Gitte Moos Knudsen
Clinical Professor
- 2014
- Published
Serotonin 2A receptor agonist binding in the human brain with [C]Cimbi-36
Ettrup, A., da Cunha-Bang, S., McMahon, B. P., Lehel, S., Dyssegaard, A., Skibsted, A. W., Jørgensen, Louise Møller, Hansen, M., Baandrup, A. O., Bache, S., Svarer, C., Kristensen, Jesper Langgaard, Gillings, N., Madsen, J. & Knudsen, Gitte Moos, 30 Apr 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, p. 1188-1196 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
(11)C-labeling and preliminary evaluation of vortioxetine as a PET radioligand
Andersen, V. L., Hansen, H. D., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 19 Apr 2014, In: Bioorganic & Medicinal Chemistry Letters. 24, 11, p. 2408-2411 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
5-HT2A and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains
Klein, A. B., Ultved, L., Adamsen, D., Santini, M. A., Tobeña, A., Fernandez-Teruel, A., Flores, P., Moreno, M., Cardona, D., Knudsen, Gitte Moos, Aznar, S. & Mikkelsen, Jens D., 28 Mar 2014, In: Neuroscience. 263, p. 36-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors
Hansen, H. D., Herth, Matthias Manfred, Ettrup, A., Andersen, V. L., Lehel, S., Dyssegaard, A., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 24 Feb 2014, In: Journal of Nuclear Medicine. 55, 4, p. 640-646Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Imaging of the Serotonin System: Radiotracers and Applications in Memory Disorders
Knudsen, Gitte Moos & Hasselbalch, S. G., 2014, PET and SPECT of Neurobiological Systems. Dierckx, R. A. J. O., Otte, A., de Vries, E. F. J., van Waarde, A. & Luiten, P. G. M. (eds.). Springer, p. 669-686 18 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2013
- Published
Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice
Jørgensen, C. V., Jacobsen, J. P., Caron, M. G., Klein, A. B., Knudsen, Gitte Moos & Mikkelsen, Jens D., 25 Oct 2013, In: Neuroscience Letters. 555, p. 118-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Playing it safe but losing anyway-Serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion
Macoveanu, J., Rowe, J. B., Hornboll, B., Elliott, R., Paulson, Olaf B., Knudsen, Gitte Moos & Siebner, Hartwig Roman, 23 Aug 2013, In: European Neuropsychopharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the 5-HT2A PET tracers, [F-18]MH.MZ and [F-18]altanserin
Hansen, H., Herth, Matthias Manfred, Ettrup, A., Dyssegaard, A. & Knudsen, Gitte Moos, May 2013, p. S338-S338.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia
Santini, M. A., Ratner, C. F., Aznar, S., Klein, A. B., Knudsen, Gitte Moos, Mikkelsen, Jens D. & Klein, A. B., May 2013, In: Journal of Neuroscience Research. 91, 5, p. 634-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and evaluation of [C-11]CIMBI-712 and [C-11]CIMBI-772
Andersen, V. L., Herth, Matthias Manfred, Hansen, H. D., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, May 2013, p. S101-S101.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
5-HT radioligands for human brain imaging with PET and SPECT
Paterson, L. M., Kornum, Birgitte Rahbek, Nutt, D. J., Pike, V. W. & Knudsen, Gitte Moos, Jan 2013, In: Medicinal Research Reviews. 33, 1, p. 54-111 58 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Development of a 11C-labeled tetrazine for rapid tetrazine–trans-cyclooctene ligation
Herth, Matthias Manfred, Andersen, V. L., Lehel, S., Madsen, J., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Chemical Communications. 49, p. 3805-3807 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No association between striatal dopamine transporter binding and body mass index: A multi-center European study in healthy volunteers
van de Giessen, E., Hesse, S., Caan, M. W. A., Zientek, F., Dickson, J. C., Tossici-Bolt, L., Sera, T., Asenbaum, S., Guignard, R., Akdemir, U. O., Knudsen, Gitte Moos, Nobili, F., Pagani, M., Vander Borght, T., Van Laere, K., Varrone, A., Tatsch, K., Booij, J. & Sabri, O., 2013, In: NeuroImage. 64, p. 61-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Palladium-mediated conversion of para-aminoarylboronic esters into para-aminoaryl- 11C-methanes
Andersen, V. L., Herth, Matthias Manfred, Lehel, S., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Tetrahedron Letters. 54, 3, p. 213-216 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiolabelling and PET brain imaging of the a1-adrenoceptor antagonist Lu AE43936
Risgaard, R., Ettrup, A. J., Balle, T., Dyssegaard, A., Hansen, H. D., Lehel, S., Madsen, J., Pedersen, H., Püschl, A., Badolo, L., Bang-Andersen, B., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Nuclear Medicine & Biology. 40, 1, p. 135-140 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals
da Cunha-Bang, S., Stenbæk, D. S., Holst, K., Licht, C. L., Jensen, P. S., Frokjaer, V. G., Mortensen, Erik Lykke & Knudsen, Gitte Moos, 2013, In: Psychiatry Research. 212, 2, p. 125-131 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Hypothalamic-pituitary-adrenal axis tonus is associated with hippocampal microstructural asymmetry
Madsen, K. S., Jernigan, T. L., Iversen, P., Frøkjær, Vibe Gedsø, Knudsen, Gitte Moos, Siebner, Hartwig Roman & Baaré, W. F. C., 15 Oct 2012, In: NeuroImage. 63, 1, p. 95-103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and In Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT7 Receptor Imaging with PET
Herth, Matthias Manfred, Volk, B., Pallagi, K., Koefoed Bech, L., A. Antoni, F., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 31 Aug 2012, In: ACS Chemical Neuroscience. 3, 12, p. 1002-1007Research output: Contribution to journal › Journal article › Research › peer-review
- Published
α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)
Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner, Hans, Frølund, Bente, Clausen, Rasmus Prætorius, Olsen, Jesper Velgaard, Knudsen, Gitte Moos, Chebib, M. & Wellendorph, Petrine, 14 Aug 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Koefoed, P., Woldbye, D. P. D., Hansen, T. V. O., Eplov, L. F., Christiansen, S. H. O., Mors, O., Kessing, L. V., Werge, T., Kaipio, K., Pesonen, U., Fahmy, T., Mellerup, E. T., Jakobsen, K. D., Hansen, E. S., Knudsen, G. M., Bukh, J. D., Bock, C., Lindberg, C., Kristensen, A. S., Dam, H. & 6 others, , 23 Mar 2012, In: Acta Neuropsychiatrica. 24, 2, p. 81-90 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture
Madsen, K. S., Jernigan, T. L., Iversen, P., Frøkjær, Vibe Gedsø, Mortensen, Erik Lykke, Knudsen, Gitte Moos & Baaré, W. F. C., 2012, In: Psychiatry Research: Neuroimaging. 201, 1, p. 63-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in 5-hydroxytryptamine transporter expression causes adaptive changes in 5-HT4 receptor levels
Jennings, K. A., Licht, C. L., Bruce, A., Lesch, K., Knudsen, Gitte Moos & Sharp, T., 2012, In: International Journal of Neuropsychopharmacology. 15, 8, p. 1099-1107 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of association between prior depressive episodes and cerebral [(11)C]PiB binding
Madsen, K., Hasselbalch, B. J., Frederiksen, K. S., Haahr, M. E., Gade, A., Law, I., Price, J. C., Knudsen, Gitte Moos, Kessing, Lars Vedel & Hasselbalch, Steen, 2012, In: Neurobiology of Aging. 33, 12, p. 2334-2342Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of serotonin 2A receptors exceeds loss of serotonergic projections in early Alzheimer's disease: a combined [11C]DASB and [18F]altanserin-PET study
Marner, Lisbeth, Frokjaer, V. G., Kalbitzer, J., Lehel, S., Madsen, K., Baaré, W. F. C., Knudsen, Gitte Moos & Hasselbalch, Steen, 2012, In: Neurobiology of Aging. 33, 3, p. 479-87Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictive value of dopamine transporter SPECT imaging with [(123)I]PE2I in patients with subtle parkinsonian symptoms
Ziebell, M., Andersen, B. B., Thomsen, G., Pinborg, Lars Hageman, Karlsborg, M., Hasselbalch, Steen & Knudsen, Gitte Moos, 2012, In: European Journal of Nuclear Medicine and Molecular Imaging. 39, 2, p. 242-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Striatal dopamine transporter binding correlates with serum BDNF levels in patients with striatal dopaminergic neurodegeneration
Ziebell, M., Khalid, U., Klein, A. B., Aznar, S., Thomsen, G., Jensen, P., Knudsen, Gitte Moos & Jensen, P. S., 2012, In: Neurobiology of Aging. 33, 2, p. 428.e1-428.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and evaluation of [11C]Cimbi-806 as a potential PET ligand for 5-HT7 receptor imaging
Herth, Matthias Manfred, Hansen, H. D., Ettrup, A. J., Dyssegaard, A., Lehel, S., Kristensen, Jesper Langgaard & Knudsen, Gitte Moos, 2012, In: Bioorganic and Medicinal Chemistry. 20, 14, p. 4574-4581 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Cortisol awakening response and negative emotionality linked to asymmetry in major limbic fibre bundle architecture
Madsen, K. S., Jernigan, T. L., Iversen, P., Frokjaer, V. G., Knudsen, Gitte Moos, Mortensen, E. L. & Baaré, W. F. C., 4 Aug 2011. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
HPA-axis tonus linked to hippocampal microstructural asymmetry
Madsen, K. S., Jernigan, T. L., Iversen, P., Frøkjær, V., Knudsen, Gitte Moos, Siebner, H. R. & Baaré, W. F. C., 4 Aug 2011. 0 p.Research output: Contribution to conference › Poster › Research › peer-review
- Published
Age and sex effects on 5-HT(4) receptors in the human brain: a [(11)C]SB207145 PET study
Madsen, K., Haahr, M. T., Marner, L., Keller, S. H., Baaré, W. F., Svarer, C., Hasselbalch, Steen & Knudsen, Gitte Moos, 1 Jun 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 6, p. 1475-81 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers
Ettrup, A., Hansen, M., Santini, M. A., Paine, J. S., Gillings, N., Palner, M., Lehel, S., Herth, Matthias Manfred, Madsen, J., Kristensen, Jesper Langgaard, Begtrup, M. & Knudsen, Gitte Moos, 1 Apr 2011, In: European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 681-693Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive function is related to fronto-striatal serotonin transporter levels--a brain PET study in young healthy subjects
Madsen, K., Erritzøe, D. F., Mortensen, Erik Lykke, Gade, A., Madsen, J., Baaré, W. F. C., Knudsen, Gitte Moos & Hasselbalch, Steen, 1 Feb 2011, In: Psychopharmacology. 213, 2-3, p. 573-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serotonin transporter binding in the hypothalamus correlates negatively with tonic heat pain ratings in healthy subjects: a [11C]DASB PET study
Kupers, R., Frokjaer, V. G., Erritzoe, D., Naert, A., Budtz-Joergensen, Esben, Nielsen, F. A., Kehlet, Henrik & Knudsen, Gitte Moos, 15 Jan 2011, In: NeuroImage. 54, 2, p. 1336-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Reduction of Baseline Serotonin 2A Receptors in Mild Cognitive Impairment is Stable at Two-year Follow-up
Marner, Lisbeth, Knudsen, Gitte Moos, Madsen, K., Holm, S., Baaré, W., Hasselbalch, Steen & Holm, S., 1 Jan 2011, In: Journal of Alzheimer's Disease. 23, 3, p. 453-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
11C-NS14492 as a novel PET radioligand for imaging cerebral alpha7 nicotinic acetylcholine receptors: in vivo evaluation and drug occupancy measurements
Ettrup, A., Mikkelsen, J. D., Lehel, S., Madsen, J., Nielsen, E. Ø., Palner, M., Timmermann, D. B., Peters, D. & Knudsen, Gitte Moos, 2011, In: Journal of Nuclear Medicine. 52, 9, p. 1449-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study
Liu, X., Cannon, D. M., Akula, N., Moya, P. R., Knudsen, Gitte Moos, Arentzen, T., Steele, J., Laje, G., Drevets, W. C. & McMahon, F. J., 2011, In: Molecular Psychiatry. 16, 6, p. 584-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An approach for serotonin depletion in pigs: effects on serotonin receptor binding
Ettrup, A., Kornum, Birgitte Rahbek, Weikop, P. & Knudsen, Gitte Moos, 2011, In: Synapse. 65, 2, p. 136-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood BDNF concentrations reflect brain-tissue BDNF levels across species
Klein, A. B., Williamson, R., Santini, M. A., Clemmensen, C., Ettrup, A., Rios, M., Knudsen, Gitte Moos & Aznar, S., 2011, In: International Journal of Neuropsychopharmacology. 14, 3, p. 347-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral serotonin 4 receptors and amyloid-β in early Alzheimer's disease
Madsen, K., Neumann, W., Holst, K. K., Marner, Lisbeth, Haahr, Mette Ewers, Lehel, S., Knudsen, Gitte Moos & Hasselbalch, Steen, 2011, In: Journal of Alzheimer's Disease. 26, 3, p. 457-66 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research
Kornum, Birgitte Rahbek & Knudsen, Gitte Moos, 2011, In: Neuroscience & Biobehavioral Reviews. 35, 3, p. 437-51 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depression and Alzheimer's disease: is stress the initiating factor in a common neuropathological cascade?
Aznar, S. & Knudsen, Gitte Moos, 2011, In: Journal of Alzheimer's Disease. 23, 2, p. 177-93 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of unilateral 6-OHDA lesions on [ <sup>3</sup>H]-N- propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat
Palner, M., Kjærby, Celia, Knudsen, Gitte Moos & Cumming, P., 2011, In: Neurochemistry International.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat
Palner, M., Kjaerby, C., Knudsen, Gitte Moos & Cumming, P., 2011, In: Neurochemistry International. 58, 3, p. 243-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ex vivo evaluation of the serotonin 1A receptor partial agonist [³H]CUMI-101 in awake rats
Palner, M., Underwood, M. D., Kumar, D. J. S., Arango, V., Knudsen, Gitte Moos, John Mann, J. & Parsey, R. V., 2011, In: Synapse. 65, 8, p. 715-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HPA-axis tonus linked to hippocampal microstructural asymmetry
Madsen, K. S., Jernigan, T. L., Iversen, P., Frokjaer, V. G., Knudsen, Gitte Moos, Siebner, H. R. & Baaré, W. F. C., 2011. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users
Erritzoe, D., Frøkjær, V., Holst, K. K., Christoffersen, M., Johansen, S. S., Svarer, C., Madsen, J., Rasmussen, P. M., Ramsøy, T., Jernigan, T. L. & Knudsen, Gitte Moos, 2011, In: Archives of General Psychiatry. 68, 6, p. 562-76 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo imaging of cerebral serotonin transporter and serotonin2A receptor binding in 3,4 - methylenedioxymethamphetamine (MDMA or "Ecstasy") and hallucinogen users
Erritzøe, D. F., Frøkjær, Vibe Gedsø, Holst, K. K., Christoffersen, M., Johansen, Sys Stybe, Svarer, C., Madsen, J., Rasmussen, P. M., Ramsøy, T., Jernigan, T. L. & Knudsen, Gitte Moos, 2011, In: Archives of General Psychiatry. 68, 6, p. 562-576 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mass dose effects and in vivo affinity in brain PET receptor studies--a study of cerebral 5-HT4 receptor binding with [11C]SB207145
Madsen, K., Marner, L., Haahr, M., Gillings, N. & Knudsen, Gitte Moos, 2011, In: Nuclear Medicine and Biology. 38, 8, p. 1085-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novelty-induced activity-regulated cytoskeletal-associated protein (Arc) expression in frontal cortex requires serotonin 2A receptor activation
Santini, M., Klein, A. B., El-Sayed, M., Ratner, C., Knudsen, Gitte Moos, Mikkelsen, J. D. & Aznar, S., 2011, In: Neuroscience. 190, p. 251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT (2A) agonist PET tracers
Ettrup, A., Hansen, M., Santini, M. A., Paine, J. S., Gillings, N., Palner, M., Lehel, S., Herth, M. M., Madsen, J., Kristensen, J., Begtrup, M. E. & Knudsen, Gitte Moos, 2011, In: European Journal of Nuclear Medicine and Molecular Imaging. 38, 4, p. 681-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 6065
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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The Bipolar Illness Onset study: research protocol for the BIO cohort study
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Design of Infusion Schemes for Neuroreceptor Imaging: Application to [(11)C]Flumazenil-PET Steady-State Study
Research output: Contribution to journal › Journal article › Research › peer-review
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