International benchmarking in type 1 diabetes: Large difference in childhood HbA1c between eight high-income countries but similar rise during adolescence—A quality registry study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Dokumenter

  • Johan Anderzén
  • Julia M. Hermann
  • Ulf Samuelsson
  • Dimitrios Charalampopoulos
  • Torild Skrivarhaug
  • Elke Fröhlich-Reiterer
  • David M. Maahs
  • Karin Akesson
  • Thomas Kapellen
  • Maria Fritsch
  • Niels H. Birkebæk
  • Ann K. Drivvoll
  • Kellee Miller
  • Terence Stephenson
  • Sabine E. Hofer
  • Siri Fredheim
  • Siv J. Kummernes
  • Nicole Foster
  • Rakesh Amin
  • Dörte Hilgard
  • Birgit Rami-Merhar
  • Knut Dahl-Jørgensen
  • Mark Clements
  • Ragnar Hanas
  • Reinhard W. Holl
  • Justin T. Warner

Objectives: To identify differences and similarities in HbA1c levels and patterns regarding age and gender in eight high-income countries. Subjects: 66 071 children and adolescents below18 years of age with type 1 diabetes for at least 3 months and at least one HbA1c measurement during the study period. Methods: Pediatric Diabetes Quality Registry data from Austria, Denmark, England, Germany, Norway, Sweden, the United States, and Wales were collected between 2013 and 2014. HbA1c, gender, age, and duration were used in the analysis. Results: Distribution of gender and age groups was similar in the eight participating countries. The mean HbA1c varied from 60 to 73 mmol/mol (7.6%-8.8%) between the countries. The increase in HbA1c between the youngest (0-9 years) to the oldest (15-17 years) age group was close to 8 mmol/mol (0.7%) in all countries (P <.001). Females had a 1 mmol/mol (0.1%) higher mean HbA1c than boys (P <.001) in seven out of eight countries. Conclusions: In spite of large differences in the mean HbA1c between countries, a remarkable similarity in the increase of HbA1c from childhood to adolescence was found.

OriginalsprogEngelsk
TidsskriftPediatric Diabetes
Vol/bind21
Udgave nummer4
Sider (fra-til)621-627
Antal sider7
ISSN1399-543X
DOI
StatusUdgivet - 2020

Bibliografisk note

Funding Information:
The authors thank all the participating pediatric diabetes centers and all patients. Finally we also thank Lena Hanberger (RN, PhD, Link?ping University, Sweden) for her contribution to the manuscript. UCL Children's Policy Research Unit (CPRU) is funded by the England Department of Health Policy Research Programme (funding reference 10090001) and supported by the National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London. The views expressed are not necessarily those of the Department of Health. NPDA is funded by NHS England and the Welsh Government. NCDR is funded by the South-Eastern Norway Regional Health Authority. DanDiabKids is funded by the Health Research Fund of Central Denmark Region. SWEDIABKIDS is supported by Swedish Association of Local Authorities and Regions (SALAR). DPV is funded by the German Centre for Diabetes Research (FKZ: 82DZD01402), the German Diabetes Association (DDG), the European Foundation for the study of Diabetes (EFSD), and the EU-IMI2 consortium INNODIA. T1D Exchange is funded by the Helmsley Charitable Trust. The study was supported by Futurum Academy for Health and Care. Funding sources had no role in the study design, data collection, data analysis, data interpretation, or writing of the paper.

Funding Information:
England Department of Health Policy Research Programme; EU‐IMI2 consortium INNODIA; European Foundation for the Study of Diabetes; Futurum Academy for Health and Care; German Centre for Diabetes Research; German Diabetes Association; Health Research Fund of Central Denmark Region; Helmsley Charitable Trust; National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London; NHS England and the Welsh Government; South‐Eastern Norway Regional Health Authority; Swedish Association of Local Authorities and Regions (SALAR) Funding information

Funding Information:
The authors thank all the participating pediatric diabetes centers and all patients. Finally we also thank Lena Hanberger (RN, PhD, Linköping University, Sweden) for her contribution to the manuscript. UCL Children's Policy Research Unit (CPRU) is funded by the England Department of Health Policy Research Programme (funding reference 10090001) and supported by the National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London. The views expressed are not necessarily those of the Department of Health. NPDA is funded by NHS England and the Welsh Government. NCDR is funded by the South‐Eastern Norway Regional Health Authority. DanDiabKids is funded by the Health Research Fund of Central Denmark Region. SWEDIABKIDS is supported by Swedish Association of Local Authorities and Regions (SALAR). DPV is funded by the German Centre for Diabetes Research (FKZ: 82DZD01402), the German Diabetes Association (DDG), the European Foundation for the study of Diabetes (EFSD), and the EU‐IMI2 consortium INNODIA. T1D Exchange is funded by the Helmsley Charitable Trust. The study was supported by Futurum Academy for Health and Care. Funding sources had no role in the study design, data collection, data analysis, data interpretation, or writing of the paper.

Publisher Copyright:
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

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