Cerebral net exchange of large neutral amino acids after lipopolysaccharide infusion in healthy humans
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Alterations in circulating large neutral amino acids (LNAAs), leading to a decrease in the plasma ratio between branched-chain and aromatic amino acids (BCAA/AAA ratio), may be involved in sepsis-associated encephalopathy. We hypothesised that a decrease in the BCAA/AAA ratio occurs along with a net cerebral influx of the neurotoxic AAA phenylalanine in a human experimental model of systemic inflammation.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Critical Care |
Vol/bind | 14 |
Udgave nummer | 1 |
Sider (fra-til) | R16 |
ISSN | 1574-4280 |
DOI | |
Status | Udgivet - 1 jan. 2010 |
ID: 34113389