TY - JOUR

T1 - Development and implementation of guidelines for the management of depression

T2 - a systematic review

AU - Lee, Yena

AU - Brietzke, Elisa

AU - Cao, Bing

AU - Chen, Yan

AU - Linnaranta, Outi

AU - Mansur, Rodrigo B

AU - Cortes, Paulina

AU - Kösters, Markus

AU - Majeed, Amna

AU - Tamura, Jocelyn K

AU - Lui, Leanna M W

AU - Vinberg, Maj

AU - Keinänen, Jaakko

AU - Kisely, Steve

AU - Naveed, Sadiq

AU - Barbui, Corrado

AU - Parker, Gary

AU - Owolabi, Mayowa

AU - Nishi, Daisuke

AU - Lee, JungGoo

AU - Srisurapanont, Manit

AU - Gill, Hartej

AU - Guo, Lan

AU - Balanzá-Martínez, Vicent

AU - Partonen, Timo

AU - Nolen, Willem A

AU - Lee, Jae-Hon

AU - Kim, Ji Hwan

AU - Chavannes, Niels H

AU - Ewais, Tatjana

AU - Atienza-Carbonell, Beatriz

AU - Silven, Anna V

AU - Yasuma, Naonori

AU - Gil, Artyom

AU - Novikov, Andrey

AU - Lacey, Cameron

AU - Versluis, Anke

AU - von Malortie, Sofia

AU - Chan, Lai Fong

AU - Waqas, Ahmed

AU - Purgato, Marianna

AU - Aardoom, Jiska Joëlle

AU - Ly-Uson, Josefina T

AU - Sim, Kang

AU - Tuineag, Maria

AU - van der Kleij, Rianne M J J

AU - van Luenen, Sanne

AU - Suttajit, Sirijit

AU - Hajek, Tomas

AU - Lee, Yu Wei

AU - Global Alliance for Chronic Diseases (GACD) Mental Health Guidelines Working Group

N1 - (c) 2020 The authors; licensee World Health Organization.

PY - 2020

Y1 - 2020

N2 - Objective: To evaluate the development and implementation of clinical practice guidelines for the management of depression globally.Methods: We conducted a systematic review of existing guidelines for the management of depression in adults with major depressive or bipolar disorder. For each identified guideline, we assessed compliance with measures of guideline development quality (such as transparency in guideline development processes and funding, multidisciplinary author group composition, systematic review of comparative efficacy research) and implementation (such as quality indicators). We compared guidelines from low- and middle-income countries with those from high-income countries.Findings: We identified 82 national and 13 international clinical practice guidelines from 83 countries in 27 languages. Guideline development processes and funding sources were explicitly specified in a smaller proportion of guidelines from low- and middle-income countries (8/29; 28%) relative to high-income countries (35/58; 60%). Fewer guidelines (2/29; 7%) from low- and middle-income countries, relative to high-income countries (22/58; 38%), were authored by a multidisciplinary development group. A systematic review of comparative effectiveness was conducted in 31% (9/29) of low- and middle-income country guidelines versus 71% (41/58) of high-income country guidelines. Only 10% (3/29) of low- and middle-income country and 19% (11/58) of high-income country guidelines described plans to assess quality indicators or recommendation adherence.Conclusion: Globally, guideline implementation is inadequately planned, reported and measured. Narrowing disparities in the development and implementation of guidelines in low- and middle-income countries is a priority. Future guidelines should present strategies to implement recommendations and measure feasibility, cost-effectiveness and impact on health outcomes.

AB - Objective: To evaluate the development and implementation of clinical practice guidelines for the management of depression globally.Methods: We conducted a systematic review of existing guidelines for the management of depression in adults with major depressive or bipolar disorder. For each identified guideline, we assessed compliance with measures of guideline development quality (such as transparency in guideline development processes and funding, multidisciplinary author group composition, systematic review of comparative efficacy research) and implementation (such as quality indicators). We compared guidelines from low- and middle-income countries with those from high-income countries.Findings: We identified 82 national and 13 international clinical practice guidelines from 83 countries in 27 languages. Guideline development processes and funding sources were explicitly specified in a smaller proportion of guidelines from low- and middle-income countries (8/29; 28%) relative to high-income countries (35/58; 60%). Fewer guidelines (2/29; 7%) from low- and middle-income countries, relative to high-income countries (22/58; 38%), were authored by a multidisciplinary development group. A systematic review of comparative effectiveness was conducted in 31% (9/29) of low- and middle-income country guidelines versus 71% (41/58) of high-income country guidelines. Only 10% (3/29) of low- and middle-income country and 19% (11/58) of high-income country guidelines described plans to assess quality indicators or recommendation adherence.Conclusion: Globally, guideline implementation is inadequately planned, reported and measured. Narrowing disparities in the development and implementation of guidelines in low- and middle-income countries is a priority. Future guidelines should present strategies to implement recommendations and measure feasibility, cost-effectiveness and impact on health outcomes.

U2 - 10.2471/BLT.20.251405

DO - 10.2471/BLT.20.251405

M3 - Review

C2 - 33177758

VL - 98

SP - 683-697H

JO - Bulletin of the World Health Organization

JF - Bulletin of the World Health Organization

SN - 0042-9686

IS - 10

ER -