The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action

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  • Eloi Marijon
  • Kumar Narayanan
  • Karen Smith
  • Sérgio Barra
  • Cristina Basso
  • Marieke T. Blom
  • Lia Crotti
  • Andre D'Avila
  • Rajat Deo
  • Florence Dumas
  • Anastase Dzudie
  • Audrey Farrugia
  • Kaitlyn Greeley
  • Gerhard Hindricks
  • Wei Hua
  • Jodie Ingles
  • Taku Iwami
  • Juhani Junttila
  • Rudolph W. Koster
  • Jean Benoît Le Polain De Waroux
  • Theresa M. Olasveengen
  • Marcus E. H. Ong
  • Michael Papadakis
  • Comilla Sasson
  • Sang Do Shin
  • Hung-Fat Tse
  • Zian Tseng
  • Christian Van Der Werf
  • Christine M. Albert
  • Bo Gregers Winkel

Despite major advancements in cardiovascular medicine, sudden cardiac death (SCD) continues to be an enormous medical and societal challenge, claiming millions of lives every year. Efforts to prevent SCD are hampered by imperfect risk prediction and inadequate solutions to specifically address arrhythmogenesis. Although resuscitation strategies have witnessed substantial evolution, there is a need to strengthen the organisation of community interventions and emergency medical systems across varied locations and health-care structures. With all the technological and medical advances of the 21st century, the fact that survival from sudden cardiac arrest (SCA) remains lower than 10% in most parts of the world is unacceptable. Recognising this urgent need, the Lancet Commission on SCD was constituted, bringing together 30 international experts in varied disciplines. Consistent progress in tackling SCD will require a completely revamped approach to SCD prevention, with wide-sweeping policy changes that will empower the development of both governmental and community-based programmes to maximise survival from SCA, and to comprehensively attend to survivors and decedents’ families after the event. International collaborative efforts that maximally leverage and connect the expertise of various research organisations will need to be prioritised to properly address identified gaps. The Commission places substantial emphasis on the need to develop a multidisciplinary strategy that encompasses all aspects of SCD prevention and treatment. The Commission provides a critical assessment of the current scientific efforts in the field, and puts forth key recommendations to challenge, activate, and intensify efforts by both the scientific and global community with new directions, research, and innovation to reduce the burden of SCD worldwide.

TidsskriftThe Lancet
Udgave nummer10405
Sider (fra-til)883-936
Antal sider54
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
We thank the Paris-Sudden Death Expertise Center (Paris-SDEC), the French Federation of Cardiology, the French Society of Cardiology, l'Association Française d’Epargne et de Retraite, the Foundation Medical Research Institutes, and the Paris Artificial Intelligence Research Institute (PRAIRIE) for their financial contributions and support of the various meetings throughout the Commission. We also thank the industrial partners (Abbott, Biotronik, Boston Scientific, Medtronic, MicroPort, Zoll, and Schiller) for the unrestricted grants supporting Paris-SDEC activities. We thank Nicole Karam and Antoine Lafont of the Division of Cardiology, European Hospital Georges Pompidou, Paris, for their help in the process of publishing this collaborative document.

Publisher Copyright:
© 2023 Elsevier Ltd

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