Ischemic Stroke Severity and Mortality in Patients With and Without Atrial Fibrillation
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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Ischemic Stroke Severity and Mortality in Patients With and Without Atrial Fibrillation. / Vinding, Naja E.; Kristensen, Soren L.; Rorth, Rasmus; Butt, Jawad H.; Ostergaard, Lauge; Olesen, Jonas B.; Torp-Pedersen, Christian; Gislason, Gunnar H.; Kober, Lars; Kruuse, Christina; Johnsen, Soren P.; Fosbol, Emil L.
I: Journal of the American Heart Association, Bind 11, Nr. 4, 022638, 15.02.2022.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Ischemic Stroke Severity and Mortality in Patients With and Without Atrial Fibrillation
AU - Vinding, Naja E.
AU - Kristensen, Soren L.
AU - Rorth, Rasmus
AU - Butt, Jawad H.
AU - Ostergaard, Lauge
AU - Olesen, Jonas B.
AU - Torp-Pedersen, Christian
AU - Gislason, Gunnar H.
AU - Kober, Lars
AU - Kruuse, Christina
AU - Johnsen, Soren P.
AU - Fosbol, Emil L.
PY - 2022/2/15
Y1 - 2022/2/15
N2 - Background Our objective was to investigate stroke severity and subsequent rate of mortality among patients with and without atrial fibrillation (AF). Contemporary data on stroke severity and prognosis in patients with AF are lacking. Methods and Results First-time ischemic stroke patients from the Danish Stroke Registry (January 2005-December 2016) were included in an observational study. Patients with AF were matched 1:1 by sex, age, calendar year, and CHA(2)DS(2)-VASc score with patients without AF. Stroke severity was determined by the Scandinavian Stroke Scale (0-58 points). The rate of death was estimated by Kaplan-Meier plots and multivariable Cox regression. Among 86 458 identified patients with stroke, 17 205 had AF. After matching, 14 662 patients with AF and 14 662 patients without AF were included (51.8% women; median age, 79.6 years [25th-75th percentile, 71.8-86.0]). More patients with AF had very severe stroke (0-14 points) than patients without AF (13.7% versus 7.9%, P
AB - Background Our objective was to investigate stroke severity and subsequent rate of mortality among patients with and without atrial fibrillation (AF). Contemporary data on stroke severity and prognosis in patients with AF are lacking. Methods and Results First-time ischemic stroke patients from the Danish Stroke Registry (January 2005-December 2016) were included in an observational study. Patients with AF were matched 1:1 by sex, age, calendar year, and CHA(2)DS(2)-VASc score with patients without AF. Stroke severity was determined by the Scandinavian Stroke Scale (0-58 points). The rate of death was estimated by Kaplan-Meier plots and multivariable Cox regression. Among 86 458 identified patients with stroke, 17 205 had AF. After matching, 14 662 patients with AF and 14 662 patients without AF were included (51.8% women; median age, 79.6 years [25th-75th percentile, 71.8-86.0]). More patients with AF had very severe stroke (0-14 points) than patients without AF (13.7% versus 7.9%, P
KW - atrial fibrillation
KW - epidemiology
KW - ischemic stroke
KW - severity
KW - stroke severity
KW - ESC GUIDELINES
KW - MANAGEMENT
KW - VALIDITY
KW - REGISTRY
KW - RELIABILITY
KW - DEATH
KW - SCALE
KW - SCORE
U2 - 10.1161/JAHA.121.022638
DO - 10.1161/JAHA.121.022638
M3 - Journal article
C2 - 35156393
VL - 11
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
SN - 2047-9980
IS - 4
M1 - 022638
ER -
ID: 314153128