Alcohol intake and risk of non-Hodgkin lymphoma in men and women
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Alcohol intake and risk of non-Hodgkin lymphoma in men and women. / Chang, Ellen T.; Smedby, Karin Ekström; Zhang, Shumin M.; Hjalgrim, Henrik; Melbye, Mads; Öst, Åke; Wolk, Alicja; Adami, Hans Olov; Glimelius, Bengt.
I: Cancer Causes and Control, Bind 15, Nr. 10, 2004, s. 1067-1076.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Alcohol intake and risk of non-Hodgkin lymphoma in men and women
AU - Chang, Ellen T.
AU - Smedby, Karin Ekström
AU - Zhang, Shumin M.
AU - Hjalgrim, Henrik
AU - Melbye, Mads
AU - Öst, Åke
AU - Wolk, Alicja
AU - Adami, Hans Olov
AU - Glimelius, Bengt
PY - 2004
Y1 - 2004
N2 - Objective: The effect of alcohol intake on risk of NHL is unclear. We therefore conducted a population-based case-control study to examine the association between alcohol and NHL risk. Methods: 613 NHL cases and 480 population controls in Sweden reported their average consumption of beer, wine, and liquor 2 years before the study. Unconditional logistic regression was used to estimate the odds ratios (OR) and corresponding 95% confidence intervals (CI) for associations between alcohol intake and NHL risk. Results: Intake of total alcohol, beer, wine, or liquor was not associated with risk of overall NHL. There was no difference in risk of NHL among those who habitually consumed above 19.1 g of ethanol per day, compared to those who consumed on average 0-2.2 g of ethanol per day (OR = 1.2 (95% CI: 0.8, 1.7); ptrend = 0.29). However, the association was significantly positive among males (OR = 1.8 (95% CI: 1.1, 2.9); ptrend = 0.06). Total alcohol, beer, wine, or liquor intake was not associated with any major histopathologic subtype of NHL examined, apart from an association between high wine consumption and increased risk of chronic lymphocytic leukemia. Conclusions: Alcohol does not appear to be a major etiologic factor for overall NHL, nor its common subtypes.
AB - Objective: The effect of alcohol intake on risk of NHL is unclear. We therefore conducted a population-based case-control study to examine the association between alcohol and NHL risk. Methods: 613 NHL cases and 480 population controls in Sweden reported their average consumption of beer, wine, and liquor 2 years before the study. Unconditional logistic regression was used to estimate the odds ratios (OR) and corresponding 95% confidence intervals (CI) for associations between alcohol intake and NHL risk. Results: Intake of total alcohol, beer, wine, or liquor was not associated with risk of overall NHL. There was no difference in risk of NHL among those who habitually consumed above 19.1 g of ethanol per day, compared to those who consumed on average 0-2.2 g of ethanol per day (OR = 1.2 (95% CI: 0.8, 1.7); ptrend = 0.29). However, the association was significantly positive among males (OR = 1.8 (95% CI: 1.1, 2.9); ptrend = 0.06). Total alcohol, beer, wine, or liquor intake was not associated with any major histopathologic subtype of NHL examined, apart from an association between high wine consumption and increased risk of chronic lymphocytic leukemia. Conclusions: Alcohol does not appear to be a major etiologic factor for overall NHL, nor its common subtypes.
KW - Alcohol
KW - Epidemiology
KW - Non-Hodgkin lymphoma
UR - http://www.scopus.com/inward/record.url?scp=17844363478&partnerID=8YFLogxK
U2 - 10.1007/s10552-004-2234-2
DO - 10.1007/s10552-004-2234-2
M3 - Journal article
C2 - 15801490
AN - SCOPUS:17844363478
VL - 15
SP - 1067
EP - 1076
JO - Cancer Causes & Control
JF - Cancer Causes & Control
SN - 0957-5243
IS - 10
ER -
ID: 259461262