Personalized medicine in psychiatry
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Personalized medicine in psychiatry. / Wium-Andersen, Ida Kim; Vinberg, Maj; Kessing, Lars Vedel; McIntyre, Roger S.
I: Nordic Journal of Psychiatry, Bind 71, Nr. 1, 01.2017, s. 12-19.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Personalized medicine in psychiatry
AU - Wium-Andersen, Ida Kim
AU - Vinberg, Maj
AU - Kessing, Lars Vedel
AU - McIntyre, Roger S.
PY - 2017/1
Y1 - 2017/1
N2 - Background: Personalized medicine is a model in which a patient’s unique clinical, genetic, and environmental characteristics are the basis for treatment and prevention. Aim, method, and results: This review aims to describe the current tools, phenomenological features, clinical risk factors, and biomarkers used to provide personalized medicine. Furthermore, this study describes the target areas in which they can be applied including diagnostics, treatment selection and response, assessment of risk of side-effects, and prevention. Discussion and conclusion: Personalized medicine in psychiatry is challenged by the current taxonomy, where the diagnostic categories are broad and great biological heterogeneity exists within each category. There is, thus, a gap between the current advanced research prospects and clinical practice, and the current taxonomy is, thus, a poor basis for biological research. The discussion proposes possible solutions to narrow this gap and to move psychiatric research forward towards personalized medicine.
AB - Background: Personalized medicine is a model in which a patient’s unique clinical, genetic, and environmental characteristics are the basis for treatment and prevention. Aim, method, and results: This review aims to describe the current tools, phenomenological features, clinical risk factors, and biomarkers used to provide personalized medicine. Furthermore, this study describes the target areas in which they can be applied including diagnostics, treatment selection and response, assessment of risk of side-effects, and prevention. Discussion and conclusion: Personalized medicine in psychiatry is challenged by the current taxonomy, where the diagnostic categories are broad and great biological heterogeneity exists within each category. There is, thus, a gap between the current advanced research prospects and clinical practice, and the current taxonomy is, thus, a poor basis for biological research. The discussion proposes possible solutions to narrow this gap and to move psychiatric research forward towards personalized medicine.
KW - Biomarkers
KW - diagnostic system
KW - genetics
KW - personalized medicine
KW - psychiatry
KW - RDoC
KW - taxonomy
U2 - 10.1080/08039488.2016.1216163
DO - 10.1080/08039488.2016.1216163
M3 - Review
C2 - 27564242
AN - SCOPUS:85006988034
VL - 71
SP - 12
EP - 19
JO - Nordisk Psykiatrisk Tidsskrift
JF - Nordisk Psykiatrisk Tidsskrift
SN - 0803-9496
IS - 1
ER -
ID: 180934816