Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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The gut microbiome has increasingly been recognized as a critical and central factor in inflammatory bowel disease (IBD). Here, we review specific microorganisms that have been suggested to play a role in the pathogenesis of IBD and the current state of fecal microbial transplants as a therapeutic strategy in IBD. We discuss specific nutritional and dietary interventions in IBD and their effects on gut microbiota composition. Finally, we examine the role and mechanisms of the gut microbiome in mediating colitis-associated colon cancer.
Originalsprog | Engelsk |
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Artikelnummer | 1371 |
Tidsskrift | Microorganisms |
Vol/bind | 10 |
Udgave nummer | 7 |
ISSN | 2076-2607 |
DOI | |
Status | Udgivet - 2022 |
Bibliografisk note
Funding Information:
Funding: JG is in part supported by a Chan Zuckerberg Biohub Physician Scientist Scholar Award, NIH NIDDK LRP Award (L30 DK126220), and a Doris Duke Physician Scientist Fellowship Award (Grant #2021091).
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
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