Percutaneous penetration characteristics and release kinetics of contact allergens encapsulated in ethosomes
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Formulation of the contact allergens dinitrochlorobenzene and isoeugenol in ethanolic liposomes (ethosomes) increases their sensitizing properties in the local lymph node assay compared with an ethanol-water formulation of the allergens. Likewise, isoeugenol and methyldibromo-glutaronitrile formulated in ethosomes enhanced the patch test reactions in sensitized human volunteers. The relationship between the percutaneous penetration/absorption and sensitization/elicitation phases of contact allergy is not well elucidated.
Originalsprog | Engelsk |
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Tidsskrift | Cutaneous and Ocular Toxicology |
Vol/bind | 30 |
Udgave nummer | 1 |
Sider (fra-til) | 38-44 |
Antal sider | 7 |
ISSN | 1556-9527 |
DOI | |
Status | Udgivet - 1 mar. 2011 |
ID: 40166298