Niels Erik Skakkebæk

Niels Erik Skakkebæk

Affiliate Professor

Member of:

  • Paediatrics


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  1. Published

    45,X/46,XY mosaicism: phenotypic characteristics, growth, and reproductive function--a retrospective longitudinal study

    Lindhardt Johansen, M., Hagen, C. P., Rajpert-De Meyts, E., Kjærgaard, S., Petersen, B. L., Skakkebæk, Niels Erik, Main, Katharina Maria & Juul, Anders, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 8, p. E1540-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    47,XXY Klinefelter syndrome: clinical characteristics and age-specific recommendations for medical management

    Aksglaede, L., Link, K., Giwercman, A., Jørgensen, N., Skakkebæk, Niels Erik & Juul, Anders, 2013, In: American Journal of Medical Genetics. Part C: Seminars in Medical Genetics. 163, 1, p. 55-63 9 p.

    Research output: Contribution to journal › Journal article › Research

  3. Published

    In vitro investigation of endocrine disrupting effects of pesticides on Ca2+-signaling in human sperm cells through actions on the sperm-specific and steroid-activated CatSper Ca2+-channel

    Birch, Michala Rosa, Johansen, M., Skakkebæk, Niels Erik, Andersson, A. & Rehfeld, Anders Aagaard, 2022, In: Environment International. 167, 15 p., 107399.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A Brief Review of the Link between Environment and Male Reproductive Health: Lessons from Studies of Testicular Germ Cell Cancer

    Skakkebæk, Niels Erik, 2016, In: Hormone Research in Paediatrics. 86, 4, p. 240-246 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    A controlled study on serum insulin-like growth factor-I and urinary excretion of growth hormone in fibromyalgia

    Jacobsen, S., Main, Katharina Maria, Danneskiold-Samsøe, B. & Skakkebæk, Niels Erik, 1 Jun 1995, In: Journal of Rheumatology. 22, 6, p. 1138-40 3 p.

    Research output: Contribution to journal › Journal article › Research

  6. Published

    A crossover-crossback prospective study of dibutyl-phthalate exposure from mesalamine medications and semen quality in men with inflammatory bowel disease

    Nassan, F. L., Coull, B. A., Skakkebæk, Niels Erik, Williams, M. A., Dadd, R., Mínguez-Alarcón, L., Krawetz, S. A., Hait, E. J., Korzenik, J. R., Moss, A. C., Ford, J. B. & Hauser, R., Oct 2016, In: Environment International. 95, p. 120-30 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A crossover-crossback prospective study of dibutyl-phthalate exposure from mesalamine medications and serum reproductive hormones in men

    Nassan, F. L., Coull, B. A., Skakkebæk, Niels Erik, Andersson, A., Williams, M. A., Mínguez-Alarcón, L., Krawetz, S. A., Hall, J. E., Hait, E. J., Korzenik, J. R., Ford, J. B., Moss, A. C. & Hauser, R., 2018, In: Environmental Research. 160, p. 121-131 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A history of cryptorchidism is associated with impaired testicular function in early adulthood: a cross-sectional study of 6376 men from the general population

    Koch, T., Hansen, A. H., Priskorn, L., Petersen, Jørgen Holm, Carlsen, E., Main, Katharina Maria, Skakkebæk, Niels Erik & Jørgensen, N., 2020, In: Human Reproduction. 35, 8, p. 1765-1780 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth

    Chellakooty, M., Vangsgaard, K., Larsen, T., Scheike, T., Falck-Larsen, J., Legarth, J., Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 1, p. 384-91 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples

    Nielsen, J. E., Kristensen, D. M., Almstrup, Kristian, Jørgensen, A., Olesen, I. A., Jacobsen, G. K., Horn, T., Skakkebæk, Niels Erik, Leffers, H., Rajpert-De Meyts, E. & Jacobsen, G., 2012, In: Andrologia. p. 78-85 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A prospective study of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in 942 healthy infants: associations with birth weight, gender, growth velocity, and breastfeeding

    Chellakooty, M., Juul, A., Boisen, K. A., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Main, K. M., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 820-826 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2γ in semen samples: Case report

    Høi-Hansen, Christina Engel, Rajpert-De Meyts, E., Carlsen, E., Almstrup, Kristian, Leffers, H. & Skakkebæk, Niels Erik, Mar 2005, In: Human Reproduction. 20, 3, p. 579-582 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF)-I, IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the Y chromosome (SRY)-positive 46,XX karyotypes

    Aksglaede, L., Skakkebæk, Niels Erik & Juul, Anders, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 1, p. 169-176 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Abundance of DLK1, differential expression of CYP11B1, CYP21A2 and MC2R, and lack of INSL3 distinguish testicular adrenal rest tumours from Leydig cell tumours

    Lottrup, G., Nielsen, J. E., Skakkebæk, Niels Erik, Juul, Anders & Rajpert-De Meyts, E., Apr 2015, In: European Journal of Endocrinology. 172, 4, p. 491-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Acquired cryptorchidism is frequent in infancy and childhood

    Wohlfahrt-Veje, C., Boisen, K. A., Boas, M., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Chellakooty, M., Suomi, A., Toppari, J., Skakkebæk, Niels Erik & Main, Katharina Maria, 2009, In: International Journal of Andrology. 32, 4, p. 423-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Adult Growth Hormone Deficiency

    Jørgensen, J., Müller, J., Wolthers, T., Vahn, N., Juul, Anders & Skakkebæk, Niels Erik, 1994, In: Hormone Research. 42, p. 235-241 6 p.

    Research output: Contribution to journal › Review › Research

  17. Published

    Adverse trends in male reproductive health: we may have reached a crucial 'tipping point'

    Andersson, A., Jørgensen, N., Main, Katharina Maria, Toppari, J., Rajpert-De Meyts, E., Leffers, H., Juul, Anders, Jensen, T. K. & Skakkebæk, Niels Erik, 2008, In: International Journal of Andrology. 31, 2, p. 74-80 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Adverse trends in male reproductive health and decreasing fertility rates

    Priskorn, L., Holmboe, S., Jørgensen, N., Andersson, A., Almstrup, Kristian, Toppari, J. & Skakkebæk, Niels Erik, 2012, In: Animal Reproduction Science. 31, 2, p. 760-771 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Age at voice break in Danish boys: effects of pre-pubertal body mass index and secular trend

    Juul, Anders, Magnusdottir, S., Scheike, T., Prytz, S. & Skakkebæk, Niels Erik, 1 Dec 2007, In: International Journal of Andrology. 30, 6, p. 537-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    An audit of the insulin-tolerance test in 255 patients with pituitary disease

    Lange, M., Svendsen, Ole Lander, Skakkebæk, Niels Erik, Müller, J., Juul, Anders, Schmiegelow, M. & Feldt-Rasmussen, Ulla, 2002, In: European Journal of Endocrinology. 147, 1, p. 41-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    An update on semen quality among young Finnish men and comparison with Danish data

    Rodprasert, W., Virtanen, H. E., Sadov, S., Perheentupa, A., Skakkebæk, Niels Erik, Jørgensen, N. & Toppari, J., 2019, In: Andrology. 7, 1, p. 15-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Analysis of cell-type-specific gene expression during mouse spermatogenesis

    Almstrup, Kristian, Nielsen, J. E., Hansen, M. A., Tanaka, M., Skakkebæk, Niels Erik & Leffers, H., Jun 2004, In: Biology of Reproduction. 70, 6, p. 1751-1761 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Analysis of gene expression in normal and neoplastic human testis: new roles of RNA

    Novotny, G. W., Nielsen, J. E., Sonne, Si Brask, Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Leffers, H. & Sonne, Si Brask, 2007, In: International Journal of Andrology. 30, 4, p. 316-327

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte

    Sonne, Si Brask, Almstrup, Kristian, Dalgaard, M., Juncker, A. S., Edsgard, D., Ruban, L., Harrison, N. J., Schwager, C., Abdollahi, A., Huber, P. E., Brunak, Søren, Gjerdrum, L. M., Moore, H. D., Andrews, P. W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jun 2009, In: Current Cancer Research. 69, 12, p. 5241-50 10 p.

    Research output: Contribution to journal › Journal article › Research

  25. Published

    Analysis of the sex-determining region of the Y chromosome (SRY) in sex reversed patients: point-mutation in SRY causing sex-reversion in a 46,XY female

    Müller, J., Schwartz, M. & Skakkebæk, Niels Erik, 1 Jul 1992, In: Journal of Clinical Endocrinology and Metabolism. 75, 1, p. 331-3 3 p.

    Research output: Contribution to journal › Journal article › Research

  26. Published

    Androgens and the ageing male

    Juul, Anders & Skakkebæk, Niels Erik, 2002, In: Human Reproduction Update. 8, 5, p. 423-33 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Anogenital distance as a phenotypic signature through infancy

    Priskorn, L., Petersen, Jørgen Holm, Jørgensen, N., Kyhl, H. B., Andersen, M. S., Main, Katharina Maria, Andersson, A., Skakkebæk, Niels Erik & Jensen, T. K., 2018, In: Pediatric Research. 83, 3, p. 573-579 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population

    Priskorn, L., Bang, A. K., Nordkap, L., Krause, M., Mendiola, J., Jensen, T. K., Juul, Anders, Skakkebæk, Niels Erik, Swan, S. H. & Jørgensen, Niklas Rye, 1 Jan 2019, In: Human reproduction (Oxford, England). 34, 1, p. 12-24 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview

    Jensen, T. K., Skakkebæk, Niels Erik, Jørgensen, N., Jensen, M. B. & Juul, Anders, 2011, In: Ugeskrift for Laeger. 173, 50, p. 3253-5 3 p.

    Research output: Contribution to journal › Comment/debate › Research

  30. Published

    Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method

    Courant, F., Aksglæde, L., Antignac, J., Monteau, F., Sørensen, K., Andersson, A., Skakkebæk, Niels Erik, Juul, Anders & Bizec, B. L., 1 Jan 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 82-92 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Association Between Use of Marijuana and Male Reproductive Hormones and Semen Quality: A Study Among 1,215 Healthy Young Men

    Gundersen, T. D., Jørgensen, N., Andersson, A., Bang, A. K., Nordkap, L., Skakkebæk, Niels Erik, Priskorn, L., Juul, Anders & Jensen, T. K., 2015, In: American Journal of Epidemiology. 182, 6, p. 473-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Association between chemical pattern in breast milk and congenital cryptorchidism: modelling of complex human exposures

    Krysiak-Baltyn, K., Toppari, J., Skakkebæk, Niels Erik, Jensen, T. S., Virtanen, H. E., Schramm, K., Shen, H., Vartiainen, T., Kiviranta, H., Taboureau, O., Audouze, K. M. L., Brunak, Søren & Main, Katharina Maria, 2012, In: International Journal of Andrology. 35, 3, p. 294-302 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Association between levels of persistent organic pollutants in adipose tissue and cryptorchidism in early childhood: a case-control study

    Koskenniemi, J. J., Virtanen, H. E., Kiviranta, H., Damgaard, I. N., Matomäki, J., Thorup, Jørgen Mogens, Hurme, T., Skakkebæk, Niels Erik, Main, Katharina Maria & Toppari, J., 2015, In: Environmental Health. 14, p. 78 1 p.

    Research output: Contribution to journal › Journal article › Research

  34. Published

    Association between organic dietary choice during pregnancy and hypospadias in offspring: a study of mothers of 306 boys operated on for hypospadias

    Christensen, J. S., Asklund, C., Skakkebæk, Niels Erik, Jørgensen, N., Andersen, H. R., Jørgensen, T. M., Olsen, L. H., Høyer, A. P., Moesgaard, J., Thorup, Jørgen Mogens & Jensen, T. K., Mar 2013, In: The Journal of Urology (Italian Edition). 189, 3, p. 1077-82 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Association between testicular dysgenesis syndrome (TDS) and testicular neoplasia: evidence from 20 adult patients with signs of maldevelopment of the testis

    Skakkebæk, Niels Erik, Holm, M., Hoei-Hansen, C., Jørgensen, N. & Rajpert-De Meyts, E., 1 Jan 2003, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 111, 1, p. 1-9; discussion 9-11

    Research output: Contribution to journal › Journal article › Research

  36. Published

    Association of in Utero Persistent Organic Pollutant Exposure with Placental Thyroid Hormones

    Li, Z. M., Hernandez-Moreno, D., Main, Katharina Maria, Skakkebæk, Niels Erik, Kiviranta, H., Toppari, J., Feldt-Rasmussen, Ulla, Shen, H., Schramm, K. W. & De Angelis, M., 2018, In: Endocrinology. 159, 10, p. 3473-3481 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries

    Jensen, T. K., Jørgensen, N., Punab, M., Haugen, T. B., Suominen, J., Zilaitiene, B., Horte, A., Andersen, A., Carlsen, E., Magnus, Ø., Matulevicius, V., Nermoen, I., Vierula, M., Keiding, N., Toppari, J. & Skakkebæk, Niels Erik, 2004, In: American Journal of Epidemiology. 159, 1, p. 49-58 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer

    Jensen, Martin Blomberg, Leffers, H., Petersen, Jørgen Holm, Daugaard, G., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 2008, In: Annals of Oncology. 19, 11, p. 1910-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Associations between congenital cryptorchidism in newborn boys and levels of dioxins and PCBs in placenta

    Virtanen, H. E., Koskenniemi, J. J., Sundqvist, E., Main, Katharina Maria, Kiviranta, H., Tuomisto, J. T., Tuomisto, J., Viluksela, M., Vartiainen, T., Skakkebæk, Niels Erik & Toppari, J., 2012, In: International Journal of Andrology. 35, 3, p. 283-93 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Associations of Filaggrin Gene Loss-of-Function Variants with Urinary Phthalate Metabolites and Testicular Function in Young Danish Men

    Joensen, U. N., Jørgensen, N., Meldgaard, M., Frederiksen, H., Andersson, A., Menné, T., Johansen, Jeanne Duus, Carlsen, B. C., Stender, S., Szecsi, P. B., Skakkebæk, Niels Erik, De Meyts, E. R. & Thyssen, Jacob Pontoppidan, Apr 2014, In: Environmental Health Perspectives. 122, 4, p. 345-350 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Assumed non-persistent environmental chemicals in human adipose tissue; matrix stability and correlation with levels measured in urine and serum

    Artacho-Cordón, F., Arrebola, J. P., Nielsen, O., Hernández, P., Skakkebæk, Niels Erik, Fernández, M. F., Andersson, A. M., Olea, N. & Frederiksen, H., Jul 2017, In: Environmental Research. 156, p. 120-127 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Authors' reply

    Keiding, N. & Skakkebæk, Niels Erik, 26 Aug 1995, In: BMJ. 311, p. 570-570 1 p.

    Research output: Contribution to journal › Comment/debate › Research

  43. Published

    Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years

    Priskorn, L., Nordkap, L., Bang, A. K., Krause, M., Holmboe, S. A., Egeberg Palme, D. L., Winge, S. B., Mørup, N., Carlsen, E., Joensen, Ulla Nordström, Blomberg Jensen, M., Main, Katharina Maria, Juul, Anders, Skakkebæk, Niels Erik, Jensen, T. K. & Jørgensen, N., 2018, In: Human Reproduction. 33, 6, p. 998-1008 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Behandling og udredning af mandlig infertilitet og hypogonadisme

    Carlsen, E., Jørgensen, N., Juul, Anders & Skakkebæk, Niels Erik, 2005, In: Maanedsskrift for Praktisk Laegegerning. 83, p. 1239-49 10 p.

    Research output: Contribution to journal › Review › Research

  45. Published

    Bisphenol A Diglycidyl Ether (BADGE) and Bisphenol Analogs, but Not Bisphenol A (BPA), Activate the CatSper Ca2+ Channel in Human Sperm

    Rehfeld, Anders Aagaard, Andersson, A. M. & Skakkebæk, Niels Erik, 2020, In: Frontiers in Endocrinology. 11, 11 p., 324.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Bisphenol A Diglycidyl Ether (BADGE) and Progesterone Do Not Induce Ca2+ Signals in Boar Sperm Cells

    Rehfeld, Anders Aagaard, Mendoza, N., Ausejo, R. & Skakkebæk, Niels Erik, 2020, In: Frontiers in Physiology. 11, p. 785

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Bisphenol A and other phenols in urine from Danish children and adolescents analyzed by isotope diluted TurboFlow-LC-MS/MS

    Frederiksen, H., Aksglaede, L., Sorensen, K., Nielsen, O., Main, Katharina Maria, Skakkebæk, Niels Erik, Juul, Anders & Andersson, A., 2013, In: International Journal of Hygiene and Environmental Health.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Bone mineral density is preserved in men with idiopathic infertility

    Antonio, L., Priskorn, L., Nordkap, L., Bang, A. K., Jensen, T. K., Skakkebæk, Niels Erik, Petersen, Jørgen Holm, Vanderschueren, D. & Jørgensen, N., 2020, In: Andrology. 8, 2, p. 315-322 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis

    Trasande, L., Zoeller, R. T., Hass, U., Kortenkamp, A., Grandjean, P., Myers, J. P., DiGangi, J., Hunt, P. M., Rudel, R., Sathyanarayana, S., Bellanger, M., Hauser, R., Legler, J., Skakkebæk, Niels Erik & Heindel, J. J., Jul 2016, In: Andrology. 4, 4, p. 565-572 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours

    Sonne, Si Brask, Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, Kristian, Daugaard, G., Skakkebæk, Niels Erik, Leffers, H., Rajpert-De Meyts, E., Sonne, S. B., Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, K., Daugaard, G., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 114, 7-8, p. 549-58 10 p.

    Research output: Contribution to journal › Journal article › Research

  51. Published

    Caffeine intake and semen quality in a population of 2,554 young Danish men

    Jensen, T. K., Swan, S. H., Skakkebæk, Niels Erik, Rasmussen, S. & Jørgensen, N., 15 Apr 2010, In: American Journal of Epidemiology. 171, 8, p. 883-91 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Carcinoma in situ in the testis

    Rørth, M., Rajpert-De Meyts, E., Andersson, L., Dieckmann, Peter, Fosså, S. D., Grigor, K. M., Hendry, W. F., Herr, H. W., Looijenga, L. H., Oosterhuis, J. W. & Skakkebæk, Niels Erik, 2000, In: Scandinavian Journal of Urology and Nephrology, Supplementum. 205, p. 166-86 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Carcinoma in situ of contralateral testis in patients with testicular germ cell cancer: study of 27 cases in 500 patients

    von der Maase, H., Rørth, M., Walbom-Jørgensen, S., Sørensen, B. L., Christophersen, I. S., Hald, Tine Marianne, Jacobsen, G. K., Berthelsen, Jens & Skakkebæk, Niels Erik, 1986, In: British medical journal (Clinical research ed.). 293, 6559, p. 1398-401 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells

    Almstrup, Kristian, Nielsen, J. E., Mlynarska, O., Jansen, M. T., Jørgensen, A., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 12 Oct 2010, In: British Journal of Cancer. 103, 8, p. 1269-76 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Cardiovascular risk factors in men: The role of gonadal steroids and sex hormone-binding globulin

    Gyllenborg, J., Rasmussen, S. L., Borch-Johnsen, K., Heitmann, B. L., Skakkebæk, Niels Erik & Juul, Anders, 2001, In: Metabolism. 50, 8, p. 882-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Central Precocious Puberty in two Boys with Prader-Willi Syndrome on Growth Hormone Treatment

    Monai, E., Johansen, A., Clasen-Linde, E., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Main, Katharina Maria, Jørgensen, A. & Jensen, R. B., 2019, In: AACE Clinical Case Reports. 5, 6, p. e352-e356

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Changes in Anti-Mullerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years

    Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, Annette Korsholm, Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, Allan René, Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-5364 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Changes in Anti-Müllerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years

    Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, A. K. M., Hagen, C., Jensen, R., Petersen, Jørgen Holm, Linneberg, Allan René, Andersson, A., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-5364 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Changes in anti-Müllerian hormone (AMH) throughout the life span: a population-based study of 1027 healthy males from birth (cord blood) to the age of 69 years

    Aksglaede, L., Sørensen, K., Boas, M., Mouritsen, A., Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, Allan René, Andersson, A., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-64 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Changes in semen and the testis

    Skakkebæk, Niels Erik & Keiding, N., 19 Nov 1994, In: BMJ. 309, 6965, p. 1316-1317 2 p.

    Research output: Contribution to journal › Editorial › Research

  61. Published

    Changes in serum concentrations of growth hormone, insulin, insulin-like growth factor and insulin-like growth factor-binding proteins 1 and 3 and urinary growth hormone excretion during the menstrual cycle

    Juul, Anders, Scheike, T. H., Pedersen, Anette Tønnes, Main, Katharina Maria, Andersson, A. M., Pedersen, L. M. & Skakkebæk, Niels Erik, 1997, In: Human Reproduction. 12, 10, p. 2123-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation

    Rajpert-De Meyts, E., Poll, S. N., Goukasian, I., Jeanneau, C., Herlihy, A. S., Bennett, Eric Paul, Skakkebæk, Niels Erik, Clausen, Henrik, Giwercman, A. & Mandel, Ulla, 2007, In: Virchows Archiv. 451, 4, p. 805-14 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Changes in urinary excretion of phthalates, phthalate substitutes, bisphenols and other polychlorinated and phenolic substances in young Danish men: 2009–2017

    Frederiksen, H., Nielsen, O., Koch, H. M., Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Andersson, A. M., Jan 2020, In: International Journal of Hygiene and Environmental Health. 223, 1, p. 93-105

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Characterisation and localisation of the endocannabinoid system components in the adult human testis

    Nielsen, J. E., Rolland, A. D., Rajpert-De Meyts, E., Janfelt, Christian, Jørgensen, A., Winge, S. B., Kristensen, D. M., Juul, Anders, Chalmel, F., Jégou, B. & Skakkebæk, Niels Erik, 2019, In: Scientific Reports. 9, 1, 14 p., 12866.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Chemical UV Filters Mimic the Effect of Progesterone on Ca(2+) Signaling in Human Sperm Cells

    Rehfeld, Anders Aagaard, Dissing, Steen & Skakkebæk, Niels Erik, Nov 2016, In: Endocrinology. 157, 11, p. 4297-4308 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth

    Boas, M., Frederiksen, H., Feldt-Rasmussen, Ulla, Skakkebæk, Niels Erik, Hegedüs, L., Hilsted, L. M., Juul, Anders & Main, Katharina Maria, 1 Oct 2010, In: Environmental Health Perspectives. 118, 10, p. 1458-64 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations

    Kirk, I. K., Weinhold, N., Belling, K., Skakkebæk, Niels Erik, Jensen, T. S., Leffers, H., Juul, Anders & Brunak, Søren, 22 Mar 2017, In: Cell Systems. 4, 3, 11 p., 357-364.e3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience

    Aksglaede, L., Skakkebæk, Niels Erik, Almstrup, Kristian & Juul, Anders, 1 Jun 2011, In: Acta Paediatrica. 100, 6, p. 793-806 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Clinical, genetic, biochemical, and testicular biopsy findings among 1,213 men evaluated for infertility

    Olesen, I. A., Andersson, A., Aksglaede, L., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Jørgensen, N. & Juul, Anders, Jan 2017, In: Fertility and Sterility. 107, 1, p. 74-82.e7

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Commentary: sperm counts, data responsibility, and good scientific practice

    Skakkebæk, Niels Erik, Andersson, A., Juul, Anders, Jensen, T. K., Almstrup, Kristian, Toppari, J. & Jørgensen, N., 1 Sep 2011, In: Epidemiology. 22, 5, p. 620-1 2 p.

    Research output: Contribution to journal › Letter › Research

  71. Published

    Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents

    Lottrup, G., Belling, K., Leffers, H., Nielsen, J. E., Dalgaard, M. D., Juul, Anders, Skakkebæk, Niels Erik, Brunak, Søren & Meyts, E. R., 1 May 2017, In: Molecular Human Reproduction. 23, 5, p. 339-354 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Compensated reduction in Leydig cell function is associated with lower semen quality variables: A study of 8182 European young men

    Jørgensen, N., Joensen, Ulla Nordström, Toppari, J., Punab, M., Erenpreiss, J., Zilaitiene, B., Paasch, U., Salzbrunn, A., Fernandez, M. F., Virtanen, H. E., Matulevicius, V., Olea, N., Jensen, T. K., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Andersson, A. M., 1 May 2016, In: Human Reproduction. 31, 5, p. 947-957 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland

    Shen, H., Main, K. M., Andersson, A. M., Damgaard, I. N., Virtanen, H. E., Toppari, J., Schramm, K. W. & Skakkebæk, Niels Erik, 2008, In: Human Reproduction. 23, 1, p. 201-210 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Consequences of stopping Growth hormone (GH) therapy in young GH-deficient patients with childhood-onset disease

    Juul, Anders, Vahl, N., Jørgensen, J., Christiansen, J. & Skakkebæk, Niels Erik, 1998, In: Growth Hormone & I G F Research. p. 15-19 4 p.

    Research output: Contribution to journal › Review › Research

  75. Published

    Continuation of growth hormone (GH) therapy in GH-deficient patients during transition from childhood to adulthood: impact on insulin sensitivity and substrate metabolism

    Nørrelund, H., Vahl, N., Juul, Anders, Møller, N., Alberti, K. G., Skakkebæk, Niels Erik, Christiansen, J. S. & Jørgensen, J. O., 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 5, p. 1912-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function

    Jørgensen, J., Nørrelund, H., Vahl, N., Juul, Anders, Skakkebæk, Niels Erik & Christiansen, J. S., 2002, In: Journal of Pediatric Endocrinology and Metabolism. 15 Suppl 5, p. 1355-60 6 p.

    Research output: Contribution to journal › Journal article › Research

  77. Published

    Contralateral biopsy in the management of testicular cancer: what we have learned and what we need to improve

    Rørth, M., Grigor, K. M., Jørgensen, N., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., Jan 2015, In: Andrology. 3, 1, p. 99-101 3 p.

    Research output: Contribution to journal › Editorial › Research

  78. Published

    Cotinine concentrations in maternal serum and amniotic fluid during pregnancy and risk of testicular germ cell cancer in the offspring: A prospective nested case-control study

    Beck, A. L., Uldbjerg, C. S., Lim, Youn-Hee, Coull, B. A., Sørensen, K. M., Utko, M. M., Wilkowski, B., Rantakokko, P., Bengtsson, M., Lindh, C., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Hauser, R., Juul, Anders & Bräuner, E. V., 2023, In: International Journal of Cancer. 154, 1, p. 71-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Country-specific chemical signatures of persistent environmental compounds in breast milk

    Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T., Kiviranta, H., Taboureau, O., Brunak, S., Main, K. M., Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T. & 4 others, Kiviranta, H., Taboureau, O., Brunak, S. & Main, Katharina Maria, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 270-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Country-specific chemical signatures of persistent organic pollutants (POPs) in breast milk of French, Danish and Finnish women

    Antignac, J. P., Main, Katharina Maria, Virtanen, H. E., Boquien, C. Y., Marchand, P., Venisseau, A., Guiffard, I., Bichon, E., Wohlfahrt-Veje, C., Legrand, S., Boscher, C., Skakkebæk, Niels Erik, Toppari, J. & Le Bizec, B., Nov 2016, In: Environmental Pollution. 218, p. 728-738 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection

    Toppari, J., Virtanen, H. E., Main, Katharina Maria & Skakkebæk, Niels Erik, 1 Oct 2010, In: Birth Defects Research. Part A: Clinical and Molecular Teratology. 88, 10, p. 910-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Cryptorchidism as part of the testicular dysgenesis syndrome: the environmental connection

    Main, Katharina Maria, Skakkebæk, Niels Erik & Toppari, J., 2009, In: Endocrine Development. 14, p. 167-73 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Cryptorchidism, hypospadias, testicular tumours and testicular dysgenesis syndrome

    Rajpert-De Meyts, E., Main, Katharina Maria, Toppari, J. & Skakkebæk, Niels Erik, 2010, Endocrinology.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  84. Published

    Den prognostiske værdi af insulinlignende vækstfaktor i (IGF-I) og bindingsproteinet IGFBP-3 ved alkoholistisk leversygdom

    Møller, S., Becker, U., Juul, Anders, Skakkebæk, Niels Erik, Christensen, E. & EMALD-gruppen, E., 1997, In: Ugeskrift for Laeger. 159, 30, p. 4636-4640 4 p.

    Research output: Contribution to journal › Journal article › Research

  85. Published

    Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry

    Li, Z., Giesert, F., Vogt-Weisenhorn, D., Main, Katharina Maria, Skakkebæk, Niels Erik, Kiviranta, H., Toppari, J., Feldt-Rasmussen, Ulla, Shen, H., Schramm, K. & De Angelis, M., 2018, In: Journal of Chromatography A. 1534, p. 85-92

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Development and descent of the testis in relation to cryptorchidism

    Virtanen, H. E., Cortes, Dina, Rajpert-De Meyts, E., Ritzén, E. M., Nordenskjöld, A., Skakkebæk, Niels Erik & Toppari, J., 1 May 2007, In: Acta Paediatrica. 96, 5, p. 622-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Development: disorders of sex development-the tip of the iceberg?

    Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 1 Jan 2011, In: Nature Reviews Endocrinology. 7, 9, p. 504-5 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Developmental origins of testicular germ cell tumours (TGCT)

    Meyts, E. R., Jørgensen, A., Jørgensen, N., Almstrup, Kristian & Skakkebæk, Niels Erik, Sep 2019, In: European Urology Supplements. 18, 4, p. 11

    Research output: Contribution to journal › Conference abstract in journal › Research

  89. Published

    Diagnosis of GH deficiency and use of GH in children with growth disorders. A report from the Drugs and Therapeutics Committee of European Society for paediatric Endocrinology

    Juul, Anders, Bernasconi, S., Chatelain, P., Hindsmarsh, P., Hochberg, Z., Hokke-Koelega, A., De Muinck Keizer-Schrama, S., Kiess, W., Oberfield, S., Strasburger, C., Volta, C., Westphal, O. & Skakkebæk, Niels Erik, 1999, In: Hormone Research. 51, p. 284-299 15 p.

    Research output: Contribution to journal › Review › Research

  90. Diagnostic markers for germ cell neoplasms: From placental-like alkaline phosphatase to micro-RNAs

    Meyts, E. R. D., Nielsen, J. E., Skakkebæk, Niels Erik & Almstrup, Kristian, 8 Oct 2015, In: Folia Histochemica et Cytobiologica. 53, 3, p. 177-188 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Diminished concentrations of insulin-like growth factor I in cystic fibrosis

    Laursen, E., Juul, Anders, Lanng, S., Høiby, N., Koch, C., Müller, J. & Skakkebæk, Niels Erik, 1995, In: Archives of Disease in Childhood. Education and Practice Edition. 72, 6, p. 494-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Direct action of endocrine disrupting chemicals on human sperm

    Schiffer, C., Müller, A., Egeberg, D. L., Alvarez, L., Brenker, C., Rehfeld, Anders Aagaard, Frederiksen, H., Wäschle, B., Kaupp, U. B., Balbach, M., Wachten, D., Skakkebæk, Niels Erik, Almstrup, Kristian & Strünker, T., Jul 2014, In: E M B O Reports. 15, 7, p. 758-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Disorders of sexual differentiation-the tip of the iceberg?

    Juul, Anders, Main, Katharina Maria & Skakkebæk, Niels Erik, 2011, In: Nature Reviews Endocrinology. 7, p. 504-5 1 p.

    Research output: Contribution to journal › Letter › Research

  94. Published

    Distinguishing between hidden testes and anorchia: The role of endocrine evaluation in infancy and childhood

    Jespersen, K., Ljubicic, M. L., Johannsen, T. H., Christiansen, P., Skakkebæk, Niels Erik & Juul, Anders, 2020, In: European Journal of Endocrinology. 183, 1, p. 107-117 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Do environmental estrogens contribute to the decline in male reproductive health?

    Jensen, T. K., Toppari, J., Keiding, N. & Skakkebæk, Niels Erik, Dec 1995, In: Clinical Chemistry. 41, 12, p. 1896-1901 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Do environmental factors play a role in the aetiology of carcinoma in situ testis and the testicular dysgenesis syndrome?

    Sonne, Si Brask, Hoei-Hansen, C. E., Fisher, J. S., Leffers, H., Rajpert-de Meyts, E. & Skakkebæk, Niels Erik, 2004, In: Verhandlungen der Deutschen Gesellschaft fur Pathologie. 88, p. 144-51 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Do perfluoroalkyl compounds impair human semen quality?

    Joensen, Ulla Nordström, Bossi, R., Leffers, H., Jensen, A. A., Skakkebæk, Niels Erik & Jørgensen, N., 2009, In: Environmental Health Perspectives. 117, 6, p. 923-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Does breast feeding influence liver biochemistry?

    Jørgensen, M. H., Ott, P., Juul, Anders, Skakkebæk, Niels Erik & Michaelsen, K. F., 2003, In: Journal of Pediatric Gastroenterology and Nutrition. 37, 5, p. 559-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

    Rehfeld, Anders Aagaard, Egeberg, D., Almstrup, Kristian, Petersen, Jørgen Holm, Dissing, Steen & Skakkebæk, Niels Erik, 2018, In: Endocrine Connections. 7, 1, p. 16-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Early Life Events Predict Adult Testicular Function: Data Derived From the Western Australian (Raine) Birth Cohort

    Hart, R. J., Doherty, D. A., Keelan, J. A., McLachlan, R., Skakkebæk, Niels Erik, Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In: The Journal of clinical endocrinology and metabolism. 101, 9, p. 3333-3344 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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