Sedimentation of formed elements in distally ischaemic flaps

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Standard

Sedimentation of formed elements in distally ischaemic flaps. / Birk-Sørensen, L; Tromborg, H B; Kerrigan, C L; Solymoss, S; Hjortdal, V E.

I: Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, Bind 31, Nr. 3, 09.1997, s. 203-11.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Birk-Sørensen, L, Tromborg, HB, Kerrigan, CL, Solymoss, S & Hjortdal, VE 1997, 'Sedimentation of formed elements in distally ischaemic flaps', Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, bind 31, nr. 3, s. 203-11. https://doi.org/10.3109/02844319709051533

APA

Birk-Sørensen, L., Tromborg, H. B., Kerrigan, C. L., Solymoss, S., & Hjortdal, V. E. (1997). Sedimentation of formed elements in distally ischaemic flaps. Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, 31(3), 203-11. https://doi.org/10.3109/02844319709051533

Vancouver

Birk-Sørensen L, Tromborg HB, Kerrigan CL, Solymoss S, Hjortdal VE. Sedimentation of formed elements in distally ischaemic flaps. Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery. 1997 sep.;31(3):203-11. https://doi.org/10.3109/02844319709051533

Author

Birk-Sørensen, L ; Tromborg, H B ; Kerrigan, C L ; Solymoss, S ; Hjortdal, V E. / Sedimentation of formed elements in distally ischaemic flaps. I: Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery. 1997 ; Bind 31, Nr. 3. s. 203-11.

Bibtex

@article{0fcbb679701b47d2831d1ac9ac5834d6,
title = "Sedimentation of formed elements in distally ischaemic flaps",
abstract = "Our aim was to find out whether thrombosis has a key role in distally ischaemic flaps and whether heparin improves flap survival in distally ischaemic myocutaneous and pure skin flaps in pigs. In experiment 1 we measured the concentration of coagulation factors in the venous effluent from both viable flaps and distally ischaemic flaps. In experiment 2 radioactively labelled blood components (red cells, platelets and fibrinogen) were injected intravenously and the distribution of each tracer was measured. In experiment 3 either heparin or saline was given as a local, continuous direct intra-arterial infusion. Fluorescein was used in all experiments to estimate the eventual flap survival. Our results indicate that thrombosis is not an important factor in distal ischaemia, and that heparin did not improve survival. Instead, there seems to be selective pooling of formed elements in the ischaemic portion of the flap.",
keywords = "Animals, Anticoagulants/pharmacology, Blood Coagulation Factors/metabolism, Female, Heparin/pharmacology, Surgical Flaps/blood supply, Swine, Thrombosis/drug therapy",
author = "L Birk-S{\o}rensen and Tromborg, {H B} and Kerrigan, {C L} and S Solymoss and Hjortdal, {V E}",
year = "1997",
month = sep,
doi = "10.3109/02844319709051533",
language = "English",
volume = "31",
pages = "203--11",
journal = "Journal of Plastic Surgery and Hand Surgery",
issn = "2000-656X",
publisher = "Taylor & Francis",
number = "3",

}

RIS

TY - JOUR

T1 - Sedimentation of formed elements in distally ischaemic flaps

AU - Birk-Sørensen, L

AU - Tromborg, H B

AU - Kerrigan, C L

AU - Solymoss, S

AU - Hjortdal, V E

PY - 1997/9

Y1 - 1997/9

N2 - Our aim was to find out whether thrombosis has a key role in distally ischaemic flaps and whether heparin improves flap survival in distally ischaemic myocutaneous and pure skin flaps in pigs. In experiment 1 we measured the concentration of coagulation factors in the venous effluent from both viable flaps and distally ischaemic flaps. In experiment 2 radioactively labelled blood components (red cells, platelets and fibrinogen) were injected intravenously and the distribution of each tracer was measured. In experiment 3 either heparin or saline was given as a local, continuous direct intra-arterial infusion. Fluorescein was used in all experiments to estimate the eventual flap survival. Our results indicate that thrombosis is not an important factor in distal ischaemia, and that heparin did not improve survival. Instead, there seems to be selective pooling of formed elements in the ischaemic portion of the flap.

AB - Our aim was to find out whether thrombosis has a key role in distally ischaemic flaps and whether heparin improves flap survival in distally ischaemic myocutaneous and pure skin flaps in pigs. In experiment 1 we measured the concentration of coagulation factors in the venous effluent from both viable flaps and distally ischaemic flaps. In experiment 2 radioactively labelled blood components (red cells, platelets and fibrinogen) were injected intravenously and the distribution of each tracer was measured. In experiment 3 either heparin or saline was given as a local, continuous direct intra-arterial infusion. Fluorescein was used in all experiments to estimate the eventual flap survival. Our results indicate that thrombosis is not an important factor in distal ischaemia, and that heparin did not improve survival. Instead, there seems to be selective pooling of formed elements in the ischaemic portion of the flap.

KW - Animals

KW - Anticoagulants/pharmacology

KW - Blood Coagulation Factors/metabolism

KW - Female

KW - Heparin/pharmacology

KW - Surgical Flaps/blood supply

KW - Swine

KW - Thrombosis/drug therapy

U2 - 10.3109/02844319709051533

DO - 10.3109/02844319709051533

M3 - Journal article

C2 - 9299681

VL - 31

SP - 203

EP - 211

JO - Journal of Plastic Surgery and Hand Surgery

JF - Journal of Plastic Surgery and Hand Surgery

SN - 2000-656X

IS - 3

ER -

ID: 243521943