

Filip Krag Knop

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


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  1. Published

    'No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia': authors' response

    Ebdrup, Bjørn, Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag & Glenthøj, Birte Yding, Nov 2017, In: Acta Psychiatrica Scandinavica. 136, 5, p. 526-527

    Research output: Contribution to journal › Comment/debate › Research

  2. Published

    100 years of glucagon and 100 more

    Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cherrington, A. D., Finan, B., Gluud, Lise Lotte, Dean, E. D., Campbell, J. E., Bloom, S. R., Tan, T. M., Knop, Filip Krag & Müller, T. D., 2023, In: Diabetologia. 66, p. 1378–1394

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

    Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    MYC mRNA expression throughout the intestine is not associated with body mass index or type 2 diabetes

    Ellegaard, A. & Knop, Filip Krag, 2022, In: Endocrinology, Diabetes and Metabolism. 5, 2, 4 p., 00327.

    Research output: Contribution to journal › Comment/debate › Research

  5. Published

    N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis

    Grevengoed, Trisha Jean, Trammell, Sam, McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexøe-Larsen, C. C., Knop, Filip Krag, Schwartz, Thue W., Kibbey, R. G., Cravatt, B. F. & Gillum, M. P., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24770-24778

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A 25-year-old woman with type 2 diabetes and liver disease

    Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A Pharmacological and Clinical Overview of Oral Semaglutide for the Treatment of Type 2 Diabetes

    Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Drugs. 81, p. 1003-1030 28 p.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    A comprehensive compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects

    Vahidi, O., Kwok, K. E., Gopaluni, R. B. & Knop, Filip Krag, 2016, In: Medical & Biological Engineering & Computing. 54, 9, p. 1383-1398 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A gut feeling about glucagon: Eje Prize 2018

    Knop, Filip Krag, 2018, In: European Journal of Endocrinology. 178, 6, p. R267-R280 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity

    Hagemann, C. A., Legart, C., Møllerhøj, M. B., Madsen, M. R., Hansen, H. H., Kønig, M. J., Helgstrand, Frederik, Hjørne, F. P., Toxværd, A., Langhoff, J. L., Kielgast, U. L., Gluud, Lise Lotte, Ægidius, H., Rigbolt, K. T. G., Vilsbøll, Tina, Jelsing, J. & Knop, Filip Krag, 2022, In: PLoS ONE. 17, 10, 19 p., e0275901.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A role for exogenous GLP-1 in the management of postprandial hypoglycaemia after Roux-en-Y gastric bypass?

    Øhrstrøm, C. C. & Knop, Filip Krag, 2019, In: European Journal of Endocrinology. 181, 3, p. C5-C8

    Research output: Contribution to journal › Comment/debate › Research

  13. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

    Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Helsted, M. M., Hansen, L. S., Hansen, N. L., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Bone. 170, 116687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Accuracy of continuous glucose monitoring during exercise-related hypoglycemia in individuals with type 1 diabetes

    Maytham, K., Hagelqvist, P. G., Engberg, S., Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag, Vilsbøll, Tina & Andersen, A., 2024, In: Frontiers in Endocrinology. 15, 9 p., 1352829.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls

    Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, Mikkel Bring, Pedersen-Bjergaard, Ulrik, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1123-1131

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Acute concomitant GIP receptor antagonism during GLP-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity

    Stensen, S., Krogh, L. L., wbf943, wbf943, Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 9, p. 1882-1887

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls

    Andersen, A., Bagger, J. I., Baldassarre, M. P., Christensen, Mikkel Bring, Abelin, K. U., Faber, Jens, Pedersen-Bjerregaard, U., Holst, Jens Juul, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: European Journal of Endocrinology. 185, 2, p. 343-353 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Adaptive changes in pancreas post Roux-en-Y gastric bypass induced weight loss

    Lautenbach, A., Wernecke, M., Riedel, N., Veigel, J., Yamamura, J., Keller, S., Jung, R., Busch, P., Mann, O., Knop, Filip Krag, Holst, Jens Juul, Meier, J. J. & Aberle, J., Oct 2018, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 7, p. 1-8 e3025.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Adult atopic dermatitis and the risk of type 2 diabetes

    Andersen, Y. M. F., Egeberg, A., Gislason, Gunnar Hilmar, Skov, Lone, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, Mar 2017, In: The Journal of allergy and clinical immunology. 139, 3, p. 1057-1059 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  21. Published

    Adverse drug reactions associated with the use of liraglutide in patients with type 2 diabetes-focus on pancreatitis and pancreas cancer

    Chalmer, T., Almdal, Thomas Peter, Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Expert Opinion on Drug Safety. 14, 1, p. 171-180

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Albiglutide for treating type 2 diabetes: an evaluation of pharmacokinetics/pharmacodynamics and clinical efficacy

    Brønden, A., Naver, S. V., Knop, Filip Krag & Christensen, M., 2015, In: Expert Opinion on Drug Metabolism & Toxicology. 11, 9, p. 1493-1503 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Alpha- and beta-cell abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes

    Calanna, S., Scicali, R., Di Pino, A., Knop, Filip Krag, Piro, S., Rabuazzo, A. M. & Purrello, F., 2014, In: Acta Diabetologica. 51, 4, p. 567-575

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Alterations in blood microbiota after colonic cancer surgery

    Søby, J. H., Watt, S. K., Vogelsang, R. P., Servant, F., Lelouvier, B., Raskov, H., Knop, Filip Krag & Gögenur, Ismail, 2020, In: BJS open. 4, 6, p. 1227-1237

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Amylin and Calcitonin: Potential Therapeutic Strategies to Reduce Body Weight and Liver Fat

    Mathiesen, D. S., Lund, A., Vilsbøll, Tina, Knop, Filip Krag & Bagger, J. I., 2021, In: Frontiers in Endocrinology. 11, 617400.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    An Extended Minimal Model of OGTT: estimation of α- and β-cell dysfunction, insulin resistance, and the incretin effect

    Subramanian, V., Bagger, J. I., Harihar, V., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 2, p. E182-E205

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight

    Theilade, Karen Simone, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, S1, p. 17-35 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Antidiabetes Agents and Incident Depression: A Nationwide Population-Based Study

    Kessing, Lars Vedel, Rytgaard, Helene Charlotte Wiese, Ekstrøm, Claus Thorn, Knop, Filip Krag, Berk, M. & Gerds, Thomas Alexander, 2020, In: Diabetes Care. 43, 12, p. 3050-3060

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

    Kim, A., Knudsen, J. G., Madara, J. C., Benrick, A., Hill, T. G., Kadir, L. A., Kellard, J. A., Mellander, L., Miranda, C., Lin, H., James, T., Suba, K., Spigelman, A. F., Wu, Y., Macdonald, P. E., Asterholm, I. W., Magnussen, T., Christensen, M., Vilsbøll, T., Salem, V. & 4 others, Knop, Filip Krag, Rorsman, P., Lowell, B. B. & Briant, L. J. B., 2021, In: eLife. 10, 29 p., e72919.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Association between topical corticosteroid use and type 2 diabetes in two European population-based adult cohorts

    Andersen, Y. M. F., Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, Filip Krag, Gislason, Gunnar Hilmar, Skov, Lone & Thyssen, Jacob Pontoppidan, 2019, In: Diabetes Care. 42, 6, p. 1095-1103

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Associations of hypoglycaemia and glycaemic variability with cardiac arrhythmias using a long-term monitoring approach in insulin-treated patients with type 2 diabetes

    Andersen, A., Bagger, J. I., Sorensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-135 257.

    Research output: Contribution to journal › Conference abstract in journal › Research

  32. Published

    Associations of hypoglycemia, glycemic variability and risk of cardiac arrhythmias in insulin-treated patients with type 2 diabetes: a prospective, observational study

    Andersen, A., Bagger, J. I., Sørensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Cardiovascular Diabetology. 20, 1, 10 p., 241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Author Response to Letter to the Editor regarding “the Epidemiology of Bile Acid Diarrhea in Denmark” [Response to Letter]

    Ellegaard, A. M., Kårhus, M. L., Knop, Filip Krag & Kårhus, L. L., 2024, In: Clinical Epidemiology. 16, p. 5-6 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  34. Published

    Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial

    Sivapalan, P. & ProPAC-COVID writing group on behalf of the ProPAC-COVID Study Group, P. W. G. O. B. O. T. P. S. G., 2022, In: European Respiratory Journal. 59, 1, 2100752.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Bariatric surgery in patients with non-alcoholic fatty liver disease from pathophysiology to clinical effects

    Laursen, T. L., Hagemann, C. A., Wei, C., Kazankov, K., Thomsen, K. L., Knop, Filip Krag & Gronbaek, H., 2019, In: World Journal of Hepatology. 11, 2, p. 138-149

    Research output: Contribution to journal › Review › Research › peer-review

  36. Published

    Behandling med duodenal-jejunal bypass-sleeve ved svær overvægt

    Rohde, U., Gylvin, S., Vilmann, Peter, Friis, S. U., Langholz, Ebbe, Vilsbøll, T. & Knop, Filip Krag, 29 Sep 2014, In: Ugeskrift for Laeger. 176, 37, p. 1874-1877 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

    Storgaard, H., Gluud, Lise Lotte, Bennett, C., Grøndahl, M. F., Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, Tina, 2016, In: PLOS ONE. 11, 11, 23 p., e0166125.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2

    Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Betydningen af inkretinhormonerne glucose-dependent insulinotropic peptide og glucagon-like peptide-1 for patogenesen ved type 2-diabetes mellitus

    Vilsbøll, Tina & Knop, Filip Krag, 28 May 2007, In: Ugeskrift for Laeger. 169, 22, p. 2101-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Bifidobacterium breve Bif195 ameliorates aspirin-induced gastric mucosal damage: A randomised, double blind, placebo-controlled crossover trial

    Løn, N., Engel, S., Damholt, A., Mortensen, B., Haaber, A. B., Wellejus, A. & Knop, Filip Krag, 2024, In: Alimentary Pharmacology and Therapeutics. 59, 3, p. 341-349 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Bile acid sequestrants: Glucose-lowering mechanisms and efficacy in type 2 diabetes

    Hansen, M., Sonne, David Peick & Knop, Filip Krag, May 2014, In: Current Diabetes Reports. 14, 5, 482.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials

    Hansen, M., Sonne, David Peick, Mikkelsen, K. H., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2017, In: Journal of Diabetes and its Complications. 31, 5, p. 918-927 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial

    Hvistendahl, M. K., Naimi, R. M., Hansen, S. H., Rehfeld, Jens Frederik, Kissow, Hannelouise, Pedersen, Jens, Dragsted, Lars Ove, Sonne, D. P., Knop, Filip Krag & Jeppesen, Palle Bekker, 2022, In: Journal of Parenteral and Enteral Nutrition. 46, 4, p. 923-935 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?

    Knop, Filip Krag, 1 Jul 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 1, p. E10-3

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Biomarkører for kardiovaskulær sygdom ved type 2-diabetes

    Krogh, S. K., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Ugeskrift for Laeger. 181, 6 p., V10180711.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density

    Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jorgensen, N. R., Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Frontiers in Psychiatry. 9, 7 p., 781.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Bone Turnover Markers in Patients With Nonalcoholic Fatty Liver Disease and/or Type 2 Diabetes During Oral Glucose and Isoglycemic Intravenous Glucose

    Maagensen, H., Junker, A. E., Jorgensen, N. R., Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 2042-2049 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Call for prospective studies of continuous glucose monitoring to define the glycaemic response to bariatric surgery

    Bally, L., Khoo, B., Knop, Filip Krag, Madsbad, Sten, Patti, M. & Tan, T., 2023, In: The Lancet Diabetes and Endocrinology. 11, 10, p. 712-714 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  49. Published

    Cardiovascular biomarkers in clinical studies of type 2 diabetes

    Baldassarre, M. P. A., Andersen, A., Consoli, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1350-1360

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    Cardiovascular effects of high-dose glucagon: a randomised clinical trial

    Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

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