Gitte Moos Knudsen

Gitte Moos Knudsen

Clinical Professor

Member of:

  • Neurology


  1. 2014
  2. Published

    Serotonin 2A receptor agonist binding in the human brain with [C]Cimbi-36

    Ettrup, A., da Cunha-Bang, S., McMahon, B. P., Lehel, S., Dyssegaard, A., Skibsted, A. W., Jørgensen, Louise Møller, Hansen, M., Baandrup, A. O., Bache, S., Svarer, C., Kristensen, Jesper Langgaard, Gillings, N., Madsen, J. & Knudsen, Gitte Moos, 30 Apr 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, p. 1188-1196 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    (11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand

    Andersen, V. L., Hansen, H. D., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 19 Apr 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 11, p. 2408-2411 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    5-HT2A and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains

    Klein, A. B., Ultved, L., Adamsen, D., Santini, M. A., Tobeña, A., Fernandez-Teruel, A., Flores, P., Moreno, M., Cardona, D., Knudsen, Gitte Moos, Aznar, S. & Mikkelsen, Jens D., 28 Mar 2014, In: Neuroscience. 263, p. 36-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors

    Hansen, H. D., Herth, Matthias Manfred, Ettrup, A., Andersen, V. L., Lehel, S., Dyssegaard, A., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 24 Feb 2014, In: Journal of Nuclear Medicine. 55, 4, p. 640-646

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Imaging of the Serotonin System: Radiotracers and Applications in Memory Disorders

    Knudsen, Gitte Moos & Hasselbalch, S. G., 2014, PET and SPECT of Neurobiological Systems. Dierckx, R. A. J. O., Otte, A., de Vries, E. F. J., van Waarde, A. & Luiten, P. G. M. (eds.). Springer, p. 669-686 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. 2013
  8. Published

    Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice

    Jørgensen, C. V., Jacobsen, J. P., Caron, M. G., Klein, A. B., Knudsen, Gitte Moos & Mikkelsen, Jens D., 25 Oct 2013, In: Neuroscience Letters. 555, p. 118-22 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Playing it safe but losing anyway-Serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion

    Macoveanu, J., Rowe, J. B., Hornboll, B., Elliott, R., Paulson, Olaf B., Knudsen, Gitte Moos & Siebner, Hartwig Roman, 23 Aug 2013, In: European Neuropsychopharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Comparison of the 5-HT2A PET tracers, [F-18]MH.MZ and [F-18]altanserin

    Hansen, H., Herth, Matthias Manfred, Ettrup, A., Dyssegaard, A. & Knudsen, Gitte Moos, May 2013, p. S338-S338.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  11. Published

    Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia

    Santini, M. A., Ratner, C. F., Aznar, S., Klein, A. B., Knudsen, Gitte Moos, Mikkelsen, Jens D. & Klein, A. B., May 2013, In: Journal of Neuroscience Research. 91, 5, p. 634-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Synthesis and evaluation of [C-11]CIMBI-712 and [C-11]CIMBI-772

    Andersen, V. L., Herth, Matthias Manfred, Hansen, H. D., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, May 2013, p. S101-S101.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  13. Published

    5-HT radioligands for human brain imaging with PET and SPECT

    Paterson, L. M., Kornum, Birgitte Rahbek, Nutt, D. J., Pike, V. W. & Knudsen, Gitte Moos, Jan 2013, In: Medicinal Research Reviews. 33, 1, p. 54-111 58 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Development of a 11C-labeled tetrazine for rapid tetrazine–trans-cyclooctene ligation

    Herth, Matthias Manfred, Andersen, V. L., Lehel, S., Madsen, J., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Chemical Communications. 49, p. 3805-3807 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    No association between striatal dopamine transporter binding and body mass index: A multi-center European study in healthy volunteers

    van de Giessen, E., Hesse, S., Caan, M. W. A., Zientek, F., Dickson, J. C., Tossici-Bolt, L., Sera, T., Asenbaum, S., Guignard, R., Akdemir, U. O., Knudsen, Gitte Moos, Nobili, F., Pagani, M., Vander Borght, T., Van Laere, K., Varrone, A., Tatsch, K., Booij, J. & Sabri, O., 2013, In: NeuroImage. 64, p. 61-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Palladium-mediated conversion of para-aminoarylboronic esters into para-aminoaryl- 11C-methanes

    Andersen, V. L., Herth, Matthias Manfred, Lehel, S., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Tetrahedron Letters. 54, 3, p. 213-216 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Radiolabelling and PET brain imaging of the a1-adrenoceptor antagonist Lu AE43936

    Risgaard, R., Ettrup, A. J., Balle, T., Dyssegaard, A., Hansen, H. D., Lehel, S., Madsen, J., Pedersen, H., Püschl, A., Badolo, L., Bang-Andersen, B., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Nuclear Medicine & Biology. 40, 1, p. 135-140 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals

    da Cunha-Bang, S., Stenbæk, D. S., Holst, K., Licht, C. L., Jensen, P. S., Frokjaer, V. G., Mortensen, Erik Lykke & Knudsen, Gitte Moos, 2013, In: Psychiatry Research. 212, 2, p. 125-131 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2012
  20. Published

    Hypothalamic-pituitary-adrenal axis tonus is associated with hippocampal microstructural asymmetry

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frøkjær, Vibe Gedsø, Knudsen, Gitte Moos, Siebner, Hartwig Roman & Baaré, W. F. C., 15 Oct 2012, In: NeuroImage. 63, 1, p. 95-103 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Synthesis and In Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT7 Receptor Imaging with PET

    Herth, Matthias Manfred, Volk, B., Pallagi, K., Koefoed Bech, L., A. Antoni, F., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 31 Aug 2012, In: ACS Chemical Neuroscience. 3, 12, p. 1002-1007

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

    Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner, Hans, Frølund, Bente, Clausen, Rasmus Prætorius, Olsen, Jesper Velgaard, Knudsen, Gitte Moos, Chebib, M. & Wellendorph, Petrine, 14 Aug 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression

    Koefoed, P., Woldbye, D. P. D., Hansen, T. V. O., Eplov, L. F., Christiansen, S. H. O., Mors, O., Kessing, L. V., Werge, T., Kaipio, K., Pesonen, U., Fahmy, T., Mellerup, E. T., Jakobsen, K. D., Hansen, E. S., Knudsen, G. M., Bukh, J. D., Bock, C., Lindberg, C., Kristensen, A. S., Dam, H. & 6 others, Nordentoft, Merete, Als, T. D., Wang, A. G., Gether, Ulrik, Rehfeld, Jens Frederik & Bolwig, T. G., 23 Mar 2012, In: Acta Neuropsychiatrica. 24, 2, p. 81-90 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frøkjær, Vibe Gedsø, Mortensen, Erik Lykke, Knudsen, Gitte Moos & Baaré, W. F. C., 2012, In: Psychiatry Research: Neuroimaging. 201, 1, p. 63-72 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT4 receptor levels

    Jennings, K. A., Licht, C. L., Bruce, A., Lesch, K., Knudsen, Gitte Moos & Sharp, T., 2012, In: International Journal of Neuropsychopharmacology. 15, 8, p. 1099-1107 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Lack of association between prior depressive episodes and cerebral [(11)C]PiB binding

    Madsen, K., Hasselbalch, B. J., Frederiksen, K. S., Haahr, M. E., Gade, A., Law, I., Price, J. C., Knudsen, Gitte Moos, Kessing, Lars Vedel & Hasselbalch, Steen, 2012, In: Neurobiology of Aging. 33, 12, p. 2334-2342

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: a combined [11C]DASB and [18F]altanserin-PET study

    Marner, Lisbeth, Frokjaer, V. G., Kalbitzer, J., Lehel, S., Madsen, K., Baaré, W. F. C., Knudsen, Gitte Moos & Hasselbalch, Steen, 2012, In: Neurobiology of Aging. 33, 3, p. 479-87

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Predictive value of dopamine transporter SPECT imaging with [(123)I]PE2I in patients with subtle parkinsonian symptoms

    Ziebell, M., Andersen, B. B., Thomsen, G., Pinborg, Lars Hageman, Karlsborg, M., Hasselbalch, Steen & Knudsen, Gitte Moos, 2012, In: European Journal of Nuclear Medicine and Molecular Imaging. 39, 2, p. 242-50 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Striatal dopamine transporter binding correlates with serum BDNF levels in patients with striatal dopaminergic neurodegeneration

    Ziebell, M., Khalid, U., Klein, A. B., Aznar, S., Thomsen, G., Jensen, P., Knudsen, Gitte Moos & Jensen, P. S., 2012, In: Neurobiology of Aging. 33, 2, p. 428.e1-428.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Synthesis and evaluation of [11C]Cimbi-806 as a potential PET ligand for 5-HT7 receptor imaging

    Herth, Matthias Manfred, Hansen, H. D., Ettrup, A. J., Dyssegaard, A., Lehel, S., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 2012, In: Bioorganic and Medicinal Chemistry. 20, 14, p. 4574-4581 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2011
  32. Published

    Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frokjaer, V. G., Knudsen, Gitte Moos, Mortensen, E. L. & Baaré, W. F. C., 4 Aug 2011. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  33. Published

    HPA-axis tonus linked to hippocampal microstructural asymmetry

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frøkjær, V., Knudsen, Gitte Moos, Siebner, H. R. & Baaré, W. F. C., 4 Aug 2011. 0 p.

    Research output: Contribution to conferencePosterResearchpeer-review

  34. Published

    Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB207145 PET study

    Madsen, K., Haahr, M. T., Marner, L., Keller, S. H., Baaré, W. F., Svarer, C., Hasselbalch, Steen & Knudsen, Gitte Moos, 1 Jun 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 6, p. 1475-81 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers

    Ettrup, A., Hansen, M., Santini, M. A., Paine, J. S., Gillings, N., Palner, M., Lehel, S., Herth, Matthias Manfred, Madsen, J., Kristensen, Jesper Langgaard, Begtrup, M. & Knudsen, Gitte Moos, 1 Apr 2011, In: European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 681-693

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects

    Madsen, K., Erritzøe, D. F., Mortensen, Erik Lykke, Gade, A., Madsen, J., Baaré, W. F. C., Knudsen, Gitte Moos & Hasselbalch, Steen, 1 Feb 2011, In: Psychopharmacology. 213, 2-3, p. 573-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Serotonin transporter binding in the hypothalamus correlates negatively with tonic heat pain ratings in healthy subjects: a [11C]DASB PET study

    Kupers, R., Frokjaer, V. G., Erritzoe, D., Naert, A., Budtz-Joergensen, Esben, Nielsen, F. A., Kehlet, Henrik & Knudsen, Gitte Moos, 15 Jan 2011, In: NeuroImage. 54, 2, p. 1336-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The Reduction of Baseline Serotonin 2A Receptors in Mild Cognitive Impairment is Stable at Two-year Follow-up

    Marner, Lisbeth, Knudsen, Gitte Moos, Madsen, K., Holm, S., Baaré, W., Hasselbalch, Steen & Holm, S., 1 Jan 2011, In: Journal of Alzheimer's Disease. 23, 3, p. 453-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements

    Ettrup, A., Mikkelsen, J. D., Lehel, S., Madsen, J., Nielsen, E. Ø., Palner, M., Timmermann, D. B., Peters, D. & Knudsen, Gitte Moos, 2011, In: Journal of Nuclear Medicine. 52, 9, p. 1449-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study

    Liu, X., Cannon, D. M., Akula, N., Moya, P. R., Knudsen, Gitte Moos, Arentzen, T., Steele, J., Laje, G., Drevets, W. C. & McMahon, F. J., 2011, In: Molecular Psychiatry. 16, 6, p. 584-5 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    An approach for serotonin depletion in pigs: effects on serotonin receptor binding

    Ettrup, A., Kornum, Birgitte Rahbek, Weikop, P. & Knudsen, Gitte Moos, 2011, In: Synapse. 65, 2, p. 136-45 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Blood BDNF concentrations reflect brain-tissue BDNF levels across species

    Klein, A. B., Williamson, R., Santini, M. A., Clemmensen, C., Ettrup, A., Rios, M., Knudsen, Gitte Moos & Aznar, S., 2011, In: International Journal of Neuropsychopharmacology. 14, 3, p. 347-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Cerebral serotonin 4 receptors and amyloid-β in early Alzheimer's disease

    Madsen, K., Neumann, W., Holst, K. K., Marner, Lisbeth, Haahr, Mette Ewers, Lehel, S., Knudsen, Gitte Moos & Hasselbalch, Steen, 2011, In: Journal of Alzheimer's Disease. 26, 3, p. 457-66 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research

    Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 2011, In: Neuroscience & Biobehavioral Reviews. 35, 3, p. 437-51 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Depression and Alzheimer's disease: is stress the initiating factor in a common neuropathological cascade?

    Aznar, S. & Knudsen, Gitte Moos, 2011, In: Journal of Alzheimer's Disease. 23, 2, p. 177-93 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Effects of unilateral 6-OHDA lesions on [ <sup>3</sup>H]-N- propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat

    Palner, M., Kjærby, Celia, Knudsen, Gitte Moos & Cumming, P., 2011, In: Neurochemistry International.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat

    Palner, M., Kjaerby, C., Knudsen, Gitte Moos & Cumming, P., 2011, In: Neurochemistry International. 58, 3, p. 243-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Ex vivo evaluation of the serotonin 1A receptor partial agonist [³H]CUMI-101 in awake rats

    Palner, M., Underwood, M. D., Kumar, D. J. S., Arango, V., Knudsen, Gitte Moos, John Mann, J. & Parsey, R. V., 2011, In: Synapse. 65, 8, p. 715-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    HPA-axis tonus linked to hippocampal microstructural asymmetry

    Madsen, K. S., Jernigan, T. L., Iversen, P., Frokjaer, V. G., Knudsen, Gitte Moos, Siebner, H. R. & Baaré, W. F. C., 2011. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  50. Published

    In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users

    Erritzoe, D., Frøkjær, V., Holst, K. K., Christoffersen, M., Johansen, S. S., Svarer, C., Madsen, J., Rasmussen, P. M., Ramsøy, T., Jernigan, T. L. & Knudsen, Gitte Moos, 2011, In: Archives of General Psychiatry. 68, 6, p. 562-76 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    In vivo imaging of cerebral serotonin transporter and serotonin2A receptor binding in 3,4 - methylenedioxymethamphetamine (MDMA or "Ecstasy") and hallucinogen users

    Erritzøe, D. F., Frøkjær, Vibe Gedsø, Holst, K. K., Christoffersen, M., Johansen, Sys Stybe, Svarer, C., Madsen, J., Rasmussen, P. M., Ramsøy, T., Jernigan, T. L. & Knudsen, Gitte Moos, 2011, In: Archives of General Psychiatry. 68, 6, p. 562-576 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Mass dose effects and in vivo affinity in brain PET receptor studies--a study of cerebral 5-HT4 receptor binding with [11C]SB207145

    Madsen, K., Marner, L., Haahr, M., Gillings, N. & Knudsen, Gitte Moos, 2011, In: Nuclear Medicine and Biology. 38, 8, p. 1085-91 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Novelty-induced activity-regulated cytoskeletal-associated protein (Arc) expression in frontal cortex requires serotonin 2A receptor activation

    Santini, M., Klein, A. B., El-Sayed, M., Ratner, C., Knudsen, Gitte Moos, Mikkelsen, J. D. & Aznar, S., 2011, In: Neuroscience. 190, p. 251-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers

    Ettrup, A., Hansen, M., Santini, M. A., Paine, J. S., Gillings, N., Palner, M., Lehel, S., Herth, M. M., Madsen, J., Kristensen, J., Begtrup, M. E. & Knudsen, Gitte Moos, 2011, In: European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 681-93 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 6065