Days alive and out of hospital following transoral robotic surgery: Cohort study of 262 patients with head and neck cancer
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Days alive and out of hospital following transoral robotic surgery : Cohort study of 262 patients with head and neck cancer. / Larsen, Mikkel H.H.; Scott, Susanne I.; Channir, Hani I.; Madsen, Anne K.Ø.; Charabi, Birgitte W.; Rubek, Niclas; Tvedskov, Jesper F.; Kehlet, Henrik; von Buchwald, Christian.
I: Head and Neck, Bind 43, Nr. 12, 2021, s. 3866-3874.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Days alive and out of hospital following transoral robotic surgery
T2 - Cohort study of 262 patients with head and neck cancer
AU - Larsen, Mikkel H.H.
AU - Scott, Susanne I.
AU - Channir, Hani I.
AU - Madsen, Anne K.Ø.
AU - Charabi, Birgitte W.
AU - Rubek, Niclas
AU - Tvedskov, Jesper F.
AU - Kehlet, Henrik
AU - von Buchwald, Christian
N1 - Funding Information: Candys Foundation, Grant/Award Number: 2019-304; Doctor Fritz Karner and Wife's Foundation; Region Hovedstaden, Grant/Award Number: A6682 Publisher Copyright: © 2021 Wiley Periodicals LLC.
PY - 2021
Y1 - 2021
N2 - Background: Days alive and out of hospital (DAOH) is a validated outcome in clinical trials, since it reflects procedure-associated morbidity and mortality. Transoral robotic surgery (TORS) has become a widely adopted procedure with increasing demand for knowledge and data on morbidity. Methods: Retrospective single-center assessment of a prospective TORS database comprising patients treated for malignancy between 2013 and 2018 using DAOH to describe procedure- and disease-related morbidity the first 12-postoperative months. Results: For 262 patients, median DAOH365 was 357 days (IQR 351–360). Indications for TORS were (i) primary curative resection (61%), (ii) salvage resection (15%), and (iii) diagnostic work-up of cancer of unknown primary in the head and neck (24%). Median DAOH365 was 359 days (IQR 351–361 days), 348 days (IQR 233–355), and 357 days (351–361), respectively. Pneumonia had the highest impact in DAOH365 reduction. Conclusion: Total median DAOH365 after TORS was 357 days. The main cause leading to DAOH365 reduction was pneumonia.
AB - Background: Days alive and out of hospital (DAOH) is a validated outcome in clinical trials, since it reflects procedure-associated morbidity and mortality. Transoral robotic surgery (TORS) has become a widely adopted procedure with increasing demand for knowledge and data on morbidity. Methods: Retrospective single-center assessment of a prospective TORS database comprising patients treated for malignancy between 2013 and 2018 using DAOH to describe procedure- and disease-related morbidity the first 12-postoperative months. Results: For 262 patients, median DAOH365 was 357 days (IQR 351–360). Indications for TORS were (i) primary curative resection (61%), (ii) salvage resection (15%), and (iii) diagnostic work-up of cancer of unknown primary in the head and neck (24%). Median DAOH365 was 359 days (IQR 351–361 days), 348 days (IQR 233–355), and 357 days (351–361), respectively. Pneumonia had the highest impact in DAOH365 reduction. Conclusion: Total median DAOH365 after TORS was 357 days. The main cause leading to DAOH365 reduction was pneumonia.
KW - cancer
KW - morbidity
KW - perioperative medicine
KW - postoperative outcomes
KW - surgery
U2 - 10.1002/hed.26880
DO - 10.1002/hed.26880
M3 - Journal article
C2 - 34605110
AN - SCOPUS:85116154156
VL - 43
SP - 3866
EP - 3874
JO - Head & Neck (Print Edition)
JF - Head & Neck (Print Edition)
SN - 1043-3074
IS - 12
ER -
ID: 302069372