Tissue oxygen tension in myocutaneous flaps. Correlation with blood flow and blood gases
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Tissue oxygen tension in myocutaneous flaps. Correlation with blood flow and blood gases. / Hjortdal, V E; Henriksen, T B; Kjølseth, D; Hansen, E S; Djurhuus, J C; Gottrup, F.
I: European Journal of Surgery Supplement, Bind 157, Nr. 5, 05.1991, s. 307-11.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Tissue oxygen tension in myocutaneous flaps. Correlation with blood flow and blood gases
AU - Hjortdal, V E
AU - Henriksen, T B
AU - Kjølseth, D
AU - Hansen, E S
AU - Djurhuus, J C
AU - Gottrup, F
PY - 1991/5
Y1 - 1991/5
N2 - The relationship between tissue oxygen tension (PO2) and blood flow, blood gas tensions, oxygen delivery, and oxygen consumption was investigated in myocutaneous island flaps in 24 pigs. The tissue PO2 was measured by the silicone rubber tonometer technique. Capillary blood flow was increased during the first 3-4 hours after implantation of tonometers and they must, therefore, be implanted 3-4 hours before use. After raising the flap, mean (SEM) total flap blood flow increased from 11.2 (0.8) ml/min to 16.0 (1.3) ml/min within the first three hours. Mean (SEM) subcutaneous tissue PO2 decreased from 9.5 (0.6) kPa to 5.2 (0.7) kPa over six hours after the procedure, whereas muscle PO2, blood oxygen tension, and arteriovenous oxygen difference were unchanged. Hence, both the supply to, and use of oxygen in, the flap increased. Muscular and subcutaneous oxygen tensions were about 3 and 1 kPa, respectively, lower than venous oxygen tension. Tissue PO2 did not correlate with blood flow, blood oxygen tensions, arteriovenous differences in oxygen tension, or with oxygen supply in a cross section of animals. Tissue PO2 seems to reflect accurately the balance between oxygen supply and consumption, which might be the most useful indicator for continuous flap monitoring.
AB - The relationship between tissue oxygen tension (PO2) and blood flow, blood gas tensions, oxygen delivery, and oxygen consumption was investigated in myocutaneous island flaps in 24 pigs. The tissue PO2 was measured by the silicone rubber tonometer technique. Capillary blood flow was increased during the first 3-4 hours after implantation of tonometers and they must, therefore, be implanted 3-4 hours before use. After raising the flap, mean (SEM) total flap blood flow increased from 11.2 (0.8) ml/min to 16.0 (1.3) ml/min within the first three hours. Mean (SEM) subcutaneous tissue PO2 decreased from 9.5 (0.6) kPa to 5.2 (0.7) kPa over six hours after the procedure, whereas muscle PO2, blood oxygen tension, and arteriovenous oxygen difference were unchanged. Hence, both the supply to, and use of oxygen in, the flap increased. Muscular and subcutaneous oxygen tensions were about 3 and 1 kPa, respectively, lower than venous oxygen tension. Tissue PO2 did not correlate with blood flow, blood oxygen tensions, arteriovenous differences in oxygen tension, or with oxygen supply in a cross section of animals. Tissue PO2 seems to reflect accurately the balance between oxygen supply and consumption, which might be the most useful indicator for continuous flap monitoring.
KW - Animals
KW - Blood Flow Velocity/physiology
KW - Oxygen/analysis
KW - Oxygen Consumption/physiology
KW - Regional Blood Flow/physiology
KW - Surgical Flaps/physiology
KW - Swine
KW - Time Factors
M3 - Journal article
C2 - 1678642
VL - 157
SP - 307
EP - 311
JO - European Journal of Surgery, Acta Chirurgica, Supplement
JF - European Journal of Surgery, Acta Chirurgica, Supplement
SN - 1102-416X
IS - 5
ER -
ID: 244328196