Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer: A Prospective Cohort Study

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Standard

Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer : A Prospective Cohort Study. / Afzal, Shoaib; Nordestgaard, Børge G; Bojesen, Stig E.

I: Journal of Investigative Dermatology, Bind 133, 2013, s. 629-636.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Afzal, S, Nordestgaard, BG & Bojesen, SE 2013, 'Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer: A Prospective Cohort Study', Journal of Investigative Dermatology, bind 133, s. 629-636. https://doi.org/10.1038/jid.2012.395

APA

Afzal, S., Nordestgaard, B. G., & Bojesen, S. E. (2013). Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer: A Prospective Cohort Study. Journal of Investigative Dermatology, 133, 629-636. https://doi.org/10.1038/jid.2012.395

Vancouver

Afzal S, Nordestgaard BG, Bojesen SE. Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer: A Prospective Cohort Study. Journal of Investigative Dermatology. 2013;133:629-636. https://doi.org/10.1038/jid.2012.395

Author

Afzal, Shoaib ; Nordestgaard, Børge G ; Bojesen, Stig E. / Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer : A Prospective Cohort Study. I: Journal of Investigative Dermatology. 2013 ; Bind 133. s. 629-636.

Bibtex

@article{08eb6c60fe2447c4ba85a8a8fa1dd06f,
title = "Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer: A Prospective Cohort Study",
abstract = "Sun exposure is a major risk factor for skin cancer and is also an important source of vitamin D. We tested the hypothesis that elevated plasma 25-hydroxyvitamin D (25-OH-vitD) associates with increased risk of non-melanoma and melanoma skin cancer in the general population. We measured plasma 25-OH-vitD in 10,060 white individuals from the Danish general population. During 28 years of follow-up, 590 individuals developed non-melanoma skin cancer and 78 developed melanoma skin cancer. Increasing 25-OH-vitD levels, by clinical categories or by seasonally adjusted tertiles, were associated with increasing cumulative incidence of non-melanoma skin cancer (trend P=2 × 10(-15) and P=3 × 10(-17)) and melanoma skin cancer (P=0.003 and P=0.001). Multivariable adjusted hazard ratios of non-melanoma skin cancer were 5.04 (95% confidence interval (CI): 2.78-9.16) for 25-OH-vitD 50 vs. 60 years, 25-OH-vitD winter levels 50 nmol l(-1), and performing outdoor exercise. In conclusion, we show that increasing levels of 25-OH-vitD are associated with increased risk of non-melanoma and melanoma skin cancer.Journal of Investigative Dermatology advance online publication, 29 November 2012; doi:10.1038/jid.2012.395.",
author = "Shoaib Afzal and Nordestgaard, {B{\o}rge G} and Bojesen, {Stig E}",
year = "2013",
doi = "10.1038/jid.2012.395",
language = "English",
volume = "133",
pages = "629--636",
journal = "Journal of Investigative Dermatology",
issn = "0022-202X",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - Plasma 25-Hydroxyvitamin D and Risk of Non-Melanoma and Melanoma Skin Cancer

T2 - A Prospective Cohort Study

AU - Afzal, Shoaib

AU - Nordestgaard, Børge G

AU - Bojesen, Stig E

PY - 2013

Y1 - 2013

N2 - Sun exposure is a major risk factor for skin cancer and is also an important source of vitamin D. We tested the hypothesis that elevated plasma 25-hydroxyvitamin D (25-OH-vitD) associates with increased risk of non-melanoma and melanoma skin cancer in the general population. We measured plasma 25-OH-vitD in 10,060 white individuals from the Danish general population. During 28 years of follow-up, 590 individuals developed non-melanoma skin cancer and 78 developed melanoma skin cancer. Increasing 25-OH-vitD levels, by clinical categories or by seasonally adjusted tertiles, were associated with increasing cumulative incidence of non-melanoma skin cancer (trend P=2 × 10(-15) and P=3 × 10(-17)) and melanoma skin cancer (P=0.003 and P=0.001). Multivariable adjusted hazard ratios of non-melanoma skin cancer were 5.04 (95% confidence interval (CI): 2.78-9.16) for 25-OH-vitD 50 vs. 60 years, 25-OH-vitD winter levels 50 nmol l(-1), and performing outdoor exercise. In conclusion, we show that increasing levels of 25-OH-vitD are associated with increased risk of non-melanoma and melanoma skin cancer.Journal of Investigative Dermatology advance online publication, 29 November 2012; doi:10.1038/jid.2012.395.

AB - Sun exposure is a major risk factor for skin cancer and is also an important source of vitamin D. We tested the hypothesis that elevated plasma 25-hydroxyvitamin D (25-OH-vitD) associates with increased risk of non-melanoma and melanoma skin cancer in the general population. We measured plasma 25-OH-vitD in 10,060 white individuals from the Danish general population. During 28 years of follow-up, 590 individuals developed non-melanoma skin cancer and 78 developed melanoma skin cancer. Increasing 25-OH-vitD levels, by clinical categories or by seasonally adjusted tertiles, were associated with increasing cumulative incidence of non-melanoma skin cancer (trend P=2 × 10(-15) and P=3 × 10(-17)) and melanoma skin cancer (P=0.003 and P=0.001). Multivariable adjusted hazard ratios of non-melanoma skin cancer were 5.04 (95% confidence interval (CI): 2.78-9.16) for 25-OH-vitD 50 vs. 60 years, 25-OH-vitD winter levels 50 nmol l(-1), and performing outdoor exercise. In conclusion, we show that increasing levels of 25-OH-vitD are associated with increased risk of non-melanoma and melanoma skin cancer.Journal of Investigative Dermatology advance online publication, 29 November 2012; doi:10.1038/jid.2012.395.

U2 - 10.1038/jid.2012.395

DO - 10.1038/jid.2012.395

M3 - Journal article

C2 - 23190899

VL - 133

SP - 629

EP - 636

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

SN - 0022-202X

ER -

ID: 48539981