Foodborne origin and local and global spread of staphylococcus saprophyticus causing human urinary tract infections

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Foodborne origin and local and global spread of staphylococcus saprophyticus causing human urinary tract infections. / Lawal, Opeyemi U.; Fraqueza, Maria J.; Bouchami, Ons; Worning, Peder; Bartels, Mette D.; Gonçalves, Maria L.; Paixao, Paulo; Gonçalves, Elsa; Toscano, Cristina; Empel, Joanna; Urbaś, Małgorzata; Domínguez, M. Angeles; Westh, Henrik; de Lencastre, Hermínia; Miragaia, Maria.

I: Emerging Infectious Diseases, Bind 27, Nr. 3, 2021, s. 880-893.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Lawal, OU, Fraqueza, MJ, Bouchami, O, Worning, P, Bartels, MD, Gonçalves, ML, Paixao, P, Gonçalves, E, Toscano, C, Empel, J, Urbaś, M, Domínguez, MA, Westh, H, de Lencastre, H & Miragaia, M 2021, 'Foodborne origin and local and global spread of staphylococcus saprophyticus causing human urinary tract infections', Emerging Infectious Diseases, bind 27, nr. 3, s. 880-893. https://doi.org/10.3201/eid2703.200852

APA

Lawal, O. U., Fraqueza, M. J., Bouchami, O., Worning, P., Bartels, M. D., Gonçalves, M. L., Paixao, P., Gonçalves, E., Toscano, C., Empel, J., Urbaś, M., Domínguez, M. A., Westh, H., de Lencastre, H., & Miragaia, M. (2021). Foodborne origin and local and global spread of staphylococcus saprophyticus causing human urinary tract infections. Emerging Infectious Diseases, 27(3), 880-893. https://doi.org/10.3201/eid2703.200852

Vancouver

Lawal OU, Fraqueza MJ, Bouchami O, Worning P, Bartels MD, Gonçalves ML o.a. Foodborne origin and local and global spread of staphylococcus saprophyticus causing human urinary tract infections. Emerging Infectious Diseases. 2021;27(3):880-893. https://doi.org/10.3201/eid2703.200852

Author

Lawal, Opeyemi U. ; Fraqueza, Maria J. ; Bouchami, Ons ; Worning, Peder ; Bartels, Mette D. ; Gonçalves, Maria L. ; Paixao, Paulo ; Gonçalves, Elsa ; Toscano, Cristina ; Empel, Joanna ; Urbaś, Małgorzata ; Domínguez, M. Angeles ; Westh, Henrik ; de Lencastre, Hermínia ; Miragaia, Maria. / Foodborne origin and local and global spread of staphylococcus saprophyticus causing human urinary tract infections. I: Emerging Infectious Diseases. 2021 ; Bind 27, Nr. 3. s. 880-893.

Bibtex

@article{5c9b83bdafbb4583835d53f6649a7bdf,
title = "Foodborne origin and local and global spread of staphylococcus saprophyticus causing human urinary tract infections",
abstract = "Staphylococcus saprophyticus is a primary cause of community-acquired urinary tract infections (UTIs) in young women. S. saprophyticus colonizes humans and animals but basic features of its molecular epidemiology are undetermined. We conducted a phylogenomic analysis of 321 S. saprophyticus isolates collected from human UTIs worldwide during 1997-2017 and 232 isolates from human UTIs and the pig-processing chain in a confined region during 2016-2017. We found epidemiologic and genomic evidence that the meat-production chain is a major source of S. saprophyticus causing human UTIs; human microbiota is another possible origin. Pathogenic S. saprophyticus belonged to 2 lineages with distinctive generic features that are globally and locally disseminated. Pangenome-wide approaches identified a strong association between pathogenicity and antimicrobial resistance, phages, platelet binding proteins, and an increased recombination rate. Our study provides insight into the origin, transmission, and population structure of pathogenic S. saprophyticus and identifies putative new virulence factors.",
author = "Lawal, {Opeyemi U.} and Fraqueza, {Maria J.} and Ons Bouchami and Peder Worning and Bartels, {Mette D.} and Gon{\c c}alves, {Maria L.} and Paulo Paixao and Elsa Gon{\c c}alves and Cristina Toscano and Joanna Empel and Ma{\l}gorzata Urba{\'s} and Dom{\'i}nguez, {M. Angeles} and Henrik Westh and {de Lencastre}, Herm{\'i}nia and Maria Miragaia",
note = "Publisher Copyright: {\textcopyright} 2021 Centers for Disease Control and Prevention (CDC). All rights reserved.",
year = "2021",
doi = "10.3201/eid2703.200852",
language = "English",
volume = "27",
pages = "880--893",
journal = "Emerging Infectious Diseases",
issn = "1080-6040",
publisher = "CDC Centers for Disease Control and Prevention",
number = "3",

}

RIS

TY - JOUR

T1 - Foodborne origin and local and global spread of staphylococcus saprophyticus causing human urinary tract infections

AU - Lawal, Opeyemi U.

AU - Fraqueza, Maria J.

AU - Bouchami, Ons

AU - Worning, Peder

AU - Bartels, Mette D.

AU - Gonçalves, Maria L.

AU - Paixao, Paulo

AU - Gonçalves, Elsa

AU - Toscano, Cristina

AU - Empel, Joanna

AU - Urbaś, Małgorzata

AU - Domínguez, M. Angeles

AU - Westh, Henrik

AU - de Lencastre, Hermínia

AU - Miragaia, Maria

N1 - Publisher Copyright: © 2021 Centers for Disease Control and Prevention (CDC). All rights reserved.

PY - 2021

Y1 - 2021

N2 - Staphylococcus saprophyticus is a primary cause of community-acquired urinary tract infections (UTIs) in young women. S. saprophyticus colonizes humans and animals but basic features of its molecular epidemiology are undetermined. We conducted a phylogenomic analysis of 321 S. saprophyticus isolates collected from human UTIs worldwide during 1997-2017 and 232 isolates from human UTIs and the pig-processing chain in a confined region during 2016-2017. We found epidemiologic and genomic evidence that the meat-production chain is a major source of S. saprophyticus causing human UTIs; human microbiota is another possible origin. Pathogenic S. saprophyticus belonged to 2 lineages with distinctive generic features that are globally and locally disseminated. Pangenome-wide approaches identified a strong association between pathogenicity and antimicrobial resistance, phages, platelet binding proteins, and an increased recombination rate. Our study provides insight into the origin, transmission, and population structure of pathogenic S. saprophyticus and identifies putative new virulence factors.

AB - Staphylococcus saprophyticus is a primary cause of community-acquired urinary tract infections (UTIs) in young women. S. saprophyticus colonizes humans and animals but basic features of its molecular epidemiology are undetermined. We conducted a phylogenomic analysis of 321 S. saprophyticus isolates collected from human UTIs worldwide during 1997-2017 and 232 isolates from human UTIs and the pig-processing chain in a confined region during 2016-2017. We found epidemiologic and genomic evidence that the meat-production chain is a major source of S. saprophyticus causing human UTIs; human microbiota is another possible origin. Pathogenic S. saprophyticus belonged to 2 lineages with distinctive generic features that are globally and locally disseminated. Pangenome-wide approaches identified a strong association between pathogenicity and antimicrobial resistance, phages, platelet binding proteins, and an increased recombination rate. Our study provides insight into the origin, transmission, and population structure of pathogenic S. saprophyticus and identifies putative new virulence factors.

U2 - 10.3201/eid2703.200852

DO - 10.3201/eid2703.200852

M3 - Journal article

C2 - 33622483

AN - SCOPUS:85101655624

VL - 27

SP - 880

EP - 893

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

SN - 1080-6040

IS - 3

ER -

ID: 297013764