Gitte Moos Knudsen

Gitte Moos Knudsen

Clinical Professor

Member of:

  • Neurology


  1. 2010
  2. Published

    Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels

    Licht, C. L., Knudsen, Gitte Moos & Sharp, T., 31 May 2010, In: Neuroscience Letters. 476, 2, p. 58-61 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: a reproducibility study

    Ziebell, M., Pinborg, Lars Hageman, Thomsen, G., de Nijs, R., Svarer, C., Wagner, A. & Knudsen, Gitte Moos, 1 Jun 2010, In: Journal of Nuclear Medicine Technology. 38, 2, p. 61-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness

    Aznar, S., Klein, A. B., Santini, M. A., Knudsen, Gitte Moos, Henn, F., Gass, P. & Vollmayr, B., 1 Jul 2010, In: Synapse. 64, 7, p. 561-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Changes in 5-HT2A-mediated behavior and 5-HT2A- and 5-HT1A receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice

    Klein, A. B., Santini, M. A., Aznar, S., Knudsen, Gitte Moos & Rios, M., 1 Sep 2010, In: Laser Neuroscience. 169, 3, p. 1007-16 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding

    Frokjaer, V. G., Erritzoe, D., Juul, Anders, Nielsen, F. A., Holst, K., Svarer, C., Madsen, J., Paulson, Olaf B., Knudsen, Gitte Moos, Frøkjær, V., Erritzøe, D., Juul, Anders, Nielsen, F. Å., Holst, K., Svarer, C., Madsen, J., Paulson, O. B. & Knudsen, G. M., 1 Oct 2010, In: Psychoneuroendocrinology. 35, 9, p. 1311-20 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Measuring endogenous 5-HT release by emission tomography: promises and pitfalls

    Paterson, L. M., Tyacke, R. J., Nutt, D. J. & Knudsen, Gitte Moos, 1 Oct 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 10, p. 1682-706 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Structural combination of established 5-HT(2A) receptor ligands: new aspects of the binding mode

    Kramer, V., Herth, Matthias Manfred, Santini, M. A., Palner, M., Knudsen, Gitte Moos & Rösch, F., 1 Oct 2010, In: Chemical Biology & Drug Design (Online). 76, 4, p. 361-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Systemic catechol-O-methyl transferase inhibition enables the D1 agonist radiotracer R-[11C]SKF 82957

    Palner, M., McCormick, P., Parkes, J., Knudsen, Gitte Moos & Wilson, A. A., 1 Oct 2010, In: Nuclear Medicine and Biology. 37, 7, p. 837-43 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels

    Klein, A. B., Trajkovska, V., Erritzoe, D., Haugbol, S., Madsen, J., Baaré, W., Aznar, S. & Knudsen, Gitte Moos, 1 Nov 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 11, p. e1-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Novel radioiodinated {gamma}-hydroxybutyric acid analogues for radiolabeling and Photolinking of high-affinity {gamma}-hydroxybutyric acid binding sites

    Wellendorph, P., Høg, S., Sabbatini, P., Pedersen, M. H. F., Martiny, L., Knudsen, Gitte Moos, Frølund, B. F., Clausen, R. P. & Bräuner-Osborne, H., 1 Nov 2010, In: Journal of Pharmacology and Experimental Therapeutics. 335, 2, p. 458-64 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET

    Ettrup, A., Palner, M., Gillings, N., Santini, M. A., Hansen, M., Kornum, B. R., Rasmussen, L. K., Någren, K. Å., Madsen, J., Begtrup, M. & Knudsen, Gitte Moos, 1 Nov 2010, In: Journal of Nuclear Medicine. 51, 11, p. 1763-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET

    Ettrup, A., Palner, M., Gillings, N., Santini, M. A., Hansen, M., Kornum, Birgitte Rahbek, Rasmussen, L. K., Någren, K., Madsen, J., Begtrup, M. & Knudsen, Gitte Moos, 1 Nov 2010, In: Journal of Nuclear Medicine. 51, 11, p. 1763-1770

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Procedure guideline for brain perfusion SPECT using 99mTc radiopharmaceuticals 3.0

    Thomsen, G. & Knudsen, Gitte Moos, 1 Dec 2010, In: Journal of Nuclear Medicine Technology. 38, 4, p. 209

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Serotonin transporters in dopamine transporter imaging: a head-to-head comparison of dopamine transporter SPECT radioligands 123I-FP-CIT and 123I-PE2I

    Ziebell, M., Holm-Hansen, S., Thomsen, G., Wagner, A., Jensen, P., Pinborg, Lars Hageman & Knudsen, Gitte Moos, 1 Dec 2010, In: Journal of Nuclear Medicine. 51, 12, p. 1885-91 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2011
  17. Published

    11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements

    Ettrup, A., Mikkelsen, J. D., Lehel, S., Madsen, J., Nielsen, E. Ø., Palner, M., Timmermann, D. B., Peters, D. & Knudsen, Gitte Moos, 2011, In: Journal of Nuclear Medicine. 52, 9, p. 1449-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study

    Liu, X., Cannon, D. M., Akula, N., Moya, P. R., Knudsen, Gitte Moos, Arentzen, T., Steele, J., Laje, G., Drevets, W. C. & McMahon, F. J., 2011, In: Molecular Psychiatry. 16, 6, p. 584-5 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    An approach for serotonin depletion in pigs: effects on serotonin receptor binding

    Ettrup, A., Kornum, Birgitte Rahbek, Weikop, P. & Knudsen, Gitte Moos, 2011, In: Synapse. 65, 2, p. 136-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Blood BDNF concentrations reflect brain-tissue BDNF levels across species

    Klein, A. B., Williamson, R., Santini, M. A., Clemmensen, C., Ettrup, A., Rios, M., Knudsen, Gitte Moos & Aznar, S., 2011, In: International Journal of Neuropsychopharmacology. 14, 3, p. 347-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cerebral serotonin 4 receptors and amyloid-β in early Alzheimer's disease

    Madsen, K., Neumann, W., Holst, K. K., Marner, Lisbeth, Haahr, Mette Ewers, Lehel, S., Knudsen, Gitte Moos & Hasselbalch, Steen, 2011, In: Journal of Alzheimer's Disease. 26, 3, p. 457-66 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research

    Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 2011, In: Neuroscience & Biobehavioral Reviews. 35, 3, p. 437-51 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Depression and Alzheimer's disease: is stress the initiating factor in a common neuropathological cascade?

    Aznar, S. & Knudsen, Gitte Moos, 2011, In: Journal of Alzheimer's Disease. 23, 2, p. 177-93 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Effects of unilateral 6-OHDA lesions on [ <sup>3</sup>H]-N- propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat

    Palner, M., Kjærby, Celia, Knudsen, Gitte Moos & Cumming, P., 2011, In: Neurochemistry International.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat

    Palner, M., Kjaerby, C., Knudsen, Gitte Moos & Cumming, P., 2011, In: Neurochemistry International. 58, 3, p. 243-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Ex vivo evaluation of the serotonin 1A receptor partial agonist [³H]CUMI-101 in awake rats

    Palner, M., Underwood, M. D., Kumar, D. J. S., Arango, V., Knudsen, Gitte Moos, John Mann, J. & Parsey, R. V., 2011, In: Synapse. 65, 8, p. 715-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    HPA-axis tonus linked to hippocampal microstructural asymmetry

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frokjaer, V. G., Knudsen, Gitte Moos, Siebner, H. R. & Baaré, W. F. C., 2011. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  28. Published

    In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users

    Erritzoe, D., Frøkjær, V., Holst, K. K., Christoffersen, M., Johansen, S. S., Svarer, C., Madsen, J., Rasmussen, P. M., Ramsøy, T., Jernigan, T. L. & Knudsen, Gitte Moos, 2011, In: Archives of General Psychiatry. 68, 6, p. 562-76 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    In vivo imaging of cerebral serotonin transporter and serotonin2A receptor binding in 3,4 - methylenedioxymethamphetamine (MDMA or "Ecstasy") and hallucinogen users

    Erritzøe, D. F., Frøkjær, Vibe Gedsø, Holst, K. K., Christoffersen, M., Johansen, Sys Stybe, Svarer, C., Madsen, J., Rasmussen, P. M., Ramsøy, T., Jernigan, T. L. & Knudsen, Gitte Moos, 2011, In: Archives of General Psychiatry. 68, 6, p. 562-576 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Mass dose effects and in vivo affinity in brain PET receptor studies--a study of cerebral 5-HT4 receptor binding with [11C]SB207145

    Madsen, K., Marner, L., Haahr, M., Gillings, N. & Knudsen, Gitte Moos, 2011, In: Nuclear Medicine and Biology. 38, 8, p. 1085-91 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Novelty-induced activity-regulated cytoskeletal-associated protein (Arc) expression in frontal cortex requires serotonin 2A receptor activation

    Santini, M., Klein, A. B., El-Sayed, M., Ratner, C., Knudsen, Gitte Moos, Mikkelsen, J. D. & Aznar, S., 2011, In: Neuroscience. 190, p. 251-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers

    Ettrup, A., Hansen, M., Santini, M. A., Paine, J. S., Gillings, N., Palner, M., Lehel, S., Herth, M. M., Madsen, J., Kristensen, J., Begtrup, M. E. & Knudsen, Gitte Moos, 2011, In: European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 681-93 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Serotonin is involved in processing negative outcomes caused by low-risk decisions

    Macoveanu, J., Rowe, J. B., Hornboll, B., Knudsen, Gitte Moos, Paulson, O. B. & Siebner, H. R., 2011. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  34. Published

    Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine

    Rasmussen, H., Ebdrup, B. H., Erritzoe, D., Aggernaes, B., Oranje, B., Kalbitzer, J. G. M., Pinborg, Lars Hageman, Baaré, W. F. C., Svarer, C., Lublin, H., Knudsen, Gitte Moos & Glenthøj, Birte Yding, 2011, In: Psychopharmacology. 213, p. 583-592 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Synthesis and Biological Evaluation of 125I/123I-Labelled Analogues of Citalopram and Escitalopram as Potential Radioligands for Imaging of the Serotonin Transporter

    Madsen, J., Elfving, B., Frøkjær, V., Kornum, B. R., Thomsen, G., Martiny, L. & Knudsen, Gitte Moos, 2011, In: Journal of Labelled Compounds and Radiopharmaceuticals. 54, p. 185-190 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Validation of a method for accurate and highly reproducible quantification of brain dopamine transporter SPECT studies

    Jensen, P. S., Ziebell, M., Skouboe, G., Khalid, U., de Nijs, R., Thomsen, G., Knudsen, Gitte Moos & Svarer, C., 2011, In: Journal of Nuclear Medicine Technology. 39, 4, p. 271-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The Reduction of Baseline Serotonin 2A Receptors in Mild Cognitive Impairment is Stable at Two-year Follow-up

    Marner, Lisbeth, Knudsen, Gitte Moos, Madsen, K., Holm, S., Baaré, W., Hasselbalch, Steen & Holm, S., 1 Jan 2011, In: Journal of Alzheimer's Disease. 23, 3, p. 453-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Serotonin transporter binding in the hypothalamus correlates negatively with tonic heat pain ratings in healthy subjects: a [11C]DASB PET study

    Kupers, R., Frokjaer, V. G., Erritzoe, D., Naert, A., Budtz-Joergensen, Esben, Nielsen, F. A., Kehlet, Henrik & Knudsen, Gitte Moos, 15 Jan 2011, In: NeuroImage. 54, 2, p. 1336-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects

    Madsen, K., Erritzøe, D. F., Mortensen, Erik Lykke, Gade, A., Madsen, J., Baaré, W. F. C., Knudsen, Gitte Moos & Hasselbalch, Steen, 1 Feb 2011, In: Psychopharmacology. 213, 2-3, p. 573-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers

    Ettrup, A., Hansen, M., Santini, M. A., Paine, J. S., Gillings, N., Palner, M., Lehel, S., Herth, Matthias Manfred, Madsen, J., Kristensen, Jesper Langgaard, Begtrup, M. & Knudsen, Gitte Moos, 1 Apr 2011, In: European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 681-693

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB207145 PET study

    Madsen, K., Haahr, M. T., Marner, L., Keller, S. H., Baaré, W. F., Svarer, C., Hasselbalch, Steen & Knudsen, Gitte Moos, 1 Jun 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 6, p. 1475-81 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frokjaer, V. G., Knudsen, Gitte Moos, Mortensen, E. L. & Baaré, W. F. C., 4 Aug 2011. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  43. Published

    HPA-axis tonus linked to hippocampal microstructural asymmetry

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frøkjær, V., Knudsen, Gitte Moos, Siebner, H. R. & Baaré, W. F. C., 4 Aug 2011. 0 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  44. 2012
  45. Published

    Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frøkjær, Vibe Gedsø, Mortensen, Erik Lykke, Knudsen, Gitte Moos & Baaré, W. F. C., 2012, In: Psychiatry Research: Neuroimaging. 201, 1, p. 63-72 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT4 receptor levels

    Jennings, K. A., Licht, C. L., Bruce, A., Lesch, K., Knudsen, Gitte Moos & Sharp, T., 2012, In: International Journal of Neuropsychopharmacology. 15, 8, p. 1099-1107 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Lack of association between prior depressive episodes and cerebral [(11)C]PiB binding

    Madsen, K., Hasselbalch, B. J., Frederiksen, K. S., Haahr, M. E., Gade, A., Law, I., Price, J. C., Knudsen, Gitte Moos, Kessing, Lars Vedel & Hasselbalch, Steen, 2012, In: Neurobiology of Aging. 33, 12, p. 2334-2342

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: a combined [11C]DASB and [18F]altanserin-PET study

    Marner, Lisbeth, Frokjaer, V. G., Kalbitzer, J., Lehel, S., Madsen, K., Baaré, W. F. C., Knudsen, Gitte Moos & Hasselbalch, Steen, 2012, In: Neurobiology of Aging. 33, 3, p. 479-87

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Predictive value of dopamine transporter SPECT imaging with [(123)I]PE2I in patients with subtle parkinsonian symptoms

    Ziebell, M., Andersen, B. B., Thomsen, G., Pinborg, Lars Hageman, Karlsborg, M., Hasselbalch, Steen & Knudsen, Gitte Moos, 2012, In: European Journal of Nuclear Medicine and Molecular Imaging. 39, 2, p. 242-50 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Striatal dopamine transporter binding correlates with serum BDNF levels in patients with striatal dopaminergic neurodegeneration

    Ziebell, M., Khalid, U., Klein, A. B., Aznar, S., Thomsen, G., Jensen, P., Knudsen, Gitte Moos & Jensen, P. S., 2012, In: Neurobiology of Aging. 33, 2, p. 428.e1-428.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Synthesis and evaluation of [11C]Cimbi-806 as a potential PET ligand for 5-HT7 receptor imaging

    Herth, Matthias Manfred, Hansen, H. D., Ettrup, A. J., Dyssegaard, A., Lehel, S., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 2012, In: Bioorganic and Medicinal Chemistry. 20, 14, p. 4574-4581 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression

    Koefoed, P., Woldbye, D. P. D., Hansen, T. V. O., Eplov, L. F., Christiansen, S. H. O., Mors, O., Kessing, L. V., Werge, T., Kaipio, K., Pesonen, U., Fahmy, T., Mellerup, E. T., Jakobsen, K. D., Hansen, E. S., Knudsen, G. M., Bukh, J. D., Bock, C., Lindberg, C., Kristensen, A. S., Dam, H. & 6 others, Nordentoft, Merete, Als, T. D., Wang, A. G., Gether, Ulrik, Rehfeld, Jens Frederik & Bolwig, T. G., 23 Mar 2012, In: Acta Neuropsychiatrica. 24, 2, p. 81-90 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

    Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner, Hans, Frølund, Bente, Clausen, Rasmus Prætorius, Olsen, Jesper Velgaard, Knudsen, Gitte Moos, Chebib, M. & Wellendorph, Petrine, 14 Aug 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 6065