The microcirculation of myocutaneous island flaps in pigs studied with radioactive blood volume tracers and microspheres of different sizes

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

The microcirculation of myocutaneous island flaps in pigs studied with radioactive blood volume tracers and microspheres of different sizes. / Hjortdal, V E; Hansen, E S; Henriksen, T B; Kjølseth, D; Søballe, K; Djurhuus, J C.

I: Plastic and Reconstructive Surgery, Bind 89, Nr. 1, 01.1992, s. 116-22; discussion 123-4.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hjortdal, VE, Hansen, ES, Henriksen, TB, Kjølseth, D, Søballe, K & Djurhuus, JC 1992, 'The microcirculation of myocutaneous island flaps in pigs studied with radioactive blood volume tracers and microspheres of different sizes', Plastic and Reconstructive Surgery, bind 89, nr. 1, s. 116-22; discussion 123-4.

APA

Hjortdal, V. E., Hansen, E. S., Henriksen, T. B., Kjølseth, D., Søballe, K., & Djurhuus, J. C. (1992). The microcirculation of myocutaneous island flaps in pigs studied with radioactive blood volume tracers and microspheres of different sizes. Plastic and Reconstructive Surgery, 89(1), 116-22; discussion 123-4.

Vancouver

Hjortdal VE, Hansen ES, Henriksen TB, Kjølseth D, Søballe K, Djurhuus JC. The microcirculation of myocutaneous island flaps in pigs studied with radioactive blood volume tracers and microspheres of different sizes. Plastic and Reconstructive Surgery. 1992 jan.;89(1):116-22; discussion 123-4.

Author

Hjortdal, V E ; Hansen, E S ; Henriksen, T B ; Kjølseth, D ; Søballe, K ; Djurhuus, J C. / The microcirculation of myocutaneous island flaps in pigs studied with radioactive blood volume tracers and microspheres of different sizes. I: Plastic and Reconstructive Surgery. 1992 ; Bind 89, Nr. 1. s. 116-22; discussion 123-4.

Bibtex

@article{bd5def5131d04405866ad809e92a8520,
title = "The microcirculation of myocutaneous island flaps in pigs studied with radioactive blood volume tracers and microspheres of different sizes",
abstract = "In order to further improve the understanding of hemodynamic changes in the immediate postoperative phase after elevation of myocutaneous flaps, regional blood flow and arteriovenous (A-V) shunting were measured in rectus abdominis island flaps in 8 pigs. Radioactive microspheres of two sizes (15 and 50 micron) were used. Approximately half (53.4 +/- 6 percent) of the 15-micron microspheres and one-fourth (24.1 +/- 6 percent) of the 50-micron microspheres entering the flap appeared in the venous outflow. Compared with the control area, A-V shunting was significantly increased in muscle and substantially more pronounced in skin. Nutritional blood flow, total blood flow, and vascular volume were increased in muscle and unchanged in skin and subcutis. The lowest tissue hematocrit of 7 +/- 1 percent was found in skin as compared with a central hematocrit of 35 +/- 2 percent. Tissue hematocrit in flap muscle was decreased to 17 +/- 2 percent when compared with control muscle (22 +/- 3 percent), and the mean transit time for blood was correspondingly decreased. Thus vasodilation provided increased perfusion through muscular capillaries and through A-V shunts. Shunting of 15-micron microspheres appeared to take place not only in skin, but also in subcutis and muscle, which challenges the widespread belief that A-V shunting does not occur in muscle.",
keywords = "Animals, Blood Volume, Chromium Radioisotopes, Iodine Radioisotopes, Male, Microcirculation/physiology, Microspheres, Regional Blood Flow, Surgical Flaps/physiology, Swine",
author = "Hjortdal, {V E} and Hansen, {E S} and Henriksen, {T B} and D Kj{\o}lseth and K S{\o}balle and Djurhuus, {J C}",
year = "1992",
month = jan,
language = "English",
volume = "89",
pages = "116--22; discussion 123--4",
journal = "Plastic and Reconstructive Surgery",
issn = "0032-1052",
publisher = "Lippincott Williams & Wilkins",
number = "1",

}

RIS

TY - JOUR

T1 - The microcirculation of myocutaneous island flaps in pigs studied with radioactive blood volume tracers and microspheres of different sizes

AU - Hjortdal, V E

AU - Hansen, E S

AU - Henriksen, T B

AU - Kjølseth, D

AU - Søballe, K

AU - Djurhuus, J C

PY - 1992/1

Y1 - 1992/1

N2 - In order to further improve the understanding of hemodynamic changes in the immediate postoperative phase after elevation of myocutaneous flaps, regional blood flow and arteriovenous (A-V) shunting were measured in rectus abdominis island flaps in 8 pigs. Radioactive microspheres of two sizes (15 and 50 micron) were used. Approximately half (53.4 +/- 6 percent) of the 15-micron microspheres and one-fourth (24.1 +/- 6 percent) of the 50-micron microspheres entering the flap appeared in the venous outflow. Compared with the control area, A-V shunting was significantly increased in muscle and substantially more pronounced in skin. Nutritional blood flow, total blood flow, and vascular volume were increased in muscle and unchanged in skin and subcutis. The lowest tissue hematocrit of 7 +/- 1 percent was found in skin as compared with a central hematocrit of 35 +/- 2 percent. Tissue hematocrit in flap muscle was decreased to 17 +/- 2 percent when compared with control muscle (22 +/- 3 percent), and the mean transit time for blood was correspondingly decreased. Thus vasodilation provided increased perfusion through muscular capillaries and through A-V shunts. Shunting of 15-micron microspheres appeared to take place not only in skin, but also in subcutis and muscle, which challenges the widespread belief that A-V shunting does not occur in muscle.

AB - In order to further improve the understanding of hemodynamic changes in the immediate postoperative phase after elevation of myocutaneous flaps, regional blood flow and arteriovenous (A-V) shunting were measured in rectus abdominis island flaps in 8 pigs. Radioactive microspheres of two sizes (15 and 50 micron) were used. Approximately half (53.4 +/- 6 percent) of the 15-micron microspheres and one-fourth (24.1 +/- 6 percent) of the 50-micron microspheres entering the flap appeared in the venous outflow. Compared with the control area, A-V shunting was significantly increased in muscle and substantially more pronounced in skin. Nutritional blood flow, total blood flow, and vascular volume were increased in muscle and unchanged in skin and subcutis. The lowest tissue hematocrit of 7 +/- 1 percent was found in skin as compared with a central hematocrit of 35 +/- 2 percent. Tissue hematocrit in flap muscle was decreased to 17 +/- 2 percent when compared with control muscle (22 +/- 3 percent), and the mean transit time for blood was correspondingly decreased. Thus vasodilation provided increased perfusion through muscular capillaries and through A-V shunts. Shunting of 15-micron microspheres appeared to take place not only in skin, but also in subcutis and muscle, which challenges the widespread belief that A-V shunting does not occur in muscle.

KW - Animals

KW - Blood Volume

KW - Chromium Radioisotopes

KW - Iodine Radioisotopes

KW - Male

KW - Microcirculation/physiology

KW - Microspheres

KW - Regional Blood Flow

KW - Surgical Flaps/physiology

KW - Swine

M3 - Journal article

C2 - 1727241

VL - 89

SP - 116-22; discussion 123-4

JO - Plastic and Reconstructive Surgery

JF - Plastic and Reconstructive Surgery

SN - 0032-1052

IS - 1

ER -

ID: 244280372