Changes in quality of life 6 months after parathyroidectomy for primary hyperparathyroidism
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Objective: The extent of symptoms due to primary hyperparathyroidism (PHPT) depends on the population being studied. PHPT is mainly discovered incidentally through routine laboratory findings. Less is known about patient-experienced improvement following successful parathyroidectomy. The aim of our study was to assess the changes in the quality of life (QoL) after successful surgery using an SF-36 questionnaire. Design: This is a prospective cohort study based on questionnaires. Methods: Forty consecutive patients diagnosed with PHPT were prospectively administered an SF-36 questionnaire before and 6 months after successful parathyroidectomy. A subgroup of 18 patients answered the questionnaire at 1 and 3 months after surgery. Successful surgery was based on biochemistry and pathology reports as confirmed by an endocrinologist. Results of each SF-36 subcategory were compared to the results at baseline in order to detect changes in patient-reported QoL after successful surgery. Results: There were significant improvements in six of eight SF-36 subcategories: vitality (P = 0.0001), physical functioning (P = 0.04), general health perception (P = 0.004), physical role functioning (P = 0.04), social role functioning (P = 0.004), and mental health perception (P = 0.0001). Changes appeared within a month after surgery with no further significant changes at later time points. Conclusions: Parathyroidectomy significantly improves QoL as measured by a decrease in SF-36 scores as early as 1 month after successful parathyroidectomy. The SF-36 QoL questionnaire is suitable for monitoring changes in patient well-being after successful parathyroidectomy.
Originalsprog | Engelsk |
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Artikelnummer | e210630 |
Tidsskrift | Endocrine Connections |
Vol/bind | 11 |
Udgave nummer | 3 |
ISSN | 2049-3614 |
DOI | |
Status | Udgivet - 2022 |
Bibliografisk note
Funding Information:
J W C received partial funding from the Scientific Committee of Herlev
Funding Information:
J W C received partial funding from the Scientific Committee of Herlev University Hospital.
Publisher Copyright:
© 2022 The authors.
ID: 313864485