A letter to the editor: The effects of alcohol use on brain glutamate in first episode psychosis

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

  • Bridget King
  • Matthew J. Kempton
  • Brian V. Broberg
  • Kate Merritt
  • Gareth J. Barker
  • David J. Lythgoe
  • Rocio Perez-Iglesias
  • Baandrup, Lone
  • Signe W. Düring
  • James M. Stone
  • Rostrup, Egill
  • Iris E. Sommer
  • Glenthøj, Birte Yding
  • René S. Kahn
  • Paola Dazzan
  • Philip K. McGuire
  • Alice Egerton
Alcohol use in schizophrenia is associated with poorer outcomes, such as increased suicidality and positive symptoms (Lv et al., 2023). Both alcohol use and psychosis have been independently associated with changes in brain glutamate levels. However, whether alcohol use impacts brain glutamate levels in people with psychosis is unknown. Potentially, overlapping glutamatergic pathophysiology could mean that, patients with schizophrenia are more vulnerable to the effects of alcohol.
OriginalsprogEngelsk
TidsskriftSchizophrenia Research
Vol/bind266
Sider (fra-til)234-236
Antal sider3
ISSN0920-9964
DOI
StatusUdgivet - 2024

Bibliografisk note

Funding Information:
In the last 3 years, J.M.S. has been principal investigator or sub-investigator on studies sponsored by Takeda, Janssen and Lundbeck Plc. During study conduct and data collection, B.B was employed at Mental Health Services, Capital Region of Denmark, University of Copenhagen, Glostrup, Denmark. B.B is currently employed by H.Lundbeck A/S and has not been directly involved in the data analysis, but reviewed the manuscript. B.G has been the leader of a Lundbeck Foundation Centre of Excellence for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS) (January 2009–December 2021), which was partially financed by an independent grant from the Lundbeck Foundation based on international review and partially financed by the Mental Health Services in the Capital Region of Denmark, the University of Copenhagen, and other foundations. All grants are the property of the Mental Health Services in the Capital Region of Denmark and administrated by them.

ID: 385693468