Filip Krag Knop

Filip Krag Knop

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


Publication year:
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501 - 546 out of 546Page size: 100
  1. 2011
  2. Published

    Therapy for obesity based on gastrointestinal hormones

    Bagger, J. I., Christensen, M., Knop, Filip Krag & Vilsbøll, Tina, 2011, In: Review of Diabetic Studies. 8, 3, p. 339-47 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2010
  4. Published

    Dulaglutide, a long-acting GLP-1 analog fused with an Fc antibody fragment for the potential treatment of type 2 diabetes

    Solem, Espen Victor Jimenez, Rasmussen, M. H., Christensen, M. & Knop, Filip Krag, 1 Dec 2010, In: Current Opinion in Molecular Therapeutics. 12, 6, p. 790-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis

    Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T. M., 24 Sep 2010, In: Regulatory Peptides. 164, 2-3, p. 144-50 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency

    Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes

    Christensen, M., Knop, Filip Krag, Vilsbøll, Tina, Aaboe, K., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 9 Aug 2010, In: Regulatory Peptides. 163, 1-3, p. 96-101 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?

    Knop, Filip Krag, 1 Jul 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 1, p. E10-3

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Incretin hormones and beta cell function in chronic pancreatitis

    Knop, Filip Krag, 1 Jul 2010, In: Danish Medical Bulletin (Online). 57, 7, p. B4163

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects

    Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 1 Jul 2010, In: The Journal of clinical endocrinology and metabolism. 95, 7, p. 3309-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action

    Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Comment on: Villareal et al. (2009) TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes;59:479-485

    Knop, Filip Krag, 1 Jun 2010, In: Diabetes. 59, 6, p. e4; author reply e5-6

    Research output: Contribution to journal › Letter › Research › peer-review

  13. Published

    Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

    Asmar, M., Bache, M., Knop, Filip Krag, Madsbad, Sten & Holst, Jens Juul, 1 May 2010, In: The Journal of clinical endocrinology and metabolism. 95, 5, p. 2367-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes

    Hare, K. J., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 1 Apr 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 4, p. E832-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Once-weekly GLP-1 agonists: How do they differ from exenatide and liraglutide?

    Christensen, M. & Knop, Filip Krag, 1 Apr 2010, In: Current Diabetes Reports. 10, 2, p. 124-32 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S. & Krarup, T. M., 1 Apr 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-33 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Incretin mimetics: a novel therapeutic option for patients with type 2 diabetes - a review

    Hansen, K. B., Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2010, In: Diabetes, Metabolic Syndrome and Obesity. 3, p. 155-63 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Incretin-based therapy and type 2 diabetes

    Hare, K. J. & Knop, Filip Krag, 1 Jan 2010, In: Vitamins and Hormones. 84, p. 389-413 25 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Increased Postprandial Response of Glucagon-Like Peptide-2 in Patients with Chronic Pancreatitis and Pancreatic Exocrine Insufficiency

    Hornum, Mads, Pedersen, J. F., Larsen, S., Olsen, O., Holst, Jens Juul & Knop, Filip Krag, 2010, In: Pancreatology. 10, 2-3, p. 201-207 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2009
  22. Published

    Glucagon-like peptide-1 and diabetes treatment

    Vilsbøll, Tina, Hare, K., Bagger, J. O. & Knop, Filip Krag, 2009, In: International Diabetes Monitor. 21, p. 1-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Incretin hormones and diabetes mellitus

    Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F. & Holst, Jens Juul, 2009, Therapeutic Strategies in Diabetes. Stehouwer, C. D. A. & Schaper, N. (eds.). Oxford: Clinical Publishing, p. 99-114

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  24. Published

    Incretin-based therapy of type 2 diabetes mellitus

    Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2009, In: Current Protein and Peptide Science. 10, 1, p. 46-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Holst, Jens Juul & Vilsboll, T., 2009, In: IDrugs. The Investigational Drugs Journal. 12, 8, p. 503-13 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

    Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Resolution of type 2 diabetes following gastric bypass surgery: involvement of gut-derived glucagon and glucagonotropic signalling?

    Knop, Filip Krag, 2009, In: Diabetologia. 52, 11, p. 2270-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The spectrum of antidiabetic actions of GLP-1 in patients with diabetes

    Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 453-62 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists

    Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, 2009, In: International Journal of Clinical Practice. 63, 8, p. 1154-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2008
  32. Published

    Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

    Højberg, P. V., Vilsbøll, Tina, Zander, P. M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, J. M. & Madsbad, Sten, 1 Nov 2008, In: Diabetic Medicine. 25, 11, p. 1268-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

    Højberg, P. V., Vilsbøll, T., Zander, M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, Nov 2008, In: Diabetic Medicine Online. 25, 11, p. 1268-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: challenges and feasibility

    Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, T., Jul 2008, In: I Drugs: the Investigational Drugs Journal. 11, 7, p. 497-501 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

    Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Long-acting GLP-1 analogs for the treatment of type 2 diabetes mellitus

    Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2008, In: BioDrugs. 22, 4, p. 251-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Højberg, P. V., Vilsbøll, Tina, Rabøl, R., Knop, Filip Krag, Bache, M., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2008, In: Diabetologia. 52, 2, p. 199-207 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Positioning Glucagon-like-peptide-1-based Treatment within an Optimal Manegement Regimen for Type 2 Diabetes

    Hansen, K. B., Vilsboll, T. & Knop, Filip Krag, 2008, In: European Journal of Endocrinology. Supplement. 4, p. 44-47 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2007
  41. Published

    Betydningen af inkretinhormonerne glucose-dependent insulinotropic peptide og glucagon-like peptide-1 for patogenesen ved type 2-diabetes mellitus

    Vilsbøll, Tina & Knop, Filip Krag, 28 May 2007, In: Ugeskrift for Laeger. 169, 22, p. 2101-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Glucagon-like peptide 1-baseret behandling af type 2-diabetes mellitus

    Knop, Filip Krag & Vilsbøll, Tina, 28 May 2007, In: Ugeskrift for Laeger. 169, 22, p. 2095-9 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus

    Knop, F. K., Vilsbøll, Tina, Madsbad, Sten, Holst, Jens Juul, Krarup, T., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Holst, J. M. & Krarup, T., 1 Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus

    Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Holst, Jens Juul & Krarup, T., Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. 2006
  46. Published

    Vaerdien af billeddiagnostiske undersøgelser ordineret i almen praksis

    Knop, Filip Krag & Stauning, J. A., 20 Feb 2006, In: Ugeskrift for Laeger. 168, 8, p. 794-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2005
  48. Published

    The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

    Schisler, J. C., Jensen, P. B., Harper, D. A. T., Becker, T., Knop, Filip Krag, Takekawa, S., German, M., Weir, G. C., Lu, D., Mirmira, R. G. & Newgard, C. B., 17 May 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 20, p. 7297-302 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2004
  50. Published

    Delayed ischemic cecal perforation despite optimal decompression after placement of a self-expanding metal stent: report of a case

    Knop, Filip Krag, Pilsgaard, B., Meisner, S. & Wille-Jørgensen, P., 1 Nov 2004, In: Diseases of the Colon and Rectum. 47, 11, p. 1970-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Self-expanding metal stents for colonic obstruction: experiences from 104 procedures in a single center

    Meisner, S., Hensler, M., Knop, Filip Krag, West, F. & Wille-Jørgensen, P., 1 Apr 2004, In: Diseases of the Colon and Rectum. 47, 4, p. 444-50 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 2003
  53. Published

    The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype

    Vilsbøll, Tina, Knop, Filip Krag, Krarup, T., Johansen, A., Madsbad, Sten, Larsen, S., Hansen, T., Pedersen, O., Holst, J. M. & Johansen, A., 1 Oct 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 10, p. 4897-903 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Small-bowel hemangiosarcoma and capsule endoscopy

    Knop, Filip Krag, Hansen, M. B. & Meisner, S., 1 Jul 2003, In: Endoscopy. 35, 7, p. 637

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    No hypoglycemia after subcutaneous administration of glucagon-like peptide-1 in lean type 2 diabetic patients and in patients with diabetes secondary to chronic pancreatitis.

    Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, J. J. & Krarup, T., 2003, In: Diabetes Care. 26, 9, p. 2581-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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