Niels Erik Skakkebæk
Affiliate Professor
- 2011
- Published
Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat
Kristensen, D. M., Hass, U., Lesné, L., Lottrup, G., Jacobsen, P. R., Desdoits-Lethimonier, C., Boberg, J., Petersen, Jørgen Holm, Toppari, J., Jensen, T. K., Brunak, Søren, Skakkebæk, Niels Erik, Nellemann, C., Main, Katharina Maria, Jégou, B. & Leffers, H., 2011, In: Human Reproduction. 26, 1, p. 235-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum concentrations of Anti-Müllerian Hormone (AMH) in 95 patients with Klinefelter syndrome with or without cryptorchidism
Aksglaede, L., Christiansen, P., Sørensen, K., Boas, M., Linneberg, Allan René, Main, Katharina Maria, Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 2011, In: Acta Paediatrica. 100, 6, p. 839-845 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex chromosome aneuploidy and anthropometry
Aksglæde, L., Skakkebæk, Niels Erik & Juul, Anders, 2011, Handbook of Anthropometry: Physical measures of human form in health and disease. SpringerResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- 2010
- Published
OCT4 and downstream factors are expressed in human somatic urogenital epithelia and in culture of epididymal spheres
Kristensen, D. M., Nielsen, J. E., Kalisz, M., Dalgaard, M. D., Audouze, K., Larsen, M. E., Jacobsen, G. K., Horn, T., Brunak, S., Skakkebaek, N. E., Leffers, H., Kristensen, D. M., Nielsen, J. E., Kalisz, M., Dalgaard, M. D., Audouze, K. M. L., Larsen, M. E., Jacobsen, G. K., Horn, T., Brunak, S. & 2 others, , 1 Nov 2010, In: Molecular Human Reproduction. 16, 11, p. 835-45 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum inhibin-b in fertile men is strongly correlated with low but not high sperm counts: a coordinated study of 1,797 European and US men
Jørgensen, N., Liu, F., Andersson, A., Vierula, M., Irvine, D. S., Auger, J., Brazil, C. K., Drobnis, E. Z., Jensen, T. K., Jouannet, P., Overstreet, J. W., Redmon, J. B., Sparks, A., Toppari, J., Wang, C., Skakkebæk, Niels Erik & Swan, S. H., 1 Nov 2010, In: Fertility and Sterility. 94, 6, p. 2128-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells
Almstrup, Kristian, Nielsen, J. E., Mlynarska, O., Jansen, M. T., Jørgensen, A., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 12 Oct 2010, In: British Journal of Cancer. 103, 8, p. 1269-76 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth
Boas, M., Frederiksen, H., Feldt-Rasmussen, Ulla, Skakkebæk, Niels Erik, Hegedüs, L., Hilsted, L. M., Juul, Anders & Main, Katharina Maria, 1 Oct 2010, In: Environmental Health Perspectives. 118, 10, p. 1458-64 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection
Toppari, J., Virtanen, H. E., Main, Katharina Maria & Skakkebæk, Niels Erik, 1 Oct 2010, In: Birth Defects Research. Part A: Clinical and Molecular Teratology. 88, 10, p. 910-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular non-seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Schmoll, H., Jordan, K., Huddart, R., Pes, M. P. L., Horwich, A., Fizazi, K., Kataja, V., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, ESMO Guidelines Working Group, E. G. W. G. & von der Maase, H. R. R., 1 May 2010, In: Annals of Oncology. 21 Suppl 5, p. v147-54Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Schmoll, H., Jordan, K., Huddart, R., Pes, M. P. L., Horwich, A., Fizazi, K., Kataja, V., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, ESMO Guidelines Working Group, E. G. W. G. & von der Maase, H. R. R., 1 May 2010, In: Annals of Oncology. 21 Suppl 5, p. v140-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract
Jensen, Martin Blomberg, Nielsen, J. E., Jørgensen, A., Rajpert-De Meyts, E., Kristensen, D. M., Jørgensen, N., Skakkebæk, Niels Erik, Juul, Anders & Leffers, H., 1 May 2010, In: Human Reproduction. 25, 5, p. 1303-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Caffeine intake and semen quality in a population of 2,554 young Danish men
Jensen, T. K., Swan, S. H., Skakkebæk, Niels Erik, Rasmussen, S. & Jørgensen, N., 15 Apr 2010, In: American Journal of Epidemiology. 171, 8, p. 883-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Country-specific chemical signatures of persistent environmental compounds in breast milk
Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T., Kiviranta, H., Taboureau, O., Brunak, S., Main, K. M., Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T. & 4 others, , 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 270-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genital anomalies in boys and the environment
Main, Katharina Maria, Skakkebæk, Niels Erik, Virtanen, H. E. & Toppari, J., 1 Apr 2010, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 24, 2, p. 279-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypothesis: exposure to endocrine-disrupting chemicals may interfere with timing of puberty
Mouritsen, Annette Korsholm, Aksglaede, L., Sørensen, K., Mogensen, S. S., Leffers, H., Main, Katharina Maria, Frederiksen, H., Andersson, A., Skakkebæk, Niels Erik & Juul, Anders, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 346-59 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proceedings of the 5th Copenhagen Workshop on endocrine disrupters: ubiquitous endocrine disrupters and possible human health effects. Preface
Andersson, A., Bay, K., Grigor, K. M., Toppari, J. & Skakkebæk, Niels Erik, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 251 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular dysgenesis syndrome comprises some but not all cases of hypospadias and impaired spermatogenesis
Jørgensen, N., Rajpert-De Meyts, E., Main, Katharina Maria & Skakkebæk, Niels Erik, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 298-303 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular germ cell cancer incidence in an immigration perspective, Denmark, 1978 to 2003
Schmiedel, S., Schüz, J., Skakkebæk, Niels Erik & Johansen, C., 1 Apr 2010, In: Journal of Urology. 183, 4, p. 1378-82 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Semen quality, reproductive hormones and fertility of men operated for hypospadias
Asklund, C., Jensen, T. K., Main, Katharina Maria, Sobotka, T., Skakkebæk, Niels Erik & Jørgensen, N., 1 Feb 2010, In: International Journal of Andrology. 33, 1, p. 80-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of circulating sex steroid levels in prepubertal and pubertal boys and girls by a novel ultrasensitive gas chromatography-tandem mass spectrometry method
Courant, F., Aksglæde, L., Antignac, J., Monteau, F., Sørensen, K., Andersson, A., Skakkebæk, Niels Erik, Juul, Anders & Bizec, B. L., 1 Jan 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 82-92 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal reference ranges for semen quality and their relations to fecundity
Skakkebæk, Niels Erik, 1 Jan 2010, In: Asian Journal of Andrology. 12, 1, p. 95-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Anti-Mullerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years
Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, Annette Korsholm, Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, Allan René, Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-5364 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Anti-Müllerian Hormone (AMH) throughout the Life Span: A Population-Based Study of 1027 Healthy Males from Birth (Cord Blood) to the Age of 69 Years
Aksglæde, L., Sørensen, K., Boas, M., Mouritsen, A. K. M., Hagen, C., Jensen, R., Petersen, Jørgen Holm, Linneberg, Allan René, Andersson, A., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-5364 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in anti-Müllerian hormone (AMH) throughout the life span: a population-based study of 1027 healthy males from birth (cord blood) to the age of 69 years
Aksglaede, L., Sørensen, K., Boas, M., Mouritsen, A., Hagen, C. P., Jensen, R. B., Petersen, J. H., Linneberg, Allan René, Andersson, A., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. 5357-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryptorchidism, hypospadias, testicular tumours and testicular dysgenesis syndrome
Rajpert-De Meyts, E., Main, Katharina Maria, Toppari, J. & Skakkebæk, Niels Erik, 2010, Endocrinology.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2009
- Published
Analysis of gene expression profiles of microdissected cell populations indicates that testicular carcinoma in situ is an arrested gonocyte
Sonne, Si Brask, Almstrup, Kristian, Dalgaard, M., Juncker, A. S., Edsgard, D., Ruban, L., Harrison, N. J., Schwager, C., Abdollahi, A., Huber, P. E., Brunak, Søren, Gjerdrum, L. M., Moore, H. D., Andrews, P. W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jun 2009, In: Current Cancer Research. 69, 12, p. 5241-50 10 p.Research output: Contribution to journal › Journal article › Research
- Published
Re: Niels J. van Casteren, Hans Stoop, Gert R. Dohle, Ronald de Wit, J. Wolter Oosterhuis, Leendert H.J. Looijenga. Noninvasive Detection of Testicular Carcinoma In Situ in Semen Using OCT3/4. Eur Urol 2008;54:153-60
Høi-Hansen, Christina Engel, Almstrup, Kristian, Skakkebæk, Niels Erik & Rajpert-De Meyts, E., Apr 2009, In: European Urology. 55, 4, p. e67-e68Research output: Contribution to journal › Letter › Research › peer-review
- Published
Re: The true incidence of cryptorchidism in Denmark: D. Cortes, E. M. Kjellberg, M. Breddam and J. Thorup, J Urol 2008; 179: 314-318
Thorup, Jørgen Mogens, Cortes, Dina, Main, Katharina Maria, Skakkebæk, Niels Erik & Toppari, J., Feb 2009, In: The Journal of Urology. 181, 2, p. 922-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early puberty in internationally adopted girls: hormonal and clinical markers of puberty in 276 girls examined biannually over two years
Teilmann, Grete Katrine, Petersen, Jørgen Holm, Gormsen, M., Damgaard, K., Skakkebæk, Niels Erik, Jensen, T. K., Teilmann, Grete Katrine, Petersen, J. H., Gormsen, M., Damgaard, K., Skakkebæk, Niels Erik & Jensen, T. K., 1 Jan 2009, In: Hormone Research. 72, 4, p. 236-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression profiles of mouse spermatogenesis during recovery from irradiation
Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H., Almstrup, K., Shah, F. J., Tanaka, M., Nielsen, J. E., Iwamoto, T., Kobayashi, S., Skakkebæk, Niels Erik, Leffers, H. & Almstrup, Kristian, 1 Jan 2009, In: Reproductive Biology and Endocrinology. 7, p. 130Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquired cryptorchidism is frequent in infancy and childhood
Wohlfahrt-Veje, C., Boisen, K. A., Boas, M., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Chellakooty, M., Suomi, A., Toppari, J., Skakkebæk, Niels Erik & Main, Katharina Maria, 2009, In: International Journal of Andrology. 32, 4, p. 423-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryptorchidism as part of the testicular dysgenesis syndrome: the environmental connection
Main, Katharina Maria, Skakkebæk, Niels Erik & Toppari, J., 2009, In: Endocrine Development. 14, p. 167-73 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do perfluoroalkyl compounds impair human semen quality?
Joensen, Ulla Nordström, Bossi, R., Leffers, H., Jensen, A. A., Skakkebæk, Niels Erik & Jørgensen, N., 2009, In: Environmental Health Perspectives. 117, 6, p. 923-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is there a problem with male reproduction?
Joensen, Ulla Nordström, Skakkebæk, Niels Erik & Jørgensen, N., 2009, In: Nature Clinical Practice Endocrinology & Metabolism. 5, 3, p. 144-5 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent decline in age at breast development: the Copenhagen Puberty Study
Aksglaede, L., Sørensen, K., Petersen, J. H., Skakkebæk, Niels Erik & Juul, Anders, 2009, In: Pediatrics. 123, 5, p. e932-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent decline in age at breast development: the Copenhagen Puberty Study
Aksglaede, L., Sørensen, K., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Juul, Anders, 2009, In: Pediatrics Electronic Pages. 123, 5, p. e932-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular dysgenesis syndrome: foetal origin of adult reproductive problems
Wohlfahrt-Veje, C., Main, Katharina Maria & Skakkebæk, Niels Erik, 2009, In: Clinical Endocrinology. 71, 4, p. 459-65 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Insulin-like factor 3 levels in second-trimester amniotic fluid
Bay, K., Cohen, A. S., Jørgensen, Finn Stener, Jørgensen, C., Lind, A. M., Skakkebæk, Niels Erik & Andersson, A., 1 Oct 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 4048-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary excretion of phthalates and paraben after repeated whole-body topical application in humans
Janjua, N. R., Frederiksen, H., Skakkebæk, Niels Erik, Wulf, H. C. & Andersson, A., 1 Apr 2008, In: International Journal of Andrology. 31, 2, p. 118-30 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abnormal sex chromosome constitution and longitudinal growth: serum levels of insulin-like growth factor (IGF)-I, IGF binding protein-3, luteinizing hormone, and testosterone in 109 males with 47,XXY, 47,XYY, or sex-determining region of the Y chromosome (SRY)-positive 46,XX karyotypes
Aksglaede, L., Skakkebæk, Niels Erik & Juul, Anders, 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 1, p. 169-176 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adverse trends in male reproductive health: we may have reached a crucial 'tipping point'
Andersson, A., Jørgensen, N., Main, Katharina Maria, Toppari, J., Rajpert-De Meyts, E., Leffers, H., Juul, Anders, Jensen, T. K. & Skakkebæk, Niels Erik, 2008, In: International Journal of Andrology. 31, 2, p. 74-80 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
Jensen, Martin Blomberg, Leffers, H., Petersen, Jørgen Holm, Daugaard, G., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 2008, In: Annals of Oncology. 19, 11, p. 1910-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland
Shen, H., Main, K. M., Andersson, A. M., Damgaard, I. N., Virtanen, H. E., Toppari, J., Schramm, K. W. & Skakkebæk, Niels Erik, 2008, In: Human Reproduction. 23, 1, p. 201-210 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Environmental factors and puberty timing: expert panel research needs
Louis, G. M. B., Jr, L. E. G., Marcus, M., Ojeda, S. R., Pescovitz, O. H., Witchel, S. F., Sippell, W., Abbott, D. H., Soto, A., Tyl, R. W., Bourguignon, J. P., Swan, S. H., Golub, M. S., Wabitsch, M., Toppari, J., Euling, S. Y. & Skakkebæk, Niels Erik, 2008, In: Pediatrics. 121 Suppl 3, p. S192-S207Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing
Crain, D. A., Janssen, S. J., Edwards, T. M., Heindel, J., Ho, S., Hunt, P., Iguchi, T., Juul, Anders, McLachlan, J. A., Schwartz, J., Skakkebæk, Niels Erik, Soto, A. M., Swan, S., Walker, C., Woodruff, T. K., Woodruff, T. J., Giudice, L. C. & Guillette, L. J., 2008, In: Fertility and Sterility. 90, 4, p. 911-40 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low semen volume in 47 adolescents and adults with 47,XXY Klinefelter or 46,XX male syndrome
Aksglaede, L., Jørgensen, N., Skakkebæk, Niels Erik & Juul, Anders, 2008, In: International Journal of Andrology. 32, 4, p. 376-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mere Testikelkræft og dårlig sædkvalitet
Skakkebæk, Niels Erik, 2008, In: Tidsskrift for Den norske lægeforening. 128, p. 554-554Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Origin of pluripotent germ cell tumours: the role of microenvironment during embryonic development
Kristensen, D. M., Sonne, Si Brask, Ottesen, A. M., Perrett, R. M., Nielsen, J. E., Almstrup, Kristian, Skakkebæk, Niels Erik, Leffers, H. & Meyts, E. R., 2008, In: Molecular and Cellular Endocrinology. 288, 1-2, p. 111-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of environmental factors in the timing of puberty
Euling, S. Y., Selevan, S. G., Pescovitz, O. H. & Skakkebæk, Niels Erik, 2008, In: Pediatrics. 121 Suppl 3, p. S167-S171Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Semen quality in sub-fertile range for a significant proportion of young men from the general German population: a co-ordinated, controlled study of 791 men from Hamburg and Leipzig
Paasch, U., Salzbrunn, A., Glander, H. J., Plambeck, K., Salzbrunn, H., Grunewald, S., Stucke, J., Vierula, M., Jorgensen, N. & Skakkebæk, Niels Erik, 2008, In: International Journal of Andrology. 31, 2, p. 93-102 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sons conceived by assisted reproduction techniques inherit deletions in the azoospermia factor (AZF) region of the Y chromosome and the DAZ gene copy number
Mau Kai, C., Juul, Anders, McElreavey, K., Ottesen, A. M., Garn, I. D., Main, Katharina Maria, Loft, A., Jørgensen, N., Skakkebæk, Niels Erik, Andersen, A. N. & Rajpert-De Meyts, E., 2008, In: Human Reproduction. 23, 7, p. 1669-1678 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular dysgenesis syndrome and the origin of carcinoma in situ testis
Sonne, Si Brask, Kristensen, D. M., Novotny, G. W., Olesen, I. A., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 2008, In: International Journal of Andrology. 31, 2, p. 275-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects
Sharpe, R. M. & Skakkebæk, Niels Erik, 2008, In: Fertility and Sterility. 89, 2 Suppl, p. e33-e38Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The faroes statement: human health effects of developmental exposure to chemicals in our environment
Grandjean, P., Bellinger, D., Bergman, A., Cordier, S., vey-Smith, G., Eskenazi, B., Gee, D., Gray, K., Hanson, M., den, H. P. V., Heindel, J. J., Heinzow, B., Hertz-Picciotto, I., Hu, H., Huang, T. T., Jensen, T. K., Landrigan, P. J., McMillen, I. C., Murata, K., Ritz, B. & 4 others, , 2008, In: Basic & Clinical Pharmacology & Toxicology. 102, 2, p. 73-75 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Age at voice break in Danish boys: effects of pre-pubertal body mass index and secular trend
Juul, Anders, Magnusdottir, S., Scheike, T., Prytz, S. & Skakkebæk, Niels Erik, 1 Dec 2007, In: International Journal of Andrology. 30, 6, p. 537-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys
Andersson, A., Jensen, T. K., Juul, Anders, Petersen, Jørgen Holm, Jørgensen, T. & Skakkebæk, Niels Erik, 1 Dec 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4696-705 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Self-rated health and semen quality among 3,457 young Danish men
Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Kristensen, T. S., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Nov 2007, In: Fertility and Sterility. 88, 5, p. 1366-73 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism
Bay, K., Virtanen, H. E., Hartung, S., Ivell, R., Main, Katharina Maria, Skakkebæk, Niels Erik, Andersson, A., Toppari, J. & Nordic Cryptorchidism Study Group, N. C. S. G., 1 Oct 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 4020-7 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Testicular dysgenesis syndrome and carcinoma in situ of the testes
Joensen, Ulla Nordström, Jorgensen, N. & Skakkebæk, Niels Erik, Aug 2007, In: Nature Clinical Practice Urology. 4, 8, p. 402-403 2 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Metabolism of phthalates in humans
Frederiksen, H., Skakkebæk, Niels Erik & Andersson, A., 1 Jul 2007, In: Molecular Nutrition & Food Research. 51, 7, p. 899-911 13 p.Research output: Contribution to journal › Journal article › Research
- Published
Development and descent of the testis in relation to cryptorchidism
Virtanen, H. E., Cortes, Dina, Rajpert-De Meyts, E., Ritzén, E. M., Nordenskjöld, A., Skakkebæk, Niels Erik & Toppari, J., 1 May 2007, In: Acta Paediatrica. 96, 5, p. 622-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general population
Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Mar 2007, In: American Journal of Epidemiology. 165, 5, p. 583-90 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts
Aksglaede, L., Andersson, A., Jørgensen, N., Jensen, T. K., Carlsen, E., McLachlan, R. I., Skakkebæk, Niels Erik, Petersen, Jørgen Holm & Juul, Anders, 1 Feb 2007, In: Clinical Endocrinology. 66, 2, p. 276-81 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Origin of testicular germ cell neoplasia: The role of sex chromosomes
Rajpert-De Meyts, E., Ottesen, A. M., Høi-Hansen, Christina Engel, Sonne, Si Brask, Leffers, H. & Skakkebæk, Niels Erik, 1 Jan 2007, The Y Chromosome and Male Germ Cell Biology in Health and Diseases. World Scientific Publishing Co., p. 289-308 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Analysis of gene expression in normal and neoplastic human testis: new roles of RNA
Novotny, G. W., Nielsen, J. E., Sonne, Si Brask, Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Leffers, H. & Sonne, Si Brask, 2007, In: International Journal of Andrology. 30, 4, p. 316-327Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation
Rajpert-De Meyts, E., Poll, S. N., Goukasian, I., Jeanneau, C., Herlihy, A. S., Bennett, Eric Paul, Skakkebæk, Niels Erik, Clausen, Henrik, Giwercman, A. & Mandel, Ulla, 2007, In: Virchows Archiv. 451, 4, p. 805-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Environment, testicular dysgenesis and carcinoma in situ testis
Olesen, I. A., Sonne, Si Brask, Hoei-Hansen, C. E., Rajpert-DeMeyts, E. & Skakkebæk, Niels Erik, 2007, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 21, 3, p. 462-78 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part II
Krege, S., Beyer, J., Souchon, R., Albers, P., Albrecht, W., Algaba, F., Bamberg, M., Bodrogi, I., Bokemeyer, C., Cavallin-Ståhl, E., Classen, J., Clemm, C., Cohn-Cedermark, G., Culine, S., Daugaard, G., De Mulder, P. H. M., De Santis, M., de Wit, M., de Wit, R., Derigs, H. G. & 63 others, , 2007, In: European Urology. 53, 3, p. 497-513 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I
Krege, S., Beyer, J., Souchon, R., Albers, P., Albrecht, W., Algaba, F., Bamberg, M., Bodrogi, I., Bokemeyer, C., Cavallin-Ståhl, E., Classen, J., Clemm, C., Cohn-Cedermark, G., Culine, S., Daugaard, G., De Mulder, P. H. M., De Santis, M., de Wit, M., de Wit, R., Derigs, H. G. & 63 others, , 2007, In: European Urology. 53, 3, p. 478-496 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High normal testosterone levels in infants with non-mosaic Klinefelter's syndrome
Aksglaede, L., Petersen, Jørgen Holm, Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2007, In: European Journal of Endocrinology. 157, 3, p. 345-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved gene expression signature of testicular carcinoma in situ
Almstrup, Kristian, Leffers, H., Lothe, R. A., Skakkebæk, Niels Erik, Sonne, Si Brask, Nielsen, J. E., Rajpert-De Meyts, E. & Skotheim, R. I., 2007, In: International Journal of Andrology. 30, 4, p. 292-303Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved fertility in a non-mosaic Klinefelter patient with a mutation in the fibroblast growth factor receptor 3 gene: case report
Juul, Anders, Aksglaede, L., Lund, Allan Meldgaard, Duno, M., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 2007, In: Human Reproduction. 22, 7, p. 1907-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced serum testosterone levels in infant boys conceived by intracytoplasmic sperm injection
Mau Kai, C., Main, Katharina Maria, Andersen, A. N., Loft, A., Skakkebæk, Niels Erik & Juul, Anders, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 7, p. 2598-603 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum sex hormone-binding globulin levels in healthy children and girls with precocious puberty before and during gonadotropin-releasing hormone agonist treatment
Sørensen, K., Andersson, A. M., Skakkebæk, Niels Erik & Juul, Anders, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 3189-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations
Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Jørgensen, N., Main, Katharina Maria, Leffers, H., Andersson, A., Juul, Anders, Jensen, T. K. & Toppari, J., 2007, In: International Journal of Andrology. 30, 4, p. 198-204; discussion 204-5Research output: Contribution to journal › Review › Research
- Published
Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster
Novotny, G. W., Sonne, Si Brask, Nielsen, J. E., Jonstrup, S. P., Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Kjems, J. & Leffers, H., 2007, In: Cell Death and Differentiation. 14, 4, p. 879-82 3 p.Research output: Contribution to journal › Letter › Research
- 2006
- Published
Identification and expression profiling of 10 novel spermatid expressed CYPT genes
Hansen, M. A., Nielsen, J. E., Tanaka, M., Almstrup, Kristian, Skakkebæk, Niels Erik & Leffers, H., May 2006, In: Molecular Reproduction and Development. 73, 5, p. 568-579 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased expression of alpha- and beta-globin mRNAs at the pituitary following exposure to estrogen during the critical period of neonatal sex differentiation in the rat
Leffers, H., Navarro, V. M., Nielsen, J. E., Mayen, A., Pinilla, L., Dalgaard, M., Malagon, M. M., Castaño, J. P., Skakkebæk, Niels Erik, Aguilar, E. & Tena-Sempere, M., 1 Apr 2006, In: Journal of Steroid Biochemistry and Molecular Biology. 99, 1, p. 33-43 11 p.Research output: Contribution to journal › Journal article › Research
- Published
Testicular dysgenesis syndrome: possible role of endocrine disrupters
Bay, K., Asklund, C., Skakkebæk, Niels Erik & Andersson, A., 1 Mar 2006, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 20, 1, p. 77-90 14 p.Research output: Contribution to journal › Journal article › Research
- Published
Is human fecundity declining?
Skakkebæk, Niels Erik, Jørgensen, N., Main, Katharina Maria, Rajpert-De Meyts, E., Leffers, H., Andersson, A., Juul, Anders, Carlsen, E., Mortensen, G. K., Jensen, T. K. & Toppari, J., 1 Feb 2006, In: International Journal of Andrology. 29, 1, p. 2-11 10 p.Research output: Contribution to journal › Journal article › Research
- Published
Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies
Ekbom, P., Damm, Peter, Andersson, A., Skakkebæk, Niels Erik, Feldt-Rasmussen, Ulla & Mathiesen, Elisabeth, 1 Jan 2006, In: Acta Obstetricia et Gynecologica Scandinavica. 85, 2, p. 143-7 5 p.Research output: Contribution to journal › Journal article › Research
- Published
A prospective study of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in 942 healthy infants: associations with birth weight, gender, growth velocity, and breastfeeding
Chellakooty, M., Juul, A., Boisen, K. A., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Main, K. M., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 820-826 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours
Sonne, Si Brask, Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, Kristian, Daugaard, G., Skakkebæk, Niels Erik, Leffers, H., Rajpert-De Meyts, E., Sonne, S. B., Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, K., Daugaard, G., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 114, 7-8, p. 549-58 10 p.Research output: Contribution to journal › Journal article › Research
- Published
From embryonic stem cells to testicular germ cell cancer-- should we be concerned?
Almstrup, Kristian, Sonne, Si Brask, Hoei-Hansen, C. E., Ottesen, A. M., Nielsen, J. E., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: International Journal of Andrology. 29, 1, p. 211-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age
Main, Katharina Maria, Mortensen, G. K., Kaleva, M. M., Boisen, K. A., Damgaard, I. N., Chellakooty, M., Schmidt, I. M., Suomi, A., Virtanen, H. E., Petersen, J. H., Andersson, A., Toppari, J. & Skakkebæk, Niels Erik, 2006, In: Environmental Health Perspectives. 114, 2, p. 270-276 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours
Sonne, Si Brask, Herlihy, A. S., Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, Kristian, Skakkebæk, Niels Erik, Marks, A., Leffers, H. & Rajpert-De Meyts, E., 2006, In: Virchows Archiv. 449, 2, p. 200-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural history of seminiferous tubule degeneration in Klinefelter syndrome
Aksglaede, L., Wikström, A. M., Rajpert-De Meyts, E., Dunkel, L., Skakkebæk, Niels Erik & Juul, Anders, 2006, In: Human Reproduction Update. 12, 1, p. 39-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pubertal development in Danish children: comparison of recent European and US data
Juul, Anders, Teilmann, Grete Katrine, Scheike, T. H., Hertel, N., Holm, Kirsten, Laursen, E., Main, Katharina Maria & Skakkebæk, Niels Erik, 2006, In: International Journal of Andrology. 29, 1, p. 247-55; discussion 286-90Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The sensitivity of the child to sex steroids: possible impact of exogenous estrogens
Aksglaede, L., Juul, Anders, Leffers, H., Skakkebæk, Niels Erik & Andersson, A., 2006, In: Human Reproduction Update. 12, 4, p. 341-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours
Almstrup, Kristian, Høi-Hansen, Christina Engel, Nielsen, J. E., Wirkner, U., Ansorge, W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 23 May 2005, In: British Journal of Cancer. 92, 10, p. 1934-1941 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2γ in semen samples: Case report
Høi-Hansen, Christina Engel, Rajpert-De Meyts, E., Carlsen, E., Almstrup, Kristian, Leffers, H. & Skakkebæk, Niels Erik, Mar 2005, In: Human Reproduction. 20, 3, p. 579-582 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behandling og udredning af mandlig infertilitet og hypogonadisme
Carlsen, E., Jørgensen, N., Juul, Anders & Skakkebæk, Niels Erik, 2005, In: Maanedsskrift for Praktisk Laegegerning. 83, p. 1239-49 10 p.Research output: Contribution to journal › Review › Research
- Published
Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ
Almstrup, Kristian, Ottesen, A. M., Sonne, Si Brask, Hoei-Hansen, C. E., Leffers, H., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 2005, In: Cell and Tissue Research. 322, 1, p. 159-65 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like growth factor I (IGF-I) and IGF-binding protein 3 as diagnostic markers of growth hormone deficiency in infancy
Jensen, R. B., Jeppesen, K. A., Vielwerth, S., Michaelsen, K. F., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Hormone Research. 63, 1, p. 15-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries
Teilmann, Grete Katrine, Pedersen, C., Jensen, T. K., Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Pediatrics. 116, 6, p. 1323-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours
Hoei-Hansen, C. E., Almstrup, Kristian, Nielsen, J. E., Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2005, In: Histopathology. 47, 1, p. 48-56 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling
Almstrup, Kristian, Høi-Hansen, Christina Engel, Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jul 2004, In: Cancer Research. 64, 14, p. 4736-4743 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of cell-type-specific gene expression during mouse spermatogenesis
Almstrup, Kristian, Nielsen, J. E., Hansen, M. A., Tanaka, M., Skakkebæk, Niels Erik & Leffers, H., Jun 2004, In: Biology of Reproduction. 70, 6, p. 1751-1761 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of genes differentially expressed in testes containing carcinoma in situ
Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-DeMeyts, E. & Leffers, H., Jun 2004, In: Molecular Human Reproduction. 10, 6, p. 423-431 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth
Chellakooty, M., Vangsgaard, K., Larsen, T., Scheike, T., Falck-Larsen, J., Legarth, J., Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 1, p. 384-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35319116
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
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Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
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