Thomas Werge
Clinical Professor
- 2024
- Published
100 ancient genomes show repeated population turnovers in Neolithic Denmark
Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, , 2024, In: Nature. 625, 7994, p. 329-337 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Polygenic Analyses Show Important Differences Between Major Depressive Disorder Symptoms Measured Using Various Instruments
Huang, L., Tang, S., Rietkerk, J., Appadurai, V., Krebs, M. D., Schork, A. J., Werge, Thomas, Zuber, V., Kendler, K. & Cai, N., 2024, (Accepted/In press) In: Biological Psychiatry. 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder
LaBianca, S., Brikell, I., Helenius, D., Loughnan, R., Mefford, J., Palmer, C. E., Walker, R., Gådin, J. R., Krebs, M., Appadurai, V., Vaez, M., Agerbo, E., Pedersen, M. G., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B., Kendler, K. S., Jernigan, T. L. & 7 others, , 2024, In: Nature Genetics. 56, 2, p. 234-244 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genomics of post-glacial western Eurasia
Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., da Mota, B. S., Paulsson, B. S., Halgren, A., Macleod, R., Jørkov, M. L. S., Demeter, F., Sørensen, L., Nielsen, P. O., Henriksen, R. A., Vimala, T. & 144 others, , 2024, In: Nature. 625, 7994, p. 301-311Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- E-pub ahead of print
Identification of women at high risk of postpartum psychiatric episodes: A population-based study quantifying relative and absolute risks following exposure to selected risk factors and genetic liability
Johannsen, B. M. W., Larsen, J. T., Liu, X., Madsen, K. B., Mægbæk, M. L., Albiñana, C., Bergink, V., Laursen, T. M., Bech, B. H., Mortensen, P. B., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Hougaard, D. M., Agerbo, E., Petersen, L. V. & Munk-Olsen, T., 23 Oct 2023, (E-pub ahead of print) In: Acta Psychiatrica Scandinavica. 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A study of the genetic architecture of social responsiveness in families with parental schizophrenia or bipolar disorder and population-based controls
Veddum, L., Greve, A. N., Gregersen, M., Andreassen, A. K., Knudsen, C. B., Brandt, J. M., Krantz, M. F., Søndergaard, A., Burton, B. K., Jepsen, J. R. M., Hemager, N., Werge, Thomas, Thorup, Anne, Nordentoft, Merete, Mors, O. & Nudel, R., 2023, In: Psychiatry Research. 326, 115280.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADuLT: An efficient and robust time-to-event GWAS
Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Steinbach, J., Krebs, M. D., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Børglum, A. D., Musliner, K. L., Ganna, A., Schork, A. J., Mortensen, P. B., McGrath, J. J., Privé, F. & Vilhjálmsson, B. J., 2023, In: Nature Communications. 14, 12 p., 5553.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks
Appadurai, V., Bybjerg-Grauholm, J., Krebs, M. D., Rosengren, A., Buil, A., Ingason, A., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Delaneau, O., Werge, Thomas & Schork, A. J., 2023, In: Communications Biology . 6, 101.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample
Nudel, R., Allesøe, R. L., Werge, Thomas, Thompson, W. K., Rasmussen, Simon & Benros, Michael Eriksen, 2023, In: Immunology. 168, 4, p. 622-639Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study
Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Geschwind, D. H., Buil Demur, Alfonso Alberto, Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, Thomas & Ingason, A., 2023, In: The Lancet Psychiatry. 10, 2, p. 129-138 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark
Shen, Q., Joyce, E. E., Ebrahimi, O. V., Didriksen, M., Lovik, A., Sævarsdóttir, K. S., Magnúsdóttir, I., Mikkelsen, D. H., Unnarsdóttir, A. B., Hauksdóttir, A., Hoffart, A., Kähler, A. K., Thórdardóttir, E. B., Eythórsson, E., Frans, E. M., Tómasson, G., Ask, H., Hardardóttir, H., Jakobsdóttir, J., Lehto, K. & 12 others, , 2023, In: The Lancet Regional Health - Europe. 35, 12 p., 100756.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study
Pan, M., Roe, J. M., Nudel, R., Schork, A. J., Iakunchykova, O., Fjell, A. M., Walhovd, K. B., Werge, Thomas, Chen, C., Benros, Michael Eriksen & Wang, Y., 2023, In: Translational Psychiatry. 13, 174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: The Danish Blood Donor Study
Erikstrup, C., Sørensen, E., Nielsen, K. R., Bruun, M. T., Petersen, M. S., Rostgaard, K., Thørner, L. W., Larsen, M., Mikkelsen, S., Dinh, K. M., Schwinn, M., Rigas, A. S., Didriksen, M., Dowsett, J., von Stemann, J. H., Brodersen, T., Paulsen, I. W., Hindhede, L., Sækmose, S. G., Kaspersen, K. A. & 10 others, , 2023, In: International Journal of Epidemiology. 52, 3, p. e162-e171 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA-methylation and immunological response in medication overuse headache
Carlsen, L. N., Hansen, C. S., Kogelman, L. J. A., Werge, Thomas, Ullum, H., Bybjerg-Grauholm, J., Hansen, Thomas Folkmann & Jensen, Rigmor Højland, 2023, In: Cephalalgia. 43, 3, p. 1-11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals
Banasik, K., Møller, P. L., Techlo, T. R., Holm, P. C., Walters, G. B., Ingason, A., Rosengren, A., Rohde, P. D., Kogelman, L. J. A., Westergaard, D., Siggaard, T., Chmura, P. J., Chalmer, M. A., Magnússon, Ó., Þórisson, G., Stefánsson, H., Guðbjartsson, D. F., Stefánsson, K., Olesen, J., Winther, S. & 5 others, , 2023, In: BMC Genomic Data. 24, 1, 4 p., 30.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Deep Learning for Cross-Diagnostic Prediction of Mental Disorder Diagnosis and Prognosis Using Danish Nationwide Register and Genetic Data
Allesøe, R. L., Thompson, W. K., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2023, In: JAMA Psychiatry. 80, 2, p. 146-155 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses
Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G., Thorgeirsson, T. & 23 others, , 2023, In: Nature Medicine. 29, 7, p. 1832-1844 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developmental language disorder – a comprehensive study of more than 46,000 individuals
Nudel, R., Christensen, Rikke Vang, Kalnak, N., Schwinn, M., Banasik, Karina, Dinh, K. M., Erikstrup, C., Pedersen, Ole Birger Vesterager, Burgdorf, Kristoffer Sølvsten, Ullum, H., Ostrowski, Sisse Rye, Hansen, Thomas Folkmann, Werge, Thomas & DBDS Genomic Consortium, D. G. C., 2023, In: Psychiatry Research. 323, 9 p., 115171.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers
Pasman, J. A., Meijsen, J. J., Haram, M., Kowalec, K., Harder, A., Xiong, Y., Nguyen, T-D., Jangmo, A., Shorter, J. R., Bergstedt, J., Das, U., Zetterberg, R., Tate, A., Lichtenstein, P., Larsson, H., Odsbu, I., Werge, T., Reichborn-Kjennerud, T., Andreassen, O. A., Sullivan, P. F. & 3 others, , 2023, In: The Lancet Regional Health - Europe. 29, 12 p., 100621.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Experience of loneliness during the COVID-19 pandemic: a cross-sectional study of 50 968 adult Danes
Christoffersen, L. A. N., Helenius, D., Schwinn, M., Erikstrup, C., Hjalgrim, Henrik, Nissen, J., Banasik, Karina, Nielsen, K., Kaspersen, K. A., Dinh, K. M., Bruun, M. T., Ostrowski, Sisse Rye, Sækmose, S., Hansen, Thomas Folkmann, Werge, Thomas, Didriksen, M. & Pedersen, Ole Birger Vesterager, 2023, In: BMJ Open. 13, 4, 9 p., e064033.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors
Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J. E., Murnyak, B., Wendt, F., Adams, M., Campos, A. I., DiBlasi, E., Fullerton, J. M., Kranzler, H. R., Bakian, A. V., Monson, E. T., Rentería, M. E., Walss-Bass, C., Andreassen, O. A., Behera, C. & 228 others, , 2023, In: American Journal of Psychiatry. 180, 10, p. 723-738 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and epidemiological analyses of infection load and its relationship with psychiatric disorders
Nudel, R., Hougaard, D. M., Werge, Thomas & Benros, Michael Eriksen, 2023, In: Epidemiology and Infection. 151, 11 p., e93.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots
Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., Vilhjálmsson, B. J. & 1 others, , 2023, In: Nature Communications. 14, 16 p., 852.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic liability to posttraumatic stress disorder and its association with postpartum depression
Bang Madsen, K., Liu, X., Albiñana, C., Jóhann Vilhjálmsson, B., Agerbo, E., Mortensen, P. B., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Mors, O., Børglum, A. D. & Munk-Olsen, T., 2023, In: Psychological Medicine. 53, 11, p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains: [Inkl. Correction]
Demontis, D., Walters, G. B., Athanasiadis, G., Walters, R., Therrien, K., Nielsen, T. T., Farajzadeh, L., Voloudakis, G., Bendl, J., Zeng, B., Zhang, W., Grove, J., Als, T. D., Duan, J., Satterstrom, F. K., Bybjerg-Grauholm, J., Bækved-Hansen, M., Gudmundsson, O. O., Magnusson, S. H., Baldursson, G. & 32 others, , 2023, In: Nature Genetics. 55, p. 198–208 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
Beaumont, R. N., Flatley, C., Vaudel, M., Wu, X., Chen, J., Moen, G. H., Skotte, L., Helgeland, Ø., Solé-Navais, P., Banasik, K., Albiñana, C., Ronkainen, J., Fadista, J., Stinson, S. E., Trajanoska, K., Wang, C. A., Westergaard, D., Srinivasan, S., Sánchez-Soriano, C., Bilbao, J. R. & 68 others, , 2023, In: Nature Genetics. 55, 11, p. 1807-1819 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity
Rajagopal, V. M., Ganna, A., Coleman, J. R. I., Allegrini, A., Voloudakis, G., Grove, J., Als, T. D., Horsdal, H. T., Petersen, L., Appadurai, V., Schork, A., Buil, A., Bulik, C. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mors, O., Nordentoft, M., Werge, T., Mortensen, P. B. & 7 others, , 2023, In: Scientific Reports. 13, 16 p., 429.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample
Suppli, N. P., Andersen, K. K., Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-grauholm, J., Bækvad-hansen, M., Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O. & 3 others, , 2023, In: Biological Psychiatry Global Open Science. 2, 4, p. 400-410 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study
Brikell, I., Wimberley, T., Albiñana, C., Vilhjálmsson, B. J., Agerbo, E., Børglum, A. D., Demontis, D., Schork, A. J., LaBianca, S., Werge, Thomas, Hougaard, D. M., Nordentoft, Merete, Mors, O., Mortensen, P. B., Petersen, L. V. & Dalsgaard, S., 2023, In: The American Journal of Psychiatry. 180, 1, p. 73-88 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression
Guintivano, J., Byrne, E. M., Kiewa, J., Yao, S., Bauer, A. E., Aberg, K. A., Adams, M. J., Campbell, A., Campbell, M. L., Choi, K. W., Corfield, E. C., Havdahl, A., Hucks, D., Koen, N., Lu, Y., Mægbæk, M. L., Mullaert, J., Peterson, R. E., Raffield, L. M., Sallis, H. M. & 59 others, , 2023, In: The American Journal of Psychiatry. 180, 12, p. 884-895 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic signature of the pathogenic 22q11.2 deletion identifies carriers and provides insight into systemic dysregulation
Courraud, J., Russo, F., Themudo, G. E., Laursen, S. S., Ingason, A., Hougaard, D. M., Cohen, A. S., Werge, Thomas & Ernst, M., 2023, In: Translational Psychiatry. 13, 7 p., 391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-PGS enhances polygenic prediction by combining 937 polygenic scores
Albiñana, C., Zhu, Z., Schork, A. J., Ingason, A., Aschard, H., Brikell, I., Bulik, C. M., Petersen, L. V., Agerbo, E., Grove, J., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., McGrath, J. J., Neale, B. M., Privé, F. & Vilhjálmsson, B. J., 2023, In: Nature Communications. 14, 11 p., 4702.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder
Dahl, A., Thompson, M., An, U., Krebs, M., Appadurai, V., Border, R., Bacanu, S., Werge, Thomas, Flint, J., Schork, A. J., Sankararaman, S., Kendler, K. S. & Cai, N., 2023, In: Nature Genetics. 55, 12, p. 2082-2093Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic liability, stressful life events and risk for secondary-treated depression in early life: a nationwide register-based case-cohort study
Musliner, K. L., Andersen, K. K., Agerbo, E., Albiñana, C., Vilhjalmsson, B. J., Rajagopal, V. M., Bybjerg-Grauholm, J., Bækved-Hansen, M., Pedersen, C. B., Pedersen, M. G., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B. & 2 others, , 2023, In: Psychological Medicine. 53, p. 217–226 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders
Munk-Olsen, T., Di Florio, A., Madsen, K. B., Albiñana, C., Mægbæk, M. L., Bergink, V., Frøkjær, Vibe Gedsø, Agerbo, E., Vilhjálmsson, B. J., Werge, Thomas, Nordentoft, Merete, Hougaard, D. M., Børglum, A. D., Mors, O., Mortensen, P. B. & Liu, X., 2023, In: Translational Psychiatry. 13, 1, 7 p., 346.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura
Bjornsdottir, G., Chalmer, M. A., Stefansdottir, L., Skuladottir, A. T., Einarsson, G., Andresdottir, M., Beyter, D., Ferkingstad, E., Gretarsdottir, S., Halldorsson, B. V., Halldorsson, G. H., Helgadottir, A., Helgason, H., Hjorleifsson Eldjarn, G., Jonasdottir, A., Jonasdottir, A., Jonsdottir, I., Knowlton, K. U., Nadauld, L. D., Lund, S. H. & 30 others, , 2023, In: Nature Genetics. 55, 11, p. 1843-1853Research output: Contribution to journal › Journal article › Research › peer-review
- Published
School performance and genetic propensities for educational attainment and depression in the etiology of self-harm: a Danish population-based study
Sørensen, H. J., Antonsen, S., Benros, Michael Eriksen, Erlangsen, A., Albiñana, C., Nordentoft, Merete, Børglum, A. D., Mors, O., Werge, Thomas, Mortensen, P. B., Hougaard, D., Webb, R. T. & Agerbo, E., 2023, In: Nordic Journal of Psychiatry. 77, 2, p. 179-187 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders
Borbye-Lorenzen, N., Zhu, Z., Agerbo, E., Albiñana, C., Benros, M. E., Bian, B., Børglum, A. D., Bulik, C. M., Debost, J-C. P. G., Grove, J., Hougaard, D. M., McRae, A. F., Mors, O., Mortensen, P. B., Musliner, K. L., Nordentoft, M., Petersen, L. V., Privé, F., Sidorenko, J., Skogstrand, K. & 4 others, , 2023, In: Cell Genomics. 3, 12, 23 p., 100457.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement
Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Baekvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, Merete, Borglum, A. D., Werge, Thomas, Melbye, M., Hougaard, D. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Christiansen, M., 2023, In: Brain Communications. 5, 1, 14 p., fcad004.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic history of Scandinavia from the Roman Iron Age to the present
Rodríguez-Varela, R., Moore, K. H. S., Ebenesersdóttir, S. S., Kilinc, G. M., Kjellström, A., Papmehl-Dufay, L., Alfsdotter, C., Berglund, B., Alrawi, L., Kashuba, N., Sobrado, V., Lagerholm, V. K., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T. & 24 others, , 2023, In: Cell. 186, 1, p. 32-46.e19Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective
Nudel, R., Thompson, W. K., Børglum, A. D., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete & Benros, Michael Eriksen, Dec 2022, In: Translational Psychiatry. 12, 1, 9 p., 334.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?
Jürgens, Gesche, Kaas-Hansen, Benjamin Skov, Nordentoft, Merete, Werge, Thomas & Andersen, Stig Ejdrup, Oct 2022, In: Journal of Personalized Medicine. 12, 10, 12 p., 1728.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elucidating the relationship between migraine risk and brain structure using genetic data
International Headache Genetics Consortium, I. H. G. C., 1 Sep 2022, In: Brain. 145, 9, p. 3214-3224 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancing discovery of genetic variants for PTSD through integration of quantitative phenotypes and trauma exposure information
Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B. & 161 others, , 1 Apr 2022, In: Biological Psychiatry. 91, 7, p. 626-636 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Family disadvantage, gender, and the returns to genetic human capital
Ronda, V., Agerbo, E., Bleses, D., Mortensen, P. B., Borglum, A., Mors, O., Rosholm, M., Hougaard, D. M., Nordentoft, Merete & Werge, Thomas, Apr 2022, In: Scandinavian Journal of Economics. 124, 2, p. 550-578 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy
Athanasiadis, G., Meijsen, J. J., Helenius, D., Schork, A. J., Ingason, A., Thompson, W. K., Geschwind, D. H., Werge, Thomas & Buil, A., 2022, In: PNAS. 119, 6, 9 p., e2118688119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions
Nudel, R., Zetterberg, R., Hemager, N., Christiani, C. A. J., Ohland, J., Burton, B. K., Greve, A. N., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Bybjerg-Grauholm, J., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Mors, O. & Nordentoft, Merete, 2022, In: Behavioral and Brain Functions. 18, 14.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A saturated map of common genetic variants associated with human height
Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, , 2022, In: Nature. 610, p. 704–712Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accounting for age of onset and family history improves power in genome-wide association studies
Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J., Privé, F. & 1 others, , 2022, In: American Journal of Human Genetics. 109, 3, p. 417-432 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accumulation of Disadvantages Across Multiple Domains Amongst Subgroups of Children of Parents with Schizophrenia or Bipolar Disorder: Clustering Data from the Danish High Risk and Resilience Study VIA 7
Krantz, M. F., Ellersgaard, D., Andersen, K. K., Hemager, N., Christiani, C., Spang, K. S., Burton, B. K., Gregersen, M., Søndergaard, A., Greve, A., Gantriis, D. L., Ohland, J., Mortensen, P. B., Werge, T., Nudel, R., Wang, Y., Hougaard, D. M., Plessen, K. J., Bliksted, V., Jepsen, J. R. M. & 3 others, , 2022, In: Schizophrenia Bulletin Open. 3, 1, 16 p., sgac010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accurate and Effective Detection of Recurrent Copy Number Variants in Large SNP Genotype Datasets
Montalbano, S., Sánchez, X. C., Vaez, M., Helenius, D., Werge, Thomas & Ingason, A., 2022, In: Current Protocols. 2, 12, 21 p., e621.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations
Unnarsdóttir, A. B., Lovik, A., Fawns-Ritchie, C., Ask, H., Kõiv, K., Hagen, K., Didriksen, M., Christoffersen, L. A. N., Garðarsson, A. B., McIntosh, A., Kähler, A. K., Campbell, A., Hauksdóttir, A., Erikstrup, C., Mikkelsen, D. H., Altschul, D., Thordardottir, E. B., Frans, E. M., Kvale, G., Tómasson, G. & 32 others, , 2022, In: International Journal of Epidemiology. 51, 3, p. e108–e122 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Watson, H. J., Thornton, L. M., Yilmaz, Z., Baker, J. H., Coleman, J. R. I., Adan, R. A. H., Alfredsson, L., Andreassen, O. A., Ask, H., Berrettini, W. H., Boehnke, M., Boehm, I., Boni, C., Buehren, K., Bulant, J., Burghardt, R., Chang, X., Cichon, S., Cone, R. D., Courtet, P. & 157 others, , 2022, In: Biological Psychiatry Global Open Science. 2, 4, p. 368-378 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparing Copy Number Variations in a Danish Case Cohort of Individuals with Psychiatric Disorders
Calle Sánchez, X., Helenius, D., Bybjerg-Grauholm, J., Pedersen, C., Hougaard, D. M., Børglum, A. D., Nordentoft, Merete, Mors, O., Mortensen, P. B., Geschwind, D. H., Montalbano, S., Raznahan, A., Thompson, W. K., Ingason, A. & Werge, Thomas, 2022, In: JAMA Psychiatry. 79, 1, p. 59-69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci
Fadista, J., Skotte, L., Karjalainen, J., Abner, E., Sørensen, E., Ullum, H., Werge, Thomas, Esko, T., Milani, L., Palotie, A., Daly, M., Melbye, M., Feenstra, B., Geller, F., IPSYCH Grp, I. G. & FinnGen Consortium, F. C., 2022, In: Nature Communications. 13, 11 p., 3200.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cross-trait assortative mating is widespread and inflates genetic correlation estimates
Border, R., Athanasiadis, G., Buil Demur, Alfonso Alberto, Schork, A. J., Cai, N., Young, A. I., Werge, Thomas, Flint, J., Kendler, K. S., Sankararaman, S., Dahl, A. W. & Zaitlen, N. A., 2022, In: Science. 378, 6621, p. 754-761 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells
Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.Research output: Contribution to journal › Review › Research › peer-review
- Published
Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression
Allesøe, R. L., Nudel, R., Thompson, W. K., Wang, Y., Nordentoft, Merete, Børglum, A. D., Hougaard, D. M., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2022, In: Science Advances. 8, 26, eabi7293.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder
Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B., Ribasés, M. & 2 others, , 2022, In: Nature Genetics. 54, 8, p. 1117-1124 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Mullins, N., Kang, J. E., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., Su, M. H., Watson, H. J., Adams, M., Awasthi, S., Gandal, M., Hafferty, J. D., Hishimoto, A., Kim, M., Okazaki, S., Otsuka, I. & 36 others, , 2022, In: Biological Psychiatry. 91, 3, p. 313-327 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism
Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B., Grove, J., Kalkbrenner, A., Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Børglum, A. D., Werge, Thomas, Nordentoft, Merete, Mortensen, P. B. & Agerbo, E., 2022, In: Autism Research. 15, 1, p. 171-182Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders
Debost, J. P. G., Thorsteinsson, E., Trabjerg, B., Benros, Michael Eriksen, Albiñana, C., Vilhjalmsson, B. J., Børglum, A., Mors, O., Werge, Thomas, Mortensen, P. B., Agerbo, E. & Vogdrup, L., 2022, In: Acta Psychiatrica Scandinavica. 146, 5, p. 406-419 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic assortative mating for schizophrenia and bipolar disorder
Jefsen, O. H., Nudel, R., Wang, Y., Bybjerg-Grauholm, J., Hemager, N., Christiani, C. A. J., Burton, B. K., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Nordentoft, Merete, Mors, O. & Greve, A. N., 2022, In: European Psychiatry. 65, 1, 7 p., e53.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic correlates of phenotypic heterogeneity in autism
Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., Caceres, A. S. J., Hayward, H., Crawley, D., Faulkner, J., Sabet, J., Ellis, C., Oakley, B., Loth, E., Charman, T., Murphy, D., Holt, R. & 33 others, , 2022, In: Nature Genetics. 54, 9, p. 1293-1304 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R. & 19 others, , 2022, In: Brain. 145, 2, p. 555–568Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB
Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, M. & 14 others, , 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 622-630Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups
Mattheisen, M., Grove, J., Als, T. D., Martin, J., Voloudakis, G., Meier, S., Demontis, D., Bendl, J., Walters, R., Carey, C. E., Rosengren, A., Strom, N. I., Hauberg, M. E., Zeng, B., Hoffman, G., Zhang, W., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Agerbo, E., Cormand, B. & 14 others, , 2022, In: Nature Genetics. 54, p. 1470–1478Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Infection Polygenic Factors Account for a Small Proportion of the Relationship Between Infections and Mental Disorders
Shorter, J. R., Meijsen, J., Nudel, R., Krebs, M., Gådin, J., Mikkelsen, D. H., Nogueira Avelar e Silva, R., Benros, Michael Eriksen, Thompson, W. K., Ingason, A. & Werge, Thomas, 2022, In: Biological Psychiatry. 92, 4, p. 283-290Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Life-time Actionable Pharmacogenetic Drug Use: A Population-based Cohort Study in 86 040 Young People with and without Mental Disorders in Denmark
Lunenburg, C. A. T. C., Ishtiak-Ahmed, K., Werge, Thomas & Gasse, C., 2022, In: Pharmacopsychiatry. 55, 2, p. 95-107Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C. Y., Dennison, C. A., Hall, L. S., Lam, M., Watanabe, K., Frei, O., Ge, T., Harwood, J. C., Koopmans, F., Magnusson, S., Richards, A. L., Sidorenko, J., Wu, Y. & 35 others, , 2022, In: Nature. 604, 7906, p. 502-508 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population Genomics of Stone Age Eurasia
Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., Mota, B., Paulsson, B. S., Halgren, A., Macleod, R., Schjellerup Jørkov, M. L., Demeter, F., Novosolov, M., Sørensen, L., Nielsen, P-O., Henriksen, R. H. A. & 143 others, , 2022, p. 1-71, (bioRxiv).Research output: Working paper › Preprint › Research
- Published
Prevalence of major depressive disorder in 51,658 otherwise healthy adult Danes: Sex differences in symptomatology and prediction of future anti-depressive medication
Mikkelsen, Christina, Larsen, M. A. H., Sørensen, E., Hansen, Thomas Folkmann, Mikkelsen, S., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Kessing, Lars Vedel, Werge, Thomas, Ullum, H., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Thørner, L. W. & Didriksen, Maria, 2022, In: Psychiatry Research. 318, 7 p., 114944.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
Bjornsdottir, G., Stefansdottir, L., Thorleifsson, G., Sulem, P., Norland, K., Ferkingstad, E., Oddsson, A., Zink, F., Lund, S. H., Nawaz, M. S., Bragi Walters, G., Skuladottir, A. T., Gudjonsson, S. A., Einarsson, G., Halldorsson, G. H., Bjarnadottir, V., Sveinbjornsson, G., Helgadottir, A., Styrkarsdottir, U., Gudmundsson, L. J. & 26 others, , 2022, In: Nature Communications. 13, 13 p., 634.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare coding variants in ten genes confer substantial risk for schizophrenia
Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., Buckley, P. F., Bunney, W. E., Bybjerg-Grauholm, J., Byerley, W. F., Chapman, S. B., Chen, W. J., Churchhouse, C., Craddock, N., Cusick, C. M., DeLisi, L. & 91 others, , 2022, In: Nature. 604, 7906, p. 509-516 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, , 2022, In: Biological Psychiatry. 91, 1, p. 107-117Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p
Weiner, D. J., Ling, E., Erdin, S., Tai, D. J. C., Yadav, R., Grove, J., Fu, J. M., Nadig, A., Carey, C., Baya, N., Bybjerg-Grauholm, J., Mortensen, P. B., Werge, T., Demontis, D., Mors, O., Nordentoft, M., Als, T. D., Baekvad-Hansen, M., Rosengren, A., Havdahl, A. & 33 others, , 2022, In: Nature Genetics. 54, p. 1630-1639Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural basis of organic cation transporter-3 inhibition
Khanppnavar, B., Maier, J., Herborg, Freja, Gradisch, R., Lazzarin, E., Luethi, D., Yang, J. W., Qi, C., Holy, M., Jäntsch, K., Kudlacek, O., Schicker, K., Werge, Thomas, Gether, Ulrik, Stockner, T., Korkhov, V. M. & Sitte, H. H., 2022, In: Nature Communications. 13, 1, 13 p., 6714.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Selection Landscape and Genetic Legacy of Ancient Eurasians
Irving-Pease, E., Refoyo Martínez, A., Ingason, A., Pearson, A., Fischer, A., Barrie, W., Sjögren, K-G., Halgren, A. S., Macleod, R., Demeter, F., Henriksen, R. H. A., Vimala, T., McColl, H., Vaughn, A., Stern, A. J., Speidel, L., Scorrano, G., Ramsøe, A., Schork, A. J., Rosengren, A. & 12 others, , 2022, bioRxiv, 26 p.Research output: Working paper › Preprint › Research
- Published
The population genomic legacy of the second plague pandemic
Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, , 2022, In: Current Biology. 32, 21, p. 4743-4751.e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The sequences of 150,119 genomes in the UK Biobank
Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F., Asgeirsdottir, M. & 27 others, , 2022, In: Nature. 607Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Copy Number Variants and Polygenic Risk Scores Predict Need of Care in Autism and/or ADHD Families
LaBianca, S., LaBianca, J., Pagsberg, Anne Katrine, Jakobsen, K. D., Appadurai, V., Buil, A. & Werge, Thomas, Jan 2021, In: Journal of Autism and Developmental Disorders. 51, 1, p. 276-285 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Bell, S., Rigas, A. S., Magnusson, M. K., Ferkingstad, E., Allara, E., Bjornsdottir, G., Ramond, A., Sørensen, E., Halldorsson, G. H., Paul, D. S., Burgdorf, K. S., Eggertsson, H. P., Howson, J. M. M., Thørner, L. W., Kristmundsdottir, S., Astle, W. J., Erikstrup, C., Sigurdsson, J. K., Vuckovic, D., Dinh, K. M. & 31 others, , 2021, In: Communications Biology . 4, 1, 14 p., 156.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders
Nudel, R., Allesøe, R. L., Thompson, W. K., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2021, In: Journal of Translational Medicine. 19, 230.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A polygenic resilience score moderates the genetic risk for schizophrenia
Hess, J. L., Tylee, D. S., Mattheisen, M., The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum, A. D., Als, T. D., Grove, J., Werge, T., Mortensen, P. B., Mors, O., Nordentoft, M., Hougaard, D. M., Byberg-grauholm, J., Bækvad-hansen, M., Greenwood, T. A., Tsuang, M. T., Curtis, D., Steinberg, S., Sigurdsson, E. & 6 others, , 2021, In: Molecular Psychiatry. 26, p. 800–815Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association and genetic overlap between clinical chemistry tests and migraine
Tanha, H. M. & The International Headache Genetics Consortium (IHGC), T. I. H. G. C. (., 2021, In: Cephalalgia. 41, 11-12, p. 1208-1221 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 46 others, , 2021, In: Molecular Psychiatry. 26, p. 2457–2470 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors
Krebs, M. D., Themudo, G. E., Benros, Michael Eriksen, Mors, O., Børglum, A. D., Hougaard, D., Mortensen, P. B., Nordentoft, Merete, Gandal, M. J., Fan, C. C., Geschwind, D. H., Schork, A. J., Werge, Thomas & Thompson, W. K., 2021, In: Nature Communications. 12, 12 p., 6617.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, , 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CYP2D6 Genotyping and Antipsychotic-Associated Extrapyramidal Adverse Effects in a Randomized Trial of Aripiprazole Versus Quetiapine Extended Release in Children and Adolescents, Aged 12-17 Years, With First Episode Psychosis
Rudå, Ditte, mfw347, mfw347, Decara, M. S., Klauber, D. G., Fagerlund, Birgitte, Møllegaard, J. R., Linnet, Kristian, Werge, Thomas, Correll, C. U., Fink-Jensen, Anders, Jürgens, Gesche & Pagsberg, Anne Katrine, 2021, In: Journal of Clinical Psychopharmacology. 41, 6, p. 667-672Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study
Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Grove, J., Nordentoft, Merete, Børglum, A. D., Mortensen, P. B., Werge, Thomas, Melbye, M., Hougaard, D. M. & Christiansen, M., 2021, In: Journal of Neurodevelopmental Disorders. 13, 9 p., 19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits
Martin, J., Khramtsova, E. A., Goleva, S. B., Blokland, G. A. M., Traglia, M., Walters, R. K., Hübel, C., Coleman, J. R. I., Breen, G., Børglum, A. D., Demontis, D., Grove, J., Werge, T., Bralten, J., Bulik, C. M., Lee, P. H., Mathews, C. A., Peterson, R. E., Winham, S. J., Wray, N. & 13 others, , 2021, In: Biological Psychiatry. 89, 12, p. 1127-1137Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic disposition towards educational attainment and intelligence test performance predict voter turnout
Aaroe, L., Appadurai, V., Hansen, Kasper Møller, Schork, A. J., Werge, Thomas, Mors, O., Borglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Thompson, W. K., Buil, A., Agerbo, E. & Petersen, M. B., 2021, In: Nature Human Behavior. 5, 2, p. 281-291 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic factors underlying the bidirectional relationship between autoimmune and mental disorders - findings from a Danish population-based study: [Incl. Corrigendum]
Liu, X., Nudel, R., Thompson, W. K., Appadurai, V., Schork, A. J., Buil, A., Rasmussen, Simon, Allesøe, R. L., Werge, Thomas, Mors, O., Børglum, A. D., Hougaard, D. M., Mortensen, P. B., Nordentoft, Merete & Benros, Michael Eriksen, 2021, In: Brain, Behavior, and Immunity. 91, p. 10-23 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study
Fadista, J., Yakimov, V., Võsa, U., Hansen, C. S., Kasela, S., Skotte, L., Geller, F., Courraud, J., Esko, T., Kukuškina, V., Buil, A., Melbye, M., Werge, Thomas, Hougaard, D. M., Milani, L., Bybjerg-Grauholm, J., Cohen, A. S. & Feenstra, B., 2021, In: Scientific Reports. 11, 17463.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD
Brikell, I., Wimberley, T., Albinana, C., Pedersen, E. M., Vilhjalmsson, B. J., Agerbo, E., Demontis, D., Borglum, A. D., Schork, A. J., LaBianca, S., Werge, Thomas, Mors, O., Hougaard, D. M., Thapar, A., Mortensen, P. B. & Dalsgaard, S., 2021, In: American Journal of Psychiatry. 178, 9, p. 854-864 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci
Foss-Skiftesvik, J., Hagen, C. M., Mathiasen, R., Adamsen, D., Bækvad-Hansen, M., Børglum, A. D., Nordentoft, Merete, Werge, Thomas, Christiansen, M., Schmiegelow, Kjeld, Juhler, Marianne, Mortensen, P. B., Hougaard, D. M. & Bybjerg-Grauholm, J., 2021, In: Child's Nervous System. 37, p. 819–830Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 48 common genetic variants associated with handedness
Cuellar-Partida, G., Tung, J. Y., Eriksson, N., Albrecht, E., Aliev, F., Andreassen, O. A., Barroso, I., Beckmann, J. S., Boks, M. P., Boomsma, D. I., Boyd, H. A., Breteler, M. M. B., Campbell, H., Chasman, D. I., Cherkas, L. F., Davies, G., de Geus, E. J. C., Deary, I. J., Deloukas, P., Dick, D. M. & 98 others, , 2021, In: Nature Human Behaviour. 5, p. 59-70Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
HUNT All-In Psychiatry, H. A. P., 2021, In: Nature Genetics. 53, 6, p. 817-829 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression
Forstner, A. J., Awasthi, S., Wolf, C., Maron, E., Erhardt, A., Czamara, D., Eriksson, E., Lavebratt, C., Allgulander, C., Friedrich, N., Becker, J., Hecker, J., Rambau, S., Conrad, R., Geiser, F., Mcmahon, F. J., Moebus, S., Hess, T., Buerfent, B. C., Hoffmann, P. & 55 others, , 2021, In: Molecular Psychiatry. 26, p. 4179–4190 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gestational age-dependent development of the neonatal metabolome
Ernst, M., Rogers, S., Lausten-Thomsen, U., Björkbom, A., Laursen, S. S., Courraud, J., Borglum, A., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Hougaard, D. M. & Cohen, A. S., 2021, In: Pediatric Research. 89, p. 1396–1404 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of genetic loci associated with nocturnal enuresis: a genome-wide association study
Jørgensen, C. S., Horsdal, H. T., Rajagopal, V. M., Grove, J., Als, T. D., Kamperis, K., Nyegaard, M., Walters, G. B., Eðvarðsson, V. Ö., Stefánsson, H., Nordentoft, M., Hougaard, D. M., Werge, T., Mors, O., Mortensen, P. B., Agerbo, E., Rittig, S., Stefánsson, K., Børglum, A. D., Demontis, D. & 1 others, , 2021, In: The Lancet Child & Adolescent Health. 5, 3, p. 201-209Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identifying dominant-negative actions of a dopamine transporter variant in patients with parkinsonism and neuropsychiatric disease
Herborg, F., Jensen, K. L., Tolstoy, S., Arends, N., Posselt, L. P., Shekar, A., Aguilar, J., Lund, V. K., Erreger, K., Rickhag, M., Lycas, M. D., Lonsdale, M. N., Rahbek-Clemmensen, T., Sorensen, A. T., Newman, A. H., Lokkegaard, A., Kjaerulff, O., Werge, T., Moller, L. B., Matthies, H. J. G. & 4 others, , 2021, In: JCI insight. 6, 18, 21 p., 151496.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life - A Large Prospective Cohort Study on Adult Danes
Didriksen, Maria, Werge, Thomas, Nissen, J., Schwinn, M., Sørensen, E., Nielsen, K. R., Bruun, M. T., Banasik, Karina, Hansen, T. F., Erikstrup, C., Ostrowski, Sisse Rye, Jennum, Poul, Hjalgrim, Henrik, Ullum, H. & Pedersen, Ole Birger Vesterager, 2021, In: International Journal of Environmental Research and Public Health. 18, 14, 14 p., 7610.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is the Association between Parents' Mental Illness and Child Psychopathology Mediated via Home Environment and Caregiver's Psychosocial Functioning? A Mediation Analysis of the Danish High Risk and Resilience Study-VIA7, a Population-Based Cohort Study
Uddin, M. J., Ekstrøm, C. T., Hemager, N., Christiani, C. A. J., Gregersen, M., Ellersgaard, D. V., Spang, K. S., Greve, A., Burton, B. K., Søndergaard, A., Nudel, R., Mortensen, P. B., Pedersen, M. G., Pedersen, C. B., Wang, Y., Werge, T., Bybjerg-Grauholm, J., Von Plessen, K. J., Bliksted, V., Mors, O. & 2 others, , 2021, In: Schizophrenia Bulletin Open. 2, 1, 12 p., sgab024.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction
Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J., 2021, In: American Journal of Human Genetics. 108, 6, p. 1001-1011 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No evidence of associations between genetic liability for schizophrenia and development of cannabis use disorder
Hjorthøj, Carsten, Uddin, M. J., Wimberley, T., Dalsgaard, S., Hougaard, D. M., Borglum, A., Werge, Thomas & Nordentoft, Merete, 2021, In: Psychological Medicine. 51, 3, p. 479-484 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacogenetic genotype and phenotype frequencies in a large Danish population-based case-cohort sample
Lunenburg, C. A. T. C., Thirstrup, J. P., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Børglum, A. D., Mors, O., Mortensen, P. B. & Gasse, C., 2021, In: Translational Psychiatry. 11, 1, 294.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropy between language impairment and broader behavioral disorders—an investigation of both common and rare genetic variants
Nudel, R., Appadurai, V., Buil, A., Nordentoft, Merete & Werge, Thomas, 2021, In: Journal of Neurodevelopmental Disorders. 13, 15 p., 54.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis
Strom, N. I., Grove, J., Meier, S. M., Bækvad-Hansen, M., Becker Nissen, J., Damm Als, T., Halvorsen, M., Nordentoft, Merete, Mortensen, P. B., Hougaard, D. M., Werge, Thomas, Mors, O., Børglum, A. D., Crowley, J. J., Bybjerg-Grauholm, J. & Mattheisen, M., 2021, In: Frontiers in Genetics. 12, 711624.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship Between Major Depressive Disorder (Mdd) Symptoms and Mdd Heterogeneity
Huang, L., Tang, S., Krebs, M. D., Schork, A. J., Werge, Thomas, Dahl, A., Zuber, V. & Cai, N., 2021, In: Genetic Epidemiology. 45, 7, p. 761-761 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status
Agerbo, E., Trabjerg, B. B., Børglum, A. D., Schork, A. J., Vilhjálmsson, B. J., Pedersen, C. B., Hakulinen, C., Albiñana, C., Hougaard, D. M., Grove, J., McGrath, J. J., Bybjerg-Grauholm, J., Mors, O., Plana-Ripoll, O., Werge, Thomas, Wray, N. R., Mortensen, P. B. & Musliner, K. L., 2021, In: JAMA Psychiatry. 78, 4, p. 387-397 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder
Demontis, D., Walters, R. K., Rajagopal, V. M., Waldman, I. D., Grove, J., Als, T. D., Dalsgaard, S., Ribasas, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T., Nordentoft, M., Mors, O., Mortensen, P. B., Andreassen, O. A., Arranz, M. J., Banaschewski, T., Bau, C., Bellgrove, M., Biederman, J. & 31 others, , 2021, In: Nature Communications. 12, 576.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic structure of Norway
Mattingsdal, M., Ebenesersdóttir, S. S., Moore, K. H. S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kockum, I., Olsson, T., Alfredsson, L., Helgason, A., Stefánsson, K. & Hovig, E., 2021, In: European Journal of Human Genetics. 29, p. 1710–1718Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations
Gordon, A., Forsingdal, A., Klewe, I. V., Nielsen, J., Didriksen, M., Werge, Thomas & Geschwind, D. H., 2021, In: Molecular Psychiatry. 26, p. 1520–1534Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction
Sun, J., Wang, Y., Folkersen, L., Borné, Y., Amlien, I., Buil, A., Orho-Melander, M., Børglum, A. D., Hougaard, D. M., Lotta, L. A., Jones, M., Baras, A., Melander, O., Engström, G., Werge, Thomas, Lage, K. & Regeneron Genetics Center, R. G. C., 2021, In: Nature Communications. 12, 5276.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Effect of Routine Cytochrome P450 2D6 and 2C19 Genotyping on Antipsychotic Drug Persistence in Patients With Schizophrenia: A Randomized Clinical Trial
Jürgens, Gesche, Andersen, Stig Ejdrup, Rasmussen, H. B., Werge, Thomas, Jensen, H. D., Kaas-Hansen, Benjamin Skov & Nordentoft, Merete, 1 Dec 2020, In: JAMA Network Open. 3, 12, p. e2027909Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of the genetic liability on the association between infections and autism
Shorter, J., Krebs, M., Ingason, A., Benros, Michael Eriksen, Thompson, W. & Werge, Thomas, Dec 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 719-720 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
Bryois, J., Skene, N. G., Hansen, T. F., Kogelman, L. J. A., Watson, H. J., Liu, Z., Eating Disorders Working Group of the Psychiatric Genomics Consortium, Adan, R., Alfredsson, L., Ando, T., Andreassen, O., Baker, J., Bergen, A., Berrettini, W., Birgegård, A., Boden, J., Boehm, I., Boni, C., Boraska Perica, V., Brandt, H. & 44 others, , May 2020, In: Nature Genetics. 52, p. 482-493Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank
Coleman, J. R. I., Peyrot, W. J., Purves, K. L., Davis, K. A. S., Rayner, C., Choi, S. W., Hübel, C., Gaspar, H. A., Kan, C., Van der Auwera, S., Adams, M. J., Lyall, D. M., Choi, K. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 31 others, , May 2020, In: Molecular Psychiatry. 25, p. 1430-1446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large population-based investigation into the genetics of susceptibility to gastrointestinal infections and the link between gastrointestinal infections and mental illness
Nudel, R., Appadurai, V., Schork, A. J., Buil, A., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, Mar 2020, In: Human Genetics. 139, p. 593-604Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses
Ahluwalia, T. S., Eliasen, A. U., Sevelsted, A., Pedersen, C-E. T., Stokholm, J., Chawes, B., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Sharma, A., Weiss, S. T., Evans, M. D., Jackson, D. J., Morin, A., Krogfelt, K. A., Schjørring, S., Mortensen, P. B., Hougaard, D. M. & 13 others, , 2020, In: Nature Communications. 11, 12 p., 6398.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, , 2020, In: Nature Communications. 11, 1, 3368.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large-scale genome-wide association study meta-analysis of cannabis use disorder
Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., Sanchez-Roige, S., Paul, S. E., Wendt, F. R., Clarke, T. K., Lai, D., Reginsson, G. W., Zhou, H., He, J., Baranger, D. A. A., Gudbjartsson, D. F., Wedow, R., Adkins, D. E., Adkins, A. E., Alexander, J. & 31 others, , 2020, In: The Lancet Psychiatry. 7, 12, p. 1032-1045 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A major role for common genetic variation in anxiety disorders
Purves, K. L., Coleman, J. R. I., Meier, S. M., Rayner, C., Davis, K. A. S., Cheesman, R., Bækvad-Hansen, M., Børglum, A. D., Wan Cho, S., Jürgen Deckert, J., Gaspar, H. A., Bybjerg-Grauholm, J., Hettema, J. M., Hotopf, M., Hougaard, D., Hübel, C., Kan, C., McIntosh, A. M., Mors, O., Bo Mortensen, P. & 6 others, , 2020, In: Molecular Psychiatry. 25, p. 3292–3303Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Shen, X., Howard, D. M., Adams, M. J., Hill, W. D., Clarke, T. K., Adams, M. J., Clarke, T. K., McIntosh, A. M., Deary, I. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M. & 31 others, , 2020, In: Nature Communications. 11, 1, 2301.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression
Paksarian, D., Trabjerg, B. B., Merikangas, K. R., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Pedersen, C. B., Mortensen, P. B., Agerbo, E. & Horsdal, H. T., 2020, In: British Journal of Psychiatry. 217, 1, p. 390-396 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of genes within the schizophrenia-linked 22q11.2 deletion identifies interaction of night owl/LZTR1 and NF1 in GABAergic sleep control
Maurer, G. W., Malita, Alina, Nagy, S., Koyama, Takashi, Werge, Thomas, Halberg, Kenneth Veland, Texada, Michael James & Rewitz, Kim, 2020, In: PLOS Genetics. 16, 4, 31 p., e1008727.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association Between Childhood Green Space, Genetic Liability, and the Incidence of Schizophrenia
Engemann, K., Pedersen, C. B., Agerbo, E., Arge, L., Børglum, A. D., Erikstrup, C., Hertel, O., Hougaard, D. M., McGrath, J. J., Mors, O., Mortensen, P. B., Nordentoft, Merete, Sabel, C. E., Sigsgaard, T., Tsirogiannis, C., Vilhjálmsson, B. J., Werge, Thomas, Svenning, J. C. & Horsdal, H. T., 2020, In: Schizophrenia Bulletin. 46, 6, p. 1629-1637 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between GLP-1 receptor gene polymorphisms with reward Learning, anhedonia, and depression diagnosis
Eser, H. Y., Appadurai, V., Eren, C. Y., Yazici, D., Chen, C. Y., Ongur, D., Pizzagalli, D. A., Werge, Thomas & Hall, M. H., 2020, In: Acta Neuropsychiatrica. 32, 4, p. 218-225Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between Mental Disorders and Subsequent Medical Conditions
Momen, N. C., Plana-Ripoll, O., Agerbo, E., Benros, M. E., Børglum, A. D., Christensen, M. K., Dalsgaard, S., Degenhardt, L., de Jonge, P., Debost, J-C. P. G., Fenger-Grøn, M., Gunn, J. M., Iburg, K. M., Kessing, L. V., Kessler, R. C., Laursen, T. M., Lim, C. C. W., Mors, O., Mortensen, P. B., Musliner, K. L. & 18 others, , 2020, In: The New England Journal of Medicine. 382, 18, p. 1721-1731 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral small vessel disease genomics and its implications across the lifespan
Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S. P., Kumar, R. B., van den Akker, E. B., McWhirter, R. E., Trompet, S., Mishra, A. & 32 others, , 2020, In: Nature Communications. 11, 1, 18 p., 6285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
Glanville, K. P., Coleman, J. R. I., Hanscombe, K. B., Euesden, J., Choi, S. W., Purves, K. L., Breen, G., Air, T. M., Andlauer, T. F. M., Baune, B. T., Binder, E. B., Blackwood, D. H. R., Boomsma, D. I., Buttenschøn, H. N., Colodro-Conde, L., Dannlowski, U., Direk, N., Dunn, E. C., Forstner, A. J., de Geus, E. J. C. & 31 others, , 2020, In: Biological Psychiatry. 87, 5, p. 419-430 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complement genes contribute sex-biased vulnerability in diverse disorders
Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., Taylor, K. E., Whelan, C. W., Tombleson, P., Loohuis, L. M. O., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H. & 33 others, , 2020, In: Nature. 582, 7813, p. 577-581 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic liability to ADHD and substance use disorders in individuals with ADHD
Wimberley, T., Agerbo, E., Horsdal, H. T., Ottosen, C., Brikell, I., Als, T. D., Demontis, D., Børglum, A. D., Nordentoft, Merete, Mors, O., Werge, Thomas, Hougaard, D., Bybjerg-Grauholm, J., Hansen, M. B., Mortensen, P. B., Thapar, A., Riglin, L., Langley, K. & Dalsgaard, S., 2020, In: Addiction. 115, 7, p. 1368-1377Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic liability to major depression and risk of childhood asthma
Liu, X., Munk-Olsen, T., Albiñana, C., Vilhjálmsson, B. J., Pedersen, E. M., Schlünssen, V., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Hougaard, D. M., Mortensen, P. B. & Agerbo, E., 2020, In: Brain, Behavior, and Immunity. 89, p. 433-439 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic stratification of depression in UK Biobank
Howard, D. M., Folkersen, L., Coleman, J. R., Adams, M. J., Glanville, K., Werge, Thomas, Hagenaars, S. P., Han, B., Porteous, D., Campbell, A., Clarke, T., Breen, G., Sullivan, P. F., Wray, N. R., Lewis, C. M. & McIntosh, A. M., 2020, In: Translational Psychiatry. 10, 1, 8 p., 163.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association study
Erlangsen, A., Appadurai, V., Wang, Y., Turecki, G., Mors, O., Werge, Thomas, Mortensen, P. B., Starnawska, A., Børglum, A. D., Schork, A., Nudel, R., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Thompson, W. K., Nordentoft, Merete & Agerbo, E., 2020, In: Molecular Psychiatry. 25, p. 2410–2421Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
Wang, Y., Nudel, R., Benros, Michael Eriksen, Skogstrand, K., Fishilevich, S., Lancet, D., Sun, J., Hougaard, D. M., Andreassen, O. A., Mortensen, P. B., Buil, A., Hansen, Thomas Folkmann, Thompson, W. K., Werge, Thomas & iPSYCH-BROAD, I., 2020, In: PLOS Genetics. 16, 11, e1009163.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores
Folkersen, L., Pain, O., Ingason, A., Werge, Thomas, Lewis, C. M. & Austin, J., 2020, In: Frontiers in Genetics. 11, 578.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Language deficits in specific language impairment, attention deficit/hyperactivity disorder, and autism spectrum disorder: An analysis of polygenic risk
Nudel, R., Christiani, C. A. J., Ohland, J., Uddin, M. J., Hemager, N., Ellersgaard, D. V., Spang, K. S., Burton, B. K., Greve, A. N., Gantriis, D. L., Bybjerg-Grauholm, J., Jepsen, J. R. M., Thorup, Anne, Mors, O., Nordentoft, Merete & Werge, Thomas, 2020, In: Autism Research. 13, 3, p. 369-381Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
Satterstrom, F. K., Kosmicki, J. A., Wang, J., Breen, M. S., De Rubeis, S., An, J. Y., Peng, M., Collins, R., Grove, J., Klei, L., Stevens, C., Reichert, J., Mulhern, M. S., Artomov, M., Gerges, S., Sheppard, B., Xu, X., Bhaduri, A., Norman, U., Brand, H. & 32 others, , 2020, In: Cell. 180, 3, p. 568-584.e23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia
Monroe, T. O., Garrett, M. E., Kousi, M., Rodriguiz, R. M., Moon, S., Bai, Y., Brodar, S. C., Soldano, K. L., Savage, J., Hansen, T. F., Muzny, D. M., Gibbs, R. A., Barak, L., Sullivan, P. F., Ashley-Koch, A. E., Sawa, A., Wetsel, W. C., Werge, Thomas & Katsanis, N., 2020, In: Nature Communications. 11, 1, 14 p., 5903.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic prediction of school performance in individuals with and without psychiatric disorders
Rajagopal, V. M., Trajberg, B. B., Grove, J., Horsdal, H. T., Petersen, L., Bulik, C. M., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Hougaard, D. M., Mors, O., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Agerbo, E., Borglum, A. D., Demontis, D. & iPSYCH-Broad Consortium, I. C., 2020, In: Behavior Genetics. 50, 6, p. 476-477 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Polygenic risk and progression to bipolar or psychotic disorders among individuals diagnosed with unipolar depression in early life
Musliner, K. L., Krebs, M. D., Albiñana, C., Vilhjalmsson, B., Agerbo, E., Zandi, P. P., Hougaard, D. M., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Mortensen, P. B. & Østergaard, S. D., 2020, In: American Journal of Psychiatry. 177, 10, p. 936-943 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polygenic risk score, psychosocial environment and the risk of attention-deficit/hyperactivity disorder
Østergaard, S. D., Trabjerg, B. B., Als, T. D., Climent, C. A., Privé, F., Vilhjálmsson, B. J., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Demontis, D., Mortensen, P. B., Børglum, A. D., Mors, O. & Agerbo, E., 2020, In: Translational Psychiatry. 10, 1, 335.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genomics of the Viking world: [incl. correction]
Margaryan, A., Lawson, D. J., Sikora, M., Racimo, F., Rasmussen, S., Moltke, I., Cassidy, L. M., Jørsboe, E., Ingason, A., Pedersen, M. W., Korneliussen, T., Wilhelmson, H., Buś, M. M., de Barros Damgaard, P., Martiniano, R., Renaud, G., Bhérer, C., Moreno-Mayar, J. V., Fotakis, A. K., Allen, M. & 30 others, , 2020, In: Nature. 585, 7825, p. 390-396 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative genome-wide association analyses of receptive language in the Danish High Risk and Resilience Study
Nudel, R., Christiani, C. A. J., Ohland, J., Uddin, M. J., Hemager, N., Ellersgaard, D., Spang, K. S., Burton, B. K., Greve, A. N., Gantriis, D. L., Bybjerg-Grauholm, J., Jepsen, J. R. M., Thorup, Anne, Mors, O., Werge, Thomas & Nordentoft, Merete, 2020, In: BMC Neuroscience. 21, 14 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
Munn-Chernoff, M. A., Johnson, E. C., Chou, Y. L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S., Giusti-Rodríguez, P. & 332 others, , 2020, In: Addiction Biology (Online). 26, 1, 20 p., e12880.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Duffy-null genotype and risk of infection
Legge, S. E., Christensen, R. H., Petersen, L., Pardiñas, A. F., Bracher-Smith, M., Knapper, S., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Mortensen, P. B., Owen, M. J., O'Donovan, M. C., Benros, Michael Eriksen & Walters, J. T. R., 2020, In: Human Molecular Genetics. 29, 20, p. 3341-3349 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, , 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetic architecture of sporadic and multiple consecutive miscarriage
Laisk, T., Soares, A. L. G., Ferreira, T., Painter, J. N., Censin, J. C., Laber, S., Bacelis, J., Chen, C. Y., Lepamets, M., Lin, K., Liu, S., Millwood, I. Y., Ramu, A., Southcombe, J., Andersen, M. S., Yang, L., Becker, C. M., Børglum, A. D., Gordon, S. D., Bybjerg-Grauholm, J. & 35 others, , 2020, In: Nature Communications. 11, 5980.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome
Lahrouchi, N., Tadros, R., Crotti, L., Mizusawa, Y., Postema, P. G., Beekman, L., Walsh, R., Hasegawa, K., Barc, J., Ernsting, M., Turkowski, K. L., Mazzanti, A., Beckmann, B. M., Shimamoto, K., Diamant, U-B., Wijeyeratne, Y. D., Kucho, Y., Robyns, T., Ishikawa, T., Arbelo, E. & 86 others, , 2020, In: Circulation. 142, 4, p. 324-338Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Genetic risk scores for major psychiatric disorders and the risk of postpartum psychiatric disorders
Bauer, A. E., Liu, X., Byrne, E. M., Sullivan, P. F., Wray, N. R., Agerbo, E., Nyegaard, M., Grove, J., Musliner, K. L., Ingstrup, K. G., Johannsen, B. M. W., Mægbæk, M. L., Wang, Y., Nordentoft, M., Mors, O., Børglum, A. D., Werge, T., Hougaard, D. M., Mortensen, P. B., Munk-Olsen, T. & 1 others, , 11 Nov 2019, In: Translational Psychiatry. 9, 1, 13 p., 288.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Herpes Simplex Virus Type 1 infection is associated with suicidal behavior and first registered psychiatric diagnosis in a healthy population
Nissen, J., Trabjerg, B., Pedersen, M. G., Banasik, K., Pedersen, O. B., Sørensen, E., Nielsen, K. R., Erikstrup, C., Petersen, M. S., Paarup, H. M., Bruun-Rasmussen, P., Westergaard, D., Hansen, T. F., Pedersen, C. B., Werge, T., Torrey, F., Hjalgrim, H., Mortensen, P. B., Yolken, R., Brunak, S. & 2 others, , Oct 2019, In: Psychoneuroendocrinology. 108, p. 150-154Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration
Liu, X., Helenius, D., Skotte, L., Beaumont, R. N., Wielscher, M., Geller, F., Juodakis, J., Mahajan, A., Bradfield, J. P., Lin, F. T. J., Vogelezang, S., Bustamante, M., Ahluwalia, T. S., Pitkänen, N., Wang, C. A., Bacelis, J., Borges, M. C., Zhang, G., Bedell, B. A., Rossi, R. M. & 54 others, , 2 Sep 2019, In: Nature Communications. 10, 1, 13 p., 3927.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Anorexia Nervosa Genetics Initiative, A. N. G. I., Aug 2019, In: Nature Genetics. 51, 8, p. 1207-1214Research output: Contribution to journal › Letter › Research › peer-review
- Published
Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
GERAD1 Consortium:, G. C., Jul 2019, In: Nature Genetics. 51, 7, p. 1193 1 p.Research output: Contribution to journal › Comment/debate › Research
- Published
DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors
Hansen, T. F., Banasik, K., Erikstrup, C., Pedersen, O. B., Westergaard, D., Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, P., Andersen, S., Nyegaard, M., Jemec, G. B. E., Olesen, J., Werge, T., Johansson, P. I., Sørensen, E. & 3 others, , 9 Jun 2019, In: BMJ Open. 9, 6, p. 1-7 7 p., e028401.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 30 loci associated with bipolar disorder
eQTLGen Consortium, E. C., May 2019, In: Nature Genetics. 51, 5, p. 793-803Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variable DNA methylation in neonates mediates the association between prenatal smoking and birth weight
iPSYCH-Broad ASD Group, I. A. G., 15 Apr 2019, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 374, 1770, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment
Schork, A. J., Won, H., Appadurai, V., Nudel, R., Gandal, M., Delaneau, O., Revsbech Christiansen, M., Hougaard, D. M., Bækved-Hansen, M., Bybjerg-Grauholm, J., Giørtz Pedersen, M., Agerbo, E., Bøcker Pedersen, C., Neale, B. M., Daly, M. J., Wray, N. R., Nordentoft, M., Mors, O., Børglum, A. D., Bo Mortensen, P. & 4 others, , Mar 2019, In: Nature Neuroscience. 22, 3, p. 353-361Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of common genetic risk variants for autism spectrum disorder
Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, A. S. D. W. G. O. T. P. G. C., Mar 2019, In: Nature Genetics. 51, 3, p. 431-444Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
ADHD Working Group of the Psychiatric Genomics Consortium (PGC), A. W. G. O. T. P. G. C. (., Jan 2019, In: Nature Genetics. 51, 1, p. 63-75 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population
Nudel, R., Wang, Y., Appadurai, V., Schork, A. J., Buil, A., Agerbo, E., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Mors, O., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete, Thompson, W. K. & Benros, Michael Eriksen, 2019, In: Translational Psychiatry. 9, 1, 10 p., 283.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of bidirectional relationships between physical activity and depression among adults a 2-sample Mendelian randomization study
Choi, K. W., Chen, C. Y., Stein, M. B., Klimentidis, Y. C., Wang, M. J., Koenen, K. C., Smoller, J. W., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S. A., Bækvad-Hansen, M., Beekman, A. T. F. & 31 others, , 2019, In: JAMA Psychiatry. 76, 4, p. 399-408 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Childhood Exposure to Nitrogen Dioxide and Polygenic Risk Score for Schizophrenia With the Risk of Developing Schizophrenia
Horsdal, H. T., Agerbo, E., McGrath, J. J., Vilhjálmsson, B. J., Antonsen, S., Closter, A. M., Timmermann, A., Grove, J., Mok, P. L. H., Webb, R. T., Sabel, C. E., Hertel, O., Sigsgaard, T., Erikstrup, C., Hougaard, D. M., Werge, T., Nordentoft, M., Børglum, A. D., Mors, O., Mortensen, P. B. & 3 others, , 2019, In: JAMA Network Open. 2, 11, 12 p., e1914401.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia with Risk for Depression in the Danish Population
Musliner, K. L., Mortensen, P. B., McGrath, J. J., Suppli, N. P., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Andreassen, O., Pedersen, C. B., Pedersen, M. G., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Agerbo, E., 2019, In: JAMA Psychiatry. 76, 5, p. 516-525 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank
Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Mcintosh, A. M., Whalley, H. C., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J. & 216 others, , 2019, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 1, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants
Satterstrom, F. K., Walters, R. K., Singh, T., Wigdor, E. M., Lescai, F., Demontis, D., Kosmicki, J. A., Grove, J., Stevens, C., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Palmer, D. S., Maller, J. B., Nordentoft, M., Mors, O., Robinson, E. B., Hougaard, D. M., Werge, T. M., Bo Mortensen, P., Neale, B. M. & 3 others, , 2019, In: Nature Neuroscience. 22, 12, p. 1961-1965Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BIOLOGICAL PREDICTORS OF PSYCHIATRIC TRAJECTORIES IN A DANISH POPULATION COHORT OF INDIVIDUALS WITH SCHIZOPHRENIA
Krebs, M., Themudo, G. E., Benros, Michael Eriksen, Werge, Thomas & Thompson, W., 2019, In: European Neuropsychopharmacology. 29, S5, p. S260-S260 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Can Animal Models of Copy Number Variants That Predispose to Schizophrenia Elucidate Underlying Biology?
Forsingdal, A., Jørgensen, T. N., Olsen, L., Werge, Thomas, Didriksen, M. & Nielsen, J., 2019, In: Biological Psychiatry. 85, 1, p. 13-24 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Clinical association to FKBP5 rs1360780 in patients with depression
Dam, H., Buch, J. O. D., Nielsen, A. B., Weikop, Pia, Werge, Thomas & Jørgensen, M. B., 2019, In: Psychiatric Genetics. 29, 6, p. 220-225 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language
iPSYCH-Broad-PGC ADHD Consortium, I. A. C., 2019, In: Translational Psychiatry. 9, 1, 12 p., 35.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring Comorbidity Within Mental Disorders among a Danish National Population
Plana-Ripoll, O., Pedersen, C. B., Holtz, Y., Benros, M. E., Dalsgaard, S., De Jonge, P., Fan, C. C., Degenhardt, L., Ganna, A., Greve, A. N., Gunn, J., Iburg, K. M., Kessing, L. V., Lee, B. K., Lim, C. C. W., Mors, O., Nordentoft, M., Prior, A., Roest, A. M., Saha, S. & 12 others, , 2019, In: JAMA Psychiatry. 76, 3, p. 259-270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GENETIC SUBTYPES OF SCHIZOPHRENIA ELUCIDATED BY MULTISTATE DIAGNOSIS TRAJECTORIES
Themudo, G. E., Krebs, M., Benros, Michael Eriksen, Werge, Thomas & Thompson, W., 2019, p. 1338-1338.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C. B. D. W. G. O. T. P. G. C. S. W. G. O. T. P. G. C., Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C. M., 2019, In: American Journal of Psychiatry. 176, 8, p. 651-660Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, L. M., Dobbyn, A., Ruderfer, D. M., Hoffman, G., Wang, W., Pardiñas, A. F., Rajagopal, V. M., Als, T. D., T. Nguyen, H., Girdhar, K., Boocock, J., Roussos, P., Fromer, M., Kramer, R., Domenici, E., Gamazon, E. R., Purcell, S., CommonMind Consortium, The Schizophrenia Working Group of the PsyUniversity of Copenhagenchiatric Genomics Consortium, iPSYCH-GEMS Schizophrenia Working Group & 15 others, , 2019, In: Nature Genetics. 51, p. 659-674Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variants Associated with Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study
Meier, S. M., Trontti, K., Purves, K. L., Als, T. D., Grove, J., Laine, M., Pedersen, M. G., Bybjerg-Grauholm, J., Bækved-Hansen, M., Sokolowska, E., Mortensen, P. B., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Breen, G., Børglum, A. D., Eley, T. C., Hovatta, I., Mattheisen, M. & Mors, O., 2019, In: JAMA Psychiatry. 76, 9, p. 924-932 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study implicates CHRNA2 in cannabis use disorder
Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., Gudbjartsson, D. F., Pallesen, J., Hjorthøj, C., Reginsson, G. W., Tyrfingsson, T., Runarsdottir, V., Qvist, P., Christensen, J. H., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Huckins, L. M., Stahl, E. A., Timmermann, A., Agerbo, E. & 10 others, , 2019, In: Nature Neuroscience. 22, 7, p. 1066-1074Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Cell. 179, 7, p. 1469-1482 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomisk medicin som forbrugervare
Folkersen, L. & Werge, Thomas, 2019, In: Ugeskrift for Laeger. 181, 5 p., V11180789.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Disease Variation in the Light of Population Genomics
Prohaska, Ana, Racimo, Fernando, Schork, A. J., Sikora, Martin, Stern, A. J., Ilardo, M., Allentoft, Morten Erik, Folkersen, L., Buil, A., Moreno Mayar, J. Víctor, Korneliussen, Thorfinn Sand, Geschwind, D., Ingason, A., Werge, Thomas, Nielsen, Rasmus & Willerslev, Eske, 2019, In: Cell. 177, 1, p. 115-131 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Immunity and mental illness: findings from a Danish population-based immunogenetic study of seven psychiatric and neurodevelopmental disorders
Nudel, R., Benros, Michael Eriksen, Krebs, M. D., Allesøe, R. L., Lemvigh, C. K., Bybjerg-Grauholm, J., Børglum, A. D., Daly, M. J., Nordentoft, Merete, Mors, O., Hougaard, D. M., Mortensen, P. B., Buil, A., Werge, Thomas, Rasmussen, Simon & Thompson, W. K., 2019, In: European Journal of Human Genetics. 27, p. 1445-1455Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individuals with 22q11.2 deletion syndrome show intact prediction but reduced adaptation in responses to repeated sounds: Evidence from Bayesian mapping
Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Olsen, L., Didriksen, M., Baaré, W. F. C., Werge, Thomas, Garrido, M. I. & Siebner, Hartwig Roman, 2019, In: NeuroImage: Clinical. 22, 101721.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2019, In: Nature Communications. 10, 1, 18 p., 2548.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactive effects between hemizygous 15q13.3 microdeletion and peripubertal stress on adult behavioral functions
Giovanoli, S., Werge, Thomas, Mortensen, P. B., Didriksen, M. & Meyer, U., 2019, In: Neuropsychopharmacology. 44, 4, p. 703-710 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
Nievergelt, C. M., Maihofer, A. X., Klengel, T., Atkinson, E. G., Chen, C-Y., Choi, K. W., Coleman, J. R. I., Dalvie, S., Duncan, L. E., Gelernter, J., Levey, D. F., Logue, M. W., Polimanti, R., Provost, A. C., Ratanatharathorn, A., Stein, M. B., Torres, K., Aiello, A. E., Almli, L. M., Amstadter, A. B. & 159 others, , 2019, In: Nature Communications. 10, 1, 4558.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Burgdorf, K. S., Trabjerg, B., Giørtz Pedersen, M., Nissen, J., Banasik, K., Birger Pedersen, O., Sørensen, E., René Nielsen, K., Hørup Larsen, M., Erikstrup, C., Bruun-Rasmussen, P., Westergaard, D., Wegner Thørner, L., Hjalgrim, H., Martina Paarup, H., Brunak, S., Pedersen, C. B., Fuller Torrey, E., Werge, T., Bo Mortensen, P. & 2 others, , 2019, In: Brain, Behavior, and Immunity. 79, p. 152-158Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Migraine polygenic risk score associates with efficacy of migraine-specific drugs
Kogelman, L. J. A., Esserlind, A-L., Christensen, A. F., Awasthi, S., Ripke, S., Ingason, A., Davidsson, O. B., Erikstrup, C., Hjalgrim, H., Ullum, H., Olesen, J., Hansen, T. F., Gudbjartsson, D., Gastafsson, O., Stefansson, K., Stefansson, H., Porsteinsdottir, U., Andersen, S., Banasik, K., Brunak, S. & 73 others, , 2019, In: Neurology: Genetics. 5, 6, 12 p., e364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A. & 32 others, , 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations
Wang, Y., Karstoft, Karen-Inge, Nievergelt, C. M., Maihofer, A. X., Stein, M. B., Ursano, R. J., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Andreassen, O. A., Werge, Thomas, Thompson, W. K. & Andersen, S. B., 2019, In: Journal of Affective Disorders. 252, p. 350-357 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders
Skogstrand, K., Hagen, C. M., Borbye-Lorenzen, N., Christiansen, M., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Werge, Thomas, Borglum, A., Mors, O., Nordentoft, M., Mortensen, P. B. & Hougaard, D. M., 2019, In: Translational Psychiatry. 9, 9 p., 252.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roadmap for a precision-medicine initiative in the Nordic region
Njølstad, P. R., Andreassen, O. A., Brunak, S., Børglum, A. D., Dillner, J., Esko, T., Franks, P. W., Freimer, N., Groop, L., Heimer, H., Hougaard, D. M., Hovig, E., Hveem, K., Jalanko, A., Kaprio, J., Knudsen, G. P., Melbye, M., Metspalu, A., Mortensen, P. B., Palmgren, J. & 11 others, , 2019, In: Nature Genetics. 51, p. 924-930Research output: Contribution to journal › Comment/debate › Research
- Published
Schizophrenia polygenic risk scores, urbanicity and treatment-resistant schizophrenia
Gasse, C., Wimberley, T., Wang, Y., Mors, O., Børglum, A., Als, T. D., Werge, Thomas, Nordentoft, Merete, Hougaard, D. M. & Horsdal, H. T., 2019, In: Schizophrenia Research. 212, p. 79-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Complex spatio-temporal distribution and genomic ancestry of mitochondrial DNA haplogroups in 24,216 Danes
Bybjerg-Grauholm, J., Hagen, C. M., Gonçalves, V. F., Bækvad-Hansen, M., Hansen, C. S., Hedley, P. L., Kanters, Jørgen K., Nielsen, J., Theisen, M., Mors, O., Kennedy, J., Als, T. D., Demur, A. B., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 13 Dec 2018, In: PLoS ONE. 13, 12, 26 p., e0208829.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Schizophrenia-associated mt-DNA SNPs exhibit highly variable haplogroup affiliation and nuclear ancestry: Bi-genomic dependence raises major concerns for link to disease
Hagen, C. M., Gonçalves, V. F., Hedley, P. L., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hansen, C. S., Kanters, Jørgen K., Nielsen, J., Mors, O., Demur, A. B., Als, T. D., Nordentoft, Merete, Børglum, A., Mortensen, P. B., Kennedy, J., Werge, Thomas, Hougaard, D. M. & Christiansen, M., 1 Dec 2018, In: PLoS ONE. 13, 12, 14 p., e0208828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk
International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu, I. M. S. G. C. E. A. C. C. E., Sellebjerg, Finn Thorup, Ullum, H. & Werge, Thomas, 29 Nov 2018, In: Cell. 175, 6, p. 1679-1687.e7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Socio-demographic characteristics of adults with self-reported ADHD symptoms in a Danishpopulation of 12,415 blood donors
Høffding, L. K. E., Nielsen, Maria Haahr, Didriksen, Maria, Schow, T., Werge, Thomas, Nielsen, K. R., Erikstrup, C., Pedersen, O. B., Hjalgrim, H., Jepsen, J. R. M., Hansen, T. F., Banasik, K., Ullum, H. & Burgdorf, K., 20 Aug 2018, In: Journal of Psychiatry and Behavioral Sciences. 3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder
Martin, J., Walters, R. K., Demontis, D., Mattheisen, M., Lee, S. H., Robinson, E., Brikell, I., Ghirardi, L., Larsson, H., Lichtenstein, P., Eriksson, N., 23andMe Research Team, 2. R. T., Psychiatric Genomics Consortium: ADHD Subgroup, P. G. C. A. S., iPSYCH–Broad ADHD Workgroup, I. A. W., Werge, Thomas & Nordentoft, Merete, 15 Jun 2018, In: Biological Psychiatry. 83, 12, p. 1044-1053 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restless legs syndrome is associated with major comorbidities in a population of Danish blood donors
Didriksen, Maria, Allen, R. P., Burchell, B. J., Thørner, L. W., Rigas, A. S., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nielsen, K., Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., May 2018, In: Sleep Medicine. 45, p. 124-131 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated polygenic burden for autism is associated with differential DNA methylation at birth
Hannon, E., Schendel, D., Ladd-Acosta, C., Grove, J., Hansen, C. S., Andrews, S. V., Hougaard, D. M., Bresnahan, M., Mors, O., Hollegaard, M. V., Bækvad-Hansen, M., Hornig, M., Mortensen, P. B., Børglum, A. D., Werge, T., Pedersen, M. G., Nordentoft, M., Buxbaum, J., Fallin, M. D., Bybjerg-Grauholm, J. & 2 others, , 28 Mar 2018, In: Genome Medicine. 10, 13 p., 19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heritability of Schizophrenia and Schizophrenia Spectrum Based on the Nationwide Danish Twin Register
Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 15 Mar 2018, In: Biological Psychiatry. 83, 6, p. 492-498Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
Haney, J. R., CommonMind Consortium, C. C., PsychENCODE Consortium, P. C. & iPSYCH-BROAD Working Group, I. W. G., 9 Feb 2018, In: Science. 359, 6376, p. 693-697 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response
Larsen, K. M., Pellegrino, G., Birknow, M. R., Kjær, T. N., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Mørup, M. & Siebner, Hartwig Roman, 2018, In: Schizophrenia Bulletin. 44, 2, p. 388–397Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
Nagy, S., Maurer, G. W., Hentze, J. L., Rose, M., Werge, Thomas & Rewitz, Kim, 2018, In: PLOS Genetics. 14, 12, e1007623.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties
St Pourcain, B., Robinson, E. B., Anttila, V., Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., Zammit, S., Fisher, S. E., Neale, B. M., Anney, R. J. L., Ripke, S., Hollegaard, M. V., Werge, T., iPSYCH-SSI-Broad Autism Group, Ronald, A., Grove, J., Hougaard, D. M. & 4 others, , 2018, In: Molecular Psychiatry. 23, 2, p. 263-270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age at first birth in women is genetically associated with increased risk of schizophrenia
Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, , 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome
Larsen, K. M., Mørup, M., Birknow, M. R., Fischer, E., Hulme, O., Vangkilde, A., Schmock, H., Baaré, W. F. C., Didriksen, M., Olsen, L., Werge, Thomas, Siebner, Hartwig Roman & Garrido, M. I., 2018, In: Schizophrenia Research. 197, p. 328-336Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of shared heritability in common disorders of the brain
Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 557 others, , 2018, In: Science. 360, 6395, 40 p., eaap8757.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient genomes from Iceland reveal the making of a human population
Ebenesersdóttir, S. S., Sandoval Velasco, M., Gunnarsdóttir, E. D., Jagadeesan, A., Guðmundsdóttir, V. B., Thordardóttir, E. L., Einarsdóttir, M. S., Moore, K. H. S., Sigurðsson, Á., Magnusdóttir, D. N., Jonsson, H., Snorradóttir, S., Hovig, E., Møller, P., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T., Cavalleri, G. L. & 10 others, , 2018, In: Science. 360, 6392, p. 1028-1032 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brief Report: Clusters and Trajectories Across the Autism and/or ADHD Spectrum
LaBianca, S., Pagsberg, Anne Katrine, Jakobsen, K. D., Demur, A. B., Bartalan, M., LaBianca, J. & Werge, Thomas, 2018, In: Journal of Autism and Developmental Disorders. 48, 10, p. 3629-3636 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Pardiñas, A. F., Holmans, P., Pocklington, A. J., Escott-Price, V., Ripke, S., Carrera, N., Legge, S. E., Bishop, S., Cameron, D., Hamshere, M. L., Han, J., Hubbard, L., Lynham, A., Mantripragada, K., Rees, E., MacCabe, J. H., McCarroll, S. A., Baune, B. T., Breen, G., Byrne, E. M. & 51 others, , 2018, In: Nature Genetics. 50, p. 381-389Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comorbidity of migraine with ADHD in adults
Hansen, Thomas Folkmann, Hoeffding, L. K., Kogelman, L., Haspang, T. M., Ullum, H., Sørensen, E., Erikstrup, C., Pedersen, O. B., Nielsen, K. R., Hjalgrim, H., Paarup, H. M., Werge, Thomas & Burgdorf, K., 2018, In: BMC Neurology. 18, 1, p. 1-9 147.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
Hughes, T., Sønderby, I. E., Polushina, T., Hansson, L., Holmgren, A., Athanasiu, L., Melbø-Jørgensen, C., Hassani, S., Hoeffding, L. K., Herms, S., Bergen, S. E., Karlsson, R., Song, J., Rietschel, M., Nöthen, M. M., Forstner, A. J., Hoffmann, P., Hultman, C. M., Landén, M., Cichon, S. & 4 others, , 2018, In: Translational Psychiatry. 8, 1, p. 1-12 210.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GENOME-WIDE ASSOCIATION STUDY, HERITABILITY ESTIMATION AND POLYGENIC RISK ANALYSIS OF SUSCEPTIBILITY TO INFECTIONS IN 65,534 INDIVIDUALS WITH SEVERE MENTAL DISORDERS AND POPULATION CONTROLS. O4.6.
Benros, Michael Eriksen, Nudel, R., Wang, Y., Appadurai, V., Schork, A., Agerbo, E., Werge, Thomas, Nordentoft, Merete, Mortensen, P., Buil, A. & Thompson, W., 2018, In: Schizophrenia Bulletin. 44, Suppl. 1, p. S85 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis
Velthorst, E., Froudist-Walsh, S., Stahl, E., Ruderfer, D., Ivanov, I., Buxbaum, J., iPSYCH-Broad ASD Group, the IMAGEN consortium, Banaschewski, T., Bokde, A. L. W., Bromberg, U., Büchel, C., Burke Quinlan, E., Desrivières, S., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Paillère Martinot, M. L. & 31 others, , 2018, In: Translational Psychiatry. 8, 1, 204.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Lu, Y., Pouget, J. G., Andreassen, O. A., Djurovic, S., Esko, T., Hultman, C. M., Metspalu, A., Milani, L., Werge, Thomas & Sullivan, P. F., 2018, In: Psychological Medicine. 48, 7, p. 1201-1208 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, T. M. D. D. W. G. O. T. P. G. C., 2018, In: Nature Genetics. 50, 5, p. 668-681 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder
Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C., Thomson, P. A., Porteous, D., Campbell, A., Smith, B. H., Black, C., Padmanabhan, S., McIntosh, A. M., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Agerbo, E., Air, T. M. & 32 others, , 2018, In: PLOS ONE. 13, 12, p. 1-29 e0209160.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of rearrangements in the 22q11.2 region and population-based risk of neuropsychiatric and developmental disorders in a Danish population: a case-cohort study
Olsen, L., Sparsø, T., Weinsheimer, S. M., Dos Santos, M. B. Q., Mazin, W., Rosengren, A., Sanchez, X. C., Hoeffding, L. K., Schmock, H., Baekvad-Hansen, M., Bybjerg-Grauholm, J., Daly, M. J., Neale, B. M., Pedersen, M. G., Agerbo, E., Mors, O., Børglum, A., Nordentoft, M., Hougaard, D. M., Mortensen, P. B. & 4 others, , 2018, In: The Lancet Psychiatry. 5, 7, p. 573-580 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum
Ganna, A., Satterstrom, F. K., Zekavat, S. M., Das, I., Kurki, M. I., Churchhouse, C., Alfoldi, J., Martin, A. R., Havulinna, A. S., Byrnes, A., Thompson, W. K., Nielsen, P. R., Karczewski, K. J., Saarentaus, E., Rivas, M. A., Gupta, N., Pietiläinen, O., Emdin, C. A., Lescai, F., Bybjerg-Grauholm, J. & 28 others, , 2018, In: American Journal of Human Genetics. 102, 6, p. 1204-1211Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia
Fan, C. C., McGrath, J. J., Appadurai, V., Buil, A., Gandal, M. J., Schork, A. J., Mortensen, P. B., Agerbo, E., Geschwind, S. A., Geschwind, D., Werge, Thomas, Thompson, W. K. & Pedersen, C. B., 2018, In: Nature Communications. 9, 7 p., 5296.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods
Thornton, L. M., Munn-Chernoff, M. A., Baker, J. H., Juréus, A., Parker, R., Henders, A. K., Larsen, J. T., Petersen, L., Watson, H. J., Yilmaz, Z., Kirk, K. M., Gordon, S., Leppä, V. M., Martin, F. C., Whiteman, D. C., Olsen, C. M., Werge, T. M., Pedersen, N. L., Kaye, W., Bergen, A. W. & 26 others, , 2018, In: Contemporary Clinical Trials. 74, p. 61-69 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders
Pedersen, C. B., Bybjerg-Grauholm, J., Pedersen, M. G., Grove, J., Agerbo, E., Bækvad-Hansen, M., Poulsen, J. B., Hansen, C. S., McGrath, J. J., Als, T. D., Goldstein, J. I., Neale, B. M., Daly, M. J., Hougaard, D. M., Mors, O., Nordentoft, Merete, Børglum, A. D., Werge, Thomas & Mortensen, P. B., 2018, In: Molecular Psychiatry. 23, p. 6-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations
Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A. & 31 others, , Dec 2017, In: JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission
Nielsen, J., Fejgin, K., Sotty, F., Nielsen, V., Mørk, A., Christoffersen, C. T., Yavich, L., Lauridsen, J. B., Clausen, D., Larsen, P. H., Egebjerg, J., Werge, Thomas, Kallunki, P., Christensen, K. V. & Didriksen, M., 30 Nov 2017, In: Translational Psychiatry. 7, 12 p., 1261.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome
Starnawska, A., Hansen, C. S., Sparsø, T., Mazin, W., Olsen, L., Bertalan, M., Buil, A., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mortensen, P. B., Pedersen, C. B., Nyegaard, M., Werge, Thomas & Weinsheimer, S., 29 Aug 2017, In: Translational Psychiatry. 7, 11 p., e1221.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of restless legs syndrome and associated factors in an otherwise healthy population: results from the Danish Blood Donor Study
Didriksen, M., Rigas, A. S., Allen, R. P., Burchell, B. J., Di Angelantonio, E., Nielsen, Maria Haahr, Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, Ole Birger Vesterager, Bruun, M. T., Burgdorf, K. S., Sørensen, E. & Ullum, H., Aug 2017, In: Sleep Medicine. 36, p. 55-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quetiapine extended release versus aripiprazole in children and adolescents with first-episode psychosis: the multicentre, double-blind, randomised tolerability and efficacy of antipsychotics (TEA) trial
Pagsberg, A. K., Jeppesen, P., Klauber, D. G., Jensen, K. G., Ruda, D., Stentebjerg-Olesen, M., Jantzen, P., Rasmussen, S., Saldeen, E. A-S., Lauritsen, M-B. G., Bilenberg, N., Stenstrom, A. D., Nyvang, L., Madsen, S., Werge, T. M., Lange, T., Gluud, C., Skoog, M., Winkel, P., Jepsen, J. R. M. & 3 others, , Aug 2017, In: The Lancet Psychiatry. 4, 8, p. 605-618Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lessons to be learned from 22q2.11 syndromes: reply
Hoeffding, L. K., Pedersen, C. B. & Werge, Thomas, Jul 2017, In: JAMA Psychiatry. 74, 7, p. 757-758 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
Weiner, D. J., Wigdor, E. M., Ripke, S., Walters, R. K., Kosmicki, J. A., Grove, J., Samocha, K. E., Goldstein, J. I., Okbay, A., Bybjerg-Grauholm, J., Werge, T., Hougaard, D. M., Taylor, J., Skuse, D., Devlin, B., Anney, R., Sanders, S. J., Bishop, S., Mortensen, P. B., Børglum, A. D. & 32 others, , Jul 2017, In: Nature Genetics. 49, 7, p. 978-985 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism
Sapkota, Y., Steinthorsdottir, V., Morris, A. P., Fassbender, A., Rahmioglu, N., De Vivo, I., Buring, J. E., Zhang, F., Edwards, T. L., Jones, S., Dorien, O., Peterse, D., Rexrode, K. M., Ridker, P. M., Schork, A. J., MacGregor, S., Martin, N. G., Becker, C. M., Adachi, S., Yoshihara, K. & 23 others, , 24 May 2017, In: Nature Communications. 8, 12 p., 15539.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Anney, R. J. L., Ripke, S., Anttila, V., Grove, J., Holmans, P., Huang, H., Klei, L., Lee, P. H., Medland, S. E., Neale, B., Robinson, E., Weiss, L. A., Zwaigenbaum, L., Yu, T. W., Wittemeyer, K., Willsey, A. J., Wijsman, E. M., Werge, T., Wassink, T. H., Waltes, R. & 143 others, , 22 May 2017, In: Molecular Autism. 8, 17 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register
Hilker, Rikke Warming, Helenius, D., Fagerlund, Birgitte, Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, Apr 2017, In: EBioMedicine. 18, p. 320-326Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk of psychiatric disorders among individuals with the 22q11.2 deletion or duplication: A Danish nationwide, register-based study
Hoeffding, L. K., Trabjerg, B. B., Olsen, L., Mazin, W., Sparsø, T., Vangkilde, A., Mortensen, P. B., Pedersen, C. B. & Werge, Thomas, 1 Mar 2017, In: JAMA Psychiatry. 74, 3, p. 282-290 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nomenclature for alleles of the human carboxylesterase 1 gene
INDICES Consortium, I. C., 1 Jan 2017, In: Pharmacogenetics and Genomics. 27, 2, p. 78-80 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry
Schork, A. J., iPSYCH-SSI-Broad Group, I. G. & Werge, Thomas, 2017, In: Scientific Reports. 7, 11 p., 11380.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits
Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C. & 86 others, , 2017, In: Nature Communications. 8, 11 p., 744.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comorbidities to restless legs syndrome – results from the Danish blood donor study
Didriksen, Maria, Hansen, T., Rigas, A., Allen, R., Burchell, B., Thørner, L., Nielsen, K., Di Angelantonio, E., Nielsen, M., Jennum, Poul, Werge, Thomas, Erikstrup, C., Pedersen, O., Paarup, H., Hjalgrim, H., Bruun, M., Burgdorf, K., Sørensen, E. & Ullum, H., 2017, In: Sleep Medicine. 40, Supplement 1, p. E79 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., Gujral, M., Brandler, W. M., Malhotra, D., Wang, Z., Fuentes Fajarado, K. V., Maile, M. S., Ripke, S., Agartz, I., Albus, M., Alexander, M. & 34 others, , 2017, In: Nature Genetics. 49, 1, p. 27-35Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of shared genetic susceptibility loci between autoimmune diseases and schizophrenia based on genome-wide association studies
Hoeffding, L. K. E., Rosengren, A., Thygesen, J. H., Schmock, H., Werge, Thomas & Hansen, T., 2017, In: Nordic Journal of Psychiatry. 71, 1, p. 20-25 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C. & 31 others, , 2017, In: Nature Communications. 8, 14774.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
Joshi, P. K., Pirastu, N., Kentistou, K. A., Fischer, K., Hofer, E., Schraut, K. E., Clark, D. W., Nutile, T., Barnes, C. L. K., Timmers, P. R. H. J., Shen, X., Gandin, I., McDaid, A. F., Hansen, T. F., Gordon, S. D., Giulianini, F., Boutin, T. S., Abdellaoui, A., Zhao, W., Medina-Gomez, C. & 34 others, , 2017, In: Nature Communications. 8, 13 p., 910.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
Le Hellard, S., Wang, Y., Witoelar, A., Zuber, V., Bettella, F., Hugdahl, K., Espeseth, T., Steen, V. M., Melle, I., Desikan, R., Schork, A. J., Thompson, W. K., Dale, A. M., Djurovic, S., Andreassen, O. A., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Ripke, S., Neale, B. M., Corvin, A., Pers, T. H. & 11 others, , 2017, In: Schizophrenia Bulletin. 43, 3, p. 654-664Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility?
Hilker, R., Helenius, D., Fagerlund, B., Skytthe, A., Christensen, K., Werge, Thomas, Nordentoft, Merete & Glenthøj, Birte Yding, 2017, In: EBioMedicine. 18, p. 320-326Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: A study in male mice
Didriksen, M., Fejgin, K., Nilsson, S. R. O., Birknow, M. R., Grayton, H. M., Larsen, P. H., Lauridsen, J. B., Nielsen, V., Celada, P., Santana, N., Kallunki, P., Christensen, K. V., Werge, Thomas, Stensbøl, T. B., Egebjerg, J., Gastambide, F., Artigas, F., Bastlund, J. F. & Nielsen, J., 2017, In: Journal of Psychiatry and Neuroscience. 42, 1, p. 48-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe Parkinsonism and Creatine Kinase Increase After Low-Dose Aripiprazole Treatment in a Patient of African Descent
Jørgensen, A., Thorleifsson, A., Jimenez-Solem, E., Werge, Thomas & Rasmussen, H. B., 2017, In: Journal of Clinical Psychopharmacology. 37, 5, p. 630-631Research output: Contribution to journal › Letter › Research › peer-review
- Published
The catechol-O-methyltransferase (COMT) Val158Met genotype modulates working memory-related dorsolateral prefrontal response and performance in bipolar disorder
Miskowiak, K. W., Kjærstad, H. L., Støttrup, M. M., Svendsen, A. M., Demant, K. M., Hoeffding, L. K., Werge, Thomas, Burdick, K. E., Domschke, K., Carvalho, A. F., Vieta, E., Vinberg, Maj, Kessing, Lars Vedel, Siebner, Hartwig Roman & Macoveanu, J., 2017, In: Bipolar Disorders. 19, 3, p. 214-224 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Investigation of SNP rs2060546 Immediately Upstream to NTN4 in a Danish Gilles de la Tourette Syndrome Cohort
Padmanabhuni, S. S., Houssari, R., Esserlind, A., Olesen, Jes, Werge, Thomas, Hansen, T. F., Bertelsen, B., Tsetsos, F., Paschou, P. & Tümer, Asuman Zeynep, Nov 2016, In: Frontiers in Neuroscience. 10, 7 p., 531.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study
Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A. D., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D. W., Mowry, B. J., Müller-Mhysok, B., Neale, B. M. & 297 others, , Oct 2016, In: PLOS Genetics. 12, 10, 20 p., e1006343.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of COMT Val158Met genotype on neural response and performance during spatial working memory in remitted patients with bipolar disorder
Miskowiak, Kamilla, Kjærstad, H. L., Støttrup, M. M., Vinberg, Maj, Carvalho, A. F., Vieta, E., Høffding, L. K., Werge, Thomas, Kessing, Lars Vedel & Macoveanu, J., Oct 2016, In: European Neuropsychopharmacology. 26, Supplement 2, p. S440-S440 1 p., P.2.d.035.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genetic Markers of Human Evolution Are Enriched in Schizophrenia
Srinivasan, S., Bettella, F., Mattingsdal, M., Wang, Y., Witoelar, A., Schork, A. J., Thompson, W. K., Zuber, V., Winsvold, B. S., Zwart, J., Collier, D. A., Desikan, R. S., Melle, I., Werge, Thomas, Dale, A. M., Djurovic, S., Andreassen, O. A. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium, S. W. G. O. T. P. G. C. T. I. H. G. C., 15 Aug 2016, In: Biological Psychiatry. 80, 4, p. 284-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H. & 31 others, , Aug 2016, In: Nature Genetics. 48, 8, p. 856-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Digital questionnaire platform in the Danish Blood Donor Study
Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of genetic constitution on migraine drug responses
Christensen, A. F., Esserlind, A., Werge, Thomas, Stefánsson, H., Stefánsson, K. & Olesen, Jes, Jun 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 624-39 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders
Isles, A. R., Ingason, A., Lowther, C., Walters, J. T. R., Gawlick, M., Stöber, G., Rees, E., Martin, J., Little, R. B., Potter, H., Georgieva, L., Pizzo, L., Ozaki, N., Aleksic, B., Kushima, I., Ikeda, M., Iwata, N., Levinson, D. F., Gejman, P. V., Shi, J. & 20 others, , May 2016, In: P L o S Genetics. 12, 5, e1005993.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Schizophrenia Spectrum Disorders in a Danish 22q11.2 Deletion Syndrome Cohort Compared to the Total Danish Population—A Nationwide Register Study
Vangkilde, A., Olsen, L., Hoeffding, L. K. E., Pedersen, C. B., Mortensen, P. B., Werge, Thomas & Trabjerg, B., May 2016, In: Schizophrenia Bulletin. 42, 3, p. 824-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of AADAC Deletion and Gilles de la Tourette Syndrome in a Large European Cohort
Bertelsen, B., Stefánsson, H., Riff Jensen, L., Melchior, L., Debes, N. M., Groth, C., Skov, L., Werge, T., Karagiannidis, I., Tarnok, Z., Barta, C., Nagy, P., Farkas, L., Brøndum-Nielsen, K., Rizzo, R., Gulisano, M., Rujescu, D., Kiemeney, L. A., Tosato, S., Nawaz, M. S. & 14 others, , 1 Mar 2016, In: Biological Psychiatry. 79, 5, p. 383–391 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
15q13.3 homozygous knockout mouse model display epilepsy-, autism- and schizophrenia-related phenotypes
Forsingdal, A., Fejgin, K., Nielsen, V., Werge, Thomas & Nielsen, J., 2016, In: Translational Psychiatry. 6, 7, p. 1-9 9 p., e860.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An epigenetic clock for gestational age at birth based on blood methylation data
Knight, A. K., Craig, J. M., Theda, C., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Hollegaard, M. V., Hougaard, D. M., Mortensen, P. B., Weinsheimer, S. M., Werge, T. M., Brennan, P. A., Cubells, J. F., Newport, D. J., Stowe, Z. N., Cheong, J. L. Y., Dalach, P., Doyle, L. W., Loke, Y. J., Baccarelli, A. A. & 27 others, , 2016, In: Genome Biology (Online Edition). 17, 11 p., 206.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome
Vangkilde, A., Jepsen, J. M. R., Schmock, H., Olesen, C., Arnarsdóttir, S., Baaré, W. F. C., Plessen, K. J., Didriksen, M., Siebner, Hartwig Roman, Werge, Thomas & Olsen, L., 2016, In: Journal of Neurodevelopmental Disorders. 8, 13 p., 42.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics
Holland, D., Wang, Y., Thompson, W. K., Schork, A. J., Chen, C., Lo, M., Witoelar, A., Werge, Thomas, O'Donovan, M. C., Andreassen, O. A., Dale, A. M. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 2016, In: Frontiers in Genetics. 7, 13 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women
Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., LifeLines Cohort Study, L. C. S., TwinsUK, T. & Werge, Thomas, 2016, In: J A M A Psychiatry. 73, 5, p. 497-505 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
Robinson, E. B., St Pourcain, B., Anttila, V., Kosmicki, J. A., Bulik-Sullivan, B., Grove, J., Maller, J., Samocha, K. E., Sanders, J-S. F., Ripke, S., Martin, J., Hollegaard, M. V., Werge, T., Hougaard, D. M., Neale, B. M., Evans, D. M., Skuse, D., Mortensen, P. B., Børglum, A. D., Ronald, A. & 3 others, , 2016, In: Nature Genetics. 48, 5, p. 552-5 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness
Bigdeli, T. B., Ripke, S., Bacanu, S-A., Lee, S. H., Wray, N. R., Gejman, P. V., Rietschel, M., Cichon, S., St Clair, D., Corvin, A., Kirov, G., McQuillin, A., Gurling, H., Rujescu, D., Andreassen, O. A., Werge, T., Blackwood, D. H. R., Pato, C. N., Pato, M. T., Malhotra, A. K. & 4 others, , 2016, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 171, 2, p. 276-289 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High loading of polygenic risk in cases with chronic schizophrenia
Meier, S. M., Agerbo, E., Maier, R., Pedersen, C. B., Lang, M., Grove, J., Hollegaard, M. V., Demontis, D., Trabjerg, B. B., Hjorthøj, C., Ripke, S., Degenhardt, F., Nöthen, M. M., Rujescu, D., Maier, W., Werge, T., Mors, O., Hougaard, D. M., Børglum, A. D., Wray, N. R. & 5 others, , 2016, In: Molecular Psychiatry. 21, p. 969-974Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA
Poulsen, J. B., Lescai, F., Grove, J., Bækvad-Hansen, M., Christiansen, M., Hagen, C. M., Maller, J., Stevens, C., Li, S., Li, Q., Sun, J., Wang, J., Nordentoft, Merete, Werge, Thomas, Mortensen, P. B., Børglum, A. D., Daly, M., Hougaard, D. M., Bybjerg-Grauholm, J. & Hollegaard, M. V., 2016, In: P L o S One. 11, 4, 13 p., e0153253.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of rare high-risk copy number variants affecting the dopamine transporter gene in mental disorders
Hoeffding, L. K. E., Duong, L. T. T., Ingason, A., Rosengren, A., Sorbanski, E., Witt, S. H., Djurovic, S., Andreassen, O. A., Hansen, T., Werge, Thomas & Rasmussen, Henrik Berg, 2016, In: Nordic Journal of Psychiatry. 70, 4, p. 276-279 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS
Wang, Y., Thompson, W. K., Schork, A. J., Holland, D., Chen, C-H., Bettella, F., Desikan, R. S., Li, W., Witoelar, A., Zuber, V., Devor, A., Nöthen, M. M., Rietschel, M., Chen, Q., Werge, T., Cichon, S., Weinberger, D. R., Djurovic, S., O'Donovan, M. C., Visscher, P. M. & 2 others, , 2016, In: P L o S Genetics. 12, 1, 22 p., e1005803.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample
Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies
Thompson, W. K., Wang, Y., Schork, A. J., Witoelar, A., Zuber, V., Xu, S., Werge, Thomas, Holland, D., Andreassen, O. A. & Dale, A. M., 29 Dec 2015, In: P L o S Genetics. 11, 12, p. 1-21 21 p., e1005717.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association Study of CHRNA7 Promoter Variants with Sensory and Sensorimotor Gating in Schizophrenia Patients and Healthy Controls: A Danish Case-Control Study
Bertelsen, B., Oranje, B., Melchior, L., Fagerlund, Birgitte, Werge, Thomas, Mikkelsen, Jens D., Tümer, Asuman Zeynep & Glenthøj, Birte Yding, Dec 2015, In: NeuroMolecular Medicine. 17, 4, p. 423-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linkage and whole genome sequencing identify a locus on 6q25-26 for formal thought disorder and implicate MEF2A regulation
Thygesen, J. H., Zambach, S. K., Ingason, A., Lundin, P., Hansen, T., Bertalan, M., Rosengren, A., Bjerre, D., Ferrero-Miliani, L., Rasmussen, Henrik Berg, Parnas, Josef & Werge, Thomas, Dec 2015, In: Schizophrenia Research. 169, 1-3, p. 441-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family
Duong, L. T. T., Hoeffding, L. K., Petersen, K. B., Knudsen, C. D., Thygesen, J. H., Klitten, L. L., Tommerup, Niels, Ingason, A. & Werge, Thomas, Dec 2015, In: European Journal of Medical Genetics. 58, 12, p. 650-653 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genetic differentiation of height and body mass index across Europe
Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., Powell, J. E., Vinkhuyzen, A., Berndt, S. I., Gustafsson, S., Justice, A. E., Kahali, B., Locke, A. E., Pers, T. H., Vedantam, S., Wood, A. R., van Rheenen, W., Andreassen, O. A., Gasparini, P., Metspalu, A. & 23 others, , Nov 2015, In: Nature Genetics. 47, 11, p. 1357-62, 2 unpag. Methods 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics
Rasmussen, Henrik Berg, Bjerre, D., Linnet, Kristian, Jürgens, G., Dalhoff, Kim, Stefansson, H., Hankemeier, T., Kaddurah-Daouk, R., Taboureau, O., Brunak, Søren, Houmann, T., Jeppesen, Pia, Pagsberg, Anne Katrine, Plessen, K., Dyrborg, J., Hansen, Peter Riis, Hansen, P. E., Hughes, T., Werge, Thomas & INDICES Consortium, I. C., Apr 2015, In: Pharmacogenomics. 16, 6, p. 649-65Research output: Contribution to journal › Review › Research › peer-review
- Published
Usefulness of the SNP microarray technology to identify rare mutations in the case of perinatal death
Hoeffding, L. K., Kock, K. F., Johnsen, I. G., Hansen, Thomas Folkmann & Werge, Thomas, Jan 2015, In: Case Reports in Perinatal Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates
Andersen, M. B., Croy, C. H., Dencker, D., Werge, Thomas, Bymaster, F. P., Felder, C. C. & Fink-Jensen, Anders, 2015, In: PLOS ONE. 10, 4, p. 1-13 13 p., e0122722.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combinations of Genetic Data Present in Bipolar Patients, but Absent in Control Persons
Mellerup, Erling Thyge, Andreassen, O. A., Bennike, B., Dam, H., Djurovic, S., Hansen, T., Jørgensen, Martin Balslev, Kessing, Lars Vedel, Koefoed, P., Melle, I., Mors, O., Werge, Thomas & Moeller, G. L., 2015, In: P L o S One. 10, 11, 7 p., e0143432.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating historical candidate genes for schizophrenia
Farrell, M. S., Werge, Thomas, Sklar, P., Owen, M. J., Ophoff, R. A., O'Donovan, M. C., Corvin, A., Cichon, S. & Sullivan, P. F., 2015, In: Molecular Psychiatry. 20, p. 555-62 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Soluble Urokinase-Type Plasminogen Activator Receptor Levels in Patients With Schizophrenia
Nielsen, J., Røge, R., Pristed, S. G., Viuff, A. G., Ullum, H., Thørner, L. W., Werge, Thomas & Vang, T., 2015, In: Schizophrenia Bulletin. 41, 3, p. 764-71 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Danish 22q11 research initiative
Schmock, H., Vangkilde, A., Larsen, K. M., Fischer, E., Birknow, M. R., Jepsen, J. R. M., Olesen, C., Skovby, F., Plessen, K. J., Mørup, M., Hulme, O., Baaré, W. F. C., Didriksen, M., Siebner, Hartwig Roman, Werge, Thomas & Olsen, L., 2015, In: B M C Psychiatry. 15, p. 1-12 220.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Common variant at 16p11.2 conferring risk of psychosis
Steinberg, S., de Jong, S., Mattheisen, M., Costas, J., Demontis, D., Jamain, S., Pietiläinen, O. P. H., Lin, K., Papiol, S., Huttenlocher, J., Sigurdsson, E., Vassos, E., Giegling, I., Breuer, R., Fraser, G., Walker, N., Melle, I., Djurovic, S., Agartz, I., Tuulio-Henriksson, A. & 31 others, , Jan 2014, In: Molecular Psychiatry. 19, 1, p. 108-114 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence analysis of 17 NRXN1 deletions
Hoeffding, L. K. E., Hansen, T., Ingason, A., Doung, L., Thygesen, J. H., Møller, R. S., Tommerup, Niels, Kirov, G., Rujescu, D., Larsen, Lars Allan & Werge, Thomas, Jan 2014, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 165, 1, p. 52-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quetiapine versus aripiprazole in children and adolescents with psychosis - protocol for the randomised, blinded clinical Tolerability and Efficacy of Antipsychotics (TEA) trial
Pagsberg, A. K., Jeppesen, P., Klauber, D. G., Jensen, K. G., Rudå, D., Stentebjerg-Olesen, M., Jantzen, P., Rasmussen, S., Saldeen, E. A-S., Lauritsen, M-B. G., Bilenberg, N., Stenstrøm, A. D., Pedersen, J., Nyvang, L., Madsen, S., Lauritsen, M. B., Vernal, D. L., Thomsen, P. H., Paludan, J., Werge, T. M. & 9 others, , 2014, In: B M C Psychiatry. 14, p. 1-13 13 p., 199.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Psykiatrisk forskning bør have en central plads i langsigtede planer for psykiatrien
Nordentoft, Merete, Glenthøj, Birte Yding, Kessing, Lars Vedel, Parnas, Josef, Werge, Thomas, Bech, P., Fink-Jensen, Anders, Plessen, K., Simonsen, Erik, Nielsen, B., Bilenberg, N., Videbech, P., Rosenberg, R., Mors, O., Mortensen, P. B., Munk-Jørgensen, P., Hove Thomsen, P., Licht, R. & Seinhausen, C., 2 Sep 2013, In: Ugeskrift for Laeger. 175, 36, p. 2056-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does Pharmacogenetic Testing for CYP450 2D6 and 2C19 among Patients with Diagnoses within the Schizophrenic Spectrum Reduce Treatment Costs?
Herbild, L., Andersen, S. E., Werge, Thomas, Rasmussen, H. B. & Jürgens, G., 4 Jun 2013, In: Basic & Clinical Pharmacology & Toxicology. 113, 4, p. 266–272 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y genes and suicidal behaviour among schizophrenic patients
Wang, August Gabriel, Koefoed, P., Jacoby, A. S., Woldbye, David Paul Drucker, Rasmussen, Henrik Berg, Timm, S., Dam, H., Jakobsen, K. D., Nordentoft, Merete, Jürgens, Gesche, Sorensen, H. J., Garsdal, O., Hvid, M. & Werge, Thomas, Jun 2013, In: Psychiatric Genetics. 23, 3, p. 139-40 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine
Esserlind, A., Christensen, A. F., Le, H., Kirchmann, M., Hauge, A. W., Toyserkani, N. M., Hansen, Torben, Grarup, Niels, Werge, Thomas, Steinberg, S., Bettella, F., Stefansson, H. & Olesen, Jes, May 2013, In: European Journal of Neurology. 20, 5, p. 765-772 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate
Andreassen, O. A., Thompson, W. K., Schork, A. J., Ripke, S., Mattingsdal, M., Kelsoe, J. R., Kendler, K. S., O'Donovan, M. C., Rujescu, D., Werge, Thomas, Sklar, P., Roddey, J. C., Chen, C., McEvoy, L., Desikan, R. S., Djurovic, S., Dale, A. M. & Psychiatric Genomics Consortium (PGC), P. G. C. (., Apr 2013, In: P L o S Genetics (Online). 9, 4, p. e1003455Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes
Delio, M., Guo, T., McDonald-McGinn, D. M., Zackai, E., Herman, S., Kaminetzky, M., Higgins, A. M., Coleman, K., Chow, C., Jalbrzikowski, M., Jarlbrzkowski, M., Bearden, C. E., Bailey, A., Vangkilde, A., Olsen, L., Olesen, C., Skovby, F., Werge, T. M., Templin, L., Busa, T. & 38 others, , 7 Mar 2013, In: American Journal of Human Genetics. 92, 3, p. 439-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comprehensive family-based replication study of schizophrenia genes
Aberg, K. A., Liu, Y., Bukszár, J., McClay, J. L., Khachane, A. N., Andreassen, O. A., Blackwood, D., Corvin, A., Djurovic, S., Gurling, H., Ophoff, R., Pato, C. N., Pato, M. T., Riley, B., Webb, T., Kendler, K., O'Donovan, M., Craddock, N., Kirov, G., Owen, M. & 7 others, , 1 Feb 2013, In: JAMA psychiatry (Chicago, Ill.). 70, 2, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors
Andreassen, O. A., Djurovic, S., Thompson, W. K., Schork, A. J., Kendler, K. S., O'Donovan, M. C., Rujescu, D., Werge, Thomas, van de Bunt, M., Morris, A. P., McCarthy, M. I., Roddey, J. C., McEvoy, L. K., Desikan, R. S., Dale, A. M. & International Consortium for Blood Pressure GWAS, I. C. F. B. P. G., Feb 2013, In: American Journal of Human Genetics. 92, 2, p. 197-209 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Den genetiske hjerne
Tommerup, N., Christensen, K. & Werge, Thomas, 2013, Den genetiske hjerne. Hjerneforum, 88 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume
Terwisscha van Scheltinga, A. F., Bakker, S. C., van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Boos, H. B. M., Cahn, W., Hulshoff Pol, H. E., Ripke, S., Ophoff, R. A., Kahn, R. S., the Psychiatric Genome-wide Association Study Consortium, Jakobsen, K. D., Hansen, T., Ingason, A., Duong, L., Rasmussen, H. B., Olsen, L., Nordentoft, M., Jürgens, G. & 3 others, , 2013, In: Advances in Biological Psychiatry. 73, 6, p. 525-531Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC
Hamshere, M. L., Walters, J. T. R., Smith, R., Richards, A., Green, E., Grozeva, D., Jones, I., Forty, L., Jones, L. R., Gordon-Smith, K., Riley, B., O'Neill, T., Kendler, K. S., Sklar, P., Purcell, S., Kranz, J., Morris, D. J., Gill, M., Holmans, P., Craddock, N. & 13 others, , 2013, In: Molecular Psychiatry.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Redox Dysregulation in the Pathophysiology of Schizophrenia and Bipolar Disorder: Insights from Animal Models
Kulak, A., Steullet, P., Cabungcal, J., Werge, Thomas, Ingason, A., Cuenod, M. & Do, K. Q., 2013, In: Antioxidants & Redox Signaling.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Schizophrenia genetic variants are not associated with intelligence
van Scheltinga, A. F. T., Bakker, S. C., van Haren, N. E. M., Derks, E. M., Buizer-Voskamp, J. E., Cahn, W., Ripke, S., Ophoff, R. A., Kahn, R. S., Psychiatric Genome-Wide Association Study (GWAS) Consortium, P. G. A. S. (. C., Werge, Thomas, Hansen, T. & Ingason, A., 2013, In: Psychological Medicine. p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age at onset of schizophrenia: No consistent evidence for an association in the nordic population
Saetre, P., Grove, J., Børglum, A., Mors, O., Werge, Thomas, Andreassen, O. A., Vares, M., Agartz, I., Terenius, L. & Jönsson, E. G., Dec 2012, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 159B, 8, p. 981-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia
Jönsson, E. G., Saetre, P., Nyholm, H., Djurovic, S., Melle, I., Andreassen, O. A., Skjødt, C., Thygesen, J. H., Werge, Thomas, Hall, H., Agartz, I. & Terenius, L., Oct 2012, In: Psychiatric Genetics. 22, 5, p. 263-4 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Genome-wide association study of multiplex schizophrenia pedigrees
Levinson, D. F., Shi, J., Wang, K., Oh, S., Riley, B., Pulver, A. E., Wildenauer, D. B., Laurent, C., Mowry, B. J., Gejman, P. V., Owen, M. J., Kendler, K. S., Nestadt, G., Schwab, S. G., Mallet, J., Nertney, D., Sanders, A. R., Williams, N. M., Wormley, B., Lasseter, V. K. & 28 others, , Sep 2012, In: American Journal of Psychiatry. 169, 9, p. 963-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No association of polymorphisms in human endogenous retrovirus K18 and CD48 with schizophrenia
Nyegaard, M., Demontis, D., Thestrup, B. B., Hedemand, A., Sørensen, K. M., Hansen, T., Werge, Thomas, Hougaard, D. M., Yolken, R. H., Mortensen, P. B., Mors, O. & Børglum, A., Jun 2012, In: Psychiatric Genetics. 22, 3, p. 146-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia
Lindholm Carlstrom, E., Saetre, P., Rosengren, A., Thygesen, J. H., Djurovic, S., Melle, I., Andreassen, O. A., Werge, Thomas, Agartz, I., Hall, H., Terenius, L. & Jönsson, E. G., May 2012, In: Behavioral and Brain Functions. 8, 1, 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in NRXN1 in a family multiply affected with brain disorders: NRXN1 mutations and brain disorders
Duong, L., Klitten, L. L., Møller, R. S., Ingason, A., Jakobsen, K. D., Skjødt, C., Didriksen, M., Hjalgrim, H., Werge, Thomas & Tommerup, Niels, Apr 2012, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 159B, 3, p. 354-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The gene encoding the melanin-concentrating hormone receptor 1 is associated with schizophrenia in a Danish case-control sample
Demontis, D., Nyegaard, M., Christensen, J. H., Severinsen, J. E., Hedemand, A., Hansen, T., Werge, Thomas, Mors, O. & Børglum, A., Apr 2012, In: Psychiatric Genetics. 22, 2, p. 62-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Koefoed, P., Woldbye, D. P. D., Hansen, T. V. O., Eplov, L. F., Christiansen, S. H. O., Mors, O., Kessing, L. V., Werge, T., Kaipio, K., Pesonen, U., Fahmy, T., Mellerup, E. T., Jakobsen, K. D., Hansen, E. S., Knudsen, G. M., Bukh, J. D., Bock, C., Lindberg, C., Kristensen, A. S., Dam, H. & 6 others, , 23 Mar 2012, In: Acta Neuropsychiatrica. 24, 2, p. 81-90 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening of congenital heart disease patients using multiplex ligation-dependent probe amplification: early diagnosis of syndromic patients
Sørensen, K. M., El-Segaier, M., Fernlund, E., Errami, A., Bouvagnet, P., Nehme, N., Steensberg, J., Hjortdal, V. E., Soller, M., Behjati, M., Werge, Thomas, Kirchoff, M., Schouten, J., Tommerup, Niels, Andersen, P. S. & Larsen, Lars Allan, Mar 2012, In: American Journal of Medical Genetics. Part A. 158A, 4, p. 720-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Don't give up on GWAS
Sullivan, P., 96 Psychiatric Genetics Investigators, 9. P. G. I. & Werge, Thomas, Jan 2012, In: Molecular Psychiatry. 17, 1, p. 2-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia
Carrera, N., Arrojo, M., Sanjuán, J., Ramos-Ríos, R., Paz, E., Suárez-Rama, J. J., Páramo, M., Agra, S., Brenlla, J., Martínez, S., Rivero, O., Collier, D. A., Palotie, A., Cichon, S., Nöthen, M. M., Rietschel, M., Rujescu, D., Stefansson, H., Steinberg, S., Sigurdsson, E. & 12 others, , 2012, In: Biological Psychiatry. 71, 2, p. 169-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
D-amino acid oxidase activator gene (DAOA) variation affects cerebrospinal fluid homovanillic acid concentrations in healthy Caucasians
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 2012, In: European Archives of Psychiatry and Clinical Neuroscience. 262, 7, p. 549-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder
Håvik, B., Degenhardt, F. A., Johansson, S., Fernandes, C. P. D., Hinney, A., Scherag, A., Lybæk, H., Djurovic, S., Christoforou, A., Ersland, K. M., Giddaluru, S., O'Donovan, M. C., Owen, M. J., Craddock, N., Mühleisen, T. W., Mattheisen, M., Schimmelmann, B. G., Renner, T., Warnke, A., Herpertz-Dahlmann, B. & 12 others, , 2012, In: P L o S One. 7, 4, p. e35424 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does the Medication Pattern Reflect the CYP2D6 Genotype in Patients With Diagnoses Within the Schizophrenic Spectrum?
Jürgens, G., Rasmussen, H. B., Werge, Thomas, Dalhoff, Kim, Nordentoft, Merete & Andersen, S. E., 2012, In: Journal of Clinical Psychopharmacology. 32, 1, p. 100-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
Lee, S. H., DeCandia, T. R., Ripke, S., Yang, J., Sullivan, P. F., Goddard, M. E., Keller, M. C., Visscher, P. M., Wray, N. R., Schizophrenia Psychiatric Genome-Wide Association Study Consortium (PGC-SCZ), S. P. G. A. S. C. (., Hansen, T. F., Ingason, A., Olsen, L., Rasmussen, H. B. & Werge, Thomas, 2012, In: Nature Genetics. 44, 3, p. 247-50 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes
de Jong, S., van Eijk, K. R., Zeegers, D. W. L. H., Strengman, E., Janson, E., Veldink, J. H., van den Berg, L. H., Cahn, W., Kahn, R. S., Boks, M. P. M., Ophoff, R. A., PGC Schizophrenia (GWAS) Consortium, P. S. (. C., Werge, Thomas, Hansen, T., Ingason, A., Olsen, L. & Thygesen, J. H., 2012, In: European Journal of Human Genetics. 20, 9, p. 1004-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene-Based Analysis of Regionally Enriched Cortical Genes in GWAS Data Sets of Cognitive Traits and Psychiatric Disorders
Ersland, K. M., Christoforou, A., Stansberg, C., Espeseth, T., Mattheisen, M., Mattingsdal, M., Hardarson, G. A., Hansen, T., Fernandes, C. P. D., Giddaluru, S., Breuer, R., Strohmaier, J., Djurovic, S., Nöthen, M. M., Rietschel, M., Lundervold, A. J., Werge, T., Cichon, S., Andreassen, O. A., Reinvang, I. & 2 others, , 2012, In: P L o S One. 7, 2, p. e31687Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms
Fanous, A. H., Zhou, B., Aggen, S. H., Bergen, S. E., Amdur, R. L., Duan, J., Sanders, A. R., Shi, J., Mowry, B. J., Olincy, A., Amin, F., Cloninger, C. R., Silverman, J. M., Buccola, N. G., Byerley, W. F., Black, D. W., Freedman, R., Dudbridge, F., Holmans, P. A., Ripke, S. & 8 others, , 2012, In: American Journal of Psychiatry. 169, 12, p. 1309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis
Derks, E. M., Vorstman, J. A. S., Ripke, S., Kahn, R. S., Ophoff, R. A., Schizophrenia Psychiatric Genomic Consortium, S. P. G. C., Hansen, T., Olsen, L., Jakobsen, K. D., Schmock, H., Skjødt, C., Rosengren, A., Høffding, L. K. E., Thygesen, J. H. & Werge, Thomas, 2012, In: P L o S One. 7, 6, p. e37852Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls
Holtze, M., Saetre, P., Engberg, G., Schwieler, L., Werge, Thomas, Andreassen, O. A., Hall, H., Terenius, L., Agartz, I., Jönsson, E. G., Schalling, M. & Erhardt, S., 2012, In: Journal of Psychiatry and Neuroscience. 37, 1, p. 53-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events
Haastrup, E., Bukh, Jens Otto Drachmann, Bock, C., Vinberg, Maj, Thørner, L. W., Hansen, T., Werge, Thomas, Kessing, Lars Vedel & Ullum, H., 2012, In: Journal of Affective Disorders. 136, 1-2, p. 134-138 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication study and meta-analysis in European samples supports association of the 3p21.1 locus with bipolar disorder
Vassos, E., Steinberg, S., Cichon, S., Breen, G., Sigurdsson, E., Andreassen, O. A., Djurovic, S., Morken, G., Grigoroiu-Serbanescu, M., Diaconu, C. C., Czerski, P. M., Hauser, J., Babadjanova, G., Abramova, L. I., Mühleisen, T. W., Nöthen, M. M., Rietschel, M., McGuffin, P., St Clair, D., Gustafsson, O. & 28 others, , 2012, In: Biological Psychiatry. 72, 8, p. 645-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to Boot et al. Letter
Werge, Thomas, Ingason, A., Kirov, G., Rujescu, D. & Sigurdsson, E., 2012, In: American Journal of Psychiatry. 169, 1, p. 97 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Runs of homozygosity implicate autozygosity as a schizophrenia risk factor
Keller, M. C., Simonson, M. A., Ripke, S., Neale, B. M., Gejman, P. V., Howrigan, D. P., Lee, S. H., Lencz, T., Levinson, D. F., Sullivan, P. F., Schizophrenia Psychiatric Genome-Wide Association Study Consortium, S. P. G. A. S. C., Hansen, T., Ingason, A., Olsen, L., Schmock, H., Skjødt, C., Thygesen, J. H., Rosengren, A. & Werge, Thomas, 2012, In: P L o S Genetics. 8, 4, p. e1002656Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utility and adoption of CYP2D6 and CYP2C19 genotyping and its translation into psychiatric clinical practice
Jürgens, G., Jacobsen, C. B., Rasmussen, H. B., Werge, T., Nordentoft, Merete, Andersen, S. E. & Werge, Thomas, 2012, In: Acta Psychiatrica Scandinavica. 125, 3, p. 228-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples
Tesli, M., Koefoed, P., Athanasiu, L., Mattingsdal, M., Gustafsson, O., Agartz, I., Rimol, L. M., Brown, A., Wirgenes, K. V., Smorr, L., Kähler, A. K., Werge, Thomas, Mors, O., Mellerup, Erling Thyge, Jönsson, E. G., Melle, I., Morken, G., Djurovic, S. & Andreassen, O. A., 1 Dec 2011, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 8, p. 969-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of GRIN1 and GRIN2A-D With schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk
Demontis, D., Nyegaard, M., Buttenschøn, H. N., Hedemand, A., Pedersen, C. B., Grove, J., Zacharov, T. F., Nordentoft, Merete, Werge, Thomas, Hougaard, D. M., Sørensen, K. M., Yolken, R. H., Mors, O., Børglum, A. & Mortensen, P. B., 1 Dec 2011, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 8, p. 913-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia
Shi, Y., Li, Z., Xu, Q., Wang, T., Li, T., Shen, J., Zhang, F., Chen, J., Zhou, G., Ji, W., Li, B., Xu, Y., Liu, D., Wang, P., Yang, P., Liu, B., Sun, W., Wan, C., Qin, S., He, G. & 21 others, , Dec 2011, In: Nature Genetics. 43, 12, p. 1224-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies four loci associated with eruption of permanent teeth
Geller, F., Feenstra, B., Zhang, H., Shaffer, J. R., Hansen, T., Esserlind, A-L., Boyd, H. A., Nohr, E. A., Timpson, N. J., Fatemifar, G., Paternoster, L., Evans, D. M., Weyant, R. J., Levy, S. M., Lathrop, M., Smith, G. D., Murray, J. C., Olesen, J., Werge, T. M., Marazita, M. L. & 2 others, , 1 Sep 2011, In: P L o S Genetics. 7, 9, p. e1002275Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dystrobrevin-binding protein 1 gene (DTNBP1) variants associated with cerebrospinal fluid homovanillic acid and 5-hydroxyindoleacetic acid concentrations in healthy volunteers
Andreou, D., Saetre, P., Kähler, A. K., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., Sep 2011, In: European Neuropsychopharmacology. 21, 9, p. 700-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combinations of SNPs Related to Signal Transduction in Bipolar Disorder
Koefoed, P., Andreassen, O. A., Bennike, B., Dam, H., Djurovic, S., Hansen, T., Jorgensen, M. B., Kessing, Lars Vedel, Melle, I., Møller, G. L., Mors, O., Werge, Thomas & Mellerup, Erling Thyge, 1 Aug 2011, In: P L o S One. 6, 8, p. e23812 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia
Caprini, S., Saetre, P., Melle, I., Djurovic, S., Andreassen, O. A., Skjødt, C., Doung, L., Werge, Thomas, Hall, H., Agartz, I., Terenius, L. & Jönsson, E. G., 1 Aug 2011, In: Psychiatric Genetics. 21, 4, p. 214-5 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Common Variants at VRK2 and TCF4 Conferring Risk of Schizophrenia
Irish Schizophrenia Genomics Consortium, I. S. G. C., GROUP, G. & Wellcome Trust Case Control Consortium, W. T. C. C. C., 26 Jul 2011, In: Human Molecular Genetics. 20, 20, p. 4076-4081Research output: Contribution to journal › Journal article › Research › peer-review
- Published
At-Risk Variant in TCF7L2 for Type II Diabetes Increases Risk of Schizophrenia
Hansen, T., Ingason, A., Djurovic, S., Melle, I., Fenger, M., Gustafsson, O., Jakobsen, K. D., Rasmussen, H. B., Tosato, S., Rietschel, M., Frank, J., Owen, M., Bonetto, C., Suvisaari, J., Thygesen, J. H., Pétursson, H., Lönnqvist, J., Sigurdsson, E., Giegling, I., Craddock, N. & 12 others, , 1 Jul 2011, In: Biological Psychiatry. 70, 1, p. 59-63 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes
Pers, T. H., Hansen, N. T., Hansen, K. L., Koefoed, P., Dworzynski, P., Miller, M. L., Flint, T. J., Mellerup, E., Dam, H., Andreassen, O. A., Djurovic, S., Melle, I., Børglum, A. D., Werge, T., Purcell, S., Ferreira, M. A., Kouskoumvekaki, I., Workman, C., Hansen, T., Mors, O. & 1 others, , 11 Apr 2011, In: Genetic Epidemiology. 35, 5, p. 318-332 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A rare variant in MYH6 is associated with high risk of sick sinus syndrome
Holm, H., Gudbjartsson, D. F., Sulem, P., Masson, G., Helgadottir, H. T., Zanon, C., Magnusson, O. T., Helgason, A., Saemundsdottir, J., Gylfason, A., Stefansdottir, H., Gretarsdottir, S., Matthiasson, S. E., Thorgeirsson, G. M., Jonasdottir, A., Sigurdsson, A., Stefansson, H., Werge, T., Rafnar, T., Kiemeney, L. A. & 10 others, , 1 Apr 2011, In: Nature Genetics. 43, 4, p. 316-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternally Derived Microduplications at 15q11-q13: Implication of Imprinted Genes in Psychotic Illness
Ingason, A., Kirov, G., Giegling, I., Hansen, T., Isles, A. R., Jakobsen, K. D., Kristinsson, K. T., le Roux, L., Gustafsson, O., Craddock, N., Möller, H-J., McQuillin, A., Muglia, P., Cichon, S., Rietschel, M., Ophoff, R. A., Djurovic, S., Andreassen, O. A., Pietiläinen, O. P. H., Peltonen, L. & 22 others, , 1 Apr 2011, In: American Journal of Psychiatry. 168, 4, p. 408-417 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: An association study
Holtze, M., Saetre, P., Erhardt, S., Schwieler, L., Werge, Thomas, Hansen, Thomas Folkmann, Nielsen, J., Djurovic, S., Melle, I., Andreassen, O. A., Hall, H., Terenius, L., Agartz, I., Engberg, G., Jönsson, E. G. & Schalling, M., Apr 2011, In: Schizophrenia Research. 127, 1-3, p. 270-2 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Do guidelines recommending pharmacogenetic testing of psychiatric patients affect treatment costs and the use of healthcare services?
Herbild, L., Bech, M., Gyrd-Hansen, D., Christensen, M., Werge, Thomas & Nielsen, K. A., Mar 2011, In: Scandinavian Journal of Public Health. 39, 2, p. 147-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: A combined analysis of independent samples
Saetre, P., Vares, M., Werge, T., Andreassen, O. A., Arinami, T., Ishiguro, H., Nanko, S., Tan, E. C., Han, D. H., Roffman, J. L., Muntjewerff, J-W., Jagodzinski, P. P., Kempisty, B., Hauser, J., Vilella, E., Betcheva, E., Nakamura, Y., Regland, B., Agartz, I., Hall, H. & 2 others, , Mar 2011, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 2, p. 215-24 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area
Kähler, A. K., Djurovic, S., Rimol, L. M., Brown, A. A., Athanasiu, L., Jönsson, E. G., Hansen, T., Gústafsson, O., Hall, H., Giegling, I., Muglia, P., Cichon, S., Rietschel, M., Pietiläinen, O. P. H., Peltonen, L., Bramon, E., Collier, D., St Clair, D., Sigurdsson, E., Petursson, H. & 8 others, , 1 Jan 2011, In: Biological Psychiatry. 69, 1, p. 90-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copy number variations of chromosome 16p13.1 region associated with schizophrenia
Ingason, A., Rujescu, D., Cichon, S., Sigurdsson, E., Sigmundsson, T., Pietiläinen, O. P. H., Buizer-Voskamp, J. E., Strengman, E., Francks, C., Muglia, P., Gylfason, A., Gustafsson, O., Olason, P. I., Steinberg, S., Hansen, T. F., Jakobsen, K. D., Rasmussen, H. B., Giegling, I., Möller, H-J., Hartmann, A. & 29 others, , 1 Jan 2011, In: Molecular Psychiatry. 16, 1, p. 17-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expanding the range of ZNF804A variants conferring risk of psychosis
Steinberg, S., Mors, O., Børglum, A., Gustafsson, O., Werge, T., Mortensen, P. B., Andreassen, O. A., Sigurdsson, E., Thorgeirsson, T. E., Böttcher, Y., Olason, P., Ophoff, R. A., Cichon, S., Gudjonsdottir, I. H., Pietiläinen, O. P. H., Nyegaard, M., Tuulio-Henriksson, A., Ingason, A., Hansen, T. F., Athanasiu, L. & 31 others, , Jan 2011, In: Molecular Psychiatry. 16, 1, p. 59-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered limbic microstructure in antipsychotic-naïve first-episode schizophrenia patients and associations with the schizophrenia susceptibility gene ZNF804A
Ebdrup, B., Baare, W., Hansen, T., Rasmussen, H., Aggernæs, B., Werge, Thomas, Glenthøj, Birte Yding & Skimminge, A., 2011. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Copy number variations in affective disorders and meta-analysis
Olsen, L., Hansen, T., Djurovic, S., Haastrup, E., Albrecthsen, A., Hoeffding, L. K. E., Secher, A., Gustafsson, O., Jakobsen, K. D., Nielsen, Finn Cilius, Ullum, H., Morken, G., Agartz, I., Melle, I., Gether, Ulrik, Andreassen, O. A. & Werge, Thomas, 2011, In: Psychiatric Genetics. 21, 6, p. 319-322 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual association of a TRKA polymorphism with schizophrenia
Van Schijndel, J. E., Van Zweeden, M., Van Loo, K. M. J., Djurovic, S., Andreassen, O. A., Hansen, T., Werge, T., Nyegaard, M., Sørensen, K. M., Nordentoft, M., Mortensen, P. B., Mors, O., Børglum, A., Del-Favero, J., Norrback, K-F., Adolfsson, R., Hert, M. D., Claes, S., Cichon, S., Rietschel, M. & 4 others, , 2011, In: Psychiatric Genetics. 21, 3, p. 125-31 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of cannabinoid CB(1) receptor agonism and antagonism on SKF81297-induced dyskinesia and haloperidol-induced dystonia in Cebus apella monkeys
Madsen, M. V., Peacock, L. P., Werge, Thomas, Andersen, M. H. & Andreasen T., Jesper, 2011, In: Neuropharmacology. 60, 2-3, p. 418-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia
Chen, X., Lee, G., Maher, B. S., Fanous, A. H., Chen, J., Zhao, Z., Guo, A., van den Oord, E., Sullivan, P. F., Shi, J., Levinson, D. F., Gejman, P. V., Sanders, A., Duan, J., Owen, M. J., Craddock, N. J., O'Donovan, M. C., Blackman, J., Lewis, D., Kirov, G. K. & 42 others, , 2011, In: Molecular Psychiatry. 16, 11, p. 1117-29 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure
Rasmussen, H. B. & Werge, Thomas, 2011, In: Pharmacological Reports. 63, 5, p. 1264-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia
Håvik, B., Le Hellard, S., Rietschel, M., Lybæk, H., Djurovic, S., Mattheisen, M., Mühleisen, T. W., Degenhardt, F., Priebe, L., Maier, W., Breuer, R., Schulze, T. G., Agartz, I., Melle, I., Hansen, T., Bramham, C. R., Nöthen, M. M., Stevens, B., Werge, T., Andreassen, O. A. & 2 others, , 2011, In: Biological Psychiatry. 70, 1, p. 35-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using electronic patient records to discover disease correlations and stratify patient cohorts
Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., Søeby, K., Bredkjær, S., Juul, Anders, Werge, Thomas, Jensen, Lars Juhl & Brunak, Søren, 2011, In: P L o S Computational Biology. 7, 8, p. e1002141 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers
Andreou, D., Saetre, P., Werge, Thomas, Andreassen, O. A., Agartz, I., Sedvall, G. C., Hall, H., Terenius, L. & Jönsson, E. G., 30 Dec 2010, In: Psychiatry Research. 180, 2-3, p. 63-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
Haukvik, U. K., Saetre, P., McNeil, T., Bjerkan, P. S., Andreassen, O. A., Werge, Thomas, Jönsson, E. G. & Agartz, I., 1 Oct 2010, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 34, 7, p. 1259-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
Anttila, V., Stefansson, H., Kallela, M., Todt, U., Terwindt, G. M., Calafato, M. S., Nyholt, D. R., Dimas, A. S., Freilinger, T., Müller-Myhsok, B., Artto, V., Inouye, M., Alakurtti, K., Kaunisto, M. A., Hämäläinen, E., de Vries, B., Stam, A. H., Weller, C. M., Heinze, A., Heinze-Kuhn, K. & 31 others, , 1 Oct 2010, In: Nature Genetics. 42, 10, p. 869-73 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample
Tesli, M., Athanasiu, L., Mattingsdal, M., Kähler, A. K., Gustafsson, O., Andreassen, B. K., Werge, Thomas, Hansen, T., Mors, O., Mellerup, Erling Thyge, Koefoed, P., Jönsson, E. G., Agartz, I., Melle, I., Morken, G., Djurovic, S. & Andreassen, O. A., Oct 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 7, p. 1276-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No influence of the polymorphisms CYP2C19 and CYP2D6 on the efficacy of cyclophosphamide, thalidomide, and bortezomib in patients with Multiple Myeloma
Vangsted, A. J., Søeby, K., Klausen, T. W., Abildgaard, N., Andersen, N. F., Gimsing, P., Gregersen, H., Vogel, U., Werge, Thomas & Rasmussen, Henrik Berg, 4 Aug 2010, In: B M C Cancer. 10, p. 404 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples
Le Hellard, S., Mühleisen, T. W., Djurovic, S., Fernø, J., Ouriaghi, Z., Mattheisen, M., Vasilescu, C., Raeder, M. B., Hansen, T. F., Strohmaier, J., Georgi, A., Brockschmidt, F. F., Melle, I., Nenadic, I., Sauer, H., Rietschel, M., Nöthen, M. M., Werge, T., Andreassen, O. A., Cichon, S. & 1 others, , 1 May 2010, In: Molecular Psychiatry. 15, 5, p. 463-72 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia
Ingason, A., Giegling, I., Cichon, S., Hansen, T., Rasmussen, H. B., Nielsen, J., Jürgens, G., Muglia, P., Hartmann, A. M., Strengman, E., Vasilescu, C., Mühleisen, T. W., Djurovic, S., Melle, I., Lerer, B., Möller, H-J., Francks, C., Pietiläinen, O. P. H., Lonnqvist, J., Suvisaari, J. & 21 others, , 1 Apr 2010, In: Human Molecular Genetics. 19, 7, p. 1379-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Det genetiske grundlag for psykiske lidelser
Werge, Thomas & Fink-Jensen, Anders, 22 Mar 2010, In: Ugeskrift for Laeger. 172, 12, p. 962 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia
Vares, M., Saetre, P., Deng, H., Cai, G., Liu, X., Hansen, Thomas Folkmann, Rasmussen, Henrik Berg, Werge, Thomas, Melle, I., Djurovic, S., Andreassen, O. A., Agartz, I., Hall, H., Terenius, L. & Jönsson, E. G., 5 Mar 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 2, p. 610-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis
Saetre, P., Lundmark, P., Wang, August Gabriel, Hansen, Thomas Folkmann, Rasmussen, Henrik Berg, Djurovic, S., Melle, I., Andreassen, O. A., Werge, Thomas, Agartz, I., Hall, H., Terenius, L. & Jönsson, E. G., 5 Mar 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 2, p. 387-96 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic susceptibility factors for multiple chemical sensitivity revisited
Berg, N. D., Rasmussen, Henrik Berg, Linneberg, Allan René, Andersen, C. B., Fenger, M., Dirksen, A., Vesterhauge, S., Werge, Thomas, Elberling, J. & Berg, N. D., 1 Mar 2010, In: International Journal of Hygiene and Environmental Health. 213, 2, p. 131-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CACNA1C (rs1006737) is associated with schizophrenia
Nyegaard, M., Demontis, D., Foldager, L., Hedemand, A., Flint, T. J., Sørensen, K. M., Andersen, P. S., Nordentoft, Merete, Werge, Thomas, Pedersen, C. B., Hougaard, D. M., Mortensen, P. B., Mors, O. & Børglum, A. D., 1 Feb 2010, In: Molecular Psychiatry. 15, 2, p. 119-21 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Association study of PDE4B gene variants in Scandinavian schizophrenia and bipolar disorder multicenter case-control samples
Kähler, A. K., Otnæss, M. K., Wirgenes, K. V., Hansen, T., Jönsson, E. G., Agartz, I., Hall, H., Werge, T., Morken, G., Mors, O., Mellerup, E., Dam, H., Koefoed, P., Melle, I., Steen, V. M., Andreassen, O. A., Djurovic, S., Kähler, A. K., Otnaess, M. K., Wirgenes, K. V. & 14 others, , 2010, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 153B, 1, p. 86-96 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Common variants conferring risk of schizophrenia
Stefansson, H., Ophoff, R. A., Steinberg, S., Andreassen, O. A., Cichon, S., Rujescu, D., Werge, T., Pietiläinen, O. P. H., Mors, O., Mortensen, P. B., Sigurdsson, E., Gustafsson, O., Nyegaard, M., Tuulio-Henriksson, A., Ingason, A., Hansen, T., Suvisaari, J., Lonnqvist, J., Paunio, T., Børglum, A. D. & 31 others, , 6 Aug 2009, In: Nature. 460, 7256, p. 744-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
Gudbjartsson, D. F., Bjornsdottir, U. S., Halapi, E., Helgadottir, A., Sulem, P., Jonsdottir, G. M., Thorleifsson, G., Helgadottir, H., Steinthorsdottir, V., Stefansson, H., Williams, C., Hui, J., Beilby, J., Warrington, N. M., James, A., Palmer, L. J., Koppelman, G. H., Heinzmann, A., Krueger, M., Boezen, H. M. & 53 others, , Mar 2009, In: Nature Genetics. 41, 3, p. 342-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE)
Djurovic, S., Kähler, A. K., Kulle, B., Jönsson, E. G., Agartz, I., Le Hellard, S., Hall, H., Jakobsen, K. D., Hansen, T., Melle, I., Werge, T., Steen, V. M., Andreassen, O. A., Djurovic, S., Kähler, A. K., Kulle, B., Jönsson, E. G., Agartz, I., Le Hellard, S., Hall, H. & 6 others, , 2009, In: Schizophrenia Research. 107, 2-3, p. 242-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population
Lu, T. T., Lao, O., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Nielsen, F., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A. & 14 others, , 2009, In: European Journal of Human Genetics. 17, 7, p. 967-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An intron 1 polymorphism in the cholecystokinin-A receptor gene associated with schizophrenia in males
Koefoed, P., Hansen, T. V. O., Woldbye, D. P. D., Werge, T., Mors, O., Hansen, T., Jakobsen, K. D., Nordentoft, M., Wang, A., Bolwig, T. G., Rehfeld, J. F., Koefoed, P., Hansen, T. V. O., Woldbye, D. P. D., Werge, T., Mors, O., Hansen, T. F., Jakobsen, K. D., Nordentoft, M., Wang, A. & 2 others, , 2009, In: Acta Psychiatrica Scandinavica. 120, 4, p. 281-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidepressive-drug-induced bodyweight gain is associated with polymorphisms in genes coding for COMT and TPH1
Secher, A., Bukh, J., Bock, C., Koefoed, P., Rasmussen, H. B., Werge, T., Kessing, Lars Vedel, Mellerup, Erling Thyge, Secher, A., Bukh, J., Bock, C., Koefoed, P., Rasmussen, H. B., Werge, Thomas, Kessing, Lars Vedel & Mellerup, E., 2009, In: International Clinical Psychopharmacology. 24, 4, p. 199-203 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)
Djurovic, S., Le Hellard, S., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G., Rasmussen, H. B., Melle, I., Werge, T., Andreassen, O. A., Djurovic, S., Le Hellard, S., Kähler, A. K., Jönsson, E. G., Agartz, I., Steen, V. M., Hall, H., Wang, A. G. & 4 others, , 2009, In: Psychiatry Research. 168, 3, p. 256-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CYP2D6 genotype predicts antipsychotic side effects in schizophrenia inpatients: a retrospective matched case-control study
Kobylecki, C. J., Jakobsen, K. D., Hansen, T., Jakobsen, I. V., Rasmussen, H. B., Werge, Thomas, Kobylecki, C. J., Jakobsen, K. D., Hansen, T., Jakobsen, I. V., Rasmussen, H. B. & Werge, Thomas, 2009, In: Neuropsychobiology. 59, 4, p. 222-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study
Jönsson, E. G., Saetre, P., Vares, M., Andreou, D., Larsson, K., Timm, S., Rasmussen, H. B., Djurovic, S., Melle, I., Andreassen, O. A., Agartz, I., Werge, T., Hall, H., Terenius, L., Jönsson, E. G., Saetre, P., Vares, M., Andreou, D., Larsson, K., Timm, S. & 8 others, , 2009, In: Neuropsychobiology. 59, 3, p. 142-50 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of the neurexin 1 gene is associated with schizophrenia
Rujescu, D., Ingason, A., Cichon, S., Pietiläinen, O. P. H., Barnes, M. R., Toulopoulou, T., Picchioni, M., Vassos, E., Ettinger, U., Bramon, E., Murray, R., Ruggeri, M., Tosato, S., Bonetto, C., Steinberg, S., Sigurdsson, E., Sigmundsson, T., Petursson, H., Gylfason, A., Olason, P. I. & 31 others, , 2009, In: Human Molecular Genetics. 18, 5, p. 988-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dysbindin and d-amino-acid-oxidase gene polymorphisms associated with positive and negative symptoms in schizophrenia
Wirgenes, K. V., Djurovic, S., Agartz, I., Jonsson, E. G., Werge, Thomas, Melle, I., Andreassen, O. A., Wirgenes, K. V., Djurovic, S., Agartz, I., Jonsson, E. G., Werge, Thomas, Melle, I. & Andreassen, O. A., 2009, In: Neuropsychobiology. 60, 1, p. 31-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia
Otnaess, M. K., Djurovic, S., Rimol, L. M., Kulle, B., Kähler, A. K., Jönsson, E. G., Agartz, I., Sundet, K., Hall, H., Timm, S., Hansen, T., Callicott, J. H., Melle, I., Werge, T., Andreassen, O. A., Otnaess, M. K., Djurovic, S., Rimol, L. M., Kulle, B., Kähler, A. K. & 10 others, , 2009, In: Neurobiology of Disease. 34, 3, p. 518-24 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between genetic polymorphisms and stressful life events in first episode depression
Bukh, Jens Otto Drachmann, Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In: Journal of Affective Disorders. 119, 1-3, p. 107-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of association of the serotonin transporter gene promoter region polymorphism, 5-HTTLPR, including rs25531 with cigarette smoking and alcohol consumption
Rasmussen, H., Bagger, Y., Tanko, L. B., Christiansen, C., Werge, Thomas, Rasmussen, H., Bagger, Y., Tanko, L. B., Christiansen, C. & Werge, Thomas, 2009, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 150B, 4, p. 575-80 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats
Olsen, L., Klausen, M., Helboe, L., Nielsen, Finn Cilius, Werge, Thomas, Olsen, L., Klausen, M., Helboe, L., Nielsen, Finn Cilius & Werge, Thomas, 2009, In: PLoS ONE. 4, 10, p. e7225 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation screening of the glutamate cysteine ligase modifier (GCLM) gene in patients with schizophrenia
Butticaz, C., Werge, Thomas, Beckmann, J. S., Cuénod, M., Do, K. Q., Rivolta, C., Butticaz, C., Werge, Thomas, Beckmann, J. S., Cuénod, M., Do, K. Q. & Rivolta, C., 2009, In: Psychiatric Genetics. 19, 4, p. 201-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No association between DGKH and bipolar disorder in a Scandinavian case-control sample
Tesli, M., Kähler, A., Andreassen, B., Werge, T., Mors, O., Mellerup, E., Koefoed, P., Melle, I., Morken, G., Wirgenes, K., Andreassen, O., Djurovic, S., Tesli, M., Kähler, A. K., Andreassen, B. K., Werge, T., Mors, O., Mellerup, E., Koefoed, P., Melle, I. & 4 others, , 2009, In: Psychiatric Genetics. 19, 5, p. 269-72 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment
Bukh, Jens Otto Drachmann, Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In: European Neuropsychopharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes
Kring, S. I. I., Werge, Thomas, Holst, C., Toubro, S., Astrup, A., Hansen, Torben, Pedersen, Oluf Borbye & Sørensen, Thorkild I.A., 2009, In: PLoS ONE. 4, 8, p. e6696 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
Gudbjartsson, D. F., Bjornsdottir, U. S., Halapi, E., Helgadottir, A., Sulem, P., Jonsdottir, G. M., Thorleifsson, G., Helgadottir, H., Steinthorsdottir, V., Stefansson, H., Williams, C., Hui, J., Beilby, J., Warrington, N. M., James, A., Palmer, L. J., Koppelman, G. H., Heinzmann, A., Krueger, M., Boezen, H. M. & 126 others, , 2009, In: Nature Genetics. 41, 3, p. 342-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suicidal Behavior and the Serotonin Transporter Gene Polymorphism (5-HTTLPR) with Novel Subtypes, in Danish Schizophrenic Patients
Wang, August Gabriel, Rasmussen, Henrik Berg, Sørensen, H. J., Hvid, M., Breddam, C. H., Hansen, B., Bille, V. H., Garsdal, O., Jacoby, A., Søbye, K., Dam, O. H., Krogsbøl, H., Timm, S. & Werge, Thomas, 2009, In: Open Psychiatry Journal.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The prevalence and early life determinants of mental disorders in school aged children: 11 years follow up of the CCC 2000 birth cohort study. Poster presentation XVII.ESCAP International Congress Budapest August 2009
Jeppesen, Pia, Fagerlund, Birgitte, Glenthøj, Birte Yding, Werge, Thomas, Linneberg, Allan René, Jørgensen, T. & Skovgaard, A. M., 2009. 0 p.Research output: Contribution to conference › Poster › Research › peer-review
- Published
Three-cohort targeted gene screening reveals a non-synonymous TRKA polymorphism associated with schizophrenia
van Schijndel, J. E., van Loo, K. M. J., van Zweeden, M., Djurovic, S., Andreassen, O. A., Hansen, Thomas Folkmann, Werge, Thomas, Kallunki, P., Pedersen, J. T. & Martens, G. J. M., 2009, In: Journal of Psychiatric Research. 43, 15, p. 1195-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Triton X-100 inhibits agonist-induced currents and suppresses benzodiazepine modulation of GABA(A) receptors in Xenopus oocytes
Søgaard, R., Ebert, B., Klærke, Dan Arne, Werge, Thomas, Søgaard, R., Ebert, B., Klaerke, D. & Werge, Thomas, 2009, In: B B A - Biomembranes. 1788, 5, p. 1073-80 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia
Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S., Andreassen, O. A., Werge, T., Hall, H., Agartz, I., Terenius, L., Jönsson, E. G., Andreou, D., Saetre, P., Lundmark, P., Hansen, T., Timm, S., Melle, I., Djurovic, S. & 6 others, , 2009, In: Psychiatric Genetics. 19, 5, p. 273-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Advice on the genotyping of CYP2C19: comments on a recent article
Rasmussen, H. B. & Werge, Thomas, 2008, In: Pharmacogenetics and Genomics (Print Edition). 18, 7, p. 647-648 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene
Kähler, A. K., Djurovic, S., Kulle, B., Jönsson, E. G., Agartz, I., Hall, H., Opjordsmoen, S., Jakobsen, K. D., Hansen, T., Melle, I., Werge, Thomas, Steen, V. M. & Andreassen, O. A., 2008, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 147B, 7, p. 1089-100 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of a dopamine beta-hydroxylase gene variant with depression in elderly women possibly reflecting noradrenergic dysfunction
Togsverd, M., Tanko, L. B., Bagger, Y. Z., Hansen, T., Qin, G., Christiansen, C., Rasmussen, H. B. & Werge, Thomas, 2008, In: Journal of Affective Disorders. 106, 1-2, p. 169-172 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correlation between genetic and geographic structure in Europe
Lao, O., Lu, T. T., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A., Gether, U. & 13 others, , 2008, In: Current Biology. 18, 16, p. 1241-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large recurrent microdeletions associated with schizophrenia
Stefansson, H., Rujescu, D., Cichon, S., Pietilainen, O. P., Ingason, A., Steinberg, S., Fossdal, R., Sigurdsson, E., Sigmundsson, T., Buizer-Voskamp, J. E., Hansen, T., Jakobsen, K. D., Muglia, P., Francks, C., Matthews, P. M., Gylfason, A., Halldorsson, B. V., Gudbjartsson, D., Thorgeirsson, T. E., Sigurdsson, A. & 31 others, , 2008, In: Nature Study. 455, 7210, p. 232-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Misclassification of allele CYP2C19*10 as CY2C19*2 by a commonly used PCR-RFLP procedure
Rasmussen, H. & Werge, Thomas, 2008, In: Genetic Testing. 12, 1, p. 57-58 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reliability of clinical ICD-10 diagnoses among electroconvulsive therapy patients with chronic affective disorders
Jakobsen, K. D., Hansen, T. F., Dam, H., Larsen, E. B., Gether, Ulrik & Werge, Thomas, 2008, In: European Journal of Psychiatry. 22, 3, p. 161-172 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Submikroskopiske kromosomanomalier som arsag til skizofreni
Hansen, T., Ingason, A. & Werge, Thomas, 2008, In: Ugeskrift for læger. 170, 46, p. 3773-3776 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Submikroskopiske kromosomanomalier som årsag til skizofreni
Hansen, T., Ingason, A. & Werge, Thomas, 2008, In: Ugeskrift for Laeger. 170, 46, p. 3773-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples
Olsen, L., Hansen, T., Jakobsen, K. D., Djurovic, S., Melle, I., Agartz, I., Hall, H., Ullum, H., Timm, S., Wang, August Gabriel, Jönsson, E. G., Andreassen, O. A. & Werge, Thomas, 2008, In: B M C Medical Genetics. 9, p. 39Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of CYP2D6 and CYP2C19 polymorphisms on suicidal behavior and substance abuse disorder among patients with schizophrenia: a retrospective study
Kobylecki, C. J., Hansen, T., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Sørensen, H. J., Rasmussen, H. B., Werge, T. M., Kobylecki, C. J., Hansen, T. F., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Sørensen, H. J., Rasmussen, H. B. & Werge, Thomas, 2008, In: Therapeutic Drug Monitoring. 30, 3, p. 265-70 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study
Jönsson, E. G., Larsson, K., Vares, M., Hansen, T., Wang, August Gabriel, Djurovic, S., Rønningen, K. S., Andreassen, O. A., Agartz, I., Werge, Thomas, Terenius, L. & Hall, H., 2008, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 147B, 6, p. 976-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in the purinergic P2RX(7) receptor gene and schizophrenia
Hansen, T., Jakobsen, K. D., Fenger, M., Nielsen, J., Krane, K., Fink-Jensen, Anders, Lublin, H., Ullum, H., Timm, S., Wang, August Gabriel, Jørgensen, Niklas Rye & Werge, Thomas, 2008, In: Schizophrenia Research. 104, 1-3, p. 146-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
A closed-tube assay for genotyping of the 32-bp deletion polymorphism in the chemokine receptor 5 (CCR5) gene: dissociation analysis of amplified fragments of DNA
Rasmussen, H. B. & Werge, Thomas, 2007, In: Molecular and Cellular Probes. 21, 1, p. 8-11 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain expressed microRNAs implicated in schizophrenia etiology
Hansen, T., Olsen, L., Lindow, M., Jakobsen, K. D., Ullum, H., Jonsson, E., Andreassen, O. A., Djurovic, S., Melle, I., Agartz, I., Hall, H., Timm, S., Wang, August Gabriel & Werge, Thomas, 2007, In: P L o S One. 2, 9, p. e873Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive performance in elderly women: significance of the 19bp insertion/deletion polymorphism in the 5' flank of the dopamine beta-hydroxylase gene, educational level, body fat measures, serum triglyceride, alcohol consumption and age
Togsverd, M., Werge, Thomas, Tankó, L. B., Bagger, Y. Z., Qin, G. G., Hansen, T., Christiansen, C. & Rasmussen, H. B., 2007, In: International Journal of Geriatric Psychiatry. 22, 9, p. 883-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic stability among chronic patients with functional psychoses: an epidemiological and clinical study
Jakobsen, K. D., Hansen, T. & Werge, Thomas, 2007, In: B M C Psychiatry. 7, p. 41Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se?
Bagger, Y. Z., Rasmussen, H. B., Alexandersen, P., Werge, Thomas, Christiansen, C., Tankó, L. B. & PERF study group, P. S. G., 2007, In: Osteoporosis International. 18, 4, p. 505-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects
Passos Gregorio, S., Gattaz, W. F., Tavares, H., Kieling, C., Timm, S., Wang, August Gabriel, Berg Rasmussen, H., Werge, Thomas & Dias-Neto, E., 2006, In: Schizophrenia Research. 88, 1-3, p. 275-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between the CCR5 32-bp deletion allele and late onset of schizophrenia
Rasmussen, H. B., Timm, S., Wang, A. G., Soby, K., Lublin, H., Fenger, M., Hemmingsen, R., Werge, T., Rasmussen, H. B., Timm, S., Wang, August Gabriel, Søeby, K., Lublin, H., Hemmingsen, R. P. A. & Werge, Thomas, 2006, In: American Journal of Psychiatry. 163, 3, p. 507-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostic agreement of schizophrenia spectrum disorders among chronic patients with functional psychoses
Jakobsen, K. D., Frederiksen, J. N., Parnas, Josef & Werge, Thomas, 2006, In: Psychopathology. 39, 6, p. 269-76 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estrogen receptor alpha and risk for cognitive impairment in postmenopausal women
Olsen, L., Rasmussen, H. B., Hansen, T., Bagger, Y. Z., Tankó, L. B., Qin, G., Christiansen, C. & Werge, Thomas, 2006, In: Psychiatric Genetics. 16, 2, p. 85-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of a tandem repeat in exon III of the dopamine receptor D4 (DRD4) gene in cetaceans
Mogensen, L., Kinze, C. C., Werge, Thomas & Rasmussen, H. B., 2006, In: Journal of Heredity. 97, 3, p. 279-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No significant association of the 5' end of neuregulin 1 and schizophrenia in a large Danish sample
Ingason, A., Søeby, K., Timm, S., Wang, August Gabriel, Jakobsen, K. D., Fink-Jensen, Anders, Hemmingsen, R. P. A., Berg Rasmussen, H. & Werge, Thomas, 2006, In: Schizophrenia Research. 83, 1, p. 1-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The substituted (S)-3-phenylpiperidine (-)-OSU6162 reduces apomorphine- and amphetamine-induced behaviour in Cebus apella monkeys
Brandt-Christensen, M., Andersen, M. B., Fink-Jensen, Anders, Werge, Thomas & Gerlach, J., 2006, In: Journal of Neural Transmission. 113, 1, p. 11-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Prenatal stress may increase vulnerability to life events: comparison with the effects of prenatal dexamethasone
Hougaard, Karin Sørig, Andersen, M. B., Kjaer, S. L., Hansen, Åse Marie, Werge, Thomas & Lund, S. P., 8 Sep 2005, In: Brain Research. 159, 1, p. 55-63 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of prenatal exposure to chronic mild stress and toluene in rats
Hougaard, Karin Sørig, Andersen, M. B., Hansen, Åse Marie, Hass, U., Werge, Thomas & Lund, S. P., 1 Feb 2005, In: Neurotoxicology and Teratology. 27, 1, p. 153-67 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the 120-bp duplication in the dopamine D4 receptor gene and schizophrenia in a sample of Danish subjects
Olsen, L., Timm, S., Wang, August Gabriel, Søeby, K., Jakobsen, K. D., Clemmensen, S., Løkke, A., Fossum, M., Parnas, Josef, Hemmingsen, R. P. A., Rasmussen, H. B. & Werge, Thomas, 2005, In: Schizophrenia Research. 73, 1, p. 133-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of prenatal exposure to chronic mild stress and toluene in rats
Hougaard, K., Andersen, M. B., Hansen, A. M., Hass, U., Werge, Thomas & Lund, S., 2005, In: Neurotoxicology and Teratology. 27, 1, p. 153-67 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genotyping of the 19-bp insertion/deletion polymorphism in the 5' flank of beta-hydroxylase gene by dissociation analysis of allele-specific PCR products
Rasmussen, H. B. & Werge, Thomas, 2005, In: Clinical Chemistry and Laboratory Medicine. 43, 9, p. 903-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of tandem repeats in exon III of dopamine receptor D4 (DRD4) genes from different mammalian species
Larsen, S. A., Mogensen, L., Dietz, R., Baagøe, H. J., Andersen, M., Werge, Thomas & Rasmussen, H. B., 2005, In: D N A and Cell Biology. 24, 12, p. 795-804 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal stress may increase vulnerability to life events comparison with the effects of prenatal dexamethasone
Hougaard, K., Andersen, M. B., Kjaer, S. L., Hansen, A. M., Werge, Thomas & Lund, S., 2005, In: Brain Research. 159, 1, p. 55-63 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reliability of clinical ICD-10 schizophrenia diagnoses
Jakobsen, K. D., Nordgaard, Julie , Hansen, T., Jansson, Lennart Bertil, Parnas, Josef & Werge, Thomas, 2005, In: Nordic Journal of Psychiatry. 59, 3, p. 209-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serotonin transporter evolution and impact of polymorphic transcriptional regulation
Søeby, K., Larsen, S. A., Olsen, L., Rasmussen, H. B. & Werge, Thomas, 2005, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 136B, 1, p. 53-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Effects of postnatal anoxia on striatal dopamine metabolism and prepulse inhibition in rats
Sandager-Nielsen, K., Andersen, M. B., Sager, T. N., Werge, Thomas & Scheel-Krüger, J., 2004, In: Pharmacology, Biochemistry and Behavior. 77, 4, p. 767-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Cholesterol-induced protein sorting: an analysis of energetic feasibility
Lundbaek, J. A., Andersen, Ove, Werge, Thomas & Nielsen, C., 2003, In: Biophysical Journal. 84, 3, p. 2080-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The muscarinic M1/M4 receptor agonist xanomeline exhibits antipsychotic-like activity in Cebus apella monkeys
Andersen, M. B., Fink-Jensen, Anders, Peacock, L., Gerlach, J., Bymaster, F., Lundbaek, J. A. & Werge, Thomas, 2003, In: Neuropsychopharmacology. 28, 6, p. 1168-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
The adenosine A2A receptor agonist CGS 21680 exhibits antipsychotic-like activity in Cebus apella monkeys
Andersen, M. B., Fuxe, K., Werge, Thomas & Gerlach, J., 2002, In: Behavioural Pharmacology. 13, 8, p. 639-44 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34394780
Most downloads
-
3096
downloads
Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
589
downloads
Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
340
downloads
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
Published