Genetics of panic disorder on the Faroe Islands: a replication study of chromosome 9 and panic disorder
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Genetics of panic disorder on the Faroe Islands: a replication study of chromosome 9 and panic disorder. / Wang, August G; Dahl, Hans Atli; Vang, Maria; Als, Thomas Damm; Ewald, Henrik; Kruse, Torben A; Mors, Ole.
I: Psychiatric Genetics, Bind 16, Nr. 3, 2006, s. 99-104.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Genetics of panic disorder on the Faroe Islands: a replication study of chromosome 9 and panic disorder
AU - Wang, August G
AU - Dahl, Hans Atli
AU - Vang, Maria
AU - Als, Thomas Damm
AU - Ewald, Henrik
AU - Kruse, Torben A
AU - Mors, Ole
N1 - Keywords: Atlantic Islands; Chromosome Mapping; Chromosomes, Human, Pair 9; DNA Replication; Female; Genotype; Humans; Male; Panic Disorder; Pedigree; Risk Factors
PY - 2006
Y1 - 2006
N2 - OBJECTIVE: The population of the Faroe Islands in the North Atlantic Ocean is likely to have the same ancestry as the Icelandic population. An Icelandic study on Panic Disorder has found some evidence for a loci on chromosome 9. METHODS: On the Faroe Islands we have an ongoing genetic project concerning panic disorder among other psychiatric disorders. We searched for shared alleles and haplotypes in distantly related cases from the isolated and recently found population of the Faroe Islands, using 26 more or less evenly distributed microsatellite markers on chromosome 9, with emphasis on the candidate region identified in the Icelandic study. RESULTS: We have not been able to replicate the Icelandic results. Owing to the study design and sample size, we would not be able to detect areas with small impact.
AB - OBJECTIVE: The population of the Faroe Islands in the North Atlantic Ocean is likely to have the same ancestry as the Icelandic population. An Icelandic study on Panic Disorder has found some evidence for a loci on chromosome 9. METHODS: On the Faroe Islands we have an ongoing genetic project concerning panic disorder among other psychiatric disorders. We searched for shared alleles and haplotypes in distantly related cases from the isolated and recently found population of the Faroe Islands, using 26 more or less evenly distributed microsatellite markers on chromosome 9, with emphasis on the candidate region identified in the Icelandic study. RESULTS: We have not been able to replicate the Icelandic results. Owing to the study design and sample size, we would not be able to detect areas with small impact.
U2 - http://dx.doi.org/10.1097/01.ypg.0000199445.77291.ab
DO - http://dx.doi.org/10.1097/01.ypg.0000199445.77291.ab
M3 - Journal article
VL - 16
SP - 99
EP - 104
JO - Psychiatric Genetics
JF - Psychiatric Genetics
SN - 0955-8829
IS - 3
ER -
ID: 34119827