Forebyggelse af reaktivering af hepatitis B og hepatitis C ved immunsupprimerende behandling
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Forebyggelse af reaktivering af hepatitis B og hepatitis C ved immunsupprimerende behandling. / Risum, Malene; Barfod, Toke Seierøe.
I: Ugeskrift for Laeger, Bind 181, V08180568, 2019.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Forebyggelse af reaktivering af hepatitis B og hepatitis C ved immunsupprimerende behandling
AU - Risum, Malene
AU - Barfod, Toke Seierøe
PY - 2019
Y1 - 2019
N2 - The use of immunosuppressive agents can be vital. However, immunosuppression may also cause reactivation of hepatitis B virus (HBV) infection which can be fatal. To reduce the risk of reactivation prophylactic antiviral treatment is recommended in patients with chronic HBV infection. In patients with former HBV infection prophylaxis is also recommended if anti-CD20 agents are used and in cases of transplantation. Immunosuppression in patients with hepatitis C virus (HCV) infection does not seem to lead to severe hepatic manifestations, and reactivation of HCV in this context generally has a mild clinical course.
AB - The use of immunosuppressive agents can be vital. However, immunosuppression may also cause reactivation of hepatitis B virus (HBV) infection which can be fatal. To reduce the risk of reactivation prophylactic antiviral treatment is recommended in patients with chronic HBV infection. In patients with former HBV infection prophylaxis is also recommended if anti-CD20 agents are used and in cases of transplantation. Immunosuppression in patients with hepatitis C virus (HCV) infection does not seem to lead to severe hepatic manifestations, and reactivation of HCV in this context generally has a mild clinical course.
KW - Antiviral Agents
KW - Hepacivirus
KW - Hepatitis B/immunology
KW - Hepatitis B virus
KW - Hepatitis C/immunology
KW - Humans
KW - Immunosuppressive Agents/adverse effects
KW - Virus Activation
M3 - Tidsskriftartikel
C2 - 30729919
VL - 181
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
M1 - V08180568
ER -
ID: 240953190