Development and descent of the testis in relation to cryptorchidism

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Development and descent of the testis in relation to cryptorchidism. / Virtanen, Helena E; Cortes, Dina; Rajpert-De Meyts, Ewa; Ritzén, E Martin; Nordenskjöld, Agneta; Skakkebaek, Niels E; Toppari, Jorma.

In: Acta Paediatrica, Vol. 96, No. 5, 01.05.2007, p. 622-7.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Virtanen, HE, Cortes, D, Rajpert-De Meyts, E, Ritzén, EM, Nordenskjöld, A, Skakkebaek, NE & Toppari, J 2007, 'Development and descent of the testis in relation to cryptorchidism', Acta Paediatrica, vol. 96, no. 5, pp. 622-7. https://doi.org/10.1111/j.1651-2227.2007.00244.x

APA

Virtanen, H. E., Cortes, D., Rajpert-De Meyts, E., Ritzén, E. M., Nordenskjöld, A., Skakkebaek, N. E., & Toppari, J. (2007). Development and descent of the testis in relation to cryptorchidism. Acta Paediatrica, 96(5), 622-7. https://doi.org/10.1111/j.1651-2227.2007.00244.x

Vancouver

Virtanen HE, Cortes D, Rajpert-De Meyts E, Ritzén EM, Nordenskjöld A, Skakkebaek NE et al. Development and descent of the testis in relation to cryptorchidism. Acta Paediatrica. 2007 May 1;96(5):622-7. https://doi.org/10.1111/j.1651-2227.2007.00244.x

Author

Virtanen, Helena E ; Cortes, Dina ; Rajpert-De Meyts, Ewa ; Ritzén, E Martin ; Nordenskjöld, Agneta ; Skakkebaek, Niels E ; Toppari, Jorma. / Development and descent of the testis in relation to cryptorchidism. In: Acta Paediatrica. 2007 ; Vol. 96, No. 5. pp. 622-7.

Bibtex

@article{a12f393f4593412ba6d4f49b843189bc,
title = "Development and descent of the testis in relation to cryptorchidism",
abstract = "The testis descends in two phases. Animal studies suggest, that the transabdominal descent of the testis depends on the insulin-like hormone 3 (INSL3). Androgens are important in the inguinoscrotal testicular descent in animals and humans. In general, the cause of cryptorchidism is unknown and the aetiology is possibly multifactorial. Histological changes in cryptorchid testes demonstrate disturbed development. Conclusion: Since testicular descent is regulated by testis-derived hormones, cryptorchidism may reflect a functional defect of the testis.",
keywords = "Animals, Cell Differentiation, Child, Cryptorchidism, Humans, Infant, Insulin, Leydig Cells, Male, Models, Animal, Proteins, Testis",
author = "Virtanen, {Helena E} and Dina Cortes and {Rajpert-De Meyts}, Ewa and Ritz{\'e}n, {E Martin} and Agneta Nordenskj{\"o}ld and Skakkebaek, {Niels E} and Jorma Toppari",
year = "2007",
month = may,
day = "1",
doi = "10.1111/j.1651-2227.2007.00244.x",
language = "English",
volume = "96",
pages = "622--7",
journal = "Acta Paediatrica",
issn = "0803-5253",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Development and descent of the testis in relation to cryptorchidism

AU - Virtanen, Helena E

AU - Cortes, Dina

AU - Rajpert-De Meyts, Ewa

AU - Ritzén, E Martin

AU - Nordenskjöld, Agneta

AU - Skakkebaek, Niels E

AU - Toppari, Jorma

PY - 2007/5/1

Y1 - 2007/5/1

N2 - The testis descends in two phases. Animal studies suggest, that the transabdominal descent of the testis depends on the insulin-like hormone 3 (INSL3). Androgens are important in the inguinoscrotal testicular descent in animals and humans. In general, the cause of cryptorchidism is unknown and the aetiology is possibly multifactorial. Histological changes in cryptorchid testes demonstrate disturbed development. Conclusion: Since testicular descent is regulated by testis-derived hormones, cryptorchidism may reflect a functional defect of the testis.

AB - The testis descends in two phases. Animal studies suggest, that the transabdominal descent of the testis depends on the insulin-like hormone 3 (INSL3). Androgens are important in the inguinoscrotal testicular descent in animals and humans. In general, the cause of cryptorchidism is unknown and the aetiology is possibly multifactorial. Histological changes in cryptorchid testes demonstrate disturbed development. Conclusion: Since testicular descent is regulated by testis-derived hormones, cryptorchidism may reflect a functional defect of the testis.

KW - Animals

KW - Cell Differentiation

KW - Child

KW - Cryptorchidism

KW - Humans

KW - Infant

KW - Insulin

KW - Leydig Cells

KW - Male

KW - Models, Animal

KW - Proteins

KW - Testis

U2 - 10.1111/j.1651-2227.2007.00244.x

DO - 10.1111/j.1651-2227.2007.00244.x

M3 - Journal article

C2 - 17462055

VL - 96

SP - 622

EP - 627

JO - Acta Paediatrica

JF - Acta Paediatrica

SN - 0803-5253

IS - 5

ER -

ID: 34345351