European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND). / Düzel, Emrah; Acosta-Cabronero, Julio; Berron, David; Biessels, Geert Jan; Björkman-Burtscher, Isabella; Bottlaender, Michel; Bowtell, Richard; Buchem, Mark V; Cardenas-Blanco, Arturo; Boumezbeur, Fawzi; Chan, Dennis; Clare, Stuart; Costagli, Mauro; de Rochefort, Ludovic; Fillmer, Ariane; Gowland, Penny; Hansson, Oskar; Hendrikse, Jeroen; Kraff, Oliver; Ladd, Mark E; Ronen, Itamar; Petersen, Esben; Rowe, James B; Siebner, Hartwig; Stoecker, Tony; Straub, Sina; Tosetti, Michela; Uludag, Kamil; Vignaud, Alexandre; Zwanenburg, Jaco; Speck, Oliver.
I: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, Bind 11, Nr. 1, 12.2019, s. 538-549.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)
AU - Düzel, Emrah
AU - Acosta-Cabronero, Julio
AU - Berron, David
AU - Biessels, Geert Jan
AU - Björkman-Burtscher, Isabella
AU - Bottlaender, Michel
AU - Bowtell, Richard
AU - Buchem, Mark V
AU - Cardenas-Blanco, Arturo
AU - Boumezbeur, Fawzi
AU - Chan, Dennis
AU - Clare, Stuart
AU - Costagli, Mauro
AU - de Rochefort, Ludovic
AU - Fillmer, Ariane
AU - Gowland, Penny
AU - Hansson, Oskar
AU - Hendrikse, Jeroen
AU - Kraff, Oliver
AU - Ladd, Mark E
AU - Ronen, Itamar
AU - Petersen, Esben
AU - Rowe, James B
AU - Siebner, Hartwig
AU - Stoecker, Tony
AU - Straub, Sina
AU - Tosetti, Michela
AU - Uludag, Kamil
AU - Vignaud, Alexandre
AU - Zwanenburg, Jaco
AU - Speck, Oliver
PY - 2019/12
Y1 - 2019/12
N2 - Introduction: The goal of European Ultrahigh-Field Imaging Network in Neurodegenerative Diseases (EUFIND) is to identify opportunities and challenges of 7 Tesla (7T) MRI for clinical and research applications in neurodegeneration. EUFIND comprises 22 European and one US site, including over 50 MRI and dementia experts as well as neuroscientists.Methods: EUFIND combined consensus workshops and data sharing for multisite analysis, focusing on 7 core topics: clinical applications/clinical research, highest resolution anatomy, functional imaging, vascular systems/vascular pathology, iron mapping and neuropathology detection, spectroscopy, and quality assurance. Across these topics, EUFIND considered standard operating procedures, safety, and multivendor harmonization.Results: The clinical and research opportunities and challenges of 7T MRI in each subtopic are set out as a roadmap. Specific MRI sequences for each subtopic were implemented in a pilot study presented in this report. Results show that a large multisite 7T imaging network with highly advanced and harmonized imaging sequences is feasible and may enable future multicentre ultrahigh-field MRI studies and clinical trials.Discussion: The EUFIND network can be a major driver for advancing clinical neuroimaging research using 7T and for identifying use-cases for clinical applications in neurodegeneration.
AB - Introduction: The goal of European Ultrahigh-Field Imaging Network in Neurodegenerative Diseases (EUFIND) is to identify opportunities and challenges of 7 Tesla (7T) MRI for clinical and research applications in neurodegeneration. EUFIND comprises 22 European and one US site, including over 50 MRI and dementia experts as well as neuroscientists.Methods: EUFIND combined consensus workshops and data sharing for multisite analysis, focusing on 7 core topics: clinical applications/clinical research, highest resolution anatomy, functional imaging, vascular systems/vascular pathology, iron mapping and neuropathology detection, spectroscopy, and quality assurance. Across these topics, EUFIND considered standard operating procedures, safety, and multivendor harmonization.Results: The clinical and research opportunities and challenges of 7T MRI in each subtopic are set out as a roadmap. Specific MRI sequences for each subtopic were implemented in a pilot study presented in this report. Results show that a large multisite 7T imaging network with highly advanced and harmonized imaging sequences is feasible and may enable future multicentre ultrahigh-field MRI studies and clinical trials.Discussion: The EUFIND network can be a major driver for advancing clinical neuroimaging research using 7T and for identifying use-cases for clinical applications in neurodegeneration.
U2 - 10.1016/j.dadm.2019.04.010
DO - 10.1016/j.dadm.2019.04.010
M3 - Journal article
C2 - 31388558
VL - 11
SP - 538
EP - 549
JO - Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
JF - Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
SN - 2352-8729
IS - 1
ER -
ID: 237416132