Genetisk variation i alkoholdehydrogenase, alkoholdrikkevaner og alkoholisme--sekundaerpublikation
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Genetisk variation i alkoholdehydrogenase, alkoholdrikkevaner og alkoholisme--sekundaerpublikation. / Tolstrup, J.S.; Nordestgaard, B.G.; Rasmussen, S.; Tybjaerg-Hansen, A.; Gronbaek, M.
I: Ugeskrift for læger, Bind 170, Nr. 35, 2008, s. 2672-2675.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Genetisk variation i alkoholdehydrogenase, alkoholdrikkevaner og alkoholisme--sekundaerpublikation
AU - Tolstrup, J.S.
AU - Nordestgaard, B.G.
AU - Rasmussen, S.
AU - Tybjaerg-Hansen, A.
AU - Gronbaek, M.
PY - 2008
Y1 - 2008
N2 - Alcohol is degraded primarily by alcohol dehydrogenase (ADH), and genetic variation that affects the rate of alcohol degradation is found in ADH1B and ADH1C. By genotyping 9,080 white men and women from the general population, we found that men and women with ADH1B slow versus fast alcohol degradation drank approximately 30% more alcohol per week and had a higher risk of everyday and heavy drinking, and of alcoholism. Individuals with ADH1C slow versus fast alcohol degradation had a higher risk of heavy drinking Udgivelsesdato: 2008/8/25
AB - Alcohol is degraded primarily by alcohol dehydrogenase (ADH), and genetic variation that affects the rate of alcohol degradation is found in ADH1B and ADH1C. By genotyping 9,080 white men and women from the general population, we found that men and women with ADH1B slow versus fast alcohol degradation drank approximately 30% more alcohol per week and had a higher risk of everyday and heavy drinking, and of alcoholism. Individuals with ADH1C slow versus fast alcohol degradation had a higher risk of heavy drinking Udgivelsesdato: 2008/8/25
M3 - Tidsskriftartikel
VL - 170
SP - 2672
EP - 2675
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 35
ER -
ID: 10948591