Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction

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Standard

Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction. / Jørgensen, Anders Berg; Frikke-Schmidt, Ruth; West, Anders Sode; Grande, Peer; Nordestgaard, Børge G; Tybjærg-Hansen, Anne.

I: European Heart Journal, 2012.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Jørgensen, AB, Frikke-Schmidt, R, West, AS, Grande, P, Nordestgaard, BG & Tybjærg-Hansen, A 2012, 'Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction', European Heart Journal. https://doi.org/10.1093/eurheartj/ehs431

APA

Jørgensen, A. B., Frikke-Schmidt, R., West, A. S., Grande, P., Nordestgaard, B. G., & Tybjærg-Hansen, A. (2012). Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction. European Heart Journal. https://doi.org/10.1093/eurheartj/ehs431

Vancouver

Jørgensen AB, Frikke-Schmidt R, West AS, Grande P, Nordestgaard BG, Tybjærg-Hansen A. Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction. European Heart Journal. 2012. https://doi.org/10.1093/eurheartj/ehs431

Author

Jørgensen, Anders Berg ; Frikke-Schmidt, Ruth ; West, Anders Sode ; Grande, Peer ; Nordestgaard, Børge G ; Tybjærg-Hansen, Anne. / Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction. I: European Heart Journal. 2012.

Bibtex

@article{fbabba48037646eeb65d7078cc0d8f03,
title = "Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction",
abstract = "AimsElevated non-fasting triglycerides mark elevated levels of remnant cholesterol. Using a Mendelian randomization approach, we tested whether genetically increased remnant cholesterol in hypertriglyceridaemia due to genetic variation in the apolipoprotein A5 gene (APOA5) associates with an increased risk of myocardial infarction (MI).Methods and resultsWe resequenced the core promoter and coding regions of APOA5 in individuals with the lowest 1% (n = 95) and highest 2% (n = 190) triglyceride levels in the Copenhagen City Heart Study (CCHS, n = 10 391). Genetic variants which differed in frequency between the two extreme triglyceride groups (c.-1131T > C, S19W, and c.*31C > T; P-value: 0.06 to",
author = "J{\o}rgensen, {Anders Berg} and Ruth Frikke-Schmidt and West, {Anders Sode} and Peer Grande and Nordestgaard, {B{\o}rge G} and Anne Tybj{\ae}rg-Hansen",
year = "2012",
doi = "10.1093/eurheartj/ehs431",
language = "English",
journal = "European Heart Journal",
issn = "0195-668X",
publisher = "Oxford University Press",

}

RIS

TY - JOUR

T1 - Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction

AU - Jørgensen, Anders Berg

AU - Frikke-Schmidt, Ruth

AU - West, Anders Sode

AU - Grande, Peer

AU - Nordestgaard, Børge G

AU - Tybjærg-Hansen, Anne

PY - 2012

Y1 - 2012

N2 - AimsElevated non-fasting triglycerides mark elevated levels of remnant cholesterol. Using a Mendelian randomization approach, we tested whether genetically increased remnant cholesterol in hypertriglyceridaemia due to genetic variation in the apolipoprotein A5 gene (APOA5) associates with an increased risk of myocardial infarction (MI).Methods and resultsWe resequenced the core promoter and coding regions of APOA5 in individuals with the lowest 1% (n = 95) and highest 2% (n = 190) triglyceride levels in the Copenhagen City Heart Study (CCHS, n = 10 391). Genetic variants which differed in frequency between the two extreme triglyceride groups (c.-1131T > C, S19W, and c.*31C > T; P-value: 0.06 to

AB - AimsElevated non-fasting triglycerides mark elevated levels of remnant cholesterol. Using a Mendelian randomization approach, we tested whether genetically increased remnant cholesterol in hypertriglyceridaemia due to genetic variation in the apolipoprotein A5 gene (APOA5) associates with an increased risk of myocardial infarction (MI).Methods and resultsWe resequenced the core promoter and coding regions of APOA5 in individuals with the lowest 1% (n = 95) and highest 2% (n = 190) triglyceride levels in the Copenhagen City Heart Study (CCHS, n = 10 391). Genetic variants which differed in frequency between the two extreme triglyceride groups (c.-1131T > C, S19W, and c.*31C > T; P-value: 0.06 to

U2 - 10.1093/eurheartj/ehs431

DO - 10.1093/eurheartj/ehs431

M3 - Journal article

C2 - 23248205

JO - European Heart Journal

JF - European Heart Journal

SN - 0195-668X

ER -

ID: 48456446