Laser systems for ablative fractional resurfacing
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Laser systems for ablative fractional resurfacing. / Paasch, Uwe; Haedersdal, Merete.
I: Expert Review of Medical Devices, Bind 8, Nr. 1, 2011, s. 67-83.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Laser systems for ablative fractional resurfacing
AU - Paasch, Uwe
AU - Haedersdal, Merete
PY - 2011
Y1 - 2011
N2 - Ablative fractional resurfacing (AFR) creates microscopic vertical ablated channels that are surrounded by a thin layer of coagulated tissue, constituting the microscopic treatment zones (MTZs). AFR induces epidermal and dermal remodeling, which raises new possibilities for the treatment of a variety of skin conditions, primarily chronically photodamaged skin, but also acne and burn scars. In addition, it is anticipated that AFR can be utilized in the laser-assisted delivery of topical drugs. Clinical efficacy coupled with minimal downtime has driven the development of various fractional ablative laser systems. Fractionated CO(2) (10,600-nm), erbium yttrium aluminum garnet, 2940-nm and yttrium scandium gallium garnet, 2790-nm lasers are available. In this article, we present an overview of AFR technology, devices and histopathology, and we summarize the current clinical possibilities with AFR incorporating our personal experience. AFR is still in the exploratory era, and systematic investigations of clinical outcomes related to various system settings are needed.
AB - Ablative fractional resurfacing (AFR) creates microscopic vertical ablated channels that are surrounded by a thin layer of coagulated tissue, constituting the microscopic treatment zones (MTZs). AFR induces epidermal and dermal remodeling, which raises new possibilities for the treatment of a variety of skin conditions, primarily chronically photodamaged skin, but also acne and burn scars. In addition, it is anticipated that AFR can be utilized in the laser-assisted delivery of topical drugs. Clinical efficacy coupled with minimal downtime has driven the development of various fractional ablative laser systems. Fractionated CO(2) (10,600-nm), erbium yttrium aluminum garnet, 2940-nm and yttrium scandium gallium garnet, 2790-nm lasers are available. In this article, we present an overview of AFR technology, devices and histopathology, and we summarize the current clinical possibilities with AFR incorporating our personal experience. AFR is still in the exploratory era, and systematic investigations of clinical outcomes related to various system settings are needed.
U2 - http://dx.doi.org/10.1586/erd.10.74
DO - http://dx.doi.org/10.1586/erd.10.74
M3 - Review
VL - 8
SP - 67
EP - 83
JO - Expert Review of Medical Devices
JF - Expert Review of Medical Devices
SN - 1743-4440
IS - 1
ER -
ID: 40161175